Marie D. Werner, M.D.

Reproductive Endocrinologist at RMA of New Jersey

RMA New Jersey

Biography

Marie D. Werner, MD, FACOG, HCLD/ALD (ABB) is an attending physician at Reproductive Medicine Associates of New Jersey. Dr. Werner graduated from Boston College with a focus in History and Biochemistry. She then went on to the University of Medicine and Dentistry: New Jersey Medical School where she received her medical degree and was awarded the gold humanism in medicine award. She completed her residency training in Obstetrics and Gynecology at New York University where she was elected as the administrative chief resident. Dr. Werner completed her Reproductive Endocrinology and Infertility fellowship training at Reproductive Medicine Associates of New Jersey (RMANJ) in the Rutgers Robert Wood Johnson fellowship program

Dr. Marie Werner is a board certified Obstetrician Gynecologist, Reproductive endocrinologist and infertility specialist, and board certified High Complexity Lab Director/Andrology Laboratory director in the fields of embryology and andrology. She is the Associate Director for the Reproductive Endocrinology and Infertility Fellowship program at Reproductive Medicine Associates of NJ where she teaches fellows and develops clinical education and research interests.
Dr. Werner received the SRBT Clinical Science Award and the Corporate Member Council In-Training Grant from the American Society for Reproductive Medicine for her research contributions. She serves as an Ad Hoc Reviewer for Fertility and Sterility. Her research interests include ART laboratory science, assessment of embryonic competence and autoimmune disorders and pregnancy.

BS	Boston College (2004)
MD	UMDNJ: New Jersey Medical School (2008)
Residency	New York University School of Medicine (2012)
Fellowship	Rutgers University, Reproductive Medicine Associates of New Jersey (2015)

Honors and recognition

American Society for Reproductive Medicine SRBT Clinical Science Award	2016
American Society for Reproductive Medicine CMC In-Training Travel Award	2015
Midwest Reproductive Symposium Travel Grant	2015
Midwest Reproductive Symposium Southbound Train Grant Award	2014
NYU Chief Resident Teaching Award	2012
NYU Best Senior Resident Teaching Award	2012
Gold Humanism Honor Society	2007
Young Investigators Travel Grant: American Thyroid Association	2006
Alpha Phi Delta Scholarship	2004
National Society of Collegiate Scholars	2002-2004
Phi Alpha Theta, Honors Program in History	2002-2004
Golden Key National Honors Society	2002-2004
National Dean’s List	2002-2004
Boston College Dean’s List	2001-2004

Publications

Sperm DNA fragmentation on the day of fertilization is not associated with embryologic or clinical outcomes after IVF/ICSI.
Green KA Patounakis G Dougherty MP Werner MD Scott RT Franasiak JM
J Assist Reprod Genet. 2019 Nov 21. doi: 10.1007/s10815-019-01632-5. [Epub ahead of print]

Mosaic embryos present a challenging clinical decision.
Osman EK Werner MD
Fertil Steril. 2019 Jan;111(1):52-53. doi: 10.1016/j.fertnstert.2018.10.032. No abstract available.

Preimplantation genetic testing for aneuploidy is cost-effective, shortens treatment time, and reduces the risk of failed embryo transfer and clinical miscarriage.
Neal SA Morin SJ Franasiak JM Goodman L Juneau CR Forman EJ Werner MD Scott RT
Fertil Steril, 110(5):896-904, 2018.

Quest for a less invasive approach to preimplantation genetic testing remains ongoing
Neal SA Werner MD
Fertil Steril, 110(5):854-856, 2018.

Cumulus cell transcriptome profiling is not predictive of live birth after in vitro fertilization: a paired analysis of euploid sibling blastocysts.
Green KA Franasiak JM Werner MD Tao X Landis JN Scott RT Treff NR
Fertil Steril, 109(3):460-466, 2018.

Preclinical Validation of a Targeted Next Generation Sequencing-based Comprehensive Chromosome Screening Methodology in Human Blastocysts.
Zimmerman RS Tao X Marin D Werner MD Hong K Lonczak A Landis J Taylor D Zhan Y Scott RT Treff NR
Mol Hum Reprod, 24:37-45, 2018

The impact of contemporary preimplantation genetic screening and diagnosis on the detection of aneuploidy and inherited genetic diseases.
Neal SA Werner MD
Birth Defects Res, 110(8):644-647, 2018.

