Surgery

Reproductive endocrinologists have traditionally been pioneers of minimally invasive reproductive and gynecologic surgery, with the ultimate goal of restoring normal anatomy in the gentlest manner possible in order to maximize chance of healthy pregnancy.

Research and development in this field has had a drastic impact on the physical and emotional burden of infertility patients and contributed to an improvement on overall quality of life. The application of hysteroscopic, laparoscopic and robotic surgery techniques have led to faster recoveries, less surgical risk and complications and improved reproductive outcomes.

As minimally invasive techniques become the mainstay of surgical approach, technological advancements are being explored to increase ease, accessibility and cost-effectiveness. In addition, who, what and when to operate remain the cornerstones of surgical investigation.

Investigators working in this area

Linnea Goodman, M.D.

Obstetrician and Gynecologist at RMA of New Jersey

RMA New Jersey

Elena Labarta, M.D., Ph.D.

Specialist in Human Reproduction and Assisted Reproductive Techniques at IVI Valencia

IVI Valencia

James Hotaling, M.D.

Urologist Specialist in Male Infertility and Men’s Health at RMA of new Jersey

RMA New Jersey

Human Fatemi, M.D., Ph.D.

Medical Director of the IVI Middle East

IVI Middle East

Carmina Vidal, M.D., Ph.D.

Gynecologist and Reproductive Medicine Specialist at IVI Valencia

IVI Valencia

María Cerrillo, M.D., Ph.D.

Reproductive Endocrinology and Infertility Specialist at IVI Madrid

IVI Madrid

Juan Giles, M.D.

Gynecologist at IVI Valencia and Clinical Researcher at the INCLIVA Institute

IVI Valencia

Fabio Cruz, M.D.

Gynecologist and Reproductive Medicine Specialist at IVI Valencia

IVI Valencia

Laura Melado Vidales, M.D., Ph.D.

IVF specialist IVI Middle East

IVI Middle East

Roberto Matorras, M.D., Ph.D.

Coordinator for Research and Education at IVI Bilbao

IVI Bilbao

Clinical outcomes after the transfer of blastocysts characterized as mosaic by high resolution Next Generation Sequencing- further insights.
Munné S Spinella F Grifo J Zhang J Beltran MP Fragouli E Fiorentino F
Eur J Med Genet. 2019 Aug 21:103741. doi: 10.1016/j.ejmg.2019.103741. [Epub ahead of print]
The vaginal microbiome in uterine transplantation.
Jones BP Soso S L'Heveder A Bracewell-Milnes T Thum MY Diaz-Garcia C Maclntyre DA Quiroga I Ghaem-Maghami S Testa G Johannesson L Bennett PR Yazbek J Smith JR
BJOG. 2019 Aug 8. doi: 10.1111/1471-0528.15881. [Epub ahead of print] Review.
Human uterine transplantation: a review of outcomes from the first 45 cases.
Jones BP Soso S Bracewell-Milnes T Thum MY Nicopoullos J Diaz-Garcia C Friend P Ghaem-Maghami S Johannesson L Quiroga l Yazbek J Smith JR
BJOG. 2019 Aug 13. doi: 10.1111/1471-0528.15863. [Epub ahead of print] Review.
Congenital Uterine Malformation by Experts (CUME): T-shaped uterus.
Ludwin A Coelho Neto MA Ludwin I Nastri CO Acién M Alcazar JL Benacerraf B Condous G DeCherney A De Wilde RL Diamond MP Emanuel MH Guerriero S Hurd W Levine D Lindheim S Pellicer A Petraglia F Saridogan E Matins WP
Ultrasound Obstet Gynecol. 2019 Aug 20. doi: 10.1002/uog.20845. [Epub ahead of print]
Rethinking the time interval to embryo transfer after uterus transplantation - DUETS (Dallas UtErus Transplant Study).
Johannesson L Wall A Putman JM Zhang L Testa G Diaz-Garcia C
BJOG. 2019 Jul 8. doi: 10.1111/1471-0528.15860. [Epub ahead of print]
Dexamethasone does not prevent malignant cell reintroduction in leukemia patients undergoing ovarian transplant: risk assessment of leukemic cell transmission by a xenograft model.
Diaz-Garcia C Herraiz S Such E Andrés MM Villamón E Mayordomo-Aranda E Cervera J Sanz MA Pellicer A
Hum Reprod. 2019 Jul 24. pii: dez115. doi: 10.1093/humrep/dez115. [Epub ahead of print]
Reproductive outcomes after hysteroscopic metroplasy for women with dysmorphic uterus and recurrent implantation failure
Ferro J Labarta E Saenz C Montoya P Remohí J
Facts Views Vis Obgyn 2019, 63-68
Reproductive outcomes after hysteroscopic metroplasy for women with ...
Ferro J Labarta E Saenz C Montoya P Remohí J
Facts Views Vis Obgyn 2019, 63-68
Uterus transplantation from a deceased donor.
Diaz-Garcia C Pellicer A
Lancet. 2018 Dec 4. pii: S0140-6736(18)32106-8. doi: 10.1016/S0140-6736(18)32106-8. [Epub ahead of print] No abstract available.
Uterus Transplantation: A Rapidly Expanding Field.
Brännström M Dahm Kähler Greite R Mölne J Diaz-Garcia C Tullius SG
Transplantation, 102(4):569-577, 2018.

