ESHRE PGT Consortium data collection XXI: PGT analyses in 2018.
Spinella F, Bronet F, Carvalho F, Coonen E, De Rycke M, Rubio C, Goossens V, Van Montfoort A
Hum Reprod Open. 2023 Apr 19;2023(2):hoad010. doi: 10.1093/hropen/hoad010. eCollection 2023.. 2023
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Mosaic results after preimplantation genetic testing for aneuploidy may be accompanied by changes in global gene expression.
Martin A, Mercader A, Dominguez F, Quiñonero A, Perez M, Gonzalez-Martin R, Delgado A, Mifsud A, Pellicer A, De Los Santos MJ
Front Mol Biosci. 2023 Apr 14;10:1180689. doi: 10.3389/fmolb.2023.1180689. eCollection 2023.. 2023
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Antimüllerian hormone (AMH) and age as predictors of preimplantation genetic testing for aneuploidies (PGT-A) cycle outcomes and blastocyst quality on day 5 in women undergoing in vitro fertilization (IVF).
Arnanz A, Bayram A, Elkhatib I, Abdala A, El-Damen A, Patel R, Lawrenz B, Melado L, Fatemi H, De Munck N
J Assist Reprod Genet. 2023 May 5. doi: 10.1007/s10815-023-02805-z. Online ahead of print.. 2023
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The Ratio of Serum Progesterone (P4) to the Number of Follicles (P4/follicle) is a More Objective Parameter for Euploidy Rate as Compared to Systemic Progesterone Levels.
Ali KIA, Lawrenz B, Shanker U, Ruiz F, El-Damen A, ElKhatib I, Fatemi H, De Munck N
Reprod Sci. 2023 May 16. doi: 10.1007/s43032-023-01258-0. Online ahead of print.. 2023
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BOLOGNA VS POSEIDON CRITERIA AS PREDICTORS OF THE LIKELIHOOD OF OBTAINING AT LEAST ONE EUPLOID EMBRYO IN POOR OVARIAN RESPONSE: AN ANALYSIS OF 6,889 CYCLES
Reig A, Garcia-Velasco JA, Seli E
Fertility and SterilityAvailable online 13 May 2023 In press. 2023
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Reply of the Authors: Recurrent implantation failure: reality or a statistical mirage?
Paul Pirtea MD a, Marcelle I Cedars MD b, Kate Devine MD c, Baris Ata MD, PhD d e, Jason Franasiak MD f, Catherine Racowsky PhD a, Jim Toner MD, PhD g, Richard T Scott MD f, Dominique de Ziegler MD a, Kurt T Barnhart
Fertility and SterilityAvailable online 14 April 2023 In press. 2023
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Opening the black box: why do euploid blastocysts fail to implant? A systematic review and meta-analysis.
Cimadomo D, Rienzi L, Conforti A, Forman E, Canosa S, Innocenti F, Poli M, Hynes J, Gemmell L, Vaiarelli A, Alviggi C, Ubaldi FM, Capalbo A
Hum Reprod Update. 2023 May 16:dmad010. doi: 10.1093/humupd/dmad010. Online ahead of print.. 2023
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The first mitotic division: a perilous bridge connecting the zygote and the early embryo
Giovanni Coticchio, Danilo Cimadomo, Greta Chiara Cermisoni, Laura Rienzi, Enrico Papaleo, Filippo Maria Ubaldi, Andrea Borini, Lucia De Santis
Human Reproduction, Volume 38, Issue 6, June 2023, Pages 1019–1027, https://doi.org/10.1093/humrep/dead067. 2023
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The Distribution of High and Low-Level Mosaicism and Maternal Age: Lessons and Hesitations
Stephanie Willson, Thomas Molinaro
F&S Reports Available online 15 June 2023 In press. 2023
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Preimplantation genetic testing for aneuploidy is not related to adverse obstetric and neonatal outcomes in singleton pregnancies.
