George Patounakis, M.D., Ph.D.

Biografía

Dr. George Patounakis, MD, PhD, FACOG is an attending physician at Reproductive Medicine Associates of Florida where he serves as medical director and Assistant Professor at University of Central Florida in the Department of Obstetrics and Gynecology.

He received his B.S. in Electrical Engineering with highest honors from Rutgers University’s College of Engineering. He then earned his Masters of Philosophy and Masters of Science in Electrical Engineering at Columbia University before receiving his doctorate in Electrical Engineering with Distinction. His doctoral thesis work was on low-cost integrated DNA microarray platforms, which resulted in a U.S. patent.

Dr. Patounakis received his M.D. from Rutgers – Robert Wood Johnson Medical School and earned numerous academic excellence awards in addition to the Stanley S. Bergen Medal of Excellence, which was the school’s highest student honor. He completed his internship and residency in OB/GYN at Thomas Jefferson University Hospital where he served as Administrative Chief Resident. Dr. Patounakis pursued his fellowship training in Reproductive Endocrinology and Infertility at the National Institutes of Health in Bethesda, Maryland. While at the NIH, his research focused on cholesterol transport in steroidogenic cells using live-cell microscopy, IVF outcome predictors, and genetic influences on infertility.
Dr. Patounakis has authored and contributed to numerous peer reviewed publications in both the fields of engineering and medicine. He serves as an Ad Hoc Reviewer for the Journal of Assisted Reproduction Genetics and Fertility & Sterility. He has also authored the chapter on gonadal dysfunction and fertility preservation in the widely used oncology textbook DeVita, Hellman, and Rosenberg’s Cancer: Principles & Practice of Oncology. His research interests include statistical modeling of IVF cycles, diminished ovarian reserve, and fertility preservation.

Formación

BS	Rutgers University - College of Engineering (2000)
MS	Columbia University (2001)
MPhil	Columbia University (2003)
PhD	Columbia University (2005)
Residency	Thomas Jefferson University Hospital (2013)
Fellowship	National Institutes of Health (2016)

Honores y reconocimientos

Best New Investigator Poster Award – Society of Reproductive Investigation	2016
Howard Lees Kent Memorial Prize	2013
Resident Research Award	2013
Dr. B. Frank Lovett Memorial Fund Award	2012
Stanley S. Bergen Medal of Excellence	2009
Academic Achievement Award	2009
Academic Excellence Award in OB/GYN	2009
Academic Excellence Award in Pathology	2009
Academic Excellence Award in Pharmacology	2009
Academic Excellence Award in Biochemistry	2009
Ph.D. awarded with departmental distinction	2005
Intel PhD Fellowship	2004
Low Power Design Contest Award	2003
Columbia School of Engineering Presidential Fellowship	2000
James J. Slade Scholar	2000

Publicaciones

Missing an important finding: why overly generalizable studies are a double-edged sword.
Patounakis G, Hill MJ

Fertil Steril. 2021 doi:

The Appraisal of Body Content (ABC) trial: increased male or female adiposity does not significantly impact in vitro fertilization laboratory or clinical outcomes
Kim J, Patounakis G, Juneau C, Morin S, Neal S, Bergh P, Seli E, Scott R T

Fertil Steril. Feb. 2021 doi: 10.1016/j.fertnstert.2020.12.037

The Appraisal of Body Content (ABC) trial: increased male or female adiposity does not significantly impact in vitro fertilization laboratory or clinical outcomes
Kim J, Patounakis G, Juneau C, Morin S J, Neal S, Bergh P, Seli E, Scott R T,

Fertil Steril. 10-Feb. 2021 doi: 10.1016/j.fertnstert.2020.12.037

A multicenter, prospective, blinded, nonselection study evaluating the predictive value of an aneuploid diagnosis using a targeted next-generation sequencing-based preimplantation genetic testing for aneuploidy assay and impact of biopsy
Tiegs A W, Tao X, Zhan Y, Whitehead C, Kim J, Hanson B, Osman E, Kim T J, Patounakis G, Gutmann J, Castelbaum A, Seli E, Jalas C, Scott R T,

Fertil Steril. Mar. 2021 doi: 10.1016/j.fertnstert.2020.07.052

The appraisal of body content (ABC) trial: obesity does not significantly impact gamete production in infertile men and women
Kim J, Juneau C, Patounakis G, Morin S J, Neal S, Seli E, Scott R T,

