Emre Seli, M.D.
RMA New Jersey
Emre Seli, MD, is Research Director at IVI RMA Global and Professor of Obstetrics, Gynecology, and Reproductive Sciences at Yale School of Medicine. Dr. Seli received his medical degree from the University of Istanbul and completed his Residency in Obstetrics and Gynecology at Yale University. His postdoctoral training included a fellowship in Reproductive Endocrinology and Infertility as well as a research fellowship in molecular biology, both at Yale University.
The primary focus of his research program is to understand and treat infertility. His laboratory characterized mechanisms regulating translational activation of gene expression in the oocyte. Dr. Seli and his colleagues also made seminal contributions to our understanding of oocyte and embryo competence in IVF and the potential role of non-invasive diagnostic technologies in this context. Dr. Seli is the recipient of many National Institutes of Health (NIH) and pharmaceutical industry-sponsored research grants. He has trained more than 50 pre- and post-doctoral fellows, published more than 100 scientific articles, and received numerous research awards, including the Ira and Ester Rosenwaks New Investigator Award from the American Society for Reproductive Medicine (ASRM), and the President’s Achievement Award from the Society for Reproductive Investigation (SRI). Dr. Seli’s current research focuses on determinants of oocyte and embryo health, and mechanisms of ovarian ageing.
Dr. Seli is actively involved in professional societies and scientific journals. He served as the Program Director for SRI 2016, where he is now the Program Committee Chair (2016-2021). He has also been a member of the ASRM Research Committee for the past 5 years, and served as the member of the SSR Program Committee, where he organized the Ovarian Workshop in 2016 and 2018. He is/was associate editor for Molecular Human Reproduction, Reproductive Sciences, Journal of Assisted Reproduction and Genetics, and Reproductive Biomedicine Online and is currently co-editor of Current Opinion in Obstetrics and Gynecology.
As an educator, Dr. Seli delivered more than 150 invited lectures nationally and internationally, and he is the recipient of the “Association of Professors of Gynecology and Obstetrics (APGO) Excellence in Teaching Award” based on evaluations of his lectures by Yale Medical Students. Dr. Seli edited four books (Non-invasive Management of Gynecologic Disorders, Infertility, Fertility Preservation, and Human Gametes and Pre-implantation Embryos: Assessment and Diagnosis), and is currently co-authoring the 9th edition of the most acclaimed book in the field, “Speroff’s Clinical Gynecologic Endocrinology and Infertility“.
Honors and recognition
|SRI/Pfizer President’s Presenter Award, Society for Reproductive Investigation (SRI) to Scott Morin (mentor)||2018|
|SRI/Pfizer President’s Presenter Award, Society for Reproductive Investigation (SRI) to Man Zhang (mentor)||2018|
|Best Doctors in America||2017|
|Star Award, American Society for Reproductive Medicine (ASRM)||2017|
|SRI/Pfizer President’s Presenter Award, Society for Reproductive Investigation (SRI) to Tianren Wang (mentor)||2017|
|ASRM In-Training Award for Research. American Society for Reproductive Medicine (ASRM) to Tianren Wang (mentor)||2016|
|Best Doctors in America||2016|
|Star Award, American Society for Reproductive Medicine (ASRM)||2016|
|President’s Achievement Award, Society for Reproductive Investigation (SRI)||2016|
|SRI/Pfizer President’s Presenter Award, Society for Reproductive Investigation (SRI) to Katie Lowther (mentor)||2016|
|SRI/Pfizer President’s Presenter Award, Society for Reproductive Investigation (SRI) to Elnur Babayev (mentor)||2016|
|Best Doctors in America||2015|
|Star Award, American Society for Reproductive Medicine (ASRM)||2015|
|Best New Investigator Poster Award, Society for Reproductive Investigation (SRI) to Katie Lowther (mentor)||2015|
|Master of Arts, Privatim. Yale University, New Haven, CT, USA||2015|
|Excellence in Teaching Award, Association of Professors of Gynecology and Obstetrics (APGO) and Department of Obstetrics and Gynecology, Yale School of Medicine||2013|
