George Patounakis, M.D., Ph.D.

Medical Director at RMA of Florida

RMA Florida

Biografía

Dr. George Patounakis, MD, PhD, FACOG is an attending physician at Reproductive Medicine Associates of Florida where he serves as medical director and Assistant Professor at University of Central Florida in the Department of Obstetrics and Gynecology.

He received his B.S. in Electrical Engineering with highest honors from Rutgers University’s College of Engineering. He then earned his Masters of Philosophy and Masters of Science in Electrical Engineering at Columbia University before receiving his doctorate in Electrical Engineering with Distinction. His doctoral thesis work was on low-cost integrated DNA microarray platforms, which resulted in a U.S. patent.

Dr. Patounakis received his M.D. from Rutgers – Robert Wood Johnson Medical School and earned numerous academic excellence awards in addition to the Stanley S. Bergen Medal of Excellence, which was the school’s highest student honor. He completed his internship and residency in OB/GYN at Thomas Jefferson University Hospital where he served as Administrative Chief Resident. Dr. Patounakis pursued his fellowship training in Reproductive Endocrinology and Infertility at the National Institutes of Health in Bethesda, Maryland. While at the NIH, his research focused on cholesterol transport in steroidogenic cells using live-cell microscopy, IVF outcome predictors, and genetic influences on infertility.
Dr. Patounakis has authored and contributed to numerous peer reviewed publications in both the fields of engineering and medicine. He serves as an Ad Hoc Reviewer for the Journal of Assisted Reproduction Genetics and Fertility & Sterility. He has also authored the chapter on gonadal dysfunction and fertility preservation in the widely used oncology textbook DeVita, Hellman, and Rosenberg’s Cancer: Principles & Practice of Oncology. His research interests include statistical modeling of IVF cycles, diminished ovarian reserve, and fertility preservation.

BS	Rutgers University – College of Engineering (2000)
MS	Columbia University (2001)
MPhil	Columbia University (2003)
PhD	Columbia University (2005)
Residency	Thomas Jefferson University Hospital (2013)
Fellowship	National Institutes of Health (2016)

Honores y reconocimientos

Best New Investigator Poster Award – Society of Reproductive Investigation	2016
Howard Lees Kent Memorial Prize	2013
Resident Research Award	2013
Dr. B. Frank Lovett Memorial Fund Award	2012
Stanley S. Bergen Medal of Excellence	2009
Academic Achievement Award	2009
Academic Excellence Award in OB/GYN	2009
Academic Excellence Award in Pathology	2009
Academic Excellence Award in Pharmacology	2009
Academic Excellence Award in Biochemistry	2009
Ph.D. awarded with departmental distinction	2005
Intel PhD Fellowship	2004
Low Power Design Contest Award	2003
Columbia School of Engineering Presidential Fellowship	2000
James J. Slade Scholar	2000

Publicaciones

The Appraisal of Body Content (ABC) trial: increased male or female adiposity does not significantly impact in vitro fertilization laboratory or clinical outcomes
Kim J Patounakis G Juneau C Morin SJ Neal S Bergh P Seli E Scott RT
Fertil Steril. 2021 Feb 10:S0015-0282(21)00026-1. doi: 10.1016/j.fertnstert.2020.12.037. Online ahead of print.

Embryo's Natural Motion (enMotion): a paired randomized controlled trial evaluating a dynamic embryo culture system.
Juneau CR Tiegs AW Franasiak JM Goodman LR Whitehead C Patounakis G Scott RT Jr
Fertil Steril. 2020 Mar;113(3):578-586.e1. doi: 10.1016/j.fertnstert.2019.09.043. Epub 2020 Feb 7

The appraisal of body content (ABC) trial: obesity does not significantly impact gamete production in infertile men and women.
Kim J Juneau C Patounakis G Morin S Neal S Seli E Scott RT
J Assist Reprod Genet. 2020 Aug 22. doi: 10.1007/s10815-020-01930-3. Online ahead of print.

A multicenter, prospective, blinded, nonselection study evaluating the predictive value of an aneuploid diagnosis using a targeted next-generation sequencingbased preimplantation genetic testing for aneuploidy assay and impact of biopsy
Ashley W Tiegs Tao X Zhan Y Whitehead C Julia Kim Brent Hanson Emily Osman JKim T Patounakis G Gutmann J Arthur Castelbaum Seli E Jalas C Richard TScott Jr
Fertility and SterilityIn press, corrected proofAvailable online 28 August 2020

Three-dimensional ultrasound diagnosis of adenomyosis is not associated with adverse pregnancy outcomes following single thawed euploid blastocyst transfer: a prospective cohort study.
Neal S Morin S Werner M Gueye NA Pirtea P Patounakis G Richard S Jr Goodman L
Ultrasound Obstet Gynecol. 2020 Apr 29. doi: 10.1002/uog.22065. Online ahead of print.