J Assist Reprod Genet. Nov. 2020 doi: 10.1007/s10815-020-01930-3

Three-dimensional ultrasound diagnosis of adenomyosis is not associated with adverse pregnancy outcome following single thawed euploid blastocyst transfer: prospective cohort study
Neal S, Morin S J, Werner M D, Gueye N A, Pirtea P, Patounakis G, Scott R T, Goodman L,

Ultrasound Obstet Gynecol. Oct. 2020 doi: 10.1002/uog.22065

Embryo's Natural Motion (enMotion): a paired randomized controlled trial evaluating a dynamic embryo culture system
Juneau C R, Tiegs A W, Franasiak J M, Goodman L R, Whitehead C, Patounakis G, Scott R T,

Fertil Steril. Mar. 2020 doi: 10.1016/j.fertnstert.2019.09.043

Sperm DNA fragmentation on the day of fertilization is not associated with embryologic or clinical outcomes after IVF/ICSI
Green K A, Patounakis G, Dougherty M P, Werner M D, Scott R T, Franasiak J M,

J Assist Reprod Genet. Jan. 2020 doi: 10.1007/s10815-019-01632-5

Erratum. Worth the wait? Day 7 blastocysts have lower euploidy rates but similar sustained implantation rates as Day 5 and Day 6 blastocysts
Tiegs A W, Sun L, Patounakis G, Scott R T,

Hum Reprod. Dec 1. 2019 doi: 10.1093/humrep/dez219

Embryonic aneuploidy rates are equivalent in natural cycles and gonadotropin-stimulated cycles
Hong K H, Franasiak J M, Werner M M, Patounakis G, Juneau C R, Forman E J, Scott R T,

Fertil Steril. Oct. 2019 doi: 10.1016/j.fertnstert.2019.05.039

Worth the wait? Day 7 blastocysts have lower euploidy rates but similar sustained implantation rates as Day 5 and Day 6 blastocysts
Tiegs A W, Sun L, Patounakis G, Scott R T,

Hum Reprod. 2019 29-Sep. doi: 10.1093/humrep/dez138

The preimplantation genetic testing debate continues: first the hype, then the tension, now the hypertension?
Patounakis G, Hill M J,

Fertil Steril. 2019 Aug. doi: 10.1016/j.fertnstert.2019.04.028

Adjusting for age: is it enough to just say you did it?
Patounakis G, Hill M J,

Fertil Steril. 2019 Feb. doi: 10.1016/j.fertnstert.2018.11.009

Diminished ovarian reserve and poor response to stimulation in patients <38 years old: a quantitative but not qualitative reduction in performance
Morin S J, Patounakis G, Juneau C R, Neal S A, Scott R T, Seli E,

Hum Reprod. 2018 Aug 1. doi: 10.1093/humrep/dey238

Complexities and potential pitfalls of clinical study design and data analysis in assisted reproduction
Patounakis G, Hill M J,

Curr Opin Obstet Gynecol. 2018 Jun. doi: 10.1097/GCO.0000000000000454

Clinical trial registry alone is not adequate: on the perception of possible endpoint switching and P-hacking
Hill M J, Connell M T, Patounakis G,

Hum Reprod. 2018 1-Feb. doi: 10.1093/humrep/dex359

Characterization of reproductive endocrinology and infertility (REI) fellowship applicants: guiding our mentees toward success
Franasiak J M, Kaser D J, Goodman L, Patounakis G, Juneau C, Morin S J, Neal S, Schlaff W, Scott R T,

Fertil Res Pract. 2017 doi: 10.1186/s40738-017-0045-x

Patients with endometriosis have aneuploidy rates equivalent to their age-matched peers in the in vitro fertilization population
Juneau C, Kraus E, Werner M D, Franasiak J M, Morin S J, Patounakis G, Molinaro T A, de Ziegler D, Scott R T,

Fertil Steril. 2017 Aug. doi: 10.1016/j.fertnstert.2017.05.038

Revisiting the progesterone to oocyte ratio
Hill M J, Healy M W, Richter K S, Widra E, Levens E D, DeCherney A H, Patounakis G, Whitcomb B W,

Fertil Steril. 2017 Mar. doi: 10.1016/j.fertnstert.2016.11.019

The slow growing embryo and premature progesterone elevation: Compounding factors for embryo-endometrial asynchrony
Healy M W, Yamasaki M, Patounakis G, Richter K S, Devine K, DeCherney A H, Hill M J,