|Ira and Ester Rosenwaks New Investigator Award, American Society for Reproductive Medicine (ASRM)||2009|
|Co-investigator for Basic Science Award, European Society of Human Reproduction and Embryology (ESHRE)||2008|
|Faculty Teaching Award for Medical Student Education, Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine.||2007|
|Lee Buxton Award for Medical Student Education, Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine||2006|
|Mentored Clinical Scientist Development (K08) Award, National Institute of Health (NIH)||2003|
|President’s Presenter Award, Society for Reproductive Investigation (formerly Society for Gynecologic Investigation) (SRI)||2002|
|John J. Meehan-Clifford R. Miller Award for academic excellence, Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine||2001|
|Residents of Excellence Award for outstanding resident research by a graduating resident, Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine||2001|
|The Society of Laparoendoscopic Surgeons “Outstanding Laparo-endoscopic Resident Surgeon Award”||2001|
|President’s Presenter Award, Society for Reproductive Investigation (formerly Society for Gynecologic Investigation) (SRI)||2000|
|ACOG/Novartis Fellowship Award for Research in Endocrinology of Postreproductive Woman||1999-2000|
|NAMS/Solvay Pharmaceuticals Corporation Fellowship Grant Award.||1999|
|Ranked top 1% in the national residency entrance examination (among 14,000 medical school graduates) in Turkey||1993|
|MISC European scholarship award for visiting student at Free University, Amsterdam, Holland.||1990|
|Sabanci scholarship for outstanding first year medical student.||1985|
|Ranked top 1% in nationwide university entrance examination (among 600,000) in Turkey||1984|
Metabolism of the oocyte and the preimplantation embryo: implications for assisted reproduction.
Scott RT Zhang M Seli E
Curr Opin Obstet Gynecol. Jun;30(3):163-170. 2018.
Diminished ovarian reserve and poor response to stimulation in patients <38 years old: a quantitative but not qualitative reduction in performance.
Morin SJ Patounakis G Juneau CR Neal SA Scott RT Seli E
Hum Reprod, 33(8):1489-1498, 2018.
Gonadotropin-Releasing Hormone Analogs for Gonadal Protection During Gonadotoxic Chemotherapy: A Systematic Review and Meta-Analysis.
Sofiyeva N Siepmann T Barlinn K Seli E Ata B
Reprod Sci. 1:1933719118799203. 2018.
Metabolic imaging with the use of fluorescence lifetime imaging microscopy (FLIM) accurately detects mitochondrial dysfunction in mouse oocytes
Sanchez T Wang T Pedro MV Zhang M Esencan E Sakkas D Needleman D Seli E
Fertil Steril, 110(7):1387-1397. 2018.
DNA methylation-based age prediction and telomere length in white blood cells and cumulus cells of infertile women with normal or poor response to ovarian stimulation.
Morin SJ Tao X Marin D Zhan Y Landis J Bedard J Scott RT Seli E
Aging (Albany NY), 10(12):3761-3773, 2018.
How new technical knowledge impacts clinical approach to infertile patients.
García-Velasco JA Seli E
Curr Opin Obstet Gynecol, 30(3):137-138, 2018.
Mitochondrial unfolded protein response gene Clpp is required to maintain ovarian follicular reserve during aging, for oocyte competence, and development of pre-implantation embryos.
Wang T Babayev E, Jiang Z Li G Zhang M Esencan E Horvath T Seli E
Aging Cell, 30:e12784. doi: 10.1111/acel.12784, 2018.
The role of mitochondrial activity in female fertility and assisted reproductive technologies: overview and current insights.
Cecchino GN Seli E Alves da Motta EL García-Velasco JA
Reprod Biomed Online, 36(6):686-697, 2018.
Translational Regulation of Gene Expression During Oogenesis and Pre-Implantation Embryo Development
Esencan E Seli E
Human Reproductive and Prenatal Genetics, P.C.K. Leung and J. Qiao eds., 2018.
Mitochondrial dysfunction and ovarian senescence
Wang T Zhang M Jiang Z Seli E
Am J Reprod Immunol, 77(5), 2017
Freeze all strategy in assisted reproduction: why it is not warranted?
Ata B Seli E
Curr Opin Obstet Gynecol, 28:149-50, 2017.
Endocrine causes of implantation failure.
Morin SJ Ata B Seli E
In: J Franasiak, R.T. Scott eds. Recurrent implantation failure. Springer/Humana Press, Berlin, Germany, 2017.