Hysteroscopic septum resection and reproductive medicine: A SWOT analysis.
Spanish Infertility SWOT Group (SISG) Checa MA Bellver J Bosch E Espinós JJ Fabregues F Fontes J García-Velasco JA Requena A
Reprod Biomed Online, 37(6):709-715, 2018.
Congenital Uterine Malformation by Experts (CUME): better criteria for distinguishing between normal/arcuate and septate uterus?
Ludwin A Martins WP Nastri CO Ludwin I Coelho Neto MA Leitão VM Acién M Alcazar JL Benacerraf B Condous G De Wilde RL Emanuel MH Gibbons W Guerriero S Hurd WW Levine D Lindheim S Pellicer A Petraglia F Saridogan E
Ultrasound Obstet Gynecol, 51(1):101-109, 2018.
3D NIR-II Molecular Imaging Distinguishes Targeted Organs with High-Performance NIR-II Bioconjugates.
Zhu S Herraiz S Yue J Zhang M Wan H Yang Q Ma Z Wang Y He J Antaris AL Zhong Y Diao S Feng Y Zhou Y Yu K Hong G Liang Y Hsueh AJ Dai H
Adv Mater, 30(13):NA-NA, 2018.
A call for standardized outcomes in microTESE.
Jensen CF Dupree JM Sonksen J Ohl D Hotaling J
Andrology, 5(3), 403, 2017
Urethral Strictures and Artificial Urinary Sphincter Placement. [Review]
Myers JB Brant WO Hotaling J Lenherr SM
Urol Clin North Am, 44(1), 93-103, 2017.
Versatility of the suprapubic port in robotic assisted laparoscopic myomectomy.
Gueye NA Goodman L Falcone T
Fertil Steril. 2017 Sep;108(3).
The Use of Laparoscopy Simulation to Explore Gender Differences in Resident Surgical Confidence.
Flyckt RL White EE Goodman L Mohr C Dutta S Zanotti KM
Obstet Gynecol Int. 2017;2017:1945801.
Ovarian transposition: a surgical option for fertility preservation.
Arian SE Goodman L Flyckt RL Falcone T
BJOG. 2017 Apr 22.
Laparoscopic Vaginal-Assisted Hysterectomy with Complete Vaginectomy for Female-To-Male Genital Reassignment Surgery.
Gomes da Costa A Valentim-Lourenço A Valentim-Lourenço A Santos-Ribeiro S Carvalho Afonso M Henriques A Ribeirinho AL Décio Ferreira J
J Minim Invasive Gynecol 2016;23(3):404-9
Adenomyosis in infertile women: prevalence and the role of 3D ultrasound as a marker of severity of the disease.
Puente J Fabris A Patel J Patel A Cerrillo M Requena A García-Velasco JA
Reprod Biol Endocrinol 2016; 14: 60
Effect of surgery on ovarian reserve in women with endometriomas, endometriosis and controls.
Goodman L Goldberg J Flyckt RL Gupta M Harwalkar J Falcone T
Am J Obstet Gynecol. 2016 Nov;215(5):589.e1-589.e6.
Hysteroscopy before IVF: can it improve outcomes?
Pellicer A Galliano D
Lancet; 387 (10038): 2578-2579, 2016.
Optimal uterine anatomy and physiology necessary for normal implantation and placentation.
De Ziegler D Pirtea P Galliano D Cicinelli E Meldrum D
Fertil Steril; 105 (4): 844-854, 2016
Assisted reproductive techniques after fertility-sparing treatments in gynaecological cancers
Zapardiel I Cruz M Diestro MD Requena A García-Velasco JA
Hum Reprod Update, 22, 2016.
Adenomyosis in infertile women: prevalence and the role of 3D ultrasound as a marker of severity of the disease
Puente J Fabris A Patel J Patel A Cerrillo M Requena A García-Velasco JA
Reprod Biol Endocrinol, 14(1):60, 2016
Surgical Management of Ureteral Strictures Arising From Radiotherapy for Prostate Cancer.
Orchard J Tward JD Lenherr S Hotaling J Brant WO Myers JB
Urol Case Rep, 6, 47-9, 2016.
Cardiovascular Autonomic Neuropathy, Sexual Dysfunction, and Urinary Incontinence in Women With Type 1 Diabetes.
