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The first mitotic division: a perilous bridge connecting the zygote and the early embryo
Giovanni Coticchio, Danilo Cimadomo, Greta Chiara Cermisoni, Laura Rienzi, Enrico Papaleo, Filippo Maria Ubaldi, Andrea Borini, Lucia De Santis
Human Reproduction, Volume 38, Issue 6, June 2023, Pages 1019–1027, https://doi.org/10.1093/humrep/dead067. 2023 doi:
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Should patients be screened for chronic endometritis before assisted reproductive technology?
Ettore Cicinelli, Dana B McQueen, Bridget Huepfel, Amerigo Vitagliano, Inmaculada Moreno, Carlos Simon, Paul Pirtea, Richard T Scott Jr, Marina Bellavia, Dominique Ziegler
Fertility and Sterility 29 September 2022, Volume 118, Issue 4, October 2022, Pages 639-652. 2022 doi:
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The cyto-protective effects of LH on ovarian reserve and female fertility during exposure to gonadotoxic alkylating agents in an adult mouse model.
Del Castillo LM, Buigues A, Rossi V, Soriano MJ, Martinez J, De Felici M, Lamsira HK, Di Rella F, Klinger FG, Pellicer A, Herraiz S
Hum Reprod. 2021 doi:
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Genome editing reveals a role for OCT4 in human embryogenesis.
Fogarty, N, McCarthy, A, Snijders, KE, Powell, BE, Kubikova, N, Blakeley, P, Lea, R, Elder, K, Wamaitha, S, Daesik, K, Maciulyte, V, Kleinjung, J, Kim, J, Wells, D, Vallier, L, Bertero, A, Turner, J, Elder, K,
Nature. 2017 doi:
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Mitochondrial DNA quantification as a tool for embryo viability assessment: retrospective analysis of data from single euploid blastocyst transfers.
Ravichandran, K, McCaffrey, C, Grifo, J, Morales, A, Perloe, M, Munne, S, Wells, D, Fragouli, E,
Hum Reprod. 2017 doi:
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Supplementation with progestogens in the first trimester of pregnancy to prevent miscarriage in women with unexplained recurrent miscarriage: a systematic review and meta-analysis of randomized, controlled trials.
Saccone, G, Schoen, C, Franasiak, J M, Scott, R T, Berghella, V,
Fertil Steril. 2017 doi:
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Survey of Fertility Preservation Options Available to Patients With Cancer Around the Globe. J Glob Oncol. 4, pp. 1 - 16. 28/06/2017.
Rashedi, AS, de, Roo, SF, Ataman, LM, Edmonds, ME, Silva, AA, Scarella, A, Horbaczewska, A, Anazodo, A, Arvas, A, Ramalho, de, Carvalho, B, Sartorio, C, Beerendonk, CCM, Diaz-Garcia, C, Anazodo, A,
2017 doi:
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A randomized and blinded comparison of qpcr and NGS based detection of aneuploidy in a cell line mixture model of blastocyst biopsy mosaicism.
Goodrich, D, Tao, X, Bohrer, C, Lonczak, A, Xing, T, Zimmerman, R, Zhan, Y, Scott, R T, Treff, NR, Scott, R T,
Hum Reprod. 2016 doi:
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Cancer risk in first- and second-degree relatives of men with poor semen quality.
Anderson, RE, Hanson, H, Patel, D, Johnstone, E, Aston, K, Carrell, D, Lowrance, W, Smith, K, Hotaling, J M, Smith, K,
Fertil Steril. 2016 doi:
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Cardiovascular Autonomic Neuropathy, Sexual Dysfunction, and Urinary Incontinence in Women With Type 1 Diabetes.
Hotaling, J M, Sarma, AV, Patel, DP, Braffett, BH, Cleary, PA, Feldman, E, Herman, WH, Martin, CL, Jacobson, AM, Wessells, H, Pop-Busui, R, Martin, CL,
Diabetes Care. 2016 doi:
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Causes and estimated incidences of sex-chromosome misdiagnosis in preimplantation genetic diagnosis of aneuploidy.
Ravichandran, K, Guzman, L, Escudero, T, Zheng, X, Colls, P, Jordan, A, Cohen, J, Wells, D, Munne, S, Wells, D,
RBM Online. 2016 doi:
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Decreased fecundity and sperm DNA methylation patterns.
Jenkins, TG, Aston, KI, Meyer, TD, Hotaling, J M, Shamsi, MB, Johnstone, EB, Cox, KJ, Stanford, JB, Porucznik, CA, Carrell, DT,
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Development and validation of concurrent preimplantation genetic diagnosis for single gene disorders and comprehensive chromosomal aneuploidy screening without whole-genome amplification.
Zimmerman, RS, Jalas, C, Tao, X, Fedick, AM, Kim, J, Pepe, RJ, Northrop, LE, Scott, R T, Treff, NR, , Scott, R T,
Fertil Steril. 2016 doi:
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Embryonic aneuploidy does not differ among genetic ancestry according to continental origin as determined by ancestry informative markers.
Franasiak, J M, Olcha, M, Shastri, S, Molinaro, T A, Congdon, H, Treff, NR, Scott, R T,
Hum Reprod. 2016 doi:
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FMR1 Gene CGG repeat number variation within the normal range is not predictive of ovarian response in IVF cycles.
Morin, S J, Tiegs, A, Franasiak, J M, Juneau, CR, Scott, R T,
RBM Online. 2016 doi:
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Following declining human chorionic gonadotropin values in pregnancies of unknown location: when is it safe to stop?
Cameron, KE, Senapati, S, Sammel, MD, Chung, K, Takacs, P, Molinaro, T A, Barnhart, KT,
Fertil Steril. 2016 doi:
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Free vitamin D does not vary through the follicular phase of the menstrual cycle.
Franasiak, J M, Wang, X, Molinaro, T A, Green, K, Sun, W, Werner, M D, Juneau, CR, Scott, R T,
Endocrine. 2016 doi:
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Free vitamin D does not vary through the proliferative phase of the menstrual cycle.