Cozzolino M, Nardini Cecchino G, Garcia Velasco JA, Pellicer N, Galliano D, Pellicer A
Hum Reprod. 2023 Jun 19:dead123. doi: 10.1093/humrep/dead123. Online ahead of print.. 2023
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Improved clinical utility of preimplantation genetic testing through the integration of ploidy and common pathogenic microdeletions analyses.
Caroselli S, Figliuzzi M, Picchetta L, Cogo F, Zambon P, Pergher I, Girardi L, Patassini C, Poli M, Bakalova D, Cimadomo D, Findikli N, Coban O, Serdarogullari M, Favero F, Bortolato S, Anastasi A, Capodanno F, Gallinelli A, Brancati F, Rienzi L, Ubaldi FM, Jimenez-Almazán J, Blesa-Jarque D, Miravet-Valenciano J, Rubio C, Simòn C, Capalbo A
Hum Reprod. 2023 Feb 22:dead033. doi: 10.1093/humrep/dead033. Online ahead of print.. 2023
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Investigating the significance of segmental aneuploidy findings in preimplantation embryos
Ludovica Picchetta, Christian S Ottolini, Helen C O'Neill, Antonio Capalbo
F S Sci. 2023 Mar 20:S2666-335X(23)00015-0. doi: 10.1016/j.xfss.2023.03.004. Online ahead of print.. 2023
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Towards Automation in IVF: Pre-Clinical Validation of a Deep Learning-Based Embryo Grading System during PGT-A Cycles.
Cimadomo D, Chiappetta V, Innocenti F, Saturno G, Taggi M, Marconetto A, Casciani V, Albricci L, Maggiulli R, Coticchio G, Ahlström A, Berntsen J, Larman M, Borini A, Vaiarelli A, Ubaldi FM, Rienzi L
J Clin Med. 2023 Feb 23;12(5):1806. doi: 10.3390/jcm12051806.. 2023
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Update on preimplantation genetic testing for aneuploidy and outcomes of embryos with mosaic results.
Dahdouh EM, Mourad AM, Balayla J, Sylvestre C, Brezina PR, Kutteh WH, Picchetta L, Capalbo A, Garcia-Velasco JA
Minerva Obstet Gynecol. 2022 Oct 18. doi: 10.23736/S2724-606X.22.05166-1. Online ahead of print.. 2022
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Limits imposed by the experimental design of a large prospective non-inferiority study on PGT-A invalidate many of the conclusions.
Scott RT, de Ziegler D, Pirtea P, Jalas C
Hum Reprod. 2022 Oct 26:deac224. doi: 10.1093/humrep/deac224. Online ahead of print.. 2022
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ESHRE survey results and good practice recommendations on managing chromosomal mosaicism.
ESHRE Working Group on Chromosomal Mosaicism, De Rycke M, Capalbo A, Coonen E, Coticchio G, Fiorentino F, Goossens V, Mcheik S, Rubio C, Sermon K, Sfontouris I, Spits C, Vermeesch JR, Vermeulen N, Wells D, Zambelli F, Kakourou G
Hum Reprod Open. 2022 Nov 7;2022(4):hoac044. doi: 10.1093/hropen/hoac044. eCollection 2022.. 2022
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On the reproductive capabilities of aneuploid human preimplantation embryos.
Capalbo A, Poli M, Jalas C, Forman EJ, Treff NR
Am J Hum Genet. 2022 Sep 1;109(9):1572-1581. doi: 10.1016/j.ajhg.2022.07.009.. 2022
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A randomized, non-inferiority trial on the DuoStim strategy in PGT-A cycles
María Cerrillo, Gustavo N Cecchino, MónicaToribio, María JGarcía-Rubio, Juan AGarcía-Velasco
Reproductive BioMedicine Online Available online 25 November 2022 In press. 2022
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Correction: Embryos of Robertsonian Translocation Carriers Exhibit a Mitotic Interchromosomal Effect That Enhances Genetic Instability during Early Development.