Hotaling J Sarma AV Patel DP Braffett BH Cleary PA Feldman E Herman WH Martin CL Jacobson AM Wessells H Pop-Busui R
Diabetes Care, 39(9), 1587-93, 2016.
Genetic mutation that may contribute to failure of prolapse surgery in Caucasian women: A case-control study.
St Louis S Scott RT Lewis C Salamon C Pagnillo J Treff N Taylor D Culligan P
J Minim Invasive Gynecol, 23:726-30, 2016.
Trends Over Time and Surgical Outcomes of Abdominal, Mini-Laparotomy, and Traditional and Robotic-Assisted Laparoscopy With and Without Tandem Mini-Laparotomy: A Comparison of Myomectomy Techniques
Stanhiser J Mouille B Flyckt R Goldberg J Falcone T Goodman L
J Minim Invasive Gynecol. 2015 Nov-Dec;22(6S):S1.
Supraumbilical primary trocar insertion for laparoscopic access: the relationship between points of entry and retroperitoneal vital vasculature by imaging.
Stanhiser J Goodman L Soto E Al-Aref I Wu J Gojayev A Nutter B Falcone T
Am J Obstet Gynecol. 2015 Oct;213(4):506.e1-5
Introducing Larger Equipment: A Novel Method in Laparoscopic Surgery with Smaller Port Sites.
Kim S Goodman L Goldberg J
J Minim Invasive Gynecol. 2015 Nov-Dec;22(6S):S136
Ergonomic Strain in Minimally Invasive Surgery: Addressing the Strain Epidemic.
Franasiak JM Gehrig P
J Clin Outcomes Management, Vol 22 (6), 2015.
Inherent difficulties of meta-analysis for surgical techniques in male infertility: an argument for standardizing reporting and outcomes.
Anderson R Hotaling J
Fertil Steril, 104(5), 1127-8, 2015.
Robotic single-site myomectomy: a step-by-step tutorial.
Gargiulo A Lewis E Kaser DJ Srouji SS
Fertil Steril, 104(5):e13. 2015.
Techniques for enclosed morcellation in gynecologic surgery.
Srouji S Kaser DJ Gargiulo AR
Fertil Steril103:e34. 2015.
Factors affecting the outcome of “Endometrial Scratch” in women with recurrent implantation failure.
Coughlan C Yuan X Demirol A Ledger W Li T
J Reprod Med, 59 (1-2): 39 – 43, 2014
Pregnancy success after hysteroscopic sterilization reversal.
Franasiak JM Monteith C Berger G Zerden M
Obstetrics and Gynecology 124(6):1183-9, 2014. recognized for editorial assistance.
Simple circumcision device: proof of concept for a single-visit, adjustable device to facilitate safe adult male circumcision.
Kadlec AO Ohlander S Hotaling J Hannick J Niederberger C Turk TM
Urolithiasis, 42(4), 323-7, 2014.
Demographics of pediatric renal trauma.
Grimsby GM Voelzke B Hotaling J Sorensen MD Koyle M Jacobs MA
J Urol, 192(5), 1498-502, 2014.
Management of adults with prior failed hypospadias surgery. [Review].
Craig JR Wallis C Brant WO Hotaling J Myers JB
Transl Androl Urol, 3(2), 196-204, 2014.
Is there still a role for primary realignment for stricture due to pelvic fracture?
Brant WO Hotaling J
J Urol, 192(6), 1595-6, 2014.
Outcomes of splenectomy in patients with Common Variable Immunodeficiency (CVID): a survey of 45 patients
Wong G Goldacker S Winterhalter C Grimbacher B Chapel HM Lucas M Alecsandru D McEwen D Quinti I Martini H Milito C Schmidt R Ernst D Espanol T Vidaller A
Clin Exp Immunol, 172(1):63-72, 2013.
Undifferentiated round cell sarcoma of the broad ligament.
Diaz-Murillo R Iglesias C Zapardiel I
Ecancermecialscience, 9;7:303, 2013.
Ergonomic deficits in robotic gynecologic oncology surgery: A need for intervention.
Craven R Franasiak JM Mosaly P Gehrig PA