Franasiak, J M, Wang, X, Sun, W, Molinaro, T A, Green, K, Werner, M D, Juneau, C, Morin, S J, Scott, R T, Morin, S J,
Endocrine. 2016 doi:
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Frozen-thawed embryo transfers in natural cycles with spontaneous or induced ovulation: the search for the best protocol continues
Montagut, M, Santos-Ribeiro, S, De, Vos, M, Polyzos, NP, Drakopoulos, P, Mackens, S, van, de, Vijver, A, Verheyen, G, Tournaye, H, Blockeel, C,
Hum Reprod. 2016 doi:
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Glycemic control and urinary tract infections in women with Type-1 Diabetes: Results from the DCCT/EDIC.
Lenherr, SM, Clemens, JQ, Braffett, BH, Cleary, PA, Dunn, RL, Hotaling, J M, Jacobson, AM, Kim, C, Herman, W, Brown, JS, Wessells, H, Sarma, AV, DCCT/EDIC, Research, Group, Kim, C,
J Urol. 2016 doi:
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Investigation of sperm telomere length as a potential marker of paternal genome integrity and semen quality.
Cariati, F, Jaroudi, S, Alfarawati, S, Raberi, A, Alviggi, C, Pivonello, R, Wells, D,
RBM Online. 2016 doi:
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Is the effect of premature elevated progesterone augmented by human chorionic gonadotropin versus gonadotropin-releasing hormone agonist trigger?
Connell, MT, Patounakis, G, Healy, MW, DeCherney, AH, Devine, K, Widra, E, Levy, MJ, Hill, MJ,
Fertil Steril. 2016 doi:
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Next Generation Sequencing Based Comprehensive Chromosome Screening in Mouse Polar Bodies, Oocytes, and Embryos.
Treff, NR, Krisher, R, Tao, X, Garnsey, H, Bohrer, C, Silva, E, Landis, J, Taylor, D, Scott, R T, Woodruff, TK, Duncan, FE, Taylor, D,
Biol Reprod. 2016 doi:
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Non-steroidal anti-inflammatory drug (NSAID) use is not associated with erectile dysfunction risk: results from the Prostate Cancer Prevention Trial.
Patel, DP, Schenk, JM, Darke, A, Myers, JB, Brant, WO, Hotaling, J M,
BJU Int. 2016 doi:
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Subfertility increases risk of testicular cancer: evidence from population-based semen samples.
Hanson, HA, Anderson, RE, Aston, KI, Carrell, DT, Smith, KR, Hotaling, J M,
Fertil Steril. 2016 doi:
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Teratozoospermia and asthenozoospermia are associated with specific epigenetic signatures.
Jenkins, TG, Aston, KI, Hotaling, J M, Shamsi, MB, Simon, L, Carrell, DT,
Andrology. 2016 doi:
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Towards clinical application of pronuclear transfer to prevent mitochondrial DNA disease.
Hyslop, LA, Blakeley, P, Craven, L, Richardson, J, Fogarty, NM, Fragouli, E, Lamb, M, Wamaitha, SE, Prathalingam, N, Zhang, Q, O'Keefe, H, Takeda, Y, Arizzi, L, Alfarawati, S, Tuppen, HA, Irving, L, Kalleas, D, Wamaitha, SE, Wells, D, Murdoch, AP, Turnbull, DM, Niakan, KK, Herbert, M,
Nature. 2016 doi:
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Why do euploid embryos miscarry? A case-control study comparing the rate of aneuploidy within presumed euploid embryos that resulted in miscarriage or live birth using next-generation sequencing.
Maxwell, SM, Colls, P, Hodes-Wertz, B, McCulloh, DH, McCaffrey, C, Wells, D, Munne, S, Grifo, J,
Fertil Steril. 2016 doi:
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Cardiovascular autonomic neuropathy, erectile dysfunction and lower urinary tract symptoms in men with type 1 diabetes: findings from the DCCT/EDIC.
Pop-Busui, R, Hotaling, J M, Braffett, BH, Cleary, P, Dunn, RL, Martin, C, Jacobson, A, Wessells, H, Sarma, A, Wessells, H,
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High-grade renal injuries are often isolated in sports-related trauma.
Patel, DP, Redshaw, JD, Breyer, B, Smith, T, Erickson, B, Majercik, S, Gaither, T, Craig, J, Gardner, S, Presson, A, Zhang, C, Hotaling, J M, Brant, WO, Myers, J,
Injury. 2015 doi:
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Karyomapping allows preimplantation genetic diagnosis of a de-novo deletion undetectable using conventional PGD technology.
Gimenez, C, Sarasa, J, Arjona, C, Vilamajo, E, Martinez-Pasarell, O, Wheeler, K, Valls, G, Garcia-Guixe, E, Wells, D, Garcia-Guixe, E,
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Live births following Karyomapping of human blastocysts: experience from clinical application of the method.
Konstantinidis, M, Prates, R, Goodall, N, Fischer, J, Tecson, V, Lemma, T, Chua, B, Jordan, A, Armenti, E, Wells, D, Munne, S, Jordan, A,
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Micro-electrophoresis: a noninvasive method of sperm selection based on membrane charge.
Simon, L, Murphy, K, Aston, K, Emery, B, Hotaling, J M, Carrell, D,
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Routine use of next-generation sequencing for preimplantation genetic diagnosis of blastomeres obtained from embryos on day 3 in fresh in~vitro fertilization cycles.
Ukaszuk K, Pukszta, S, Wells, D, Cybulska, C, Liss, J, P?ociennik, ?, Kuczy?ski, W, Zabielska, J,
Fertil Steril. 2015 doi:
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s endometrial receptivity transcriptomics affected in women with endometriosis? A pilot study.
Garcia-Velasco, J A, Fassbender, A, Ruiz, Alonso, M, Blesa, D, D'Hooghe, T, Simon, C,
RBM Online. 2015 doi:
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Sperm concentration is poorly associated with hypoandrogenism in infertile men.