Erratum. Worth the wait? Day 7 blastocysts have lower euploidy rates but similar sustained implantation rates as Day 5 and Day 6 blastocysts.
Tiegs AW Sun L Patounakis G Scott RT
Hum Reprod. 2019 Nov 26. pii: dez219. doi: 10.1093/humrep/dez219. [Epub ahead of print] No abstract available.

Sperm DNA fragmentation on the day of fertilization is not associated with embryologic or clinical outcomes after IVF/ICSI.
Green KA Patounakis G Dougherty MP Werner MD Scott RT Franasiak JM
J Assist Reprod Genet. 2019 Nov 21. doi: 10.1007/s10815-019-01632-5. [Epub ahead of print]

Worth the wait? Day 7 blastocysts have lower euploidy rates but similar sustained implantation rates as Day 5 and Day 6 blastocysts.
Tiegs AW Sun L Patounakis G Scott RT
Hum Reprod. 2019 Aug 12. pii: dez138. doi: 10.1093/humrep/dez138. [Epub ahead of print]

Embryonic aneuploidy rates are equivalent in natural cycles and gonadotropin-stimulated cycles.
Hong KH Franasiak JM Patounakis G Juneau CR Scott RT
Fertil Steril. 2019 Oct;112(4):670-676. doi: 10.1016/j.fertnstert.2019.05.039.

The preimplantation genetic testing debate continues: first the hype, then the tension, now the hypertension?
Patounakis G Hill MJ
Fertil Steril. 2019 May 27. pii: S0015-0282(19)30407-8. doi: 10.1016/j.fertnstert.2019.04.028. [Epub ahead of print] No abstract available.

Adjusting for age: is it enough to just say you did it?
Patounakis G Hill MJ
Fertil Steril. 2019 Jan 2. pii: S0015-0282(18)32204-0. doi: 10.1016/j.fertnstert.2018.11.009. [Epub ahead of print] No abstract available.

Diminished ovarian reserve and poor response to stimulation in patients <38 years old: a quantitative but not qualitative reduction in performance.
Morin SJ Patounakis G Juneau CR Neal SA Scott RT Seli E
Hum Reprod, 33(8):1489-1498, 2018.

Clinical trial registry alone is not adequate: on the perception of possible endpoint switching and P-hacking.
Hill MJ Connell MT Patounakis G
Hum Reprod, 33(2):341-342, 2018.

Complexities and potential pitfalls of clinical study design and data analysis in assisted reproduction.
Patounakis G Hill MJ
Curr Opin Obstet Gynecol, 30(3):139-144, 2018.

Patients with endometriosis have aneuploidy rates equivalent to their age-matched peers in the IVF population
Juneau C Kraus E Werner MD Franasiak JM Morin SJ Patounakis G Molinaro T de Ziegler D Scott RT
Fertil Steril, 108: 284-288, 2017.

Patients with endometriosis have aneuploidy rates equivalent to their age-matched peers in the in vitro fertilization population.
Juneau C Kraus E Werner MD Franasiak JM Morin SJ Patounakis G Molinaro T De Ziegler D Scott RT
Fertil Steril, 108(2):284-288, 2017.

Does premature elevated progesterone on the day of trigger increase spontaneous abortion rates in fresh and subsequent frozen embryo transfers?
Healy M Patounakis G Zanelotti A Devine K DeCherney A Levy M Hill MJ
Gynecol Endrocrinol, 33:472-5. 2017

The slow growing embryo and premature progesterone elevation: compounding factors for embryo-endometrial asynchrony.
Healy MW Yamasaki M Patounakis G Richter KS Devin K DeCherney AH Hill MJ
Hum Reprod, 32:362-7. 2017.

Revisiting the progesterone oocyte ratio.
Hill MJ Healy MW Richter KS Widra E Levens ED DeCherney AH Patounakis G Whitcomb BW
Fertil Steril, 107:671-6. 2017.

Characterization of reproductive endocrinology and infertility (REI) fellowship applicants: guiding our mentees toward success.
Franasiak JM Kaser DJ Goodman L Patounakis G Juneau C Morin SJ Neal S Schlaff W Scott RT
Fertil Res Pract. 2017 Dec 8;3:18. doi: 10.1186/s40738-017-0045-x. eCollection 2017.