J Minimal Inv Gynecol 20:648-55, 2013. †Authors contributed equally.
Publication misrepresentation among urology residency applicants.
SHsi RS Hotaling J Moore TN Joyner BD
World J Urol, 31(3), 697-702, 2013.
Contemporary trends in the immediate surgical management of renal trauma using a national database.
McClung C Hotaling J Wang J Wessells H Voelzke B
J Trauma Acute Care Surg, 75(4), 602-606, 2013
Modified Vecchietti's vaginoplasty with Remeex system in patient with chronic graft-versus-host disease.
Melado Vidales L Muñoz M Santisteban Padro J
Open Journal of Obstetrics and Gynecology, 2, 85-88, 2012.
Physical Strain and Urgent Need for Ergonomic Training Among Gynecologic Oncologists who Perform Minimally Invasive Surgery.
Franasiak JM Ko E Kidd J Alvarez-Secord A Bell M Boggess J Gehrig P
Gynecol Oncol, 126:437, 42, 2012.
Is there a benefit for surgery in endometrioma-associated infertility?
Ruiz-Flores FJ García-Velasco JA
Curr Opin Obstet Gynecol. 24:136-40, 2012.
Do inclusive trauma systems improve outcomes after renal trauma?
Vanni AJ Hotaling J Hamlat C Jurkovich GJ Voelzke BB
J Trauma Acute Care Surg, 72(2), 385-9, 2012.
A national study of trauma level designation and renal trauma outcomes.
Hotaling J Wang J Sorensen MD Rivara FP Gore JL Jurkovich J McClung C Wessells H Voelzke BB
J Urol, 187(2), 536-41, 2012.
Conservative management vs early surgery for high grade pediatric renal trauma--do nephrectomy rates differ?
Jacobs MA Hotaling J Mueller BA Koyle M Rivara F Voelzke BB
J Urol, 187(5), 1817-22, 2012.
Analysis of diagnostic angiography and angioembolization in the acute management of renal trauma using a national data set.
Hotaling J Sorensen MD Smith TG 3rd Rivara FP Wessells H Voelzke BB
J Urol, 185(4), 1316-20, 2011.
Effect of collecting duct histology on renal cell cancer outcome.
Wright JL Risk MC Hotaling J Lin DW
J Urol, 182(6), 2595-9, 2009.
Surgery for the removal of endometriomas before in vitro fertilization does not increase implantation and pregnancy rates.
García-Velasco JA Arici A
Fertil Steril. 81:1206, 2004.
Removal of endometriomas before in vitro fertilization does not improve fertility outcomes: a matched, case-control study.
García-Velasco JA Mahutte NG Corona J Zúñiga V Gilés J Arici A Pellicer A
Fertil Steril. 81:1194-7, 2004
Bilateral partial oophorectomy in the management of severe ovarian hyperstimulation syndrome (OHSS): ovarian mutilating surgery is not an option in the management of severe OHSS.
Bellver J Escudero E Pellicer A
Hum Reprod, 18:1363-7, 2003.
Erectile dysfunction after radical prostatectomy: hemodynamic profiles and their correlation with the recovery of erectile function
Mulhall JP Slovick R Hotaling J Aviv N Valenzuela R Waters WB Flanigan RC
J Urol, 167(3), 1371-5, 2002.
Chronology of venous leak development following radical prostatectomy.
Hotaling J Mulhall JP
J Urol, 16(4), 1055A, 1999.
Correlation of follicular diameter with oocyte recovery and maturity at the time of transvaginal aspiration
Scott RT Hofmann GE Muasher SJ Acosta AA Kreiner DK Rosenwaks Z
J In Vitro Fertil Embryo Transfer, 6:73, 1989
A prospective randomized comparison of single and double lumen needles for transvaginal follicular aspiration.
Scott RT Hofmann GE Muasher SJ Acosta AA Kreiner DK Rosenwaks Z
J In Vitro Fert Embryo Transfer, 6:98, 1989.