Embryonic poly(A)-binding protein (EPAB) is important at the preantral stage of mouse folliculogenesis for oocyte-somatic communication.
Lowther KM Favero F Yang C Taylor HS Seli E
Biol Reprod, 96:341-51, 2017.
IVF: progress through Technology development .
García-Velasco JA Seli E
Curr Opin Obstet Gynecol, 28:149-50, 2016.
Same-sex reproduction: Medical treatment options and psychosocial considerations.
Greenfeld DA Seli E
Curr Opin Obstet Gynecol. 2016 Jun;28(3):202-5. doi: 10.1097/GCO.0000000000000266.
Cross-talk between FSH and endoplasmic reticulum stress: a mutually suppressive relationship.
Babayev E Favero F Lalioti M Seli E
Reprod Sci, 23:352-64, 2016
Aging is associated with changes in mitochondrial dynamics, function and mtDNA quantity.
Babayev E Wang T Szigeti-Buck K Lowther K Taylor HS Horvath T Seli E
Maturitas, 93:121-130, 2016.
Mitochondrial DNA as a biomarker for in vitro fertilization (IVF) outcome
Curr Opin Obstet Gynecol, 28:158-63, 2016.
Same-sex reproduction:Medical treatment options and psychosocial considerations.
Greenfeld D Seli E
Poor ovarian response in women undergoing in vitro fertilization (IVF) is associated with altered micro RNA expression in cumulus cells.
Karakaya C Guzeloglu-Kayisli O Uyar A Kallen AN Babayev E Bozkurt N Unsal E Karabacak O Seli E
Fertil Steril, 103:1469-76, 2015.
Embryonic poly(A)-binding protein (EPAB) is required for EGF signaling and cumulus expansion in female mice.
Yang C Lowther KM Lalioti MD Seli E
Endocrinology, 157:405-16, 2015.
Oocyte mitochondrial function and reproduction.
Babayev E Seli E
Curr Opin Obstet Gynecol, 27:175-81, 2015.
IVF: a short but exciting story.
García-Velasco JA Seli E
Curr Opin Obstet Gynecol, 27:165-6, 2015.
Strategies for controlled ovarian stimulation in the setting of ovarian ageing.
Ata B Seli E
Semin Reprod Med, 33:436-48, 2015.
Oocyte cryopreservation as a preventive measure for age-related fertility loss.
Cil AP Turkgeldi L Seli E
Semin Reprod Med, 33:429-35, 2015.
Semin Reprod Med, 33:375-6, 2015.
Human embryonic poly(A) binding protein (EPAB) alternative splicing is differentially regulated in human oocytes and embryos.
Guzeloglu-Kayisli O Lalioti MD Babayev E Torrealday S Karakaya C Seli E
Mol Hum Reprod, 20(1):59-65, 2014
Epab is dispensable for Spermatogenesis and Male Fertility in Mice.
Ozturk S Guzeloglu-Kayisli O Lowther K Lalioti MD Sakkas D Seli E
Mol Reprod Dev, 81:390, 2014. *equal first authors.
Non-invasive prediction of embryonic sex in cattle by metabolomic analysis of in vitro culture medium with Fourier transfrom infrared spectroscopy.
Muñoz M Uyar A Correia E Díez C Fernandez A Caamaño JN Trigal B Carrocera S Seli E Gomez E
Metabolomics, 10:443-51, 2014. *equal first authors.
Metabolomic prediction of pregnancy viability in superovulated cattle embryos and recipients with fourier transform infrared spectroscopy
Muñoz M Uyar A Correia E Ponsart C Guyader-Joly C Martínez-Bello D Marquant-Le Guienne B Fernandez-Gonzalez A Díez C Caamaño JN Trigal B Humblot P Carrocera S Martin D Seli E Gomez E
Biomed Res Int, 2014:608579, 2014. *equal first authors.
Prediction of pregnancy viability in bovine in vitro-produced embryos and recipient plasma with Fourier transform infrared spectroscopy.
Muñoz M Uyar A Correia E Díez C Fernandez-Gonzalez A Caamaño JN Martínez-Bello D Trigal B Humblot P Ponsart C Guyader-Joly C Carrocera S Martin D Le Guienne BM Seli E Gomez E
J Dairy Sci, 97:5497-507, 2014. *equal first authors.
