Hortensia Ferrero, Ph.D.
Treatment and Diagnosis of Uterine Diseases Research Group Leader
FIVI Valencia
Hortensia Ferrero, Ph.D.
Biografía
Dr. Hortensia Ferrero is a full-time investigator at FIVI-INCLIVA through a Sara Borrell Grant by Health Institute Carlos III and research group leader for treatment and diagnosis of uterine diseases at IVI Foundation in Valencia. She obtained her Bachelors degree form the University of Valencia in 2006, with a major in Biology. She then obtained a Master’s Degree in Biotechnology and Biomedicine (2008), focusing on Human Reproductive Biology. She carried out her PhD studies with a PFIS fellowship granted by Health Institute Carlos III. In 2013, she worked six months with Dr. D. Stephen Charnock-Jones’ group at University of Cambridge in the Department of Obstetrics and Gynaecology, in the UK, supported by a grant by Health Institute Carlos III. She received her PhD degree in Biotechnology with special international mention, in 2014 from University of Valencia. Her thesis project on the angiogenic process regulating the corpus luteum in physiological and pathological conditions recieved an Extraordinary Award in 2015.
Read more
Publicaciones
-
A Natural Xenogeneic Endometrial Extracellular Matrix Hydrogel Toward Improving Current Human in vitro Models and Future in vivo Applications.
López-Martínez S Campo H de Miguel-Gómez L Faus A Navarro AT Díaz A Pellicer A Ferrero H Cervelló I
Front Bioeng Biotechnol. 2021 Mar 5;9:639688. doi: 10.3389/fbioe.2021.639688. eCollection 2021. -
Vitamin D as an effective treatment in human uterine leiomyomas independent of mediator complex subunit 12 mutation.
Corachán A Trejo MG Carbajo-García MC Monleón J Escrig J Faus A Pellicer A Cervelló I Ferrero H
Fertil Steril. 2020 Oct 7:S0015-0282(20)30710-X. doi: 10.1016/j.fertnstert.2020.07.049. Online ahead of print. -
Commentary on regulation of leiomyoma stem cell proliferation by WNT4 via AKT-dependent ?-Catenin activation.
Ferrero H
Fertil Steril. 2020 Dec;114(6):1192-1193. doi: 10.1016/j.fertnstert.2020.09.148. -
HMGA2 involvement in uterine leiomyomas development through angiogenesis activation.
Ferrero H
Fertil Steril. 2020 Sep 14:S0015-0282(20)30697-X. doi: 10.1016/j.fertnstert.2020.07.044. Online ahead of print. -
Stem cell paracrine actions in tissue regeneration and potential therapeutic effect in human endometrium: a retrospective study
Miguel-Gómez L Ferrero H López-Martínez S Campo H López-Pérez Faus A Hervás D Santamaría X Pellicer A Cervelló I
BJOG. 2020 Apr;127(5):551-560. doi: 10.1111/1471-0528.16078. Epub 2020 Jan 19. -
Stem cell paracrine actions in tissue regeneration and potential therapeutic effect in human endometrium: a retrospective study.
Miguel-Gómez L Ferrero H López-Martínez S Campo H López-Pérez N Faus A Hervás D Santamaría X Pellicer A Cervelló I
BJOG. 2020 Apr;127(5):551-560. doi: 10.1111/1471-0528.16078. Epub 2020 Jan 19. -
Long-term vitamin D treatment decreases human uterine leiomyoma size in a xenograft animal model.
Corachán A Ferrero H Escrig J Monleon J Faus A Cervelló I Pellicer A
Fertil Steril. 2019 Nov 15. pii: S0015-0282(19)32372-6. doi: 10.1016/j.fertnstert.2019.09.018. [Epub ahead of print] -
Inhibition of KIF20A by BKS0349 reduces endometriotic lesions in a xenograft mouse model.
