
Manuel Fernández-Sánchez, M.D., Ph.D.
IVI Sevilla
Biografía
Manuel Fernández-Sánchez is the director of IVI Sevilla, Associate Professor of Assisted Reproductive Technology and Gene Therapy in Molecular Biology and Biochemical Engineering in Department, Pablo Olavide University, Sevilla, and Associate Professor of Biomedicine and Gynecology in Faculty of Medicine, University of Sevilla. Dr. Fernandez-Sanchez, trained at CHI Andre Gregoire Hospital of Paris (France), and The Queen’s Medical Research Institute in Edinburgh (the United Kingdom). He also obtained a Degree of Statistics and Research Methodology at the University Autónoma of Barcelona, he completed a Master of Human Reproduction at University Rey Juan Carlos of Madrid and an Executive Master in Management and Administration of Health Institutions in Esade Business School, Ramon Llul University, Madrid.
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Formación
MD | University of Sevilla (1996) |
Residency | University of Seville (2002) |
Fellowship | CHI Andre Gregoire Hospital of Paris (2002) |
M.Sc. in Statistics and Research Methodology | Autonomous University of Barcelona (2008) |
Fellowship | The Queen’s Medical Research Institute in Edinburgh (2009) |
MSc in Human Reproduction | Rey Juan Carlos University of Madrid (2009) |
Ph.D. | University of Valencia (2012) |
M.Sc. in Management and Administration of Health Institutions | Ramón Llull University (2015) |
Honores y reconocimientos
Illustrious doctor by the Royal Medicine Academy of Seville | 2015 |
1st Award of the Royal Medicine Academy of Seville | 2008 |
1st Award of the Royal Medicine Academy of Seville | 2006 |
3rd Merck-Serono Award, Salud 2000 Foundation. Clinical investigation Area | 2006 |
1st Scientific Award of the Seville Medical Society | 2006 |
Publicaciones
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Female infertility is associated with an altered expression of the neurokinin B/neurokinin B receptor and kisspeptin/kisspeptin receptor systems in ovarian granulosa and cumulus cells.
Blasco V Pinto FM Fernández-Atucha A González-Ravina C Fernández-Sánchez M Candenas L
Fertil Steril. 2020 Aug 15:S0015-0282(20)30442-8. doi: 10.1016/j.fertnstert.2020.05.006. Online ahead of print. -
Sam68 mediates leptin signaling and action in human granulosa cells: possible role in leptin resistance in PCOS.
Vilariño-García T Pérez-Pérez A Santamaría-López E Prados N Fernández-Sánchez M Sánchez-Margalet V
Endocr Connect. 2020 Jun;9(6):479-488. doi: 10.1530/EC-20-0062. -
Effect of Group Embryo Culture under Low-Oxygen Tension in Benchtop Incubators on Human Embryo Culture: Prospective, Randomized, Controlled Trial.
Ruíz M Santamaría-López E Blasco V Hernáez MJ Caligara C Pellicer A Fernández-Sánchez M Prados N
Reprod Sci. 2020 Jan 28. doi: 10.1007/s43032-020-00150-5. [Epub ahead of print] -
Is it safe and effective to maintain the vaginal pessary without removing it for 2 consecutive years?
Miceli A Fernández-Sánchez M Polo-Padillo J Dueñas-Diez JL
Int Urogynecol J 2020 -
Female infertility is associated with an altered expression of the neurokinin B/neurokinin B receptor and kisspeptin/kisspeptin receptor systems in ovarian granulosa and cumulus cells.
Blasco V Pinto FM Fernández-Atucha A González-Ravina C Fernández-Sánchez M Candenas L
Fertil Steril. 2020 Aug 15:S0015-0282(20)30442-8. doi: 10.1016/j.fertnstert.2020.05.006. Online ahead of print. -
Sam68 mediates leptin signaling and action in human granulosa cells: possible role in leptin resistance in PCOS.
Vilariño-García T Pérez-Pérez A Santamaría-López E Prados N Fernández-Sánchez M Sánchez-Margalet V
Endocr Connect. 2020 Jun;9(6):479-488. doi: 10.1530/EC-20-0062. -
Effect of Group Embryo Culture under Low-Oxygen Tension in Benchtop Incubators on Human Embryo Culture: Prospective.
Ruíz M Santamaría-López E Blasco V Hernáez MJ Caligara C Pellicer A Fernández-Sánchez M Prados N
Reprod Sci. 2020 Jan 28. doi: 10.1007/s43032-020-00150-5. [Epub ahead of print] -
Tachykinins and Kisspeptins in the Regulation of Human Male Fertility.
Blasco V Pinto FM González-Ravina C Santamaría-López E Candenas L Fernández-Sánchez M
J Clin Med. 2019 Dec 31;9(1). pii: E113. doi: 10.3390/jcm9010113. Review. -
Deregulation of miR-324/Kiss1/kisspeptin in early ectopic pregnancy: Mechanistic findings with clinical and diagnostic implications.