Follicle stimulating hormone receptor (FSHR) alternative skipping of exon 2 or 3 affects ovarian response to FSH.
Karakaya C Guzeloglu-Kayisli O Hobbs R Gerasimova T Uyar A Erdem M Oktem M Erdem A Gumuslu S Ercan D Sakkas D Comizzoli P Seli E Lalioti MD
Mol Hum Reprod, 20:630-43 2014
The expression of mRNA-binding protein TIA-1 is down-regulated in ectopic endometrium.
Karalok HM Aydin E Saglam O Torun A Guzeloglu-Kayisli O Lalioti MD Kristansson H Duke CMP Choe G Flannery C Kallen CB Seli E
J Clin Endocrinol Metab, 99:E2610-9, 2014.
Metabolomic assessment of embryo viability.
Uyar A Seli E
Semin Reprod Med, 32:141-52, 2014.
Non-invasive techniques: Embryo selection by transcriptomics, proteomics and metabolomics.
Uyar A Seli E
In: Montag M, Ed. A practical guide to select gametes and embryos. Springer/Humana Press, Berlin, German, pp 191-208, 2014.
The impact of assisted reproductive technologies on genomic imprinting and imprinting disorders.
Uyar A Seli E
Curr Opin Obstet Gynecol, 26:210-21, 2014.
Metabolism of female reproduction: Regulatory mechanisms and clinical implications.
Seli E Babayev E Collins SC Nemeth G Horvath TL
Mol Endo, 28:790-804, 2014.
Regulation of gene expression in the oocyte and early embryo: implications for transcriptomic and proteomic embryo assessment.
Kristiansson H Seli E
In: D. Gardner, D. Sakkas, E. Seli, D. Wells eds. Emerging technologies for the assessment and diagnosis of gametes and embryos. Springer/Humana Press, Berlin, Germany, pp 163-172, 2013.
mRNA-binding protein ZFP36 is expressed in atherosclerotic lesions and reduces inflammation in human aortic endothelial cells.
Zhang H Taylor WR Joseph G Sidell N Seli E Kallen CB
Arterioscl Thromb Vasc Biol, 33:1212-20 2013.
Characterization of the Gonadotropin Releasing Hormone Receptor (GnRHR) expression and activity in the Female Mouse Ovary.
Torrealday S Lalioti MD Guzeloglu-Kayisli O Seli E
Endocrinology, 154:3877-87, 2013.
Assisted reproduction in same sex couples.
Greenfeld D Seli E
In: M. Sauer ed. Principles of Oocyte and Embryo Donation. 2nd ed. Springer/Humana Press, Berlin, Germany, pp 289-301, 2013.
Cumulus and granulosa cell markers of oocyte and embryo quality.
Uyar A Torrealday S Seli E
Fertil Steril, 99:979-997, 2013.
Current trends and progress in clinical applications of oocyte cryopreservation.
Cil AP Seli E
Curr Opin Obstet Gynecol, 25:247-54, 2013.
Current practices and regulations for embryo transfer worldwide: implications on ART outcome.
Ata B Seli E
In: D. Gardner, D. Sakkas, E. Seli, D. Wells eds. Emerging technologies for the assessment and diagnosis of gametes and embryos. Springer/Humana Press, Berlin, Germany, pp 1-7, 2013.
Metabolomic profiling of oocytes and embryos using spectroscopy: potential clinical use and pitfalls.
Sakkas D Seli E
In: D. Gardner, D. Sakkas, E. Seli, D. Wells eds. Emerging technologies for the assessment and diagnosis of gametes and embryos. Springer/Humana Press, Berlin, Germany, pp 275-280, 2013.
Genetics of the germ line formation.
Ilbay O Seli E
In: C. Simon, A. Pellicer and R. Reijo-Pera, eds. Stem Cells in Reproductive Medicine. 3nd ed. Cambridge, UK, Cambridge University Press, pp 1-14, 2013.
Natural Birth-induced UCP2 in Brain Development.
Seli E Horvath T
Rev Endocr Metab Disord, 14(4):347-50, 2013.
Gamete and embryo assessment in assisted reproduction: emerging technologies
Gardner D Sakkas D Seli E Wells D
(Springer Scientific). 2013.