Cumulus cell transcriptome profiling is not predictive of live birth after in vitro fertilization: a paired analysis of euploid sibling blastocysts.
Green KA Franasiak JM Werner MD Tao X Landis JN Scott RT Treff NR
Fertil Steril, 109(3):460-466, 2018.

Patients with endometriosis have aneuploidy rates equivalent to their age-matched peers in the IVF population
Juneau C Kraus E Werner MD Franasiak JM Morin SJ Patounakis G Molinaro T de Ziegler D Scott RT
Fertil Steril, 108: 284-288, 2017.

Patients with endometriosis have aneuploidy rates equivalent to their age-matched peers in the in vitro fertilization population.
Juneau C Kraus E Werner MD Franasiak JM Morin SJ Patounakis G Molinaro T De Ziegler D Scott RT
Fertil Steril, 108(2):284-288, 2017.

High relative deoxyribonucleic acid content of trophectoderm biopsy adversely affects pregnancy outcomes.
Neal SA Franasiak JM Forman EJ Werner MD Morin SJ Tao X Treff NR Scott RT
Fertil Steril, 107(3):731-736, 2017.

Cumulus cell transcriptome profiling is not predictive of live birth after in vitro fertilization: a paired analysis of euploid sibling blastocysts.
Greene K Treff NR Franasiak JM Werner MD Tao X Landis JN Scott RT
Fertil Steril. In Press. 2017.

Patients with endometriosis have aneuploidy rates equivalent to their age-matched peers in the in vitro fertilization population.
Juneau C Kraus E Werner MD Franasiak JM Morin SJ Patounakis G Molinaro T De Ziegler D Scott RT
Fertil Steril. 2017 Jun 23. pii: S0015-0282(17)30421-1. doi: 10.1016/j.fertnstert.2017.05.038. [Epub ahead of print]

High relative deoxyribonucleic acid of trophectoderm biopsy adversely affects pregnancy outcomes
Neal S Franasiak JM Forman E Werner MD Morin SJ Tao X Treff N Scott RT
Fertil Steril, 107:731-736

FMR1 gene CGG repeat variation within the normal range is not predictive of ovarian response in IVF cycles.
Morin SJ Tiegs AW Franasiak JM Juneau CR Hong KH Werner MD Zhan Y Landis J Scott RT
Reprod Biomed Online 32(5):496–502, 2016

Expanded carrier screening in an infertile population: how often is clinical decision making affected?
Franasiak JM Olcha M Bergh PA Hong KH Forman EJ Werner MD
Genet Med Off J Am Coll Med Genet 2016.

Sequential versus Monophasic Media Impact Trial (SuMMIT): a paired randomized controlled trial comparing a sequential media system to a monophasic medium.
Werner MD Hong KH Franasiak JM Forman EJ Reda CV Molinaro T
Fertil Steril 2016.

Free vitamin D does not vary through the follicular phase of the menstrual cycle.
Franasiak JM Wang X Molinaro T Green K Sun W Werner MD Juneau CR Scott RT
Endocrine, 53(1):322-6, 2016.

Free vitamin D does not vary through the proliferative phase of the menstrual cycle.
Franasiak JM Wang X Sun W Molinaro T Green K Werner MD Juneau C Morin SJ Scott RT
Endocrine 53:322-6, 2016.

Dehydroepiandrosterone (DHEA) supplementation results in supraphysiologic DHEA-S serum levels and progesterone assay interference that may impact clinical management in IVF.
Franasiak JM Werner MD Juneau CR Scott RT Forman EJ
J Assist Reprod Genet 33:387-91, 2016

Endometrial microbiome at the time of embryo transfer: next generation sequencing of 16S ribosomal subunit.
Franasiak JM Werner MD Juneau C Tao X Landis J Zhang Y Treff NR Scott RT
J Assist Reprod Genet, 33:129-36, 2016.

Investigating the optimal preconception TSH range for patients undergoing IVF when controlling for embryo quality.
Green KA Werner MD Franasiak JM Juneau CR Hong KH Scott RT
J Assist Reprod Genet 2015;32(10):1469–76.