Patients with endometriosis have aneuploidy rates equivalent to their age-matched peers in the in vitro fertilization population.
Juneau C Kraus E Werner MD Franasiak JM Morin SJ Patounakis G Molinaro T De Ziegler D Scott RT
Fertil Steril. 2017 Jun 23. pii: S0015-0282(17)30421-1. doi: 10.1016/j.fertnstert.2017.05.038. [Epub ahead of print]

Is the effect of premature elevated progesterone augmented by human chorionic gonadotropin versus gonadotropin-releasing hormone agonist trigger?
Connell MT Patounakis G Healy MW DeCherney AH Devine K Widra E Levy MJ Hill MJ
Fertil Steril, 106:584-9. 2016

Does a frozen embryo transfer ameliorate the effect of elevated progesterone seen in fresh transfer cycles?
Healy MW Patounakis G Connell MT Devine K DeCherney AH Levy MJ Hill MJ
Fertil Steril, 105:93-9. 2016.

Why abandoning sustained implantation rate may be throwing the baby out with the bathwater
Forman EJ Franasiak JM Patounakis G Scott RT
Hum Reprod, 31:1926-7. 2016.

The impact of a prior Cesarean delivery on embryo transfer: a prospective study.
Patounakis G Ozcan MC Chason RJ Norian JM Payson M DeCherney AH Yauger BJ
Fertil Steril, 106:311-6. 2016.

Is the effect of premature elevated progesterone augmented by human chorionic gonadotropin versus gonadotropin-releasing hormone agonist trigger?
Connell MT Patounakis G Healy MW DeCherney AH Devine K Widra E Levy MJ Hill MJ
Fertil Steril, 106:584-9. 2016.

Is FMR1 CGG repeat length a predictor of in vitro fertilization stimulation response or outcome?
Banks N Patounakis G Devine K DeCherney AH Widra EA Levens ED Whitcomb BW Hill MJ
Fertil Steril, 105:1537-46. 2016.

Why abandoning sustained implantation rate may be throwing the baby out with the bathwater.
Forman E Franasiak JM Patounakis G Scott RT
Hum Reprod 31:1926-7.

Multiple thrombophilic single nucleotide polymorphisms lack a significant effect on outcomes in fresh IVF cycles: an analysis of 1717 patients.
Patounakis G Bergh E Forman E Tao X Lonczak A Franasiak JM Treff N Scott RT
J Assist Reprod Genet, 33:67-73, 2016.

Genetic associations with diminished ovarian reserve: a systematic review of the literature.
Greene AD Patounakis G Segars JH
J Assist Reprod Genet, 31:935-46. 2014.

Development of pelvic abscess during pregnancy following transvaginal oocyte retrieval and in vitro fertilization
Patounakis G Krauss K Nicholas S Baxter JK Rosenblum NG Berghella V
Eur J Obstet Gynecol Reprod Biol., 164:116-7. 2012.

The p53 codon 72 single nucleotide polymorphism lacks a significant effect on implantation rate in fresh in vitro fertilization cycles: an analysis of 1,056 patients.
Patounakis G Treff N Tao X Lonczak A Scott RT Frattarelli JL
Fertil Steril, 92:1290-6. 2009.

The p53 codon 72 single nucleotide polymorphism lacks a significant effect on implantation rate in fresh in vitro fertilization cycles: an analysis of 1,056 patients
Patounakis G Treff N Tao X Lonczak A Scott RT Frattarelli J
Fertil Steril, 92:1290-6, 2009.

Pulse current-mode signalling for nearly speed-of-light intrachip communcations
Jose AP Patounakis G Shepard KL
IEEE J Solid-State Circuits, 41:772-80. 2006

Active CMOS array sensor for time-resolved fluorescence detection.
Patounakis G Shepard KL Levicky R
IEEE J Solid-State Circuits, 41:2521-30. 2006

Near Speed-of-Light On-Chip Interconnects Using Pulsed Current-Mode Signaling.
Jose AP Patounakis G Shepard KL
2005 Symposium on VLSI Circuits, 108-11. 2005.

A Fully Integrated On-Chip DC-DC Conversion and Power Management System.
Patounakis G Li YW Shepard KL
IEEE J Solid-State Circuits, 39:443-51. 2004.

High-throughput asynchronous datapath with software-controlled voltage scaling.
Li YW Patounakis G Shepard KL Nowick SM
IEEE J Solid-State Circuits, 39:704-8. 2004

Asynchronous datapath with software-controlled on-chip adaptive voltage scaling for multirate signal processing applications.
Li YW Patounakis G Jose AP Shepard KL
2003 IEEE International Symposium on Asynchronous Circuits and Systems, 216-25. 2003.

