Pilar Alamá, M.D., Ph.D.

Biography

Dr. Pilar Alamá, MD PhD, is an attending gynaecologist in IVI Valencia where she serves as a physician and coordinates the medical unit of egg donation at IVI Valencia. She completed her medical school education at the University of Valencia. During her career, she was selected two times as a student collaborator in the subjects of Biochemistry and Cardiology. Dr. Pilar Alamá completed her residency training in Obstetrics and Gynecology at Hospital Universitario Dr. Peset, Valencia (Spain). She obtained her Ph.D. with Cum Laudem qualification in 2008 at the University of Valencia.

Since July 2006, she has been part of the Human Reproduction Unit of IVI Valencia where she coordinates Egg donation Unit too. She is Board member of the Ethical Committee of the Instituto Valenciano de Infertilidad. He is now a member of the Group of Work about “Genetics in Gamete Donations” of the Spanish Fertility Society (SEF).

Dr. Pilar Alamá obtained a Master’s degree in Advanced Gynaecological Endoscopic Surgery in 2007-2008, and a Master’s Degree in Medical Genetics in 2015 both in University of Valencia.

Dr. Pilar Alamá has participated in clinical research projects and has contributed to over 20 publications on assisted reproduction in peer-reviewed international journals and written more than 20 book chapters. She is Member of the Research Committee of the Instituto Valenciano de Infertilidad

She has been involved in teaching postgraduate courses since 2008; Master’s Degree in Biotechnology of Assisted Human Reproduction and Master’s Degree in Infertility: psychosocial, medical and legal aspect, both in ADEIT (University of Valencia).

Dr. Pilar Alamá has been director or co-director of 3 doctoral theses, is Member of the Research Committee of the Instituto Valenciano de Infertilidad and Board member of the Ethical Committee of the Instituto Valenciano de Infertilidad. He is now a member of the Group of Work about “Genetics in Gamete Donations” of the Spanish Fertility Society (SEF). She also serves as Global Associates for Fertility & Sterility review.

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Education and Training

MD University of Valencia, Spain. (2001)

Residency training in Obstetrics and Gynecology Hospital Universitario Dr. Peset, Valencia, Spain. (2006)

Master’s degree in Advanced Gynaecological Endoscopic Surgery University of Valencia. (2007-2008)

PhD University of Valencia (2008)

Master’s Degree in Medical Genetics University of Valencia. (2015)

Honors and recognition

ELENA LABARTA; ERNESTO BOSCH; AMPARO MERCADER; PILAR ALAMA; EMILIA MATEU; ANTONIO PELLICER. "A Higher Ovarian Response after Stimulation for IVF Is Related to a Higher Number of Euploid. Embryos".Biomed Res Int. 2017. 2017, Biomed Res Int. 2017, 13/07/2017. Tipo de producción: Artículo científico Tipo de soporte: Revista.

MARÍA CRUZ; PILAR ALAMÁ; MANUEL MUÑOZ; DIANA COLLADO; CARLOS BLANES; ENRIQUE SOLBES; ANTONIO REQUENA. Economic impact of ovarian stimulation with corifollitropin alfa versus conventional daily gonadotropins in oocyte donors: a randomized study.Reprod Biomed Online. 01/03/2017. Tipo de producción: Artículo científico

PILAR ALAMÁ. Evidence that the endometrial microbiota has an effect on implantation success or failure.Am J Obstet Gynecol. 215 - 6, pp. 684 - 703. 01/07/2016. Tipo de producción: Artículo científico Tipo de soporte: Revista

JULIO MARTÍN; Asan, Yi Y; TRINIDAD ALBEROLA; BEATRIZ RODRIGUEZ-IGLESIAS; J JIMÉNEZ-ALMAZÁN; LI Q; DU H; PILAR ALAMÁ; AMPARO RUIZ; ERNESTO BOSCH; NICOLÁS GARRIDO; CARLOS SIMÓN. Comprehensive carrier genetic test using next-generation deoxyribonucleic acid sequencing in infertile couples wishing to conceive through assisted reproductive technology. FERTIL STERIL. 104 - 5, pp. 1286 - 1293. 01/10/2015. Tipo de producción: Artículo científico Tipo de soporte: Revista