Embryonic poly(A) binding protein (EPAB) is required for oocyte maturation and female fertility in mouse.
Guzeloglu-Kayisli O Lalioti MD Sasson I Aydiner F Sakkas D Seli E
Biochem J, 446:47-58, 2012.
Embryo assessment strategies and their validation for clinical use: a critical analysis of methodology.
Uyar A Seli E
Curr Opin Obstet Gynecol, 24:141-50, 2012
Use of gonadotropin releasing hormone agonists in fertility preservation.
Cakmak H Seli E
In: A. Agarwal and E. Seli, eds. Fertility preservation: Emerging technologies and clinical applications. Springer/Humana Press, Berlin, Germany. pp 145-158, 2012.
Epidemiology of fertility preservation.
Murk W Seli E
In: A. Agarwal and E. Seli, eds. Fertility preservation: Emerging technologies and clinical applications. Springer/Humana Press, Berlin, Germany, pp 3-18, 2012.
Epab and Pabpc1 are differentially expressed during male germ cell development.
Ozturk S Guzeloglu-Kayisli O Demir N Lalioti MD Seli E
Reprod Sci,19:911-22, 2012.
Dynamic phosphorylation of embryonic poly(A)-binding protein (ePAB) is required for Xenopus oocyte maturation.
Friend JK Brook ML Bezirci FB Sheets MD Gray NR Seli E
Biochem J, 445:93-100, 2012.
The association between fertility clinic performance and patient volume: implications for patients’ response to physician performance.
Gong D Seli E
Fertil Steril, 98:55-62, 2012
The mRNA-binding protein Zfp36 is up-regulated by b-adrenergic stimulation and represses IL-6 production in 3T3-L1 adipocytes.
Brahma PK Murray BS Shu F Sidell N Seli E Kallen CB
Obesity, 20:40-7, 2012.
Assisted reproduction in a patient with Klippel-Trenaunay Syndrome: Management of thrombophilia and consumptive coagulopathy.
Martin JR Pels S Paidas M Seli E
J Assist Reprod Genet, 28:217-9, 2011.
The mRNA-binding protein HuR is regulated in the menstrual cycle and repressed in ectopic endometrium.
Karipcin S Altun T Kayisli UA Guzel E Kallen CB Seli E
Reprod Sci, 18:145-55, 2011
Gay men choosing parenthood through assisted reproduction: medical and psychological considerations
Greenfeld D Seli E
Fertil Steril, 95:225-9, 2011.
Receiver Operating Characteristic (ROC) analysis of Day 5 morphology grading and metabolomic Viability Scores on predicting implantation outcome.
Seli E Bruce C Botros L Henson M Roos P Judge K Sakkas D Metabolomics Study Group
J Assist Reprod Genet, 28:137-44, 2011.
Economics of assisted reproductive technologies.
Ata B Seli E
Curr Opin Obstet Gynecol, 22:183-8, 2010.
Perspectives on emerging biomarkers for non-invasive assessment of embryo viability in assisted reproduction.
Aydiner F Yetkin CE Seli E
Curr Mol Med,10:206-15, 2010.
OMICS in assisted reproduction: possibilities and pitfalls.
Seli E Robert C Sirard M-A.
Mol Hum Reprod, 16:513-30, 2010.
Ovulation Induction with clomiphene citrate.
Seli E Arici A Seli E
In: UpToDate, Rose, BD (Ed), UpToDate, Waltham, MA, 2010.
Metabolomic profiling as an adjunct to morphology for non-invasive embryo assessment in women undergoing single embryo transfer.
Seli E Vergouw CG Kato O Botros L Roos P Morita H Lambalk CB Yamashita N Sakkas D
Myoadenylate deaminase deficiency myopathy in pregnancy.
Should sperm parameters be considered in patient selection for SET?
Sakkas D El-Fakahany HM Seli E
In: J. Gerris, D. Adamson, C. Rackowsky, P. De Suttter, eds. Single embryo transfer. Cambridge, UK: Cambridge University Press, pp 241-7, 2009.
Fertility preservation in cancer survivors.
Bromer JG Seli E
In: K. D. Miller, Ed. Medical and Psychosocial Care of the Cancer Survivor. Jones & Bartlett Publishers, Sudbury, MA, pp 413-26, 2009.