Patel, DP, Brant, WO, Myers, JB, Zhang, C, Presson, A, Johnstone, E, Dorais, J, Aston, KI, Carrell, D, Hotaling, J M,
Urology. 2015 doi:
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Targeted Germline Modifications in Rats Using CRISPR/Cas9 and Spermatogonial Stem Cells.
Chapman, K, Medrano, G, Jaichander, P, Chaudhary, Waits, A, Nobrega, M, Hotaling, J M, Ober, C, Hamra, F, Ober, C,
Cell Rep. 2015 doi:
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The use of morphokinetics as a predictor of implantation: a multicentric study to define and validate an algorithm for embryo selection.
Basile, N, Vime, P, Florensa, M, Aparicio, Ruiz, B, Garcia-Velasco, J A, Remohi, J, Meseguer, M,
Hum Reprod. 2015 doi:
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Validation of next-generation sequencing for comprehensive chromosome screening of embryos.
Kung, A, Munne, S, Bankowski, B, Coates, A, Wells, D,
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Clinical utilization of a rapid low-pass whole genome sequencing technique for the diagnosis of aneuploidy in human embryos prior to implantation.
Wells, D, Kaur, K, Grifo, J, Glassner, M, Taylor, JC, Fragouli, E, Munne, S,
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Endometrial CXCL13 expression is cycle regulated in humans and aberrantly expressed in humans and macaques with endometriosis
Franasiak, J M, Burns, K, Slayden, O, Yuan, L, Fritz, M, Korach, K, Lessey, BA, Young, SL,
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Genome-wide karyomapping accurately identifies the inheritance of single-gene defects in human preimplantation embryos in vitro.
Natesan, SA, Bladon, AJ, Coskun, S, Qubbaj, W, Prates, R, Munne, S, Coonen, E, Dreesen, JC, Stevens, SJ, Paulussen, AD, Stock-Myer, SE, Wilton, LJ, Jaroudi, S, Wells, D, Brown, AP, Handyside, AH, Dreesen, JC,
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Increasing the probability of selecting chromosomally normal embryos by time-lapse morphokinetic analysis.
Basile, N, Bronet, F, Nogales, MC, Martinez, E, Ariza, M, Agudo, D, Florensa, M, Riqueros, M, Meseguer, M, Riqueros, M,
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Live birth after PGD with confirmation by a comprehensive approach (karyomapping) for simultaneous detection of monogenic and chromosomal disorders.
Natesan, SA, Handyside, AH, Thornhill, AR, Ottolini, CS, Sage, K, Summers, MC, Konstantinidis, M, Wells, D, Griffin, DK,
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Ko, EM, Walter, P, Clark, L, Jackson, A, Franasiak, J M, Bolac, C, Havrilesky, L, Alvarez, Secord, A, Moore, D, Gehrig, P, Bae-Jump, VL,
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Non-invasive prediction of embryonic sex in cattle by metabolomic analysis of in vitro culture medium with Fourier transfrom infrared spectroscopy.
Muñoz, M, Uyar, A, Correia, E, Diez, C, Fernandez, A, Caamaño, JN, Trigal, B, Carrocera, S, Seli, E, Gomez, E,
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Persistence of urothelial carcinoma of the bladder risk among former smokers: results from a contemporary, prospective cohort study.
Welty, C, Wright, J, Hotaling, J M, Bhatti, P, Porter, M, White, E,
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Simple circumcision device: proof of concept for a single-visit, adjustable device to facilitate safe adult male circumcision.
Kadlec, AO, Ohlander, S, Hotaling, J M, Hannick, J, Niederberger, C, Turk, TM,
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Simultaneous assessment of aneuploidy, polymorphisms, and mitochondrial DNA content in human polar bodies and embryos with the use of a novel microarray platform.
Konstantinidis, M, Alfarawati, S, Hurd, D, Paolucci, M, Shovelton, J, Fragouli, E, Wells, D,
Fertil Steril. 2014 doi:
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Succesful twin delivery following transmyometrial embryo transfer in a patient with a false uterine cavity.
Muñoz, M, Galindo, N, Perez, I-Cano, Cruz, M, Garcia-Velasco, J A,
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The nature of aneuploidy with increasing age of the female partner: a review of 15,169 consecutive trophectoderm biopsies evaluated with comprehensive chromosomal screening.
Franasiak, J M, Forman, EJ, Hong, KH, Werner, M D, Upham, KM, Treff, NR,
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Uniparental disomy in the human blastocyst is exceedingly rare.
Gueye, N, Devkota, B, Taylor, D, Pfundt, R, Scott, R T, Tref, N,
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Additive effect of factors related to assisted conception on the reduction of maternal serum pregnancy-associated plasma protein A concentrations and the increased false-positive rates in first-trimester Down syndrome screening.
Bellver, J, Casanova, C, Garrido, N, Lara, C, Remohi, J, Pellicer, A, Serra, V,
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Blastocyst biopsy with comprehensive chromosome screening and fresh embryo transfer significantly increases IVF implantation and delivery rates: a randomized controlled trial.
Scott, R T, Ferry, KM, Forman, EJ, Hong, KH, Scott, KL, Taylor, D, Tao, X, Treff, NR,
Fertil Steril. 2013 doi:
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Cleavage stage biopsy significantly impairs human embryonic implantation potential while blastocyst biopsy does not: a randomized and paired clinical trial.
Scott, R T, Ferry, KM, Forman, EJ, Zhao, T, Treff, NR,
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Comprehensive chromosome screening alters traditional morphology-based embryo selection: a prospective study of 100 consecutive cycles of planned fresh euploid blastocyst transfer.
Forman, EJ, Upham, KM, Cheng, MZ, Zhao, T, Hong, KH, Treff, NR, Scott, R T,
Fertil Steril. 2013 doi:
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Embryos whose polar bodies contain isolated reciprocal chromosome aneuploidy are almost always euploid.
