FIV Clinica
La asistencia médica a los pacientes que se someten a tratamientos de FIV no ha dejado de ser un área de principal interés para los investigadores. Se debe comenzar por un diseño adecuado del tratamiento de los pacientes con el fin de determinar áreas de investigación como el sistema inmunitario, la importancia del microbioma, factores dietéticos, el índice de masa corporal, factores masculinos, entre otros, que pueden influir en el éxito o fracaso del tratamiento.
Este proceso se debe continuar durante todo el tratamiento, con el fin de ajustar la medicación o utilizar suplementos que puedan ayudar a aumentar las probabilidades de éxito del tratamiento, dado que son muchas las circunstancias que rodean a un tratamiento de FIV, tanto en ciclos estimulados como en ciclos con gametos o embriones crioconservados. Además, es muy importante conocer el impacto psicológico que todo proceso de FIV conlleva para encontrar la mejor manera, ofrecer los mejores cuidados y reducir al máximo el impacto emocional.
Investigadores trabajando en este área
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Públicaciones en este área
- Diminished ovarian reserve and poor response to stimulation in patients <38 years old: a quantitative but not qualitative reduction in performance.
Morin SJ Patounakis G Juneau CR Neal SA Scott RT Seli E
Hum Reprod. 2018 Jul 11. doi: 10.1093/humrep/dey238. [Epub ahead of print]
- Introduction: IVF's 40th world birthday.
Niederberger C Pellicer A
Fertil Steril. 2018 Jul 1;110(1):4. doi: 10.1016/j.fertnstert.2018.05.017.
- Forty years of IVF.
Niederberger C Pellicer A Cohen J Gardner DK Palermo GD Neill CL Chow S Rosenwaks Z Cobo A Swain JE Schoolcraft WB Frydman Bishop LA Aharon D Gordon C New E Decherney A Tan SL Paulson RJ Goldfarb JM Brännström M Donnez JSilber S Dolmans MM Simpson JL Handyside AH Munné S Eguizabal C Montserrat N Izpisua Belmonte JC Trounson A Simon C Tulandi T Giudice LC Norman RJ Hsueh AJ Sun Y Laufer N Kochman R Eldar-Geva T Lunenfeld B Ezcurra D Hooghe T Fauser BC Tarlatzis B Meldrum D Casper R Fatemi H Devroey P Galliano D
Fertil Steril. 2018 Jul 15;110(2):185-324.e5. doi: 10.1016/j.fertnstert.2018.06.005. Review.
- A cost-effectiveness modelling evaluation comparing a biosimilar follitropin alfa preparation with its reference product for live-birth outcome in Germany, Italy and Spain.
Gizzo S Ferrando M Lispi M Ripellino C Cataldo N Bühler K
J Med Econ. 2018 Aug 16:1-13. doi: 10.1080/13696998.2018.1511567. [Epub ahead of print]
- Current status and future prospects of noninvasive preimplantation genetic testing for aneuploidy.
Fragouli E Wells D
Fertil Steril. 2018 Aug;110(3):408-409. doi: 10.1016/j.fertnstert.2018.04.021. No abstract available.
- The Effect of Dose Adjustments in a Subsequent Cycle of Women With Suboptimal Response Following Conventional Ovarian Stimulation.
Drakopoulos P Santos-Ribeiro S Bosch E García-Velasco JA Blockeel C Romito A Tournaye H Polyzos NP
Front Endocrinol (Lausanne). 2018 Jul 23;9:361. doi: 10.3389/fendo.2018.00361. eCollection 2018.
- Celiac disease is not more prevalent in patients undergoing in vitro fertilization and does not affect reproductive outcomes with or without treatment: a large prospective cohort study.
Juneau CR Franasiak JM Goodman L Marin D Scott K Morin SJ Neal SA Juneau JE Scott RT
Fertil Steril. 2018 Aug;110(3):437-442. doi: 10.1016/j.fertnstert.2018.03.030.
- Conventional versus minimal ovarian stimulation: an intra-patient comparison of ovarian response in poor-responder women according to Bologna Criteria.
Labarta E Marin D Remohí J Bosch E
Reprod Biomed Online. 2018 Aug 23. pii: S1472-6483(18)30398-5. doi: 10.1016/j.rbmo.2018.07.007. [Epub ahead of print]
- Cumulative live birth rates according to the number of oocytes retrieved after the first ovarian stimulation for in vitro fertilization/intracytoplasmic sperm injection: a multicenter multinational an
Polyzos NP Drakopoulos P Parra J Pellicer A Santos-Ribeiro S Tournaye H Bosch E García-Velasco JA
Fertil Steril. 2018 Sep;110(4):661-670.e1. doi: 10.1016/j.fertnstert.2018.04.039.