NICOLÁS GARRIDO; ERNESTO BOSCH; PILAR ALAMÁ; AMPARO RUIZ. The time to prevent mendelian genetic diseases from donated or own gametes has come.FERTIL STERIL. 104 - 4, pp. 833 - 835. 01/05/2015. Tipo de producción: Artículo científico Tipo de soporte: Revista.

Publications

Medroxyprogesterone acetate is a useful alternative to a gonadotropin-releasing hormone antagonist in oocyte donation: a randomized, controlled trial.
Giles J, Alama P, Gamiz P, Vidal C, Badia P, Pellicer A, Bosch E,

Fertil Steril. Apr. 2021 doi: 10.1016/j.fertnstert.2021.02.036

Medroxyprogesterone acetate is a useful alternative to a gonadotropin-releasing hormone antagonist in oocyte donation: a randomized, controlled trial
Giles J, Alama P, Gamiz P, Vidal C, Badia P, Pellicer A, Bosch E,

Fertil Steril. Apr. 2021 doi: 10.1016/j.fertnstert.2021.02.036

Impact of low serum progesterone levels on the day of embryo transfer on pregnancy outcome: a prospective cohort study in artificial cycles with vaginal progesterone
Labarta E, Mariani G, Paolelli S, Rodriguez-Varela C, Vidal C, Giles J, Bellver J, Cruz F, Marzal A, Celada P, Olmo I, Alama P, Remohi J, Bosch E,

Hum Reprod. 18-Feb. 2021 doi: 10.1093/humrep/deaa322

Single-cell transcriptomic atlas of the human endometrium during the menstrual cycle
Wang W, Vilella F, Alama P, Moreno I, Mignardi M, Isakova A, Pan W, Simon C, Quake S R,

Nat Med. Oct. 2020 doi: 10.1038/s41591-020-1040-z

Endometrial Liquid Biopsy Provides a miRNA Roadmap of the Secretory Phase of the Human Endometrium
Grasso A, Navarro R, Balaguer N, Moreno I, Alama P, Jimenez J, Simon C, Vilella F,

J Clin Endocrinol Metab. Mar. 2020 doi: 10.1210/clinem/dgz146

Single-cell RNA sequencing of oocytes from ovarian endometriosis patients reveals a differential transcriptomic profile associated with lower quality
Ferrero H, Corachan A, Aguilar A, Quinonero A, Carbajo-Garcia M C, Alama P, Tejera A, Taboas E, Munoz E, Pellicer A, Dominguez F,

Hum Reprod. 8-Jul. 2019 doi: 10.1093/humrep/dez053

iTRAQ comparison of proteomic profiles of endometrial receptivity
Perez-Deben S, Bellver J, Alama P, Salsano S, Quinonero A, Sebastian-Leon P, Diaz-Gimeno P, Dominguez F,

J Proteomics. 15-Jul. 2019 doi: 10.1016/j.jprot.2019.103381

Corrigendum to "A Higher Ovarian Response after Stimulation for IVF Is Related to a Higher Number of Euploid Embryos"
Labarta E, Bosch E, Mercader A, Alama P, Mateu E, Pellicer A,

Biomed Res Int. 2017 doi: 10.1155/2017/1718068

A Higher Ovarian Response after Stimulation for IVF Is Related to a Higher Number of Euploid Embryos
Labarta E, Bosch E, Mercader A, Alama P, Mateu E, Pellicer A,

Biomed Res Int. 2017 doi: 10.1155/2017/5637923

Economic impact of ovarian stimulation with corifollitropin alfa versus conventional daily gonadotropins in oocyte donors: a randomized study
Cruz M, Alama P, Muñoz M, Collado D, Blanes C, Solbes E, Requena A,