Hum Reprod. 2017 Feb. doi: 10.1093/humrep/dew296

Does premature elevated progesterone on the day of trigger increase spontaneous abortion rates in fresh and subsequent frozen embryo transfers?
Healy M, Patounakis G, Zanelotti A, Devine K, DeCherney A, Levy M, Hill MJ,

Gynecol Endocrinol. 2017 doi:

Does a frozen embryo transfer ameliorate the effect of elevated progesterone seen in fresh transfer cycles?
Healy MW, Patounakis G, Connell MT, Devine K, DeCherney AH, Levy MJ, Hill MJ,

Fertil Steril. 2016 doi:

Is FMR1 CGG repeat length a predictor of in vitro fertilization stimulation response or outcome?
Banks N, Patounakis G, Devine K, DeCherney AH, Widra EA, Levens ED, Whitcomb BW, Hill MJ,

Fertil Steril. 2016 doi:

Is the effect of premature elevated progesterone augmented by human chorionic gonadotropin versus gonadotropin-releasing hormone agonist trigger?
Connell MT, Patounakis G, Healy MW, DeCherney AH, Devine K, Widra E, Levy MJ, Hill MJ,

Fertil Steril. 2016 doi:

Is the effect of premature elevated progesterone augmented by human chorionic gonadotropin versus gonadotropin-releasing hormone agonist trigger?
Connell MT, Patounakis G, Healy MW, DeCherney AH, Devine K, Widra E, Levy MJ, Hill MJ,

Fertil Steril. 2016 doi:

Multiple thrombophilic single nucleotide polymorphisms lack a significant effect on outcomes in fresh IVF cycles: an analysis of 1717 patients.
Patounakis G, Bergh E, Forman E, Tao X, Lonczak A, Franasiak J M, Treff N, Scott R T,

J Assist Reprod Genet. 2016 doi:

The impact of a prior Cesarean delivery on embryo transfer: a prospective study.
Patounakis G, Ozcan MC, Chason RJ, Norian JM, Payson M, DeCherney AH, Yauger BJ,

Fertil Steril. 2016 doi:

Why abandoning sustained implantation rate may be throwing the baby out with the bathwater
Forman EJ, Franasiak J M, Patounakis G, Scott R T,

Hum Reprod. 2016 doi:

Genetic associations with diminished ovarian reserve: a systematic review of the literature.
Greene AD, Patounakis G, Segars JH,

J Assist Reprod Genet. 2014 doi:

Development of pelvic abscess during pregnancy following transvaginal oocyte retrieval and in vitro fertilization
Patounakis G, Krauss K, Nicholas S, Baxter JK, Rosenblum NG, Berghella V,

Eur J Obstet Gynecol Reprod Biol. 2012 doi:

The p53 codon 72 single nucleotide polymorphism lacks a significant effect on implantation rate in fresh in vitro fertilization cycles: an analysis of 1,056 patients
Patounakis G, Treff N, Tao X, Lonczak A, Scott R T, Frattarelli J,

Fertil Steril. 2009 doi:

Active CMOS array sensor for time-resolved fluorescence detection.
Patounakis G, Shepard KL, Levicky R,

IEEE J Solid-State Circuits. 2006 doi:

Pulse current-mode signalling for nearly speed-of-light intrachip communcations
Jose AP, Patounakis G, Shepard KL,

IEEE J Solid-State Circuits. 2006 doi:

Near Speed-of-Light On-Chip Interconnects Using Pulsed Current-Mode Signaling.
Jose AP, Patounakis G, Shepard KL,

2005 Symposium on VLSI Circuits. 2005 doi:

A Fully Integrated On-Chip DC-DC Conversion and Power Management System.
Patounakis G, Li YW, Shepard KL,

IEEE J Solid-State Circuits. 2004 doi:

High-throughput asynchronous datapath with software-controlled voltage scaling.
Li YW, Patounakis G, Shepard KL, Nowick SM,

IEEE J Solid-State Circuits. 2004 doi:

Asynchronous datapath with software-controlled on-chip adaptive voltage scaling for multirate signal processing applications.
Li YW, Patounakis G, Jose AP, Shepard KL,

2003 IEEE International Symposium on Asynchronous Circuits and Systems. 2003 doi:

Analysis of SAW properties of epitaxial ZnO films grown on R-Al2O3 substrates.
Emanetoglu NW, Patounakis G, Liang S, Gorla CR, Wittstruck R, Lu Y,

IEEE Trans Ultrason Ferroelectr Freq Control. 2001 doi:

Two-step metalorganic chemical vapor deposition growth of piezoelectric ZnO thin film on SiO2/Si substrate.
Muthukumar S, Emanetoglu NW, Patounakis G, Gorla CR, Liang S, Lu Y,

J Vac Sci Technol A. 2001 doi:

Analysis of temperature compensated SAW modes in ZnO/SiO2/Si multilayer structures
Emanetoglu NW, Patounakis G, Muthukumar S, Lu Y,

2000 IEEE Ultrasonics Symposium. 2000 doi:

Virtual Reality Training for the Diagnosis of Prostate Cancer.
Burdea G, Patounakis G, Popescu V, Weiss RE ,

VRAIS '98 Proceedings of the Virtual Reality Annual International Symposium. 1998 doi:

Presentaciones

Tiegs AW Tao X Zhan Y Whitehead CV Hanson BM Kim JG Osman EK Seli E Patounakis G Gutmann J Castelbaum AJ Kim T Chaim Jalas O-77 TRANSFER OUTCOMES OF EMBRYOS WITH PREIMPLANTATION GENETIC TESTING FOR ANEUPLOIDY (PGT-A) DIAGNOSES OF UNDETERMINED REPRODUCTIVE POTENTIAL: RESULTS FROM A PROSPECTIVE, BLINDED, MULTI-CENTER NON-SELECTION STUDY. Presented at 76th American Society of Reproductive Medicine Scientific Congress, Virtual congress, October 17-21,2020

Tiegs A Tao X Whitehead Neal S Osman E Kim J Hanson B Seli E Patounakis G Gutmann JN Castelbaum AJ Scott RT O-084 A multi-center, prospective, blinded, non-selection study evaluating the predictive value (PV) of an aneuploid preimplantation genetic testing for aneuploidy (PGT-A) diagnosis and impact of biopsy. Presented at the 67th Annual Meeting of the Society for Reproductive Investigation, Vancouver ,Canada, March 10-14, 2020

Kim G Patounakis G Juneau C Morin SJ Neal SA Tiegs AW Osman EK Hanson BM Scott RT P-268 ABC TRIAL: BODY MASS INDEX AND PERCENTAGE BODY FAT ARE NOT DIFFERENT IN POSITIVE PREDICTIVE VALUE OF MISCARRIAGE OR PRETERM DELIVERY IN PATIENTS UNDERGOING IVF. Presented at the 35th annual meeting of the European Society of Human Reproduction and Embryology, Vienna, Austria, 14-16 October 2019

Neal SA Morin SJ Werner MD Gueye N Pirtea P Patounakis G Scott RT Goodman LR O-214 THREE-DIMENSIONAL ULTRASOUND DIAGNOSIS OF ADENOMYSIS IS NOT ASSOCIATED WITH DIMINISHED LIVE BIRTH FOLLOWING SINGLE THAWED EUPLOID BLASTOCYST TRANSFER: A PROSPECTIVE COHORT STUDY. Presented at the 35th annual meeting of the European Society of Human Reproduction and Embryology, Vienna, Austria, 14-16 October 2019

Tiegs AW Tao X Whitehead CR Neal SA Osman EK Kim G Hanson BM Seli E Patounakis G Gutmann J Castlebaum A O-74 DOES PREIMPLANTATION GENETIC TESTING FOR ANEUPLOIDY (PGT-A) HARM EMBRYOS? NO—A MULTI-CENTER, PROSPECTIVE, BLINDED, NON-SELECTION STUDY EVALUATING THE PREDICTIVE VALUE OF AN ANEUPLOID DIAGNOSIS AND IMPACT OF BIOPSY. Presented at the 35th annual meeting of the European Society of Human Reproduction and Embryology, Paris, France, 14-16 October 2019

Kim G Morin SJ Patounakis G Juneau C Neal SA Abc trial: appraisal of body content. Frozen embryo cycles are not impacted by the negative effects of obesity seen in fresh cycles. Presented at the 65th Annual Meeting of the Society for Reproductive Investigation, San Diego,CA,USA, October 6-10, 2018

Morin SJ Patounakis G Juneau CR Neal SA Scott RT Seli E Quantity versus quality: do patients with diminished ovarian reserve (DOR) and poor response to stimulation also exhibit poor blastulation and increased aneuploidy . , , October 28-November 1,2017

Investigación en Fertilidad

NUESTROS INVESTIGADORES

Biografía

Formación

Honores y reconocimientos

Publicaciones

Presentaciones