ESHRE 2020
Meseguer M Presented at the 36th annual meeting of the European Society of Human Reproduction and Embryology Copenhagen,Denmark IVF laboratory O-197 A full automated AI based Algorithm for prediction of implantation based on the first 24 hours of embryo development Presented at 75th American Society of Reproductive Medicine Scientific Congress
Díaz-García C Garcia Camuñas Marzal A Soriano MJ Subira J garcia belda A Pellicer A Presented at the 36th annual meeting of the European Society of Human Reproduction and Embryology Copenhagen,Denmark IVF clinical O-293 Evaluation of Time Interval Between Ovulation Trigger With Triptorelin Acetate and Oocyte Retrieval in IVF Cycles. A Randomized Controlled Trial Presented at 75th American Society of Reproductive Medicine Scientific Congress
Abdala A Elkhatib I Bayram A Arnanz A El-Damen A Lawrenz B Fatemi H De Munck N Presented at the 36th annual meeting of the European Society of Human Reproduction and Embryology Copenhagen,Denmark IVF laboratory Pre-Implantation genetics Influence of culture media on embryo developmental pattern and ploidy status: a sibling oocyte study Presented at 75th American Society of Reproductive Medicine Scientific Congress
Freitas D Teixeira Almeida A Queiroz L Carvalho R Oliveira T Santos C Abreu T Niag M Coelho G Presented at the 36th annual meeting of the European Society of Human Reproduction and Embryology Copenhagen,Denmark IVF laboratory Embryonic development and cytogenetic evaluation of apronuclear zygotes after 18 to 20 hours of in vitro fertilization Presented at 75th American Society of Reproductive Medicine Scientific Congress
Hotaling J Male fertility Sexual transmission of Covid19 and male fertility Presented at 75th American Society of Reproductive Medicine Scientific Congress
ASRM 2018
Alecsandru D Pacheco A Fabris A Barrio A Aparicio P García-Velasco J Ovarian stimulation doesn’t influence the uterine immune environment in healthy infertile women Presented at the 73rd annual meeting of the American Society of Reproductive Medicine
Perez-Albal S Aparicio Ruiz B Galan Rivas A Alegre L Meseguer M Delayed blastulation is linked with changes at early cleavage stage detected by continuous embryo monitoring Presented at the 73rd annual meeting of the American Society of Reproductive Medicine
Tejera A Alegre L Castello D Mifsud A Meseguer M Improvement in reproductive outcome through artificial oocyte activation on fertilization failure cases: a cohort study Presented at the 73rd annual meeting of the American Society of Reproductive Medicine

Surgery

Investigators working in this area

Publications from this area

Presentations from this area

ESHRE 2020

ASRM 2018