
Irene Cervelló, Ph.D.
FIVI Valencia
Biografía
Dr. Irene Cervelló is a full-time investigator at FIVI-INCLIVA and Laboratory Manager & Endometrial Stem Cell and Bioengineering Research Group Leader at the IVI Foundation Research Department. She obtained her Bachelor’s degree in Biology in 2000, and her doctorate degree as “cum laude” with extraordinary prize in 2008, in the Pediatrics, Obstetrics and Gynaecology Department at the University of Valencia School of Medicine. During her post-doctoral training, she was a visiting scholar for five months at the Wake Forest Institute for Regenerative Medicine in North Carolina), USA, where she also performed tasks related to the revision of scientific articles and R&D project evaluations (Well Being of Women – ENGLAND and National Science Center-POLONIA).
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Honores y reconocimientos
University of Valencia School of Medicine, Spain, Scholarship for pre-doctoral training | (2003-2005) |
IVI Foundation (Spain) Scholarship for pre-doctoral training | (2005-2006) |
Ministry of Education (Spain)-Equipo IVI pre-doctoral contract | (2007-2008) |
Extraordinary PhD Thesis Award, University of Valencia (Spain) | (2008) |
President’s Presenter Award, Society for Reproductive Investigation (formerly Society for Gynecologic Investigation) (SRI) | (2009) |
Basic Science Award, European Society of Human Reproduction and Embryology (ESHRE) | (2012) |
“José Castillejo” program grant for young researchers (Ministry of Education (Spain)) for postdoctoral training at the Wake Forest Institute for Regenerative Medicine | (2013) |
Publicaciones
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Microphysiological Modeling of the Human Endometrium.
Campo H Murphy A Yildiz S Woodruff T Cervelló I Kim JJ
Tissue Eng Part A. 2020 Apr 28. doi: 10.1089/ten.tea.2020.0022. Online ahead of print. -
Stem cell paracrine actions in tissue regeneration and potential therapeutic effect in human endometrium: a retrospective study
Miguel-Gómez L Ferrero H López-Martínez S Campo H López-Pérez Faus A Hervás D Santamaría X Pellicer A Cervelló I
BJOG. 2020 Apr;127(5):551-560. doi: 10.1111/1471-0528.16078. Epub 2020 Jan 19. -
Stem cell paracrine actions in tissue regeneration and potential therapeutic effect in human endometrium: a retrospective study.
Miguel-Gómez L Ferrero H López-Martínez S Campo H López-Pérez N Faus A Hervás D Santamaría X Pellicer A Cervelló I
BJOG. 2020 Apr;127(5):551-560. doi: 10.1111/1471-0528.16078. Epub 2020 Jan 19. -
Bioengineering strategies of the uterus towards improving current investigative models and female reproductive health.
Campo H Cervelló I pellicer A
Facts Views Vis Obgyn. 2019 Mar;11(1):87-99. -
Long-term vitamin D treatment decreases human uterine leiomyoma size in a xenograft animal model.
Corachán A Ferrero H Escrig J Monleon J Faus A Cervelló I Pellicer A
Fertil Steril. 2019 Nov 15. pii: S0015-0282(19)32372-6. doi: 10.1016/j.fertnstert.2019.09.018. [Epub ahead of print] -
Vitamin D as an effective treatment in human uterine leiomyomas independent of mediator complex subunit 12 mutation.
Corachán A Trejo MG Carbajo-García MC Monleón J Escrig J Faus A Pellicer A Cervelló I Ferrero H
Fertil Steril. 2020 Oct 7:S0015-0282(20)30710-X. doi: 10.1016/j.fertnstert.2020.07.049. Online ahead of print. -
Tissue-specific decellularized endometrial substratum mimicking different physiological conditions influences in vitro embryo development in a rabbit model.
Campo H García-Domínguez X López-Martínez S Faus A Salvador Vicente Antón J Marco-Jiménez F Cervelló I
Acta Biomater. 2019 Mar 5. pii: S1742-7061(19)30170-9. doi: 10.1016/j.actbio.2019.03.004. [Epub ahead of print] -
Reply: Bone marrow-derived endometrial cells: what you see is what you get.
Santamaria X Mas A Cervelló I Taylor HS Simon C
Hum Reprod Update. 2018 Dec 21. doi: 10.1093/humupd/dmy042. [Epub ahead of print] No abstract available. -
Personalized medicine through three-dimensional cell-based culture systems in assisted reproductive technologies: how close are we?
Diaz-Gimeno P Cervelló I
Fertil Steril. 2020 Aug 21:S0015-0282(20)30674-9. doi: 10.1016/j.fertnstert.2020.07.021. Online ahead of print. -
Comparison of different sources of platelet-rich plasma as treatment option for infertility-causing endometrial pathologies
Miguel–Gómez L López-Martínez S Campo H Francés-Herrero E Amparo Faus Ana Díaz Pellicer A Domínguez F Cervelló I
Fertility and SterilityIn press, corrected proofAvailable online 24 August 2020
- Bioengineering the Uterus: An Overview of Recent Advances and Future Perspectives in Reproductive Medicine.
Campo H, Cervelló I, Simón C.