- Infertile Couples Prefer Twins: Analysis of Their Reasons and Clinical Characteristics Related to This Preference.
Mendoza R Jáuregui T Díaz-Nuñez M De la Sota M Hidalgo A Ferrando M Martínez-Indart L Expósito A Matorras R
J Reprod Infertil. 2018 Jul-Sep;19(3):167-173.
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Presentaciones en esta área
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Lara EE Franasiak JM Devesa-Peiro A Martin M Florensa M Lopez M Díaz-Gimeno P Pellicer A 24,25(oh)2d3: a novel accurate indicator of ovarian vitamin d status in women at reproductive age Presented at the 74th Scientific Congress & Expo of the American Society for Reproductive Medicine
ASRM 2018
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Fernandez-Sanchez M Visnova H Yuzpe A Klein BM Mannaerts B Arce JC
Individualization of the starting dose of gonadotropin reduces the overall ohss risk and the need of preventive cumulative data over three
Presented at the 74th Scientific Congress & Expo of the American Society for Reproductive Medicine
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Pirtea P Marin D Sun L Hong K Zhan Y Tao X Scott RT
Gonadotrophin receptor polymorphisms (fshr n680s and lhcgr n312s) are not of clinical outcome and live birth in ivf cycles
Presented at the 74th Scientific Congress & Expo of the American Society for Reproductive Medicine
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Kim G Morin SJ Patounakis G Juneau C Neal SA
Abc trial: appraisal of body content. Frozen embryo cycles are not impacted by the negative effects of obesity seen in fresh cycles
Presented at the 74th Scientific Congress & Expo of the American Society for Reproductive Medicine
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Dolitsky N Neal SA Olcha M Hong K Werner MD Morin SJ Tiegs W Sun L Scott RT
Initial serum human chorionic gonadotropin levels predict live birth outcomes following frozen embryo transfer with and without preimplantation genetic testing for aneuploidy (pgt-a)
Presented at the 74th Scientific Congress & Expo of the American Society for Reproductive Medicine
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Labarta E Mariani Paolelli S Vidal C Giles J Marzal A Bellver J Cruz F Olmo I Alama P Celada P Bosch E
Impact of serum progesterone levels on the day of embryo transfer in artificial endometrial preparation cycles on the ongoing pregnancy rate. An interim analysis
Presented at the 74th Scientific Congress & Expo of the American Society for Reproductive Medicine
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Polyzos N Drakopoulos P Tournaye H Schiettecatte J Anckaert E Donner H Bobba G Miles G Verhagen-Kamerbeek W Bosch E
Estradiol and progesterone in in vitro fertilization (esprit): evaluation of the third versus second generation estradiol and progesterone elecsys assays
Presented at the 74th Scientific Congress & Expo of the American Society for Reproductive Medicine
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Bosch E Labarta E Zuzuarregui J Iliodromiti S Nelson SM
Prediction of ovarian response with an automated amh assay (elecsys) in gnrh antagonist cycles
Presented at the 74th Scientific Congress & Expo of the American Society for Reproductive Medicine
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Bosch E Howles C
No difference in clinical outcomes using follitropin alfa (biosimilar) compared to follitropin alfa or follitropin beta for controlled ovarian stimulation (cos) in oocyte donation-recipient cycles
Presented at the 74th Scientific Congress & Expo of the American Society for Reproductive Medicine
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Del Gallego R Alegre L Cnaani T Shnizer S Remohí J Meseguer M Clinical validation of a non-invasive embryo selection algorithm combining time-lapse morphokinetics and the oxidative status of spent embryo culture media. Presented at the 34rd annual meeting of the European Society of Human Reproduction and Embryology
ESHRE 2018
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Alecsandru D Iglesias C Pacheco A Barrio A Garrido N Garcia Velasco J
HLA-C haplotypes distribution among gametes donors in our population
Presented at the 34rd annual meeting of the European Society of Human Reproduction and Embryology
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Herrer Saura R Sciorio R Esbert M Pickering S Thong J Meseguer M
Blastocysts collapse as an embryo marker of low implantation potential a Time-Lapse study
Presented at the 34rd annual meeting of the European Society of Human Reproduction and Embryology
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Liñán A Bayram A Arnanz A Elkhatib I Rubio C Rupali C Garrido N Fatemi H Lawrenz B
Comparison of mitochondrial DNA content in euploid and aneuploid embryos at cleavage stage and blastocyst stage with NGS
Presented at the 34rd annual meeting of the European Society of Human Reproduction and Embryology
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Castillo LM Buigues A Pellegrini L Rossi V Klinger F Pellicer A Herraiz S
LH gonadoprotection against ovarian damage induced by alkytaing drugs in adult mouse ovaries.