Alfarawati S, Fragouli E, Colls P, Wells D
PLoS Genet. 2022 Aug 29;18(8):e1010377. doi: 10.1371/journal.pgen.1010377. eCollection 2022 Aug.. 2022
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Avoid mixing apples and oranges: blastocysts diagnosed with uniform whole chromosome aneuploidies are reproductively incompetent and their transfer is harmful.
Capalbo A, Cimadomo D, Rienzi L, Garcìa-Velasco JA, Simòn C, Ubaldi FM
Hum Reprod. . 2022
doi: 10.1093/humrep/deac149
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Mosaic Embryo Transfer: A cautionary tale
Jason M Franasiak
F&S Reports. 2022
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Switching to testicular sperm after a previous ICSI failure with ejaculated sperm significantly improves blastocyst quality without increasing aneuploidy risk.
Hervas I, Gil Julia M, Rivera-Egea R, Navarro-Gomezlechon A, Mossetti L, Garrido N
J Assist Reprod Genet.. Aug. 2022
doi: 10.1007/s10815-022-02595-w. Online ahead of print.
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Impact of parental chromosomal polymorphisms on the incidence of congenital anomalies and perinatal complications in a cohort of newborns conceived after ICSI + PGT-A.
Rodriguez F, Cruz M, Requena A
Reprod Biol Endocrinol.. Sep. 2022
doi: 10.1186/s12958-022-01012-2.
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The chances of obtaining a euploid embryo and subsequent live birth remain consistent with national age-based rates after an in vitro fertilization cycle that produced only aneuploid embryos.
Herlihy NS, Klimczak AM, Cheung JKW, Seli E, Scott RT Jr
Fertil Steril. 2022 Jun 9:S0015-0282(22)00335-1. Online ahead of print. 2022
doi: 10.1016/j.fertnstert.2022.05.026
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We know to err (meiotically) is human, but do paternal factors impact paternal aneuploidy?
Andres Reig, Jason M Franasiak
Fertility and Sterility. Available online 30 June 2022 In Press, Corrected Proof. 2022
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Predicting embryonic aneuploidy rate in IVF patients using whole-exome sequencing.
Sun S, Miller M, Wang Y, Tyc KM, Cao X, Scott RT Jr, Tao X, Bromberg Y, Schindler K, Xing J
Hum Genet. 2022
doi: 10.1007/s00439-022-02450-z
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Avoiding Asherman’s syndrome: refining our approach to uterine evacuation
Martin FFreedman, William DSchlaff
Fertility and Sterility . 2021
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The cyto-protective effects of LH on ovarian reserve and female fertility during exposure to gonadotoxic alkylating agents in an adult mouse model.
Del Castillo LM, Buigues A, Rossi V, Soriano MJ, Martinez J, De Felici M, Lamsira HK, Di Rella F, Klinger FG, Pellicer A, Herraiz S
Hum Reprod. 2021
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PGT-A for recurrent pregnancy loss: evidence is growing but the issue is not resolved.
Dahdouh EM, Balayla J, Garcia-Velasco JA, Kutteh WH
Hum Reprod. 2021
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Consistency in rates of diagnosis of embryonic mosaicism, segmental abnormalities, and "no call" results among experienced embryologists performing preimplantation genetic testing for aneuploidy.
Osman EK, Neal SA, Tiegs AW, Hanson BM, Kim JG, Franasiak JM, Scott RT Jr
F S Rep. 2021
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Association between clinical and IVF laboratory parameters and miscarriage after single euploid embryo transfers.
Del Carmen Nogales M, Cruz M, de Frutos S, Martínez EM, Gaytán M, Ariza M, Bronet F, Garcia-Velasco JA
Reprod Biol Endocrinol. 2021
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The concordance rates of an initial trophectoderm biopsy with the rest of the embryo using PGTseq, a targeted next-generation sequencing platform for preimplantation genetic testing-aneuploidy
Julia Kim, Xin Tao Julia Kim MD, MPHab Xin Tao PhDc, Michael Cheng MSa Ayesha Steward MSa, Vanessa Guo BAc, Yiping Zhan PhDc, Richard T Scott Jr MD, HCLDab, Chaim Jalas c
Fertility and Sterility. 2021
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Mosaic embryos: hiding in plain sight.