Reprod Biomed Online. Jun. 2017 doi: 10.1016/j.rbmo.2017.03.003

Evidence that the endometrial microbiota has an effect on implantation success or failure
Moreno I, Codoner F M, Vilella F, Valbuena D, Martinez-Blanch J F, Jimenez-Almazan J, Alonso R, Alama P, Remohi J, Pellicer A, Ramon D, Simon C,

Am J Obstet Gynecol. 2016 Dec. doi: 10.1016/j.ajog.2016.09.075

Comprehensive carrier genetic test using next-generation deoxyribonucleic acid sequencing in infertile couples wishing to conceive through assisted reproductive technology
Martin J, Asan, Yi Y, Alberola T, Rodriguez-Iglesias B, Jimenez-Almazan J, Li Q, Du H, Alama P, Ruiz A, Bosch E, Garrido N, Simon C,

Fertil Steril. 2015 Nov. doi: 10.1016/j.fertnstert.2015.07.1166

The time to prevent mendelian genetic diseases from donated or own gametes has come
Garrido N, Bosch E, Alama P, Ruiz A,

Fertil Steril. 2015 Oct. doi: 10.1016/j.fertnstert.2015.06.047

Day-3 embryo metabolomics in the spent culture media is altered in obese women undergoing in vitro fertilization
Bellver J, De Los Santos M J, Alama P, Castello D, Privitera L, Galliano D, Labarta E, Vidal C, Pellicer A, Dominguez F,

Fertil Steril. 2015 Jun. doi: 10.1016/j.fertnstert.2015.03.015

The time to prevent mendelian genetic diseases from donated or own gametes has come.
Garrido N, Bosch E, Alama P, Ruiz A,

Fertil Steril. 2015 doi:

The accuracy and reproducibility of the endometrial receptivity array is superior to histology as a diagnostic method for endometrial receptivity
Diaz-Gimeno P, Ruiz-Alonso M, Blesa D, Bosch N, Martinez-Conejero J A, Alama P, Garrido N, Pellicer A, Simon C,

Fertil Steril. 2013 Feb. doi: 10.1016/j.fertnstert.2012.09.046

The follicular hormonal profile in low-responder patients undergoing unstimulated cycles: Is it hypoandrogenic?
de los Santos M J, Garcia-Laez V, Beltran D, Labarta E, Zuzuarregui J L, Alama P, Gamiz P, Crespo J, Bosch E, Pellicer A,

Hum Reprod. 2013 Jan. doi: 10.1093/humrep/des349

GnRH analogies in the prevention of Ovarian Hyperstimulation Syndrome.
Alama P, Bellver J, Vidal C, Giles J,

Int J Endocrinol Metab. 2013 doi:

GnRH analogues in the prevention of ovarian hyperstimulation syndrome.
Alama P, Bellver J, Vidal C, Giles J,

International Journal of Endocrinology and Metabolism. 2013 doi:

PGE2and PGF2? Concentrations in Human Endometrial Fluid as Biomarkers for Embryonic Implantation.
Vilella F, Ramirez L, Berlanga O, Martinez S, Alama P, Meseguer M, Pellicer A, Simon C,

J Clin Endocrinol Metab. 2013 doi:

Moderate ovarian stimulation does not increase the incidence of human embryo chromosomal abnormalities in in vitro fertilization cycles
Labarta E, Bosch E, Alama P, Rubio C, Rodrigo L, Pellicer A,

J Clin Endocrinol Metab. 2012 Oct. doi: 10.1210/jc.2012-1738

Cumulative newborn rates increase with the total number of transferred embryos according to an analysis of 15,792 ovum donation cycles
Garrido N, Bellver J, Remohi J, Alama P, Pellicer A,

Fertil Steril. 2012 Aug. doi: 10.1016/j.fertnstert.2012.04.039

Endometrial receptivity is affected in women with high circulating progesterone levels at the end of the follicular phase: a functional genomics analysis
Labarta E, Martinez-Conejero J A, Alama P, Horcajadas J A, Pellicer A, Simon C, Bosch E,