Presented at the 34rd annual meeting of the European Society of Human Reproduction and Embryology
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Staicu FD Martinez-Soto JC Matas C
Protein kinase A modulation by nitric oxide during human sperm capacitation
Presented at the 34rd annual meeting of the European Society of Human Reproduction and Embryology
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Elkhatib I Lawrenz B Linan A Arnanz A Bayram A Fatemi H
Comprehensive comparison of Trophectoderm (TE) and Inner cell mass (ICM) by Next Generation Sequencing (NGS)
Presented at the 34rd annual meeting of the European Society of Human Reproduction and Embryology
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Labarta E Herraiz S De Los Santos MJ Marzal A Jose Escribá M Buigues A Pellicer A
Autologous mitochondrial transfer (AugmentSM) as a complementary technique to ICSI to improve oocyte and embryo quality in IVF patients. A Randomized Pilot Study.
Presented at the 34rd annual meeting of the European Society of Human Reproduction and Embryology
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Rivera R Sota N Meseguer M Dominguez F Remohí J Garrido N
Differential sperm proteomic profile between sperm samples achieving pregnancy or not in intracytoplasmic sperm injection (ICSI) cycles in oocyte donation program
Presented at the 34rd annual meeting of the European Society of Human Reproduction and Embryology
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Sakkas D Atkinson L Borini A Bosch E Bryce C Cattoli M Finet de Bantel A French B Gaitonde S Gerris J Granger S Grzegorczk-Martin V Howles C Somers S Alper M
Can "patient-friendly" salivary hormone measurements replace serum monitoring of IVF
Presented at the 34rd annual meeting of the European Society of Human Reproduction and Embryology
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Morin SJ Tao X Bedard J Landis J Zhan Y Scott RT Seli E Epigenetic Clock Model of Somatic Aging Accurately Predicts Chronologic Age When Applied to White Blood Cells But Not Cumulus Cells in Reproductive Age Women Presented at the 65th Annual Meeting of the Society for Reproductive Investigation
SRI 2018
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Perez S Salsano S Quiñonero A Dominguez F
Phytoestrogens (Soy-Derived Metabolites) May Act Like Endometrial Disruptors Altering Decidualization of Human Endometrial Stromal Cells
Presented at the 65th Annual Meeting of the Society for Reproductive Investigation
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Tao X Zhan Y Scott K Scott RT Seli E
DNA methylation is associated with ploidy status, delayed blastulation, and patient age in human embryos
Presented at the 65th Annual Meeting of the Society for Reproductive Investigation
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Alegre L Palma AE Marcos JJ Albert C Del Gallego R Pellicer A Meseguer M Time-lapse technology combined with a novel automated analysis method for embryo selection; clinical validation Presented at the 73rd annual meeting of the American Society of Reproductive Medicine
ASRM 2017
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Basile N Insua MF Cobo A Tejera A Pellicer A Meseguer M
The difference in delivery rates and number of neonates between time-lapse systems and standard incubators changes depending on the number and the stage of the embryos being transferred
Presented at the 73rd annual meeting of the American Society of Reproductive Medicine
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Bedard JL Jalas C Juneau CR Zimmerman RS Scott RT
Sustained implantation rate is not impacted by increasing fragile X premutation allele size
Presented at the 73rd annual meeting of the American Society of Reproductive Medicine
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Beltran D Vásquez V De Los Santos MJ
Do the environmental pollutants affect the mitochondrial content of human embryos?
