Alberto Pacheco, Ph.D.

Biografía

Dr. Pacheco is the Director of the Andrology Laboratory and the Sperm Bank at IVI Madrid, IVI Valladolid and IVI Salamanca. He is also assistant professor of Immunology at Alfonso X “El Sabio” University in Madrid since 2000. He completed his Bachelor’s degree in Biology in 1992, and obtained his Ph.D. in Biological Sciences in 1997, both from the Complutense University, in Madrid. He also received a Masters degree in Reproductive Medicine in 2005.

As a researcher, his areas of interest includ molecular markers of male and female infertility, sperm DNA fragmentation, laboratory QA/QC, peripheral and uterine natural killer (NK) cell characterization in women with recurrent miscarriages and implantation failure. Dr Pacheco has published over 25 original peer review articles in leading reproductive journals, many of these were in Immunology journals. He also contributed several book chapters and made over 80 presentations at national and international scientific meetings.
Dr. Pacheco is the recipient of several grants from public and private organizations in Spain (FIS Projects, CDTI), and serves as reviewer in reproductive journals including Fertility Sterility, RBM online, Asian Journal of Andrology, Journal of Assisted Reproduction and Genetics and Journal of Cellular and Molecular Medicine. He has also served on the executive board of Andrology Special Interest Group in the Spanish Society for Reproductive Biology (ASEBIR).
Dr. Pacheco has been involved in teaching since his early career, and has a number of teaching commitments. He is among the faculty for a number of post graduate/Masters courses in Human Reproduction, provided by Spanish Fertility Society, Rey Juan Carlos University of Madrid, University of Valencia, and Europea University of Madrid. Dr. Pacheco is also the coordinator of Immunology courses for students enrolled in Medicine, Pharmacy and Veterinary degrees at Alfonso X “El Sabio” University of Madrid.

Publicaciones

Distress response in granulosa cells of women affected by PCOS with or without insulin resistance.
Cozzolino M, Herraiz S, Cakiroglu Y, Garcia-Velasco JA, Tiras B, Pacheco A, Rabadan S, Kohls G, Barrio AI, Pellicer A, Seli E

Endocrine. 2022 Sep 23. 2022 doi: 10.1007/s12020-022-03192-8

Effects of age and oligoasthenozoospermia on telomeres of sperm and blood cells.
Balmori C, Cordova-Oriz I, De Alba G, Medrano M, Jiménez-Tormo L, Polonio AM, Chico-Sordo L, Pacheco A, García-Velasco JA, Varela E

Reprod Biomed Online. 2021 Oct 25:S1472-6483(21)00524-1. Online ahead of print. 2022 doi: 10.1016/j.rbmo.2021.10.010

Immune and spermatogenesis-related loci are involved in the development of extreme patterns of male infertility.
Cerván-Martín M, Tüttelmann F, Lopes AM, Bossini-Castillo L, Rivera-Egea R, Garrido N, Lujan S, Romeu G, Santos-Ribeiro S, Castilla JA, Carmen Gonzalvo M, Clavero A, Maldonado V, Vicente FJ, González-Muñoz S, Guzmán-Jiménez A, Burgos M, Jiménez R, Pacheco A, González C, Gómez S, Amorós D, Aguilar J, Quintana F, Calhaz-Jorge C, Aguiar A, Nunes J, Sousa S, Pereira I, Pinto MG, Correia S, Sánchez-Curbelo J, López-Rodrigo O, Martín J, Pereira-Caetano I, Marques PI, Carvalho F, Barros A, Gromoll J, Bassas L, Seixas S, Gonçalves J, Larriba S, Kliesch S, Palomino-Morales RJ, Carmona FD

Commun Biol. 2022 Nov 10;5(1):1220. doi: 10.1038/s42003-022-04192-0.. 2022 doi:

Presentaciones

Agudo D Castro E Pacheco A Irene Martín Patón Cruz M Bronet F O-107 DOES TOBACCO AFFECT FOLLICULAR AND EMBRYO HEALTH?. Presented at 76th American Society of Reproductive Medicine Scientific Congress, Virtual congress, October 17-21,2020

Hervas I Garrido N Rivera-Egea R Gonzalez-Ravina C Amoros D Quintana F Gil Julia M Pacheco A O-105 ACCURATE MEASUREMENT OF SPERM DNA FRAGMENTATION EFFECT ON REPRODUCTIVE OUTCOMES BY CUMULATIVE LIVEBIRTH RATES (CLBR) PER EMBRYO TRANSFERRED AND OOCYTE UTILIZED REVEALS ITS LACK OF RELEVANCE IN OOCYTE DONATION FOR UNSELECTED MALES.. Presented at 76th American Society of Reproductive Medicine Scientific Congress, Virtual congress, October 17-21,2020

