The consequences of reproductive aging are encountered on a daily basis in the infertility clinic. With this in mind, researchers at IVI RMA Global are working to identify the mechanisms responsible for reproductive aging.
These projects include studies on:
- changes in the epigenome associated with aging,
- telomere dynamics in gametes and peripheral blood
- mitochondrial function in preimplantation embryos.
The scientific team is also focused on devising treatment strategies to activate dormant follicles in patients at advanced stages of reproductive aging. These techniques have produced pregnancies in multiple patients with a diagnosis of primary ovarian insufficiency (also termed premature ovarian failure).