Noninvasive metabolomic profiling of human embryo culture media using Raman spectroscopy predicts embryonic reproductive potential: a prospective blinded pilot
Scott RT Seli E Miller K Sakkas D Scott K Burns DH
Fertil Steril, 90: 77- 83, 2008
Identification and in vitro characterization of Follicle Stimulating Hormone (FSH) Receptor variants associated with abnormal ovarian response to FSH.
Gerasimova T Thanasoula M Zattas D Seli E Sakkas D Lalioti MD
J Clin Endocrinol Metab, 95:529-36, 2010.
Identification and characterization of human embryonic poly(A) binding protein (ePAB).
Guzeloglu-Kayisli O Pauli SA Demir H Lalioti MD Sakkas D Seli E
Mol Hum Reprod 14:581-8, 2008.
Rackow B Seli E
In: A. Arici and E. Seli, eds. Non-invasive management of gynecologic disorders. London, UK: Informa healthcare pp 125-144, 2008.
Alternative splicing of the mouse embryonic poly(A) binding protein (ePAB) RNA is regulated by an exonic splicing enhancer: a model for post-transcriptional control of gene expression in the oocyte.
Seli E Yaba A Guzeloglu-Kayisli O Lalioti MD
Mol Hum Reprod 14:393-8, 2008.
Non-invasive metabolomic profiling of embryo culture media using proton NMR correlates with reproductive potential of embryos in women undergoing in vitro fertilization.
Seli E Botros L Sakkas D Burns DH
Fertil Steril 90:2183-9, 2008.
Metabolomics and its application for non-invasive embryo assessment in IVF.
Botros L Sakkas D Seli E
Mol Hum Reprod 14:679-90, 2008.
Fertility preservation options for women with non-gynecologic cancers.
Bianchi V Johnson J Seli E
In: A. Arici and E. Seli, eds. Non-invasive management of gynecologic disorders. London, UK: Taylor and Francis pp 145-158, 2008.
Assessment of embryo viability in ART: shortcomings of current approaches and the emerging role of metabolomics.
Bromer J Seli E
Curr Opin Obstet Gynecol, 20:234-41, 2008.
Metabolomic profiling of embryo culture media to predict IVF outcome.
Bromer J Sakkas D Seli E
Expert Rev Obstet Gynecol. 3:441-447, 2008.
Evaluation of embryo quality by Metabolomics: A new strategy to aid single embryo transfer.
Sakkas D Morita H Yamashita N Kato LO Botros L Roos P Seli E
J Mammal Ova Res. 25:26-31, 2008.
Sperm DNA and embryo development.
Sakkas D Seli E
In: J. Cohen and K. Elder eds. Human preimplantation embryo selection. London, UK: Taylor and Francis pp 325-336, 2007.
Non-Invasive metabolomic profiling of human embryo culture media using Raman and near infrared spectroscopy correlates with reproductive potential of embryos in women undergoing in vitro fertilization
Seli E Sakkas D Scott RT Kwok JS Rosendahl S Burns DH
Fertil Steril 88:1350-7, 2007.
Salpingectomy increases peri-implantation endometrial HOXA10 expression in women with hydrosalpinx.
Daftary GS Kayisli UA Seli E Bukulmez O Arici A Taylor HS
Fertil Steril 87:367-72, 2007.
Molecular biology of the gamete.
Vitiello D Seli E
In: A. Pellicer and C. Simon, eds. Stem Cells in Reproductive Medicine. London, UK: Taylor and Francis pp 1-19, 2007.
Estrogen increases apoptosis in a murine atherosclerosis model.
Seli E Guzeloglu-Kayisli O Kayisli UA Kizilay G Arici A
Fertil Steril 88:1190-6, 2007.
Safety of sperm for use in ICSI.
Sakkas D Seli E Bizzaro D Manicardi GC Jakab A Huszar G
In: Diana Anderson and Martin H. Brinkworth eds. Male-Mediated Development Toxicology. Cambridge,UK: The Royal Society of Chemistry Publishing, pp. 85-93, 2007.
Selection of viable embryos and gametes by rapid, non-invasive metabolomic profiling of oxidative stress biomarkers.
Posilico JT and the Metabolomics Study Group for Reproductive Technologies. In: J. Cohen and K. Elder eds. Human preimplantation embryo selection. London, UK: Taylor and Francis pp 325-336, 2007.