Scott, R T
Fertil Steril. Jul. 2021
doi: 10.1016/j.fertnstert.2021.04.039
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Parameters of poor prognosis in preimplantation genetic testing for monogenic disorders.
Van, Der, Kelen, A, Santos-Ribeiro, S, De, Vos, A, Verdyck, P, De, Rycke, M, Berckmoes, V, Tournaye, H, Blockeel, C, De, Vos, M, Hes, FJ, Keymolen, K, Verpoest, W
Hum Reprod. Jun. 2021
doi: 10.1093/humrep/deab136
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Non-invasive PGT
Vendrell, X, Escriba, MJ
Med Reprod y Embr Clínica. May. 2021
doi: 10.1016/j.medre.2021.100101
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Frequent loss of heterozygosity in CRISPR-Cas9-edited early human embryos.
Alanis-Lobato, G, Zohren, J, McCarthy, A, Fogarty, NME, Kubikova, N, Hardman, E, Greco, M, Wells, D, Turner, JMA, Niakan, KK
Proc. Natl. Acad. Sci. USA. Apr. 2021
doi: 10.1073/pnas.2004832117
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Elevated serum progesterone does not impact euploidy rates in PGT-A patients.
Pardiñas, ML, Nohales, M, Labarta, E, De Los Santos, JM, Mercader, A, Remohi, J, Bosch, E, De Los Santos, MJ
J Assist Reprod Genet. May. 2021
doi: 10.1007/s10815-021-02197-y
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Embryos with mosaic results: busting the myth!
Dahdouh, EM, Garcia-Velasco, JA
Reprod BioMed Online. Apr. 2021
doi: 10.1016/j.rbmo.2021.04.015
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Rescuing monopronucleated-derived human blastocysts: a model to study chromosomal topography and fingerprinting.
Soler, N, Bautista-Llacer, R, Escrich, L, Oller, A, Grau, N, Tena, R, Insua, MF, Ferrer, P, Escriba, MJ, Vendrell, X
Fertil Steril. Apr. 2021
doi: 10.1016/j.fertnstert.2021.03.038
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Noninvasive prenatal testing in women undergoing in vitro fertilization with preimplantation genetic testing.
Klimczak, AM, Seli, E, Scott, RT
Curr Opin Obstet Gynecol. Mar. 2021
doi: 10.1097/GCO.0000000000000707
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Evaluation of genome-wide DNA methylation profile of human embryos with different developmental competences.
Yang, M, Tao, X, Scott, K, Zhan, Y, Scott, RT, Seli, E
Hum Reprod. Apr. 2021
doi: 10.1093/humrep/deab074
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Preimplantation genetic testing to evaluate for mitochondrial deoxyribonucleic acid disease and aneuploidy: a two-birds-with-one-stone approach
Hanson, BM, Seli, E
Fertil Steril. Apr. 2021
doi: 10.1016/j.fertnstert.2021.03.006
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Clinical application of sequencing-based methods for parallel preimplantation genetic testing for mitochondrial DNA disease and aneuploidy
Spath, K, Babariya, D, Konstantinidis, M, Lowndes, J, Child, T, Grifo, JA, Poulton, J, Wells, D
Fertil Steril. Mar. 2021
doi: 10.1016/j.fertnstert.2021.01.026
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Noninvasive preimplantation genetic testing for aneuploidy exhibits high rates of deoxyribonucleic acid amplification failure and poor correlation with results obtained using trophectoderm biopsy
Hanson, BM, Tao, X, Hong, KH, Comito, CE, Pangasnan, R, Seli, E, Jalas, C, Scott, RT
Fertil Steril. Mar. 2021
doi: 10.1016/j.fertnstert.2021.01.028
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Noninvasive preimplantation genetic testing for aneuploidy in spent culture medium as a substitute for trophectoderm biopsy
Rubio, C, Racowsky, C, Barad, DH, Scott, RT, Simon, C
Fertil Steril. Mar. 2021
doi: 10.1016/j.fertnstert.2021.02.045
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Serum anti-Müllerian hormone levels are not associated with aneuploidy rates in human blastocysts.