Ferrero H Corachán A Quiñonero A Bougeret C Pouletty P Pellicer A Domínguez F
Mol Hum Reprod. 2019 Jul 31. pii: gaz044. doi: 10.1093/molehr/gaz044. [Epub ahead of print] -
Single-cell RNA sequencing of oocytes from ovarian endometriosis patients reveals a differential transcriptomic profile associated with lower quality.
Ferrero H Corachán A Aguilar A Quiñonero A Carbajo-García MC Alamá P Tejera A Taboas E Muñoz E Pellicer A Domínguez F
Hum Reprod. 2019 Jun 18. pii: dez053. doi: 10.1093/humrep/dez053. [Epub ahead of print] -
Inhibition of tumor cell proliferation in human uterine leiomyomas by vitamin D via Wnt/?-catenin pathway.
Corachán A Ferrero H Aguilar A García N Monleon J Faus A Cervelló I Pellicer A
Fertil Steril, NA:NA -NA, 2018.
Read more
Presentations
- Corachán A Trejo MG Carbajo-García MC Faus A Escrig J Monleón J Pellicer A Cervelló I Ferrero H Vitamin D as an effective treatment to reduce cell proliferation and extra cellular matrix formation in human uterine leiomyomas regardless MED12 mutation status.. Presented at the 36th annual meeting of the European Society of Human Reproduction and Embryology, Copenhagen,Denmark, July 5-8, 2020
- Corachán A Ferrero H Escrig J Monleón J Faus A Cervelló I Pellicer A O-208 VITAMIN D LONG-TERM TREATMENT DECREASES HUMAN UTERINE LEIOMYOMA SIZE THROUGH SPECIFIC MOLECULAR MECHANISMS IN A XENOGRAFT ANIMAL MODEL. Presented at the 35th annual meeting of the European Society of Human Reproduction and Embryology, Vienna, Austria, 14-16 October 2019
- López Martínez S Campo H De Miguel-Gómez L Faus A Ferrero H Cervelló I O-121: Improving three-dimensional in vitro culture methods of human endometrial stem cells: bioengineering tissue-specific hydrogels. Presented at the 74th Scientific Congress & Expo of the American Society for Reproductive Medicine, Denver, CO, USA, 23-26 June 2019
- De Miguel Gómez L López Martínez S Faus A Hervás D Ferrero H Cervelló I P-790: Stem cell therapy induces a shift from an inflammatory environment towards an immune tolerant scenario promoting endometrial tissue regeneration. Presented at the 74th Scientific Congress & Expo of the American Society for Reproductive Medicine, Denver, CO, USA, 23-26 June 2019
- Ferrero H Corachán A Quiñonero A Bougeret C Pellicer A Dominguez F . P-315: Inhibition of KIF20A reduces endometriosis implants in a randomized xenograft mouse model. Presented at the 74th Scientific Congress & Expo of the American Society for Reproductive Medicine, Denver, CO, USA, 23-26 June 2019
- Corachán A Ferrero H Escrig J Monleón J Faus A Cervelló I Pellicer A Eects of Vitamin D in Human Uterine Leiomyoma Growth in a Xenograft Animal Model.. Presented at the 34rd annual meeting of the European Society of Human Reproduction and Embryology, Barcelona, Spain, March 12-16, 2019
- Ferrero H Corachán A Quiñonero A Carbajo-García C Alamá P Tejera A Taboas E Muñoz E Pellicer A Domínguez F NGS of Oocytes from Endometriosis Patients Reveals a Differential Transcriptomic Pattern. Presented at the 34rd annual meeting of the European Society of Human Reproduction and Embryology, Barcelona, Spain, March 12-16, 2019
- Corachán A Ferrero H Aguilar A García N Monleón J Faus A Galiano D Cervelló I Pellicer A Vitamin D can inhibit proliferation of uterine fibroid cells in vitro through the Wnt/?-Catenin signalling pathway. , , July 2-5 ,2017
- García N Aguilar A Corachán A Monleón J Ferrero H Galiano D Navarro AT Cervelló I Pellicer A In vitro proliferation of uterine fibroids is related with vitamin D receptor and patient´s age. , , July 2-5 ,2017
Read more