
Francisco Dominguez, Ph.D.
Laboratory Manager & Endometrial Receptivity and Embryonic Competence Research Group Leader at the IVI Foundation Research Department
FIVI Valencia
Francisco Dominguez, Ph.D.
Biografía
Dr. Dominguez is a full-time head investigator at FIVI-INCLIVA through a type I Miguel Servet contract and laboratory manager for the IVI Foundation Research department. He completed his Bachelor’s degree in Biology at the University of Valencia in 1998, and obtained his doctorate degree “cum laude” in 2003 in the Pediatrics, Obstetrics and Gynaecology Department of the University of Valencia School of Medicine. He did his post-doctoral training at the CNIC (Spanish National Center for Cardiovascular Research) and at the Hospital de la Princesa in Madrid, as well as at the Principe Felipe Research Center in Valencia.
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Honores y reconocimientos
Merck-Serono Award, Salud 2000 Foundation. Clinical investigation Area | 2015 |
Merck Serono Award, Salud 200 Foundation. Clinical investigation Area | 2004 |
ICIRA Award, to the best IVF innovation Project | 2009 |
Spanish Fertility Society Award | 2000 |
Associate Editor Human Reproduction | 2013 |
Publicaciones
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Novel nonclassic progesterone receptor PGRMC1 pulldown-precipitated proteins reveal a key role during human decidualization.
Salsano S González-Martín R Quiñonero A López-Martín S Gómez-Escribano AP Pérez-Debén S Yañez-Mo M Domínguez F
Fertil Steril. 2020 May;113(5):1050-1066.e7. doi: 10.1016/j.fertnstert.2020.01.008 -
Preeclampsia: a defect in decidualization is associated with deficiency of Annexin A2.
Garrido-Gomez T Quiñonero A Dominguez F Rubert L Perales A Hajjar KA Simon C
Am J Obstet Gynecol. 2019 Nov 15. pii: S0002-9378(19)32624-9. doi: 10.1016/j.ajog.2019.11.1250. [Epub ahead of print] -
Phytoestrogen exposure alters endometrial stromal cells and interferes with decidualization signaling.
Salsano S Pérez-Debén S Quiñonero A González-Martín R Domínguez F
Fertil Steril. 2019 Jul 29. pii: S0015-0282(19)30547-3. doi: 10.1016/j.fertnstert.2019.06.014. [Epub ahead of print] -
Inhibition of KIF20A by BKS0349 reduces endometriotic lesions in a xenograft mouse model.
Ferrero H Corachán A Quiñonero A Bougeret C Pouletty P Pellicer A Domínguez F
Mol Hum Reprod. 2019 Jul 31. pii: gaz044. doi: 10.1093/molehr/gaz044. [Epub ahead of print] -
Transcriptomic behavior of genes associated with chromosome 21 aneuploidies in early embryo development.
Sanchez-Ribas I Diaz-Gimeno P Sebastián-León P Mercader A Quiñonero A Ballesteros A Pellicer A Domínguez F
Fertil Steril. 2019 May;111(5):991-1001.e2. doi: 10.1016/j.fertnstert.2019.01.023. Epub 2019 Mar 25 -
An artificial intelligence model based on the proteomic profile of euploid embryos and time-lapse images: a preliminary study
Bori L Dominguez F Fernandez E I DelGallego R Alegra L Hickmane C Quiñonero A Nogueirad M F G Rochard J C Meseguera M
Reproductive BioMedicine OnlineIn press, journal pre-proofAvailable online 8 October 2020 -
TRAQ comparison of proteomic profiles of endometrial receptivity.
Pérez-Debén S Bellver J Alamá P Salsano S Quiñonero A Sebastian-Leon P Díaz-Gimeno P Domínguez F
J Proteomics. 2019 May 15:103381. doi: 10.1016/j.jprot.2019.103381. [Epub ahead of print] -
Single-cell RNA sequencing of oocytes from ovarian endometriosis patients reveals a differential transcriptomic profile associated with lower quality.
Ferrero H Corachán A Aguilar A Quiñonero A Carbajo-García MC Alamá P Tejera A Taboas E Muñoz E Pellicer A Domínguez F
Hum Reprod. 2019 Jun 18. pii: dez053. doi: 10.1093/humrep/dez053. [Epub ahead of print] -
Deregulation of miR-324/Kiss1/kisspeptin in early ectopic pregnancy: Mechanistic findings with clinical and diagnostic implications.