Forman, EJ, Treff, NR, Stevens, JM, Garnsey, HM, Katz-Jaffe, MG, Scott, R T, Schoolcraft, WB,
Hum Reprod. 2013 doi:
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2013 |
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Endometrial integrin expression in women with recurrent implantation failure after IVF; relationship to pregnancy outcome
Coughlan, C, Sinagra, M, Ledger, W, Li, T, Laird, SM,
Fertil Steril. 2013 doi:
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2013 |
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2013 |
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Evaluation of targeted next-generation sequencing based preimplantation genetic diagnosis of monogenic disease.
Treff, NR, Fedick, A, Tao, X, Devkota, B, Taylor, D, Scott, R T,
Fertil Steril. 2013 doi:
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2013 |
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2013 |
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In vitro fertilization outcome in women with unoperated bilateral endometriomas
Benaglia, L, Bermejo, A, Somigliana, E, Faulisi, S, Ragni, G, Fedele, L, Garcia-Velasco, J A,
Fertil Steril. 2013 doi:
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Obesity reduces uterine receptivity: clinical experience from 9,587 first cycles of ovum donation with normal weight donors.
Bellver, J, Pellicer, A, Garcia-Velasco, J A, Ballesteros, A, Remohi, J, Meseguer, M,
Fertil Steril. 2013 doi:
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2013 |
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2013 |
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Risk factors for renal cell carcinoma in the VITAL study.
Macleod, L, Hotaling, J M, Wright, JL, Gore, JL, Harper, J, White, E,
Urol Oncol. 2013 doi:
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The complex triad of obesity, race and diabetes in Type I and Type II endometrial cancers: examining their distribution and associations with outcomes.
Ko, EM, Walter, P, Clark, L, Jackson, A, Franasiak, J M, Havrilesky, L, Alvarez, Secord, A, Moore, D, Gehrig, P, Bae-Jump, VLMoore, D,
Gynecol Oncol. 2013 doi:
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2013 |
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The international agreement study on the diagnosis of the septate uterus at office hysteroscopy in infertile patients
Smit, JG, Kasius, JC, Eijkemans, M, Veersema, S, Fatemi, HM, Santbrink, van, E, Campo, R, Broekmans, F,
Fertil Steril. 2013 doi:
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2013 |
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The origin and impact of embryonic aneuploidy.
Fragouli, E, Alfarawati, S, Spath, K, Jaroudi, S, Sarasa, J, Enciso, M, Wells, D,
Hum Genet. 2013 doi:
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2013 |
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2013 |
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Validity and reliability of a smartphone application for the assessment of penile deformity in Peyronie's disease.
Hsi, RS, Hotaling, J M, Hartzler, AL, Holt, SK, Walsh, TJ,
J Sex Med. 2013 doi:
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Alteration of gene expression in human cumulus cells as a potential indicator of oocyte aneuploidy.
Fragouli, E, Wells, D, Iager, AE, Kayisli, UA, Patrizio, P,
Hum Reprod. 2012 doi:
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2012 |
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Blastocyst preimplantation genetic diagnosis of a mitochondrial DNA disorder.
Treff, NR, Tao, X, Campos, J, Su, J, Ferry, KM, Levy, B, Scott, R T,
Fertil Steril. 2012 doi:
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2012 |
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2012 |
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Characterization of two heterozygous mutations of the oocyte activation factor phospholipase C zeta (PLC?) from an infertile man by use of minisequencing of individual sperm and expression in somatic cells.
Kashir, J, Konstantinidis, M, Jones, C, Heindryckx, B, Sutter, P, De, Parrington, J, Wells, D, Coward, K,
Fertil Steril. 2012 doi:
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2012 |
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2012 |
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Comprehensive chromosome screening is highly predictive of the reproductive potential of human embryos: a prospective, blinded, nonselection study.
Scott, R T, Ferry, KM, Su, J, Tao, X, Scott, KL, Treff, NR,
Fertil Steril. 2012 doi:
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2012 |
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2012 |
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Development and validation of an accurate quantitative real-time polymerase chain reaction – based assay for human blastocyst comprehensive chromosomal aneuploidy screening. Seminal Contribution.
Treff, NR, Tao, X, Ferry, KM, Su, J, Taylor, D, Scott, R T,
Fertil Steril. 2012 doi:
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2012 |
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2012 |
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2012 |
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2012 |
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Intra-age, intercenter, and intercycle differences in chromosome abnormalities in oocytes.
Munne, S, Held, KR, Magli, CM, Ata, B, Wells, D, Fragouli, E, Baukloh, V, Fischer, R, Gianaroli, L, Fischer, R,
Fertil Steril. 2012 doi:
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2012 |
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Intramuscular progesterone versus Crinone 8% gel for luteal phase support in day 3 cryopreserved embryo transfer.
Kaser, D J, Ginsburg, ES, Missmer, SA, Correia, KF, Racowsky, C,
Fertil Steril. 2012 doi:
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2012 |
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2012 |
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2012 |
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Mid-term neurodevelopmental outcome in isolated mild ventriculomegaly diagnosed in fetal life.
Gomez-Arriaga, P, Herraiz, S, Puente, J M, Zamora-Crespo, B, Núñez-Enamorado, N, Galindo, A,
Diagn Ther. 2012 doi:
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Single embryo transfer with comprehensive chromosome screening results in improved ongoing pregnancy rates and decreased miscarriage rates.
Forman, EJ, Tao, X, Ferry, KM, Taylor, D, Treff, NR, Scott, R T,
Hum Reprod. 2012 doi:
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2012 |
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2012 |
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Successful Live Birth following Preimplantation Genetic Diagnosis for Phenylketonuria in Day 3 Embryos by Specific Mutation Analysis and Elective Single Embryo Transfer.
Lavery, S, Abdo, D, JIMD, Reports, Kotrotsou, M, Trew, G, Konstantinidis, M, Wells, D,
JIMD Reports. 2012 doi:
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2012 |
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The mRNA-binding protein Zfp36 is up-regulated by b-adrenergic stimulation and represses IL-6 production in 3T3-L1 adipocytes.