Pipari, A, Guillen, A, Cruz, M, Pacheco, A, Garcia-Velasco, JA
Reprod BioMed Online. Apr. 2021
doi: 10.1016/j.rbmo.2021.03.006
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A Natural Xenogeneic Endometrial Extracellular Matrix Hydrogel Toward Improving Current Human in vitro Models and Future in vivo Applications
Lopez-Martinez, S, Campo, H, de Miguel-Gomez, L, Faus, A, Navarro, A T, Diaz, A, Pellicer, A, Ferrero, H, Cervello, I,
Front Bioeng Biotechnol. Mar. 2021
doi: 10.3389/fbioe.2021.639688
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Clinical application of sequencing-based methods for parallel preimplantation genetic testing for mitochondrial DNA disease and aneuploidy
Spath, K, Babariya, D, Konstantinidis, M, Lowndes, J, Child, T, Grifo, J A, Poulton, J, Wells, D,
Fertil Steril. Mar. 2021
doi: 10.1016/j.fertnstert.2021.01.026
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Noninvasive preimplantation genetic testing for aneuploidy exhibits high rates of deoxyribonucleic acid amplification failure and poor correlation with results obtained using trophectoderm biopsy
Hanson, B M, Tao, X, Hong, K H, Comito, C E, Pangasnan, R, Seli, E, Jalas, C, Scott, R T,
Fertil Steril. Mar. 2021
doi: 10.1016/j.fertnstert.2021.01.028
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Endometrial scratching can be offered outside clinical research setting: let us show you why
Vitagliano, A, Di Spiezio Sardo, A, Noventa, M, Carugno, J, Cicinelli, E, Pacheco, A, Vitale, S G, Campo, R, Lagana, A S, Haimovich, S, Cozzolino, M, Greco, P,
Hum Reprod. Apr. 2021
doi: 10.1093/humrep/deab060
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Fetal nondiabetic-macrosomia: risk factors for pregnancy adverse outcome and comparison of two growth curves in the prediction of cesarean section
Simeone, S, Vannuccini, S, Proietto, R, Serena, C, Ottanelli, S, Rambaldi, M P, Lisi, F, Clemenza, S, Comito, C, Cozzolino, M, Petraglia, F, Mecacci, F,
J Matern Fetal Neonatal Med. 24-Feb. 2021
doi: 10.1080/14767058.2021.1888918
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Uterine natural killer cells: from foe to friend in reproduction
Diaz-Hernandez, I, Alecsandru, D, Garcia-Velasco, J A, Dominguez, F,
Hum Reprod Update. 2-Feb. 2021
doi: 10.1093/humupd/dmaa062
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Early Pregnancy Outcomes in Fresh Versus Deferred Embryo Transfer Cycles for Endometriosis-Associated Infertility: A Retrospective Cohort Study
Tan, J, Cerrillo, M, Cruz, M, Cecchino, G N, Garcia-Velasco, J A,
J Clin Med. Jan. 2021
doi: 10.3390/jcm10020344
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Current Controversies in Prenatal Diagnosis 3: Gene editing should replace embryo selection following PGD
Wells, D, Vermeesch, J R, Simpson, J L,
Prenat Diagn. Apr. 2019
doi: 10.1002/pd.5442
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Three-Dimensional Angiogenic Evaluation of the Effect of Mifepristone in early gestation: pilot study
Pellicer-Iborra, B, Herraiz, S, Morales, A, Martinez, S, Garrido, N, Pellicer, A,
Gynecol Obstet. 2018
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Patients with endometriosis have aneuploidy rates equivalent to their age-matched peers in the in vitro fertilization population
Juneau, C, Kraus, E, Werner, M D, Franasiak, J M, Morin, S J, Patounakis, G, Molinaro, T A, de Ziegler, D, Scott, R T,
Fertil Steril. Aug. 2017
doi: 10.1016/j.fertnstert.2017.05.038
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Analysis of implantation and ongoing pregnancy rates following the transfer of mosaic diploid-aneuploid blastocysts.