Presented at the 73rd annual meeting of the American Society of Reproductive Medicine
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Cobo A Meseguer M Coello A Sanchez E Garcia Velasco J Remohí J Pellicer A
Estimation of reproductive success according to age, number of oocytes and etiology in elective or oncological fertility preservation (FP) patients
Presented at the 73rd annual meeting of the American Society of Reproductive Medicine
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Coello A Sanchez E Campos P Vallejo B Meseguer M Cobo A
Oocyte dysmorphisms are not associated with post warming survival, fertilization and embryo development in own oocytes vitrification cycles
Presented at the 73rd annual meeting of the American Society of Reproductive Medicine
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Colombo S Franasiak JM Kaser DJ Molinaro T Bergh PA
Significance of endometrial lining decrease after progesterone start in synthetic frozen embryo transfer (FET) cycles
Presented at the 73rd annual meeting of the American Society of Reproductive Medicine
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Eccles JM Iturriaga A Garnsey HM Landis LN Zhan Y Scott RT Treff N Zimmerman RS
Experience with a targeted next generation sequencing (TNGS) platform for comprehensive chromosome screening (CCS) on over 16 000 embryo biopsies
Presented at the 73rd annual meeting of the American Society of Reproductive Medicine
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Esbert M Pachecho A Reis Soares S Amoros D Meseguer M
Oocytes from healthy donors delay embryo cleavage to repair DNA
Presented at the 73rd annual meeting of the American Society of Reproductive Medicine
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Esbert M Marconetto A Reis Soares S Quera M Molina J Florensa M Ballesteros A Meseguer M
Does the blastocyst collapse respond to a biological need? The analysis of 1,952 embryos by time-lapse can give an answer
Presented at the 73rd annual meeting of the American Society of Reproductive Medicine
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Adamson GD De Mouzon J Dyer S Chambers G Ishihar O ICMART World Report 2013 Presented at the 33rd annual meeting of the European Society of Human Reproduction and Embryology
ESHRE 2017
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Alecsandru D Pacheco A Garrido N Barrio A Aparicio P Pellicer A Garcia Velasco J
Live birth rate after oocyte donation is influenced by donor HLA-C: one step beyond conventional markers of success
Presented at the 33rd annual meeting of the European Society of Human Reproduction and Embryology
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Alegre L Arrones S Shnizer S Tzali C Beltrán D De los Santos MJ Pellicer A Meseguer M
Clinical validation of a noninvasive biomarker for embryo selection based on thermochemiluminescence analysis of the embryo spent culture medium
Presented at the 33rd annual meeting of the European Society of Human Reproduction and Embryology
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Alegre L Aparicio-Ruíz B Loewke K Arrones S Albert C Remohí J Meseguer M
Clinical validation of a new automated analysis for embryo selection based on time-lapse technology
Presented at the 33rd annual meeting of the European Society of Human Reproduction and Embryology
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Calonge M Garrido N Cobo A Gonzalez-Valdes F Morbeck D Requena A Troncoso C
Quantifying the parameters affecting the success of egg donor program: A predictive model and optimization tool
Presented at the 33rd annual meeting of the European Society of Human Reproduction and Embryology
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Cerrillo M Cruz M Ferrando R García Velasco JA
Freeze-all strategy in endometriosis patients - a new indication?
Presented at the 33rd annual meeting of the European Society of Human Reproduction and Embryology
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Dahiya M Bhatia M Egbert S
A systematic review and narrative report of the profound psycho-socio-cultural consequences of the growing burden of infertility in developing countries
Presented at the 33rd annual meeting of the European Society of Human Reproduction and Embryology
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Diaz-Gimeno P Sebastian-Leon P Remohí J Garrido N Pellicer A
New transcriptomic insight improves endometrial Recurrent Implantation Failure (RIF) diagnosis and distinguishes clearly between a displaced and a disrupted Window Of Implantation (WOI)
Presented at the 33rd annual meeting of the European Society of Human Reproduction and Embryology
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García Camuñas N Vázquez S Pellicer N Jesica S Garcia Belda A Andres M Herraiz S Pellicer A Díaz García C
Fertility preservation. Anatomopathological analysis of ovarian cortex metastasis in a large cohort of patient undergoing fertility preservation through ovarian cortex cryopreservation
Presented at the 33rd annual meeting of the European Society of Human Reproduction and Embryology
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Gianzo M Larreategui Z Muñoa-Hoyos I Urizar-Arenaza I Irazusta J Subiran N
The (Pro)renin receptor is expressed in human sperm cells and is related to sperm quality and embryo development
Presented at the 33rd annual meeting of the European Society of Human Reproduction and Embryology
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Díaz-Gimeno P Ruiz-Alonso M Sebastián-León P Singh V Pellicer A Valbuena D Simón C Improvement of the endometrial receptivity signature reveals a possible maternal origin of biochemical pregnancies Presented at the 64th Annual Meeting of the Society for Reproductive Investigation
SRI 2017
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Herraiz S Buigues A Romeu M Díaz-García C Hsueh A Pellicer A
Infusion Of Human Bone Marrow-Derived Stem Cells Improved Ovarian Function In Chemotherapy-Damaged Ovaries In Mice
Presented at the 64th Annual Meeting of the Society for Reproductive Investigation
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Herraiz S Romeu M Martínez S Díaz-García C Solves P Gómez I Martínez J Anna Buigues Simón C Galliano D Pellicer A
Two Live Birth After Stem Cell Ovarian Auto-Transplantation In PR Women
Presented at the 64th Annual Meeting of the Society for Reproductive Investigation
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Vilella F Behr B Reddy V Wang W Navarro R Jiménez J Quake S C Simón
Maternal endometrial hsa-miR-30d is taken up by the human blastocyst and induces transcriptional modifications
Presented at the 64th Annual Meeting of the Society for Reproductive Investigation