Romero-Ruiz A Avendaño MS Dominguez F Lozoya T Molina-Abril H Sangiao-Alvarellos S Gurrea M Lara-Chica M Fernandez-Sanchez M Torres E Perdices-Lopez C Abbara A Steffani L Calzado MA Dhillo WS Pellicer A Tena-Sempere M
Am J Obstet Gynecol. 2019 Jan 29. pii: S0002-9378(19)30282-0. doi: 10.1016/j.ajog.2019.01.228. [Epub ahead of print -
Individualization of the starting dose of follitropin delta reduces the overall OHSS risk and/or the need for additional preventive interventions: cumulative data over three stimulation cycles.
Fernández-Sánchez M Visnova H Yuzpe A Klein BM Mannaerts B Arce JC; ESTHER-1 and ESTHER-2 Study Group
Reprod Biomed Online. 2018 Dec 23. pii: S1472-6483(18)30661-8. doi: 10.1016/j.rbmo.2018.12.032. [Epub ahead of print]
- Ferroportin mRNA is down-regulated in granulosa and cervical cells from infertile women.
Moreno-Navarrete JM, López-Navarro E, Candenas L, Pinto F, Ortega FJ, Sabater-Masdeu M, Fernández-Sánchez M, Blasco V, Romero-Ruiz A, Fontán M, Ricart W, Tena-Sempere M, Fernández-Real JM.
Fertil Steril, 107 (1): 236-242, 2017. - Individualized versus conventional ovarian stimulation for in vitro fertilization: a multicenter, randomized, controlled, assessor-blinded, phase 3 noninferiority trial.
Nyboe Andersen A, Nelson SM, Fauser BC, García-Velasco JA, Klein BM, Arce JC; ESTHER-1 study group.
Fertil Steril, 107 (2): 387-396.e4, 2017. - Insulin and Leptin Signaling in Placenta from Gestational Diabetic Subjects.
Pérez-Pérez A, Guadix P, Maymó J, Dueñas JL, Varone C, Fernández-Sánchez M, Sánchez-Margalet V.
Horm Metab Res, 48 (1): 62-69, 2016. - Expression of Tachykinins and Tachykinin Receptors and Interaction with Kisspeptin in Human Granulosa and Cumulus Cells.
García-Ortega J, Pinto FM, Prados N, Bello AR, Almeida TA, Fernández-Sánchez M, Candenas L.
Biol Reprod, 94 (6): 124, 2016. - Increased Expression of Aquaporin 9 in Trophoblast From Gestational Diabetic Patients.
Vilariño-García T, Pérez-Pérez A, Dietrich V, Fernández-Sánchez M, Guadix P, Dueñas JL, Varone CL, Damiano AE, Sánchez-Margalet V.
Horm Metab Res, 48 (8): 535-539, 2016. - Elective single versus double embryo transfer: live birth outcome and patient acceptance in a prospective randomised trial.
Prados N, Quiroga R, Caligara C, Ruiz M, Blasco V, Pellicer A, Fernández-Sánchez M.
Reprod Fertil Dev, 27 (5): 794-800, 2015. - Monozygotic twinning after assisted reproductive technologies: a case report of asymmetric development and incidence during 19 years in an international group of in vitro fertilization clinics.
Tocino A, Blasco V, Prados N, Vargas MJ, Requena A, Pellicer A, Fernández-Sánchez M.
Fertil Steril, 103 (5): 1185-1189, 2015. - Follicular and endocrine dose responses according to anti-Mullerian hormone levels in IVF patients treated with a novel human recombinant FSH (FE 999049).
Bosch E, Nyboe Andersen A, Barri P, García-Velasco JA, de Sutter P, Fernández-Sánchez M, Visnova H, Klein BM, Mannaerts B, Arce JC.
Clin Endocrinol, 83 (6): 902-912, 2015.
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Presentations
- Simon C Gómez C Cabanillas S Vladimirov IK Castillón G Giles J Boynukalin FK Findikli N Ortega I Vidal C Izquierdo A Portela S Frantz N Taguchi S Labarta E Colucci F Mackens S Santamaría X Muñoz E Barrera SG Fernandez-Sanchez M O-134 IN VITRO FERTILIZATION WITH PERSONALIZED BLASTOCYST TRANSFER VERSUS FROZEN OR FRESH BLASTOCYST TRANSFER: A MULTICENTER, RANDOMIZED CLINICAL TRIAL. Presented at the 35th annual meeting of the European Society of Human Reproduction and Embryology, Vienna, Austria, 14-16 October 2019
- Fernandez-Sanchez M Visnova H Yuzpe A Klein BM Mannaerts B Arce JC Individualization of the starting dose of gonadotropin reduces the overall ohss risk and the need of preventive cumulative data over three. Presented at the 34rd annual meeting of the European Society of Human Reproduction and Embryology, Barcelona, Spain, October 6-10, 2018
- González-Ravina C Cruz M Rubio C Fernández-Sánchez M Oquiñena E Ferrando R Requena A Polymorphic chromosome variants, human inversions, and their functional consequences in male infertility. , , July 2-5 ,2017
- Rubio Lluesa C Cruz M González-Ravina C Fernández-Sánchez M Oquiñena E Requena A Polymorphism on chromosome 21 does not affect ovarian reserve but clinical outcomes after in vitro fertilization treatments. , , July 2-5 ,2017
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