Brahma, PK, Murray, BS, Shu, F, Sidell, N, Seli, E, Kallen, CB,
Obesity. 2012 doi:
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2012 |
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2012 |
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A maternally inherited autosomal point mutation in human phospholipase C zeta (PLC?) leads to male infertility.
Kashir, J, Konstantinidis, M, Jones, C, Lemmon, B, Lee, HC, Hamer, R, Heindryckx, B, Deane, CM, De, Sutter, P, Fissore, RA, Parrington, J, Wells, D, Coward, K, Deane, CM,
Hum Reprod. 2011 doi:
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2011 |
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2011 |
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2011 |
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Does cessation of progesterone supplementation during early pregnancy in patients treated with recFSH/GnRH antagonist affect ongoing pregnancy rates? A randomized controlled trial.
Kyrou, D, Fatemi, HM, Zepiridis, L, Riva, A, Papanikolaou, EG, Tarlatzis, BC, Devroey, P,
Hum Reprod. 2011 doi:
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Effect of sperm DNA fragmentation on pregnancy outcome depends on oocyte quality
Meseguer, M, Santiso, R, Garrido, N, Garcia-Herrero, S, Remohi, J, Fernandez, JL,
Fertil Steril. 2011 doi:
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2011 |
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Endometrial gene expressions in the window of implantation is altered in obese women especially in association with polycystic ovary syndrome
Bellver, J, Martinez-Conejero, JA, Labarta, E, Alama, P, Melo, MA, Remohi, J, Pellicer, A, Horcajadas, J A,
Fertil Steril. 2011 doi:
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2011 |
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Ex-vivo oocyte retrieval for fertility preservation.
Fatemi, HM, Kyrou, D, Al-Azemi, M, Stoop, D, De, Sutter, P, Bourgain, C, Devroey, P,
Fertil Steril. 2011 doi:
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Is earlier administration of human chorionic gonadotropin (hCG) associated with the probability of pregnancy in cycles stimulated with recombinant follicle-stimulating hormone and gonadotropin-releasing hormone (GnRH) antagonists? A prospective randomized trial.
Kyrou, D, Kolibianakis, EM, Fatemi, HM, Tarlatzis, BC, Tournaye, H, Devroey, P,
Fertil Steril. 2011 doi:
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2011 |
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Long-term use of supplemental vitamins and minerals does not reduce the risk of urothelial cell carcinoma of the bladder in the VITamins And Lifestyle study.
Hotaling, J M, Wright, JL, Pocobelli, G, Bhatti, P, Porter, MP, White, E,
J Urol. 2011 doi:
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2011 |
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2011 |
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SNP Microarray Based Concurrent Screening of 24 Chromosome Aneuploidy and Unbalanced Translocations in Preimplantation Human Embryos.
Treff, NR, Northrop, L, Kasabwala, K, Su, J, Levy, B, Scott, R T,
Fertil Steril. 2011 doi:
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2011 |
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2011 |
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2011 |
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The mRNA-binding protein HuR is regulated in the menstrual cycle and repressed in ectopic endometrium.
Karipcin, S, Altun, T, Kayisli, UA, Guzel, E, Kallen, CB, Seli, E,
Reprod Sci. 2011 doi:
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2011 |
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2011 |
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Validation of microarray comparative genomic hybridization for comprehensive chromosome analysis of embryos.
Gutierrez-Mateo, C, Colls, P, Sanchez-Garcia, J, Escudero, T, Prates, R, Ketterson, K, Wells, D, Munne, S,
Fertil Steril. 2011 doi:
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2011 |
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Accurate single cell 24 chromosome aneuploidy screening using whole genome amplification and single nucleotide polymorphism microarrays.
Treff, NR, Su, J, Tao, X, Levy, B, Scott, R T,
Fertil Steril. 2010 doi:
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2010 |
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Aneploidies in embryos and spermatozoa from patients with Y chromosome microdelections.
Mateu, E, Rodrigo, L, Martinez, MC, Peinedo, V, Delagado, A, MIr, P, Simon, C, Remohi, J,
RBM Online. 2010 doi:
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2010 |
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Cigarette smoking affects specific sperm oxidative defenses but does not cause oxidative DNA damage in infertile men.
Viloria, T, Meseguer, M, Martinez-Conejero, JA, O'Connor, JE, Remohi, J, Pellicer, A, Garrido, N,
Fertil Steril. 2010 doi:
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2010 |
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2010 |
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Comprehensive chromosome screening of polar bodies and blastocysts from couples experiencing repeated implantation failure.
Fragouli, E, Katz-Jaffe, M, Alfarawati, S, Stevens, J, Colls, P, Goodall, N, Tormasi, S, Gutierrez-Mateo, C, Prates, R, Schoolcraft, WB, Munne, S, Wells, D,
Fertil Steril. 2010 doi:
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2010 |
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Cytogenetic analysis of human blastocysts with the use of FISH, CGH and aCGH: scientific data and technical evaluation.
Fragouli, E, Alfarawati, S, Daphnis, D, Goodall, N, Mania, A, Griffiths, T, Gordon, T, Wells, D,
Hum Reprod. 2010 doi:
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2010 |
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GnRH agonist administration at the time of implantation does not improve pregnancy outcome in intrauterine insemination cycles: a randomized controlled tria
Bellver, J, E, Labarta, Bosch, E, Melo, MAB, Vidal, C, Remohi, J, Pellicer, A,
Fertil Steril. 2010 doi:
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Identification and quantification of dopamine receptor 2 in human eutopic and ectopic endometrium: a novel molecular target for endometriosis therapy.
Novella-Maestre, E, Carda, C, Ruiz-Sauri, A, Garcia-Velasco, J A, Simon, C, Pellicer, A,
Biol Reprod. 2010 doi:
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Improved detection of aneuploid blastocysts using a new 12-chromosome FISH test.