Ann Biomed Eng, 45(7):1710-1717, 2017. - Autologous cell therapy with CD133+ bone marrow-derived stem cells for refractory Asherman's syndrome and endometrial atrophy: a pilot cohort study.
Santamaria X, Cabanillas S, Cervelló I, Arbona C, Raga F, Ferro J, Palmero J, Remohí J, Pellicer A, Simón C.
Hum Reprod, 31(5):1087-96, 2016. - Translating Regenerative Medicine to the Clinic. Advances in Translational Medicine. Regenerative Medicine and Tissue Engineering in Reproductive Medicine: Future Clinical Applications in Human Infertility.
Cervelló I, Medrano JV, Simón C.
Elsevier Inc. 2016. - Human CD133(+) bone marrow-derived stem cells promote endometrial proliferation in a murine model of Asherman syndrome.
Cervelló I, Gil-Sanchis C, Santamaría X, Cabanillas S, Díaz A, Faus A, Pellicer A, Simón C.
Fertil Steril, 104(6):1552-60, 2015. - Contribution of different bone marrow-derived cell types in endometrial regeneration using an irradiated murine model.
Gil-Sanchis C, Cervelló I, Khurana S, Faus A, Verfaillie C, Simón C.
Fertil Steril, 103(6):1596-605, 2015. - Overexpression of the truncated form of High Mobility Group A proteins (HMGA2) in human myometrial cells induces leiomyoma-like tissue formation.
Mas A, Cervelló I, Fernández-Álvarez A, Faus A, Díaz A, Burgués O, Casado M, Simón C.
Mol Hum Reprod, 21(4):330-8, 2015.
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Presentations
- Corachán A Trejo MG Carbajo-García MC Faus A Escrig J Monleón J Pellicer A Cervelló I Ferrero H Vitamin D as an effective treatment to reduce cell proliferation and extra cellular matrix formation in human uterine leiomyomas regardless MED12 mutation status.. Presented at the 36th annual meeting of the European Society of Human Reproduction and Embryology, Copenhagen,Denmark, July 5-8, 2020
- Corachán A Ferrero H Escrig J Monleón J Faus A Cervelló I Pellicer A O-208 VITAMIN D LONG-TERM TREATMENT DECREASES HUMAN UTERINE LEIOMYOMA SIZE THROUGH SPECIFIC MOLECULAR MECHANISMS IN A XENOGRAFT ANIMAL MODEL. Presented at the 35th annual meeting of the European Society of Human Reproduction and Embryology, Vienna, Austria, 14-16 October 2019
- López Martínez S Campo H De Miguel-Gómez L Faus A Ferrero H Cervelló I O-121: Improving three-dimensional in vitro culture methods of human endometrial stem cells: bioengineering tissue-specific hydrogels. Presented at the 74th Scientific Congress & Expo of the American Society for Reproductive Medicine, Denver, CO, USA, 23-26 June 2019
- De Miguel Gómez L López Martínez S Faus A Hervás D Ferrero H Cervelló I P-790: Stem cell therapy induces a shift from an inflammatory environment towards an immune tolerant scenario promoting endometrial tissue regeneration. Presented at the 74th Scientific Congress & Expo of the American Society for Reproductive Medicine, Denver, CO, USA, 23-26 June 2019
- Campo H García-Domínguez X López-Martínez S Antón J Marco-jiménez F Cervelló I Biomimetic Coatings from Decellularized Rabbit Endometrium Inuence the In Vitro In Vitro Development of PreImplantation Embryos. . Presented at the 34rd annual meeting of the European Society of Human Reproduction and Embryology, Barcelona, Spain, March 12-16, 2019
- Corachán A Ferrero H Escrig J Monleón J Faus A Cervelló I Pellicer A Eects of Vitamin D in Human Uterine Leiomyoma Growth in a Xenograft Animal Model.. Presented at the 34rd annual meeting of the European Society of Human Reproduction and Embryology, Barcelona, Spain, March 12-16, 2019
- De Miguel-Gómez L Faus A López-Martínez S López-Pérez N Castillón G Pellicer A Cervelló I Human Platelet-Rich Plasma from Patients with Uterine Pathologies Contributes to Endometrial Regeneration: A Current Therapeutic Approach? . Presented at the 34rd annual meeting of the European Society of Human Reproduction and Embryology, Barcelona, Spain, March 12-16, 2019
- López-Pérez N Santamaría X Díaz-Gimeno P Sebastian-Leon P Faus A Remohí J Pellicer A Simón C Cervelló I Stem Cell-Secreted Paracrine Factors in Human Endometrial Regeneration . Presented at the 33rd annual meeting of the European Society of Human Reproduction and Embryology, Geneva,Switerland, March 6-10,2018
- Corachán A Ferrero H Aguilar A García N Monleón J Faus A Galiano D Cervelló I Pellicer A Vitamin D can inhibit proliferation of uterine fibroid cells in vitro through the Wnt/?-Catenin signalling pathway. , , July 2-5 ,2017
- García N Aguilar A Corachán A Monleón J Ferrero H Galiano D Navarro AT Cervelló I Pellicer A In vitro proliferation of uterine fibroids is related with vitamin D receptor and patient´s age. , , July 2-5 ,2017
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