María Cruz, Ph.D.

Clinical Embryologist at IVI Madrid

IVI Madrid

María Cruz, Ph.D.


Dr. María Cruz, is a clinical embryologist at IVI Madrid and a faculty for the Master’s Degree in Biology and Technology Applied to Assisted Human Reproduction at the European University of Madrid. She obtained her B.S.c in in Biological Sciences at the Complutense University of Madrid and received her Ph.D. from University of Valencia. Dra. Cruz also obtained a Master’s Degree in Biotechnology of Assisted Human Reproduction and a course of Research Methodology applied to Design and Statistics in Health sciences from the Autonoma University of Barcelona. Her research interests include Endocrinology, time-lapse analysis and genetic polymorphisms.


B.S.c in in Biological Sciences Complutense University of Madrid
Ph. D University of Valencia
Master’s Degree in Biotechnology of Assisted Human Reproduction
University of Barcelona


  • Dual triggering with gonadotropin-releasing hormone agonist and standard dose human chorionic gonadotropin in patients with a high immature oocyte rate.
    Fabris A, Cruz M, Legidos V, Igelsias C, Muñoz M, García-Velasco JA.
    Reprod Sci, 24:1221-1225, 2017.

  • Exccesive age-related decline in functional ovarian reserve in infertile women: prospective cohort of 15500 women.
    Iliodromiti S, Iglesias C, Messow CM, Cruz M, García-Velasco JA, Nelson SM.
    J Clin Endocrinol Metab, 10:3548-3554, 2016.

  • Ethnicity is an independent predictor of IVF-ICSI outcome: a study of 5549 cycles in Spain and India.
    Patel A, Patel J, Cruz M, Gupte-Shah A, García-Velasco JA, Banker MR.
    Gynecol Endocrinol, 32:819-822, 2016.

  • Type of gonadotropin during controlled ovarian stimulation affects the endocrine profile in follicular fluid and apoptosis rate in cumulus cells.
    Requena A, Cruz M, Agudo A, Pacheco A, García-Velasco JA.
    Eur J Obstet Gynecol Reprod Biol, 197:142-146, 2016.

  • Assisted reproductive techniques after fertility-sparing treatments in gynaecological cancers.
    Zapardiel I, Cruz M, Diestro MD, Requena A, García-Velasco JA
    Hum Reprod Update, 22, 2016.

  • Ongoing pregnancy rates in intrauterine insemination are affected by late follicular-phase progesterone levels.
    Requena A, Cruz M, Pacheco A, García-Velasco JA.
    Fertil Steril, 104:879-883, 2015.

  • Impact of circulating levels of total and bioavailable serum vitamin D on pregnancy rate in egg donation recipients.
    Fabris A, Pacheco A, Cruz M, Puente JM, Fatemi H, García-Velasco JA.
    Fertil Steril, 102:1608-1612, 2014.

  • Sucessful twin delivery following transmyometrial embryo transfer in a patient with a false uterine cavity.
    Muñoz M, Galindo N, Pérez-Cano I, Cruz M, García-Velasco JA.
    Reprod Biomed Online, 28:137-140, 2014.

  • Endocrine profile following stimulation with recombinant follicle stimulating hormone and luteinizing hormone versus highly purified human menopausal gonadotropin.
    Requena A, Cruz M, Ruiz F, García-Velasco JA.
    Reprod Biol Endocrinol, 12:10, 2014.

  • High progesterone levels in women with high ovarian response do not affect clinical outcomes: a retrospective cohort study.
    Requena A, Cruz M, Bosch E, Meseguer M, García-Velasco JA.
    Reprod Biol Endocrinol 12:69, 2013.
    Oocyte insemination techniques are related to alterations of embryo developmental timing in an oocyte donation model.
    Cruz M, Garrido N, Gadea B, Muñoz M, Pérez-Cano I, Meseguer M.
    Reprod Biomed Online, 27-367-375, 2013.

  • Is morphokinetic analysis the answer?
    Aparicio B, Cruz M, Meseguer M.
    Reprod Biomed Online, 27:654-663, 2013.

  • The type pf GnRH analogue used during controlled ovarian stimulation influences early embryo developmental kinetics: a time-lapse study.
    Muñoz M, Cruz M, Humaidan P, Garrido N, Pérez-Cano I, Meseguer M
    Eur J Obstet Gynecol Reprod Biol, 168:167-172, 2013.

  • Evaluation of the degree of satisfaction in oocyte donors using sustained-release FSH corifollitropin alfa.
    Requena A, Cruz M, Collado D, Izquierdo A, Ballesteros A, Muñoz M, García-Velasco JA.
    Reprod Biomed Online, 26:253-259, 2013.

  • Timing of cell división in human cleavage-stage embryos is linked with blastocyst formation and quality.
    Cruz M, Garrido N, Herrero J, Pérez-Cano I, Muñoz M, Meseguer M
    Reprod Biomed Online, 25:371-381, 2012.

  • Embryo incubation and selection in a time-lapse monitoring system improves pregnancy outcome compared with a standard incubator: a retrospective cohor study.
    Meseguer M, Rubio I, Cruz M, Basile N, Marcos J, Requena A.
    Fertil Steril, 98:1481-1489, 2012.

  • Dose of recombinant FSH and oestradiol concentration on day of HCG affect embryo developmental kinetics.
    Muñoz M, Cruz M, Humaidan P, Garrido N, Pérz-Cano I, Meseguer M.
    Reprod Biomed Online, 25:382-389, 2012.

  • Embryo quality, blastocyst and ongoing pregnancy rates in oocyte donation patients whose embryos were monitored by time-lapse imaging.
    Cruz M, Gadea B, Garrido N, Pedersen KS, Martínez M, Pérez-Cano I, Muñoz M, Meseguer M.
    J Assist Reprod Genet, 28:569-573, 2011.

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