Munne, S, Fragouli, E, Colls, P, Katz-Jaffe, MG, Schoolcraft, WB, Wells, D,
RBM Online. 2010 doi:
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Improving FISH diagnosis for preimplantation genetic aneploidy screening
Mir, P, Rodrigo, L, Mateu, E, Milan, M, Mercader, A, Buendia, P, Delgado, A, Pellicer, A, Remohi, J, Rubio, C,
Hum Reprod. 2010 doi:
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Mitotic expression of Spo13 alters M-phase progression and nucleolar localization of Cdc14 in budding yeast.
Varela, E, Schlecht, U, Moina, A, Fackenthal, JD, Washburn, BK, Niederhauser-Wiederkehr, C, Tsai-Pflugfelder, M, Primig, M, Gasser, SM, Esposito, RE,
Genetics. 2010 doi:
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Pregnancy rates alter incubation in new time-lapse incubator (embryoscope) providing detailed information about embryo development compared to incubation in a standard incubator
Meseguer, M, Hilligsøe, KM, Pedersen, KS, Herrero, J, Tejera, A, Garrido, N,
Fertil Steril. 2010 doi:
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Robust embryo identification using polar body single nucleotide polymorphism microarray based DNA fingerprinting.
Treff, NR, Su, J, Kasabwala, N, Tao, X, Miller, KA, Scott, R T,
Fertil Steril. 2010 doi:
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2010 |
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Transmission of Mitochondrial DNA Diseases and Ways to Prevent Them.
Poulton, J, Chiaratti, MR, Meirelles, FV, Kennedy, S, Wells, D, Holt, IJ,
PLoS Genet. 2010 doi:
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Y chromosome microdeletions, sperm DNA fragmentation and sperm oxidative stress as causes of recurrent spontaneous abortion of unknown etiology.
Bellver, J, Meseguer, M, Muriel, L, Garcia-Herrero, S, Barreto, MAM, Garda, AL, Remohi, J, Pellicer, A, Garrido, N, Pellicer, A,
Hum Reprod. 2010 doi:
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Apendicitis y gestación Progresos de Obstetricia y Ginecología.
Blanco, M, Izquierdo, A, Manosalvas, P, Puente, J M, Aznarez, ML,
2009 doi:
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Comparative genomic hybridization of oocytes and first polar bodies from young donors.
Fragouli, E, Escalona, A, Gutierrez-Mateo, C, Tormasi, S, Alfarawati, S, Sepulveda, S, Wells, D, Munne, S,
RBM Online. 2009 doi:
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Endometrial fluid is a specific and non-invasive biological sample for protein biomarker identification in endometriosis.
Ametzazurra, A, Matorras, R, Garcia-Velasco, J A, Prieto, B, Simon, L, Martinez, A, Nagore, D,
Hum Reprod. 2009 doi:
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GnRH agonist versus recombinant HCG in an oocyte donation programme: a randomized, prospective, controlled, assessor-blind study.
Melo, M, Busso, CE, Bellver, J, Alama, P, Garrido, N, Meseguer, M, Pellicer, A, Remohi, J,
RBM Online. 2009 doi:
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Lte1, Cdc14 and MEN-controlled Cdk inactivation in yeast coordinate rDNA decompaction with late telophase progression.
Varela, E, Shimada, K, Laroche, T, Leroy, D, Gasser, SM,
EMBO J. 2009 doi:
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Sperm DNA fragmentation levels in testicular sperm samples from azoospermic males as assessed by the sperm chromatin dispersion (SCD) test.
Meseguer, M, Santiso, R, Garrido, N, Gil-Salom, M, Remohi, J, Fernandez, J,
Fertil Steril. 2009 doi:
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TGF-beta regulates expression of transcription factor KLF6 and its splice variants, and promotes co-operative transactivation of common target genes through a Smad3/Sp1/KLF6 interaction.
Botella, LM, Sanz-Rodriguez, F, Komi, Y, Fernandez-L, A, Varela, E, Garrido-Martin, EM, Narla, G, Friedman, SL, Kojima, S, Friedman, SL,
Biochem J. 2009 doi:
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Birth of a healthy boy after a double factor PGD in a couple carrying a genetic disease and at risk for aneuploidy.
Obradors, A, Fernandez, E, Oliver-Bonet, M, Rius, M, de, la, Fuente, A, Wells, D, Benet, J, Navarro, J,
Hum Reprod. 2008 doi:
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Functional localization of DNA damage to pore complex bound to Slx5/8 SUMO-dependent E3 ligase
Nagai, S, Dubrana, K, Tsai-Pflufelder, M, Davidson, M, Roberts, T, Brown, G, Varela, E, Hediger, F, Gasser, SM, Krogan, NJHediger, F,
Science. 2008 doi:
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Noninvasive metabolomic profiling of human embryo culture media using Raman spectroscopy predicts embryonic reproductive potential: a prospective blinded pilot
Scott, R T, Seli, E, Miller, K, Sakkas, D, Scott, K, Burns, DH,
Fertil Steril. 2008 doi:
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Técnica de B-Lynch en el control de la hemorragia posparto Progresos de Obstetricia
Blanco, M, Gomez, E, Manosalvas, P, Izquierdo, A, Puente, J M, Hernandez, Garcia, JM,
Ginecología. 2008 doi:
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Fresh human orthotopic ovarian córtex transplantation: long-term results.
Sanchez, M, Alama, P, Gadea, B, Soares, S R, Simon, C, Pellicer, A,
Hum Reprod. 2007 doi:
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Non-Invasive metabolomic profiling of human embryo culture media using Raman and near infrared spectroscopy correlates with reproductive potential of embryos in women undergoing in vitro fertilization.
Seli, E, Sakkas, D, Scott, R T, Kwok, JS, Rosendahl, S, Burns, DH,
Fertil Steril. 2007 doi:
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Salpingectomy increases peri-implantation endometrial HOXA10 expression in women with hydrosalpinx.