Hum Reprod. 2011 Jul. doi: 10.1093/humrep/der126

Endometrial gene expression in the window of implantation is altered in obese women especially in association with polycystic ovary syndrome
Bellver J, Martinez-Conejero J A, Labarta E, Alama P, Melo M A, Remohi J, Pellicer A, Horcajadas J A,

Fertil Steril. 2011 Jun. doi: 10.1016/j.fertnstert.2011.03.021

Endometrial gene expressions in the window of implantation is altered in obese women especially in association with polycystic ovary syndrome
Bellver J, Martinez-Conejero JA, Labarta E, Alama P, Melo MA, Remohi J, Pellicer A, Horcajadas J A,

Fertil Steril. 2011 doi:

GnRH agonist versus recombinant HCG in an oocyte donation programme: a randomized, prospective, controlled, assessor-blind study.
Melo M, Busso CE, Bellver J, Alama P, Garrido N, Meseguer M, Pellicer A, Remohi J,

RBM Online. 2009 doi:

Fresh human orthotopic ovarian cortex transplantation: long-term results
Sanchez M, Alama P, Gadea B, Soares S R, Simon C, Pellicer A,

Hum Reprod. 2007 Mar. doi: 10.1093/humrep/del440

Fresh human orthotopic ovarian córtex transplantation: long-term results.
Sanchez M, Alama P, Gadea B, Soares S R, Simon C, Pellicer A,

Hum Reprod. 2007 doi:

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Presentations

Giles J Cruz M Alamá P Laura Caracena Vidal C Bosch E P-863 PROGNOSTIC FACTORS OF OVARIAN RESPONSE AFTER FOLLICULAR PROTOCOL WITH MPA TRIGGER WITH GnRH AGONIST.. Presented at 76th American Society of Reproductive Medicine Scientific Congress, Virtual congress, October 17-21,2020

Giles J Alama P Gamiz P Vidal C Badia P Bosch E O-010 Can serve Medroxiprogesterone acetate (MPA) as gonadotropin adjuvant instead of GnRH antagonist during ovarian stimulation (OS) in oocyte donation (OD) cycles trigger with GnRH agonist? . Presented at the 36th annual meeting of the European Society of Human Reproduction and Embryology, Copenhagen,Denmark, July 5-8, 2020

Labarta E Mariani G Paolelli S Vidal C Giles J Bellver J Cruz F Marzal A Celada p Olmo I Alamá P Remohí J Bosch E O-173: A large prospective trial in unselected population confirms that low serum progesterone on the day of embryo transfer impairs pregnancy outcome in artificial cycles.. Presented at the 74th Scientific Congress & Expo of the American Society for Reproductive Medicine, Denver, CO, USA, 23-26 June 2019

Bosch E Alamá P Romero J Mari M Labarta E O-239: Follicular steroidogenesis in GnRH antagonist ovarian stimulation cycles with r-FSH vs. hp-HMG. A randomized controlled trial. Presented at the 74th Scientific Congress & Expo of the American Society for Reproductive Medicine, Denver, CO, USA, 23-26 June 2019

Ferrero H Corachán A Quiñonero A Carbajo-García C Alamá P Tejera A Taboas E Muñoz E Pellicer A Domínguez F NGS of Oocytes from Endometriosis Patients Reveals a Differential Transcriptomic Pattern. Presented at the 34rd annual meeting of the European Society of Human Reproduction and Embryology, Barcelona, Spain, March 12-16, 2019

Labarta E Mariani Paolelli S Vidal C Giles J Marzal A Bellver J Cruz F Olmo I Alama P Celada P Bosch E Impact of serum progesterone levels on the day of embryo transfer in artificial endometrial preparation cycles on the ongoing pregnancy rate. An interim analysis. Presented at the 73rd annual meeting of the American Society of Reproductive Medicine, San Antonio, Texas, October 6-10, 2018

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