Estradiol increases apoptosis in cultured human coronary artery endothelial cells (HCAEC) by up-regulating Fas expression.
Seli E Guzeloglu-Kayisli O Cakmak H Kayisli UA Selam FB Arici A.
J Clin Endocrinol Metab 91(12):4995-5001, 2006.
Stem cells and fertility: what does the future hold?
Kayisli UA Seli E
Curr Opin Obstet Gynecol 18(3):338-43, 2006.
Metazoan oocyte and early embryo development program: a progression through translation regulatory cascades.
Vasudevan S Seli E Steitz JA
Genes Dev 20:138-46, 2006. *These authors contributed equally to this work.
An embryonic poly(A)-binding protein (ePAB) is expressed in mouse oocytes and early preimplantation embryos.
Seli E Lalioti MD Flaherty SM Sakkas D Terzi N Steitz JA
Proc Natl Acad Sci USA 102:367-72, 2005.
Removal of hydrosalpinges increases endometrial leukemia inhibitory factor (LIF) expression at the time of implantation window.
Seli E Kayisli UA Cakmak H Bukulmez O Bildirici I Guzeloglu-Kayisli O Arici A
Hum Reprod 20(11):3012-7, 2005.
The significance of sperm nuclear DNA strand breaks on reproductive outcome.
Spano M Seli E Bizarro D Manicardi GC Sakkas D
Curr Opin Obstet Gynecol 17(3):255-60, 2005.
Spermatozoal nuclear determinants of reproductive outcome: implications on ART.
Seli E Sakkas D
Hum Reprod Update, 11:337-49, 2005.
Fertility preservation options for female patients with malignancies.
Seli E Tangir J
Curr Opin Obstet Gynecol 17(3):299-308, 2005.
Treatment of PCOS with metformin and other insulin sensitizing agents
Seli E Duleba A
Curr Diab Reports 4:69-75, 2004.
The extent of nuclear DNA damage in ejaculated spermatozoa impacts on blastocyst development after IVF.
Seli E Gardner DK Schoolcraft WB Moffatt O Sakkas D
Fertil Steril 82:378-83, 2004.
Immunology of endometriosis and immunotherapy.
Seli E Mahutte NG Berkkanoglu M Arici A
In: T. Tulandi and D. Redwine, eds. Endometriosis: advances and controversies. New York, NY: Marcel Dekker, Inc. pp 99-122, 2004.
Evidence based diagnosis and treatment of tubal factor infertility.
Kodaman P Arici A Seli E
Curr Opin Obstet Gynecol 16: 221-9, 2004.
The presence of abnormal spermatozoa in the ejaculate: Did apoptosis fail?
Sakkas D Seli E Manicardi GC Nijs M Ombelet W Bizzaro D
Hum Fertil 7:99-103, 2004.
Endometriosis: Interaction of immune and endocrine systems.
Seli E Arici A
Semin Reprod Med 21(2): 135-44, 2003.
Abnormal spermatozoa in the ejaculate: abortive apoptosis and faulty nuclear remodeling during spermatogenesis.
Sakkas D Seli E Bizzaro D Tarozzi N Manicardi GC
Reprod Biomed Online 7:35-9, 2003.
Modulation of the immune system by sex steroids.
Seli E Arici A
Inf Reprod Med Clin N Am 13:19-48, 2002.
Estrogen suppresses vascular monocyte chemotactic protein-1 expression during early atherogenesis.
Seli E Kayisli UA Selam B Seli E Arici A
Am J Obstet Gynecol 187:1544-9, 2002.
The reproductive system from an immunological perspective.
Seli E Mahutte NG Arici A
Immunol Allergy Clin N Am 22(3): 383-405, 2002.
Modulation of vascular immune function and atherosclerosis by reproductive hormones.
Inf Reprod Med Clin N Am 13: 233-248, 2002.
Optimizing ovulation induction in women with polycystic ovarian syndrome.
Seli E Duleba A
Curr Opin Obstet Gynecol 14 (3): 245-54, 2002.
Sex steroids and the immune system.
Seli E Arici A
Immunol Allergy Clin N Am 22(3): 407-433, 2002.
Estradiol down-regulates MCP-1 expression in human coronary artery endothelial cells.