Hervas I Garrido N Rivera-Egea R Gonzalez-Ravina C Amoros D Quintana F Gil Julia M Pacheco A P-14 REALISTIC MEASUREMENT OF THE EFFECT OF SPERM DNA FRAGMENTATION ON REPRODUCTIVE OUTCOMES BY CUMULATIVE LIVEBIRTH RATES (CLBR) PER EMBRYO REPLACED AND OOCYTE EMPLOYED REVEALS ITS LACK OF RELEVANCE IN UNSELECTED MALES USING OWN OOCYTES.. Presented at 76th American Society of Reproductive Medicine Scientific Congress, Virtual congress, October 17-21,2020

Gil Julia M Quintana F Amoros D Pacheco A Gonzalez-Ravina C Rivera-Egea R Hervas I Garrido N P-117 CLINICALLY IRRELEVANT EFFECT OF NON-APOPTOTIC SPERM SELECTION BY MAGNETIC ACTIVATED CELL SORTING BEFORE INTRACYTOPLASMIC SPERM INJECTION IN DONATED OOCYTES,AS MEASURED BY CUMULATIVE LIVE BIRTH RATES.. Presented at 76th American Society of Reproductive Medicine Scientific Congress, Virtual congress, October 17-21,2020

Gil Julia M Quintana F Amoros D Pacheco A Gonzalez-Ravina C Rivera-Egea R Hervas I Garrido N P-16 SEPARATION OF NON-APOPTOTIC SPERM VIA MAGNETIC ACTIVATED CELL SORTING BEFORE INTRACYTOPLASMIC SPERM INJECTION IN AUTOLOGOUS OOCYTES INCREASED CUMULATIVE LIVE BIRTH RATES WITH LIMITED CLINICAL IMPACT.. Presented at 76th American Society of Reproductive Medicine Scientific Congress, Virtual congress, October 17-21,2020

Córdova-Oriz I García-Panadero R Guillermo De Alba Pacheco A Carlos Balmori Chico-Sordo L Polonio AM Marta Medrano Garcia-Velasco JA Thomas M D’Hooghe Varela E Psathas P P-956 OLDER OLIGOASTHENOZOOSPERMIC MEN HAVE ALTERED TELOMERE BIOLOGY AND LESS CHANCES THAN CONTROLS FOR ASSISTED REPRODUCTIVE TECHNOLOGY OUTCOMES (ART).. Presented at 76th American Society of Reproductive Medicine Scientific Congress, Virtual congress, October 17-21,2020

Ortega I Alvarez de la Fuente A Sonia Matey Elizabet Henzenn Cruz M Pacheco A Antoni Duleba Garcia-Velasco JA P-854 RESVERATROL FOR PREVENTING OVARIAN HYPERSTIMULATION SYNDROME IN WOMEN AT RISK UNDERGOING EGG DONATION: A RANDOMIZED CONTROLLED STUDY. Presented at 76th American Society of Reproductive Medicine Scientific Congress, Virtual congress, October 17-21,2020

Alecsandru D Pacheco A Garrido N Barrio A Aparicio P Pellicer A Garcia-Velasco JA An increased % of CD56+CD16+ NK cells in the endometrial biopsy is not related with recurrent miscarriage when maternal KIR are considered. Presented at the 36th annual meeting of the European Society of Human Reproduction and Embryology, Copenhagen,Denmark, July 5-8,2020

Cerrillo M Cecchino GN María Cruz Mayoral M Pacheco A Labarta E García-Velasco JA O-171 Comparison of day-5 serum progesterone levels using different routes of administration for artificial endometrial preparation: is there any significant intrapatient variation?. Presented at the 36th annual meeting of the European Society of Human Reproduction and Embryology, Copenhagen,Denmark, July 5-8,2020

Arnanz A De Munck N El Khatib I Bayram A El-Damen A Abdala A Melado L Lawrenz B Pacheco A Fatemi H Vitamin D (VitD) in follicular fluid (FF) correlates with the euploid status of the embryo in a VitD deficient Middle Eastern population. Presented at the 36th annual meeting of the European Society of Human Reproduction and Embryology, Copenhagen,Denmark, July 5-8,2020

Cecchino G Pacheco A O-81 THE EFFECT OF AGE ON BIOENERGETICS OF HUMAN GRANULOSA CELLS 2019

Esbert M Soares SR Pacheco A Ballesteros A Florensa M Meseguer M Human zygotes respond to sperm dna damage by delaying embryonic development 2018

Alecsandru D Pacheco A Fabris A Barrio A Aparicio P García-Velasco J Ovarian stimulation doesn’t influence the uterine immune environment in healthy infertile women 2018

Alecsandru D Iglesias C Pacheco A Barrio A Garrido N Garcia Velasco J HLA-C haplotypes distribution among gametes donors in our population 2018

Alecsandru D Pacheco A Garrido N Barrio A Aparicio P Pellicer A Garcia Velasco J Live birth rate after oocyte donation is influenced by donor HLA-C: one step beyond conventional markers of success 2017

Sánchez M Pacheco A Cruz M Requena A Assessment of sperm ploidy status by flow cytommetry correlates to embryo quality 2017

Investigación en Fertilidad

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