Two-step metalorganic chemical vapor deposition growth of piezoelectric ZnO thin film on SiO2/Si substrate.
Muthukumar S Emanetoglu NW Patounakis G Gorla CR Liang S Lu Y
J Vac Sci Technol A, 19:1850-3. 2001.

Analysis of SAW properties of epitaxial ZnO films grown on R-Al2O3 substrates.
Emanetoglu NW Patounakis G Liang S Gorla CR Wittstruck R Lu Y
IEEE Trans Ultrason Ferroelectr Freq Control, 48:1389-94. 2001.

Analysis of temperature compensated SAW modes in ZnO/SiO2/Si multilayer structures
Emanetoglu NW Patounakis G Muthukumar S Lu Y
2000 IEEE Ultrasonics Symposium, 1:325-8. 2000

Virtual Reality Training for the Diagnosis of Prostate Cancer.
Burdea G Patounakis G Popescu V Weiss RE
VRAIS '98 Proceedings of the Virtual Reality Annual International Symposium, 190-7. 1998.

Tiegs AW Tao X Zhan Y Whitehead CV Hanson BM Kim JG Osman EK Seli E Patounakis G Gutmann J Castelbaum AJ Kim T Chaim Jalas O-77 TRANSFER OUTCOMES OF EMBRYOS WITH PREIMPLANTATION GENETIC TESTING FOR ANEUPLOIDY (PGT-A) DIAGNOSES OF UNDETERMINED REPRODUCTIVE POTENTIAL: RESULTS FROM A PROSPECTIVE, BLINDED, MULTI-CENTER NON-SELECTION STUDY. Presented at 76th American Society of Reproductive Medicine Scientific Congress, Virtual congress, October 17-21,2020

Tiegs A Tao X Whitehead Neal S Osman E Kim J Hanson B Seli E Patounakis G Gutmann JN Castelbaum AJ Scott RT O-084 A multi-center, prospective, blinded, non-selection study evaluating the predictive value (PV) of an aneuploid preimplantation genetic testing for aneuploidy (PGT-A) diagnosis and impact of biopsy. Presented at the 67th Annual Meeting of the Society for Reproductive Investigation, Vancouver ,Canada, March 10-14, 2020

Kim G Patounakis G Juneau C Morin SJ Neal SA Tiegs AW Osman EK Hanson BM Scott RT P-268 ABC TRIAL: BODY MASS INDEX AND PERCENTAGE BODY FAT ARE NOT DIFFERENT IN POSITIVE PREDICTIVE VALUE OF MISCARRIAGE OR PRETERM DELIVERY IN PATIENTS UNDERGOING IVF. Presented at the 35th annual meeting of the European Society of Human Reproduction and Embryology, Vienna, Austria, 14-16 October 2019

Neal SA Morin SJ Werner MD Gueye N Pirtea P Patounakis G Scott RT Goodman LR O-214 THREE-DIMENSIONAL ULTRASOUND DIAGNOSIS OF ADENOMYSIS IS NOT ASSOCIATED WITH DIMINISHED LIVE BIRTH FOLLOWING SINGLE THAWED EUPLOID BLASTOCYST TRANSFER: A PROSPECTIVE COHORT STUDY. Presented at the 35th annual meeting of the European Society of Human Reproduction and Embryology, Vienna, Austria, 14-16 October 2019

Tiegs AW Tao X Whitehead CR Neal SA Osman EK Kim G Hanson BM Seli E Patounakis G Gutmann J Castlebaum A O-74 DOES PREIMPLANTATION GENETIC TESTING FOR ANEUPLOIDY (PGT-A) HARM EMBRYOS? NO—A MULTI-CENTER, PROSPECTIVE, BLINDED, NON-SELECTION STUDY EVALUATING THE PREDICTIVE VALUE OF AN ANEUPLOID DIAGNOSIS AND IMPACT OF BIOPSY. Presented at the 35th annual meeting of the European Society of Human Reproduction and Embryology, Paris, France, 14-16 October 2019

Kim G Morin SJ Patounakis G Juneau C Neal SA Abc trial: appraisal of body content. Frozen embryo cycles are not impacted by the negative effects of obesity seen in fresh cycles. Presented at the 65th Annual Meeting of the Society for Reproductive Investigation, San Diego,CA,USA, October 6-10, 2018

Morin SJ Patounakis G Juneau CR Neal SA Scott RT Seli E Quantity versus quality: do patients with diminished ovarian reserve (DOR) and poor response to stimulation also exhibit poor blastulation and increased aneuploidy . , , October 28-November 1,2017

George Patounakis, M.D., Ph.D.

Biografía

Formación

Honores y reconocimientos

Publicaciones

Presentations