Seli E Pehlivan T Selam B García-Velasco JA Arici A
Hum Reprod. 17:1777-82, 2002.
Proven and potential benefits of metformin in women with polycystic ovarian syndrome.
Seli E Duleba A
Hum Reprod 17(9): 2230-6, 2002.
Estrogen inhibits monocyte chemotactic protein-1 production in human coronary artery smooth muscle cells: A mechanism for its anti-atherogenic effect.
Seli E Selam B Mor G Kayisli UA Pehlivan T Arici A
Menopause 8:296-301, 2001.
Aminopeptidase N activity in human endometrium.
Seli E Senturk LM Bahtiyar OM Kayisli UA Arici A
Fertil Steril 75:1172-6, 2001.
Cytokines in the peritoneal environment.
Seli E Arici A
In: J. Hill, ed. Cytokines in human reproduction. New York, NY: Wiley-Liss pp.239-258, 2000.
Regulation of monocyte chemotactic protein-1 expression in human endometrial stromal cells by estrogen and progesterone.
Arici A Senturk LM Seli E Bahtiyar MO Kim G
Biol Reprod 61:85-90, 1999.
Regulation of monocyte chemotactic protein-1 expression in human endometrial cells by integrin-dependent cell adhesion.
García-Velasco JA Seli E Arici A
Biol Reprod 61:548-52, 1999.
Regulation of monocyte chemotactic protein-1 expression in human endometrial stromal cells by integrin-dependent cell adhesion.
García-Velasco JA Seli E Arici A
Biol Reprod. 61 :548-52, 1999.
Monocyte chemotactic protein-1 expression in human corpus luteum.
Senturk LM Seli E Gutierrez LS Mor G Zeyneloglu HB Arici A
Mol Hum Reprod 5:697-702, 1999.
Basic fibroblast growth factor: peritoneal and follicular fluid levels and its effect on the early embryonic development.
Seli E Zeyneloglu HB Senturk ML Bahtiyar OM Olive DL Arici A
Fertil Steril 69:1145-8, 1998.
Interleukin-8 induces proliferation of endometrial stromal cells: A potential autocrine growth factor.
Arici A Seli E Zeyneloglu HB Senturk LM Oral E Olive DL
J Clin Endocrinol Metab 83:1201-5, 1998.
Follicular fluid of women with endometriosis stimulates the proliferation of endometrial stromal cells.
Bahtiyar OM Seli E Oral E Senturk LM Zreik T Arici A
Hum Reprod 13:3492-5, 1998.
Interleukin-8 in the human endometrium.
Arici A Seli E Senturk LM Gutierrez LS Oral E Taylor HS
J Clin Endocrinol Metab 83:1783-7, 1998.
The peritoneal fluid levels of Interleukin-12 in women with endometriosis.
Zeyneloglu HB Senturk ML Seli E Bahtiyar OM Olive DL Arici A
American J Reprod Immunol 39:152-6, 1998.
The role of monocyte chemotactic protein-1 in intraperitoneal adhesion formation.
Zeyneloglu HB Senturk LM Seli E Oral E Olive DL Arici A
Hum Reprod 13:1194-9, 1998.
The effect of monocyte chemotactic protein-1 in intraperitoneal adhesion formation in a mice model.
Zeyneloglu HB Seli E Senturk LM Gutierrez LS Olive DL Arici A
Am J Obstet Gynecol 179:438-43, 1998.
Midtrimester urine human chorionic gonadotropin b-subunit core fragment levels and the subsequent development of preeclampsia.
Bahado-Singh RO Oz U Isozaki T Seli E Kovanci E Hsu CD Cole L
Am J Obstet Gynecol 179:738-41, 1998.
Growth-regulated a expression in human preovulatory follicles and ovarian cells.
Oral E Seli E Bahtiyar MO Jones EE Arici A
Am J Reprod Immunol 38:19-25, 1997.
Leukemia inhibitory factor expression in human follicular fluid and ovarian cells.
Arici A Oral E Bahtiyar MO Engin O Seli E Jones EE
Hum Reprod. 1997 Jun;12(6):1233-9.
Growth-regulated gene a expression in human peritoneal environment with endometriosis.
Oral E Seli E Bahtiyar MO Olive DL Arici A
Obstet Gynecol 88:1050-56, 1996.