Daftary, GS, Kayisli, UA, Seli, E, Bukulmez, O, Arici, A, Taylor, HS,
Fertil Steril. 2007 doi:
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Characterization of a human Bid homologue protein from Gallus gallus.
Diaz-Gil, G, Gomez-Esquer, F, Agudo, D, Delcan, J, Martinez-Arribas, F, Rivas, C, Schneider, J, Palomar, MA, Linares, R, Palomar, MA,
Gene. 2006 doi:
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Heteroparental blastocyst production from microsurgically corrected tripronucleated human embryos.
Escriba, M J, Martin, J, Rubio, C, Valbuena, D, Remohi, J, Pellicer, A, Simon, C,
Fertil Steril. 2006 doi:
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J.Ultrastructure of preimplantation genetic diagnosis-derived human blastocysts grown in a coculture system after vitrification.
Escriba, M J, Escobedo-Lucea, C, Mercader, A, De, Los, Santos, MJ, Pellicer, A, Remohi, J,
Fertil Steril. 2006 doi:
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Association of abnormal morphology and altered gene expression in human preimplantation embryos.
Wells, D, Bermúdez, MG, Steuerwald, N, Malter, HE, Thornhill, AR, Cohen, J,
Fertil Steril. 2005 doi:
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Expression of genes regulating chromosome segregation, the cell cycle and apoptosis during human preimplantation development.
Wells, D, Bermudez, MG, Steuerwald, N, Thornhill, AR, Walker, DL, Malter, H, Delhanty, JDA, Cohen, J,
Hum Reprod. 2005 doi:
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A new follicle aspiration set is equally effective and as well tolerated as the standard needle when used in a prospective randomized trial in a large in vitro fertilization program.
Miller, KA, Elkind-Hirsch, K, Benson, M, Bergh, P, Drews, M, Scott, R T,
Fertil Steril. 2004 doi:
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A proteomic approach to study Salmonella typhi periplasmic proteins altered by a lack of the DsbA thiol: disulfide isomerase.
Agudo, D, Mendoza, MT, Castañares, C, Nombela, C, Rotger, R,
Proteomics. 2004 doi:
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Expression profiles of individual human oocytes using microarray technology.
Bermúdez, MG, Wells, D, Malter, H, Munne, S, Cohen, J, Steuerwald, NM,
RBM Online. 2004 doi:
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Microarrays for Analysis and Diagnosis of Human Embryos
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Fertil Steril. 2004 doi:
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MUC1 e IL-6: posibles marcadores de fertilidad en reproducción humana.
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ASEBIR. 2004 doi:
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Reliability of comparative genomic hybridization to detect chromosome abnormalities in first polar bodies and metaphase II oocytes.
Gutierrez-Mateo, C, Wells, D, Benet, J, Sanchez-Garcia, JF, Bermúdez, MG, Belil, I, Egozcue, J, Munne, S, Navarro, J, Munne, S,
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A cross-talk between hypoxia and TGF-? orchestrates erytropoietin gene regulation through SP1 and SMADS.
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Early maternal hypothyroxinemia alters histogenesis and cerebral cortex cytoarchitecture of the progeny.
Lavado-Autric, R, Auso, E, Garcia-Velasco, J A, Arufe, Mdel, C, Escobar, del, Rey, F, Berbel, P, Berbel, P, Morreale, de, Escobar, G,
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Single-cell sequencing and mini-sequencing for preimplantation genetic diagnosis.
Bermudez, MG, Piyamongkol, W, Tomaz, S, Dudman, E, Sherlock, JK, Wells, D,
Prenat Diagn. 2003 doi:
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Comparison of polymerase chain reaction–dependent methods for determining the presence of human immunodeficiency virus and hepatitis C virus in washed sperm.
Meseguer, M, Garrido, N, Gimeno, C, Remohi, J, Simon, C, Pellicer, A,
Fertil Steril. 2002 doi:
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First clinical application of comparative genomic hybridization and polar body testing for preimplantation genetic diagnosis of aneuploidy.
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Fertil Steril. 2002 doi:
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Preimplantation genetic diagnosis for single gene disorders: experience with five single gene disorders.
Harper, JC, Wells, D, Piyamongkol, W, Abou-Sleiman, P, Apessos, A, Ioulianos, A, Davis, M, Doshi, A, Serhal, P, Ranieri, M, Rodeck, C, Delhanty, JDA,
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2002 |
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2002 |
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2002 |
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Testicular sperm extraction (TESE) and intracytoplasmic sperm injection (ICSI) results in secondary azoospermic patients after chemotherapy.
Garrido, N, Meseguer, M, Gil-Salom, M, Simon, C, Remohi, J, Pellicer, A,
Fertil Steril. 2002 doi:
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2002 |
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2002 |
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The "vanishing embryo" phenomenon in an oocyte donation programme.
Rodriguez-Gonzalez, M, Serra, V, Garcia-Velasco, J A, Pellicer, A, Remohi, J,
Fertil Steril. 2002 doi:
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2002 |
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2002 |
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2002 |
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2002 |
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2002 |
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A successful strategy for preimplantation genetic diagnosis of myotonic dystrophy using multiplex fluorescent PCR.
Piyamongkol, W, Harper, JC, Sherlock, JK, Doshi, A, Serhal, PF, Delhanty, JDA, Wells, D,
Prenat Diagn. 2001 doi:
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2001 |
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Acrocentric chromosome disomy is increased in spermatozoa from fathers of Turner syndrome patients
Soares, S R, Vidal, F, Bosch, M, Martinez-Pasarell, O, Nogues, C, Egozcue, J, Templado, C,
Hum Genet. 2001 doi:
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2001 |
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2001 |
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2001 |
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2001 |
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Estrogen inhibits monocyte chemotactic protein-1 production in human coronary artery smooth muscle cells: A mechanism for its anti-atherogenic effect.