Romero-Ruiz A Avendaño MS Dominguez F Lozoya T Molina-Abril H Sangiao-Alvarellos S Gurrea M Lara-Chica M Fernandez-Sanchez M Torres E Perdices-Lopez C Abbara A Steffani L Calzado MA Dhillo WS Pellicer A Tena-Sempere M
Am J Obstet Gynecol. 2019 Jan 29. pii: S0002-9378(19)30282-0. doi: 10.1016/j.ajog.2019.01.228. [Epub ahead of print -
Cytokines in embryonic secretome as potential markers for embryo selection.
Bahrami-Asl Z Hajipour H Rastgar Rezaei Y Novinbahador T Latifi Z Nejabati HR Farzadi L Fattahi A Nouri M Dominguez F
Am J Reprod Immunol. 2020 Dec 9:e13385. doi: 10.1111/aji.13385. Online ahead of print.
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Presentations
- Palomar A Gonzalez-Martin R Salsano S Pérez-Debén S Quiñonero A Domínguez F O-105 Entosis Occurs in Human Embryo Implantation.. Presented at the 67th Annual Meeting of the Society for Reproductive Investigation, Vancouver ,Canada, March 10-14, 2020
- Gonzalez-Martin R Palomar A Pérez-Debén S Quiñonero A Dominguez F F-209 Mercury Disturbs Reproductive Functions of Primary Endometrial Stromal Cells (ESC).. Presented at the 67th Annual Meeting of the Society for Reproductive Investigation, Vancouver ,Canada, March 10-14, 2020
- Pellicer N Buigues A Dominguez F Susana Martinez-cuenca Pellicer A Herraiz S P-787 Autologous stem cell ovarian transplantation (ASCOT) revitalized the aged blood-borne secretome in Poor responder (PR) women. Presented at the 35th annual meeting of the European Society of Human Reproduction and Embryology, Vienna, Austria, 14-16 October 2019
- Marin L Campos-Galindo I Dominguez F De los Santos MJ Mercader A Simon C Rubio C P-574 Effect of genistein and daidzein levels on ovarian response and embryo quality in PGT-A cycles. Presented at the 35th annual meeting of the European Society of Human Reproduction and Embryology, Paris, France, 14-16 October 2019
- Meseguer M Bori L Del Gallego R Remohí J Quinonero A Dominguez F P-134: Protein profile of euploid single embryo transfer reveals differential patterns among them.. Presented at the 74th Scientific Congress & Expo of the American Society for Reproductive Medicine, Denver, CO, USA, 23-26 June 2019
- Ferrero H Corachán A Quiñonero A Bougeret C Pellicer A Dominguez F . P-315: Inhibition of KIF20A reduces endometriosis implants in a randomized xenograft mouse model. Presented at the 74th Scientific Congress & Expo of the American Society for Reproductive Medicine, Denver, CO, USA, 23-26 June 2019
- Ferrero H Corachán A Quiñonero A Carbajo-García C Alamá P Tejera A Taboas E Muñoz E Pellicer A Domínguez F NGS of Oocytes from Endometriosis Patients Reveals a Differential Transcriptomic Pattern. Presented at the 34rd annual meeting of the European Society of Human Reproduction and Embryology, Barcelona, Spain, March 12-16, 2019
- Gonzalez-Martin R Quiñonero A Pérez S Salsano S Domínguez F Acute DEHP Exposure in Endometrial Epithelial Cells Does Not Phenocopy the Alterations Described in Endometriosis.. Presented at the 34rd annual meeting of the European Society of Human Reproduction and Embryology, Barcelona, Spain, March 12-16, 2019
- Gonzalez-Martin R Telez-Plaza M Domínguez F Association of Blood Cadmium and Lead Levels with Reproductive Lifespan Among Postmenopausal Women: NHANES 2005-2014. . Presented at the 34rd annual meeting of the European Society of Human Reproduction and Embryology, Barcelona, Spain, March 12-16, 2019
- Gonzalez-Martin R Quiñonero A Pérez-Debent S Salsano S Domínguez F Endometrial Stromal Cells Acutely Exposed to DEHP Do Not Recapitulate Alterations Observed in Endometriosis_. Presented at the 34rd annual meeting of the European Society of Human Reproduction and Embryology, Barcelona, Spain, March 12-16, 2019
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