24-chromosome PCR for aneuploidy screening.
Werner MD Scott RT
Curr Opin Obstet Gynecol. 2015.

Endometrial disruption does not improve implantation in patients who have failed the transfer of euploid blastocysts.
Werner MD Forman EJ Hong KH Franasiak JM Bergh PA Scott RT
J Assist Reprod Genet 2015.

Blastocyst transfer is not associated with increased rates of monozygotic twins when controlling for embryo cohort quality.
Franasiak JM Dondik Y Molinaro T Hong KH Forman EJ Werner MD
Fertil Steril 2015;103(1):95–100.

Vitamin D levels do not affect IVF outcomes following the transfer of euploid blastocysts.
Franasiak JM Molinaro T Dubell EK Scott KL Ruiz AR Forman EJ Werner MD
Am J Obstet Gynecol 2015;212(3):315.e1–6.

Endometrial Microbiome at the Time of Embryo Transfer: Next Generation Sequencing of the 16s Ribosomal Subunit.
Franasiak JM Werner MD Juneau C Tao X Landis J Zhan Y Treff N Scott RT
J Assist Reprod Genet 33:129-36, 2015.

Aneuploidy across individual chromosomes at the embryonic level in trophectoderm biopsies: changes with patient age and chromosome structure.
Franasiak JM Forman EJ Hong KH Werner MD Upham KM Treff NR
Assist Reprod Genet 2014.

Endometrial infusion of human chorionic gonadotropin at the time of blastocyst embryo transfer does not impact clinical outcomes: a randomized, double-blind, placebo-controlled trial.
Hong KH Forman EJ Werner MD Upham KM Gumeny CL Winslow AD
Fertil Steril 2014;102(6):1591–5.e2.

Defining the “sweet spot” for administered luteinizing hormone-to-follicle-stimulating hormone gonadotropin ratios during ovarian stimulation to protect against a clinically significant late follicula
Werner MD Forman EJ Hong KH Franasiak JM Molinaro T Scott RT
Fertil Steril 2014;102(5):1312–7.

Embryology training for Reproductive Endocrine fellows in the clinical human embryology laboratory.
Scott RT Hong KH Werner MD Forman EJ Ruiz A Cheng MC
J Assist Reprod Genet 2014;31(4):385–91.

The nature of aneuploidy with increasing age of the female partner: a review of 15,169 consecutive trophectoderm biopsies evaluated with comprehensive chromosomal screening.
Franasiak JM Forman EJ Hong KH Werner MD Upham KM Treff NR
Fertil Steril 2014;101(3):656–663.e1.

Clinically recognizable error rate after the transfer of comprehensive chromosomal screened euploid embryos is low.
Werner MD Leondires MP Schoolcraft WB Miller BT Copperman AB Robins ED
Fertil Steril 2014;102(6):1613–8.

Endometrial infusion of human chorionic gonadotropin at the time of blastocyst embryo transfer does not impact clinical outcomes: a randomized double-blind, placebo controlled trial.
Hong KH Werner MD Upham K Kim T Winslow A EJ Forman Scott RT
Fertil Steril, 102:1591-1595, 2014.

Embryology Training for Reproductive Endocrine Fellows in the Clinical Human Embryology Laboratory
Scott RT Hong KH Werner MD Forman EJ Upham K Ruiz A Zhao T Cheng M
J Assist Reprod Genet, 31(4):385-91, 2014.

The Nature of Aneuploidy with Increasing Age of the Female Partner: A Review of 15,169 Trophectoderm Biopsies Undergoing Comprehensive Chromosomal Screening.
Franasiak JM Forman EJ Hong KH Werner MD Upham K Treff NR Scott RT
Fertil Steril, 101:656-663, 2014.

Extended culture and the risk of preterm delivery in singletons: confounding by indication?
Forman EJ Werner MD Scott RT
Hum Reprod. Jul 2013; 28 (7): 2021.

Characteristics of chromosomal abnormalities diagnosed after spontaneous abortions in an infertile population.
Werner MD Reh A Grifo J Perle MA
J Assist Reprod Genet. May 2012. J Assist Reprod Genet. August 2012; 29 (8); 817-20.