Seli, E, Selam, B, Mor, G, Kayisli, UA, Pehlivan, T, Arici, A,
Menopause. 2001 doi:
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2001 |
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2001 |
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2001 |
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2001 |
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2001 |
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Numerical chromosome abnormalities in the spermatozoa of the fathers of children with trisomy 21 of paternal origin: generalised tendency to meiotic non-disjunction.
Soares, S R, Templado, C, Blanco, J, Egozcue, J, Vidal, F,
Hum Genet. 2001 doi:
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2001 |
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2001 |
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2001 |
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2001 |
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2001 |
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2001 |
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2000 |
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2000 |
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2000 |
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2000 |
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2000 |
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2000 |
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Deletion and duplication of the adenomatous polyposis coli gene resulting from an interchromosomal insertion involving 5 (q22q23.3) in the father.
Hastings, RJ, Svennevik, EC, Setterfield, B, Wells, D, Delhanty, JDA, Mackinnon, H,
J Med Genet. 2000 doi:
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2000 |
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2000 |
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2000 |
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2000 |
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Empty follicle syndrome: evidence for recurrence.
Zreik, TG, Garcia-Velasco, J A, Vergara, TM, Arici, A, Olive, D, Jones, EE,
Hum Reprod. 2000 doi:
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2000 |
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2000 |
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2000 |
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2000 |
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2000 |
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2000 |
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2000 |
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1999 |
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1999 |
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1999 |
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Human embryo fragmentation in vitro and its implications for pregnancy and implantation
Alikani, M, Cohen, H, Tomkin, G, Garrisi, GJ, Mack, C, Scott, R T,
Fertil Steril. 1999 doi:
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1999 |
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1999 |
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1999 |
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1999 |
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Positive outcome after preimplantation diagnosis of aneuploidy in human embryos.
Munne, S, Magli, C, Cohen, J, Morton, P, Sadowy, S, Gianaroli, L, Tucker, M, Marquez, C, Sable, D, Ferraretti, AP, Massey, JB, Scott, R T,
Hum Reprod. 1999 doi:
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1999 |
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1999 |
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Unicornuate uterus with a rudimentary horn and ovarian dysgerminoma. A case report.
Zreik, TG, Pustilnik, TB, Garcia-Velasco, J A, Rutherford, T, Troiano, RN, Olive, DL,
J Reprod Med. 1999 doi:
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1999 |
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1998 |
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1998 |
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1998 |
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1998 |
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1998 |
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1998 |
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1998 |
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1998 |
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Synthesis and differentially regulated processing of proinsulin in developing chick pancreas, liver and neuroretina.
Alarcon, C, Serna, J, Perez-Villamil, B, De, Pablo, F,
FEBS Lett. 1998 doi:
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1998 |
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1998 |
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1998 |
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1998 |
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Birth of infant after transfer of anucleate donor oocyte cytoplasm into recipient eggs.
Cohen, J, Scott, R T, Schimmel, T, Levron, J, Willadsen, S,
Lancet. 1997 doi:
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1997 |
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1997 |
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1997 |
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1997 |
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1997 |
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1997 |
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1997 |
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Structure and chromosomal mapping of the mouse P2X3 gene.
Souslova, V, Ravenall, S, Fox, M, Wells, D, Wood, JN, Akopian, AN,
Gene. 1997 doi:
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1997 |
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APC gene mutation and DNA microsatellite instability in pancreatic cancers of UK origin.
See, CG, Sud, R, Wells, D, Bowles, L, Ding, S, Habib, N, Delhanty, JDA,
GI Cancer 2. 1996 doi:
|
1996 |
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Differential and tissue-specific regulation of (pro)insulin and insulin-like growth factor-I mRNAs and levels of thyroid hormones in growth-retarded embryos.
Serna, J, Gonzalez-Guerrero, PR, Scanes, CG, Prati, M, Morreale, G, De, Pablo, F,
Growth Regul. 1996 doi:
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1996 |
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1996 |
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1996 |
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1996 |
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Repercusión of the hormonal substitute therapy in the antitrombin III.
Seara, S, Guillen, V, Santiago, L, Blanco, C, Rodriguez, R, Morin, S J, Garcia, JA,
Endocrinology. 1996 doi:
|
1996 |
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1995 |
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Rapid detection of rare variants and common polymorphisms in the APC gene by PCR-SSCP for presymptomatic diagnosis and showing allele loss.
Gayther, SA, Sud, R, Wells, D, Tsioupra, K, Delhanty, JD,
J Med Genet. 1995 doi:
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1995 |
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1995 |
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1995 |
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1994 |
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Regionally clustered APC mutations are associated with a severe phenotype and occur at a high frequency in new mutation cases of adenomatous polyposis coli.
Gayther, SA, Wells, D, SenGupta, SB, Chapman, P, Neale, K, Tsioupra, K, Delhanty, JDA,
Hum Mol Genet. 1994 doi:
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1994 |
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Tru-trax in vitro cervical mucus penetration testing
Sharara, FI, Beatse, SN, Bailey, SA, Neal, GK, Coddington, CC, Scott, R T,
Hum Reprod. 1994 doi:
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1994 |
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1990 |
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1990 |
-
Effects of the severity of tubo-ovarian disease and previous tubal surgery on the results of in vitro fertilization and embryo transfer.
Oehninger, SC, Scott, R T, Muasher, SJ, Acosta, AA, Jones, HW, Rosenwaks, Z,
Fertil Steril. 1989 doi:
|
1989 |
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1989 |
-
Validation of the hemizona assay (HZA) in a monkey model: Influence of oocyte maturational stages.
Oehninger, SC, Coddington, CC, Scott, R T, Franken, D, Acosta, AA, Hodgen, GD,
Fertil Steril. 1989 doi:
|
1989 |
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1988 |
-
The effect of interobserver variation in dating endometrial histology in the diagnosis of luteal phase defects.
Scott, R T, Snyder, RR, Strickland, DM, Tyburski, CC, Bagnall, JA, Reed, KR, Adair, CA, Hensley, SB,
Fertil Steril. 1988 doi:
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1988 |