Laboratory evaluation in oocyte cryopreservation suggests retrieved oocytes are comparable whether frozen for medical indications, deferred reproduction, or oocyte donation.
Werner MD Reh A Labella P Noyes N
J Assist Reprod Genet. Nov 2010; 27 (11); 613-7.

Hanson BM Kim G Osman EK Tiegs AW Neal SA Werner MD Scott RT P-228 THE IMPACT OF OVARIAN RESPONSE ON CLINICAL PREGNANCY AND DELIVERY RATES IN AN OOCYTE DONOR POPULATION. Presented at 75th American Society of Reproductive Medicine Scientific Congress, Philadelphia, PA. USA, 14-16 October 2019

Neal SA Morin SJ Werner MD Gueye N Pirtea P Patounakis G Scott RT Goodman LR O-214 THREE-DIMENSIONAL ULTRASOUND DIAGNOSIS OF ADENOMYSIS IS NOT ASSOCIATED WITH DIMINISHED LIVE BIRTH FOLLOWING SINGLE THAWED EUPLOID BLASTOCYST TRANSFER: A PROSPECTIVE COHORT STUDY. Presented at 75th American Society of Reproductive Medicine Scientific Congress, Philadelphia, PA. USA, 14-16 October 2019

Klimczak AM Whitehead CR Neal SA Tiegs AW Osman EK Hanson BM Werner MD Kim G Franasiak JM Scott RT O-41 NON-INVASIVE PRENATAL TESTING HAS ALTERED POSITIVE PREDICTIVE VALUE FOLLOWING TRANSFER OF A EUPLOID BLASTOCYST. Presented at 75th American Society of Reproductive Medicine Scientific Congress, Philadelphia, PA. USA, 14-16 October 2019

Neal A Goodman LR Morin SJ Werner MD Gueye N Tiegs W Pirtea P Scott RT Only patients with obvious adenomyosis on three-dimensional ultrasound (3d us) are at increased risk of clinical loss following frozen embryo transfer. Presented at the 74th Scientific Congress & Expo of the American Society for Reproductive Medicine, Denver, CO, USA, October 6-10, 2018

Neal A Goodman LR Morin SJ Werner MD Gueye N Tiegs W Pirtea P Scott RT T-shaped uterine cavity morphology as assessed by three-dimensional ultrasound (3d us) is associated with lower sustained implantation rates and higher clinical loss rates following frozen embryo. Presented at the 74th Scientific Congress & Expo of the American Society for Reproductive Medicine, Denver, CO, USA, October 6-10, 2018

Dolitsky N Neal SA Olcha M Hong K Werner MD Morin SJ Tiegs W Sun L Scott RT Initial serum human chorionic gonadotropin levels predict live birth outcomes following frozen embryo transfer with and without preimplantation genetic testing for aneuploidy (pgt-a). Presented at the 74th Scientific Congress & Expo of the American Society for Reproductive Medicine, Denver, CO, USA, October 6-10, 2018

Parker PB Morin SJ Neal SA Tiegs W Werner MD Inner cell mass and trophectoderm morphology impact the likelihood of achieving sustained implantation among expanded, euploid blastocysts. Presented at the 74th Scientific Congress & Expo of the American Society for Reproductive Medicine, Denver, CO, USA, October 6-10, 2018

Reig A Morin SJ Goodman LR Franasiak JM Molinaro T Scott RT Werner MD Discordant follicle-stimulating hormone and anti-mullerian hormone and the prediction of euploid blastocyst yield. Presented at the 74th Scientific Congress & Expo of the American Society for Reproductive Medicine, Denver, CO, USA, October 6-10, 2018

Franasiak JM Hong KH Werner MD Juneau CR Morin SJ Neal SA Molinaro T Scott RT Preimplantation genetic screening (PGS) in low responders shortens time to pregnancy: a randomized controlled trial. Presented at the 73rd annual meeting of the American Society of Reproductive Medicine, San Antonio, Texas, October 28-November 1,2017

Marie D. Werner, M.D.

Biography

Education and Training

Honors and recognition

Publications

Presentations