Fragouli, E, Alfarawati, S, Spath, K, Babariya, D, Tarozzi, N, Borini, A, Wells, D,
Hum Genet. 2017
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Detection of segmental aneuploidy and mosaicism in the human preimplantation embryo: technical considerations and limitations.
Treff, N, Franasiak, J M,
Fertil Steril. 2017
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Survey of Fertility Preservation Options Available to Patients With Cancer Around the Globe. J Glob Oncol. 4, pp. 1 - 16. 28/06/2017.
Rashedi, AS, de, Roo, SF, Ataman, LM, Edmonds, ME, Silva, AA, Scarella, A, Horbaczewska, A, Anazodo, A, Arvas, A, Ramalho, de, Carvalho, B, Sartorio, C, Beerendonk, CCM, Diaz-Garcia, C, Anazodo, A,
2017
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Pathophysiologic processes have an impact on the plasma metabolomic signature of endometriosis patients
Vicente-Munoz, S, Morcillo, I, Puchades-Carrasco, L, Paya, V, Pellicer, A, Pineda-Lucena, A,
Fertil Steril. Dec. 2016
doi: 10.1016/j.fertnstert.2016.09.014
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Automatic time-lapse instrument is superior to single-point morphology observation for selecting viable embryos: retrospective study in oocyte donation
Aparicio-Ruiz, B, Basile, N, Perez Albala, S, Bronet, F, Remohi, J, Meseguer, M,
Fertil Steril. Nov. 2016
doi: 10.1016/j.fertnstert.2016.07.1117
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The why, the how and the when of PGS 2.0: current practices and expert opinions of fertility specialists, molecular biologists, and embryologists
Sermon, K, Capalbo, A, Cohen, J, Coonen, E, De Rycke, M, De Vos, A, Delhanty, J, Fiorentino, F, Gleicher, N, Griesinger, G, Grifo, J, Handyside, A, Harper, J, Kokkali, G, Mastenbroek, S, Meldrum, D, Meseguer, M, Montag, M, Munne, S, Rienzi, L, Rubio, C, Scott, K, Scott, R T, Simon, C, Swain, J, Treff, N, Ubaldi, F, Vassena, R, Vermeesch, J R, Verpoest, W, Wells, D, Geraedts, J,
Mol Hum Reprod. Aug. 2016
doi: 10.1093/molehr/gaw034
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The challenge of embryonic mosaicism in preimplantation genetic screening
Scott, R T, Galliano, D,
Fertil Steril. May. 2016
doi: 10.1016/j.fertnstert.2016.01.007
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Kinetics of the early development of uniparental human haploid embryos
Escriba, M J, Escrich, L, Galiana, Y, Grau, N, Galan, A, Pellicer, A,
Fertil Steril. May. 2016
doi: 10.1016/j.fertnstert.2015.12.139
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A randomized and blinded comparison of qpcr and NGS based detection of aneuploidy in a cell line mixture model of blastocyst biopsy mosaicism.
Goodrich, D, Tao, X, Bohrer, C, Lonczak, A, Xing, T, Zimmerman, R, Zhan, Y, Scott, R T, Treff, NR, Scott, R T,
Hum Reprod. 2016
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Aneuploidy screening by array comparative genomic hybridization improves success rates of in vitro fertilization: A multicenter Indian study.
Kotdawala, A, Patel, D, Herrero, J, Khajuria, R, Mahajan, N, Banker, M,
J Hum Reprod Sci. 2016
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Causes and estimated incidences of sex-chromosome misdiagnosis in preimplantation genetic diagnosis of aneuploidy.
Ravichandran, K, Guzman, L, Escudero, T, Zheng, X, Colls, P, Jordan, A, Cohen, J, Wells, D, Munne, S, Wells, D,
RBM Online. 2016
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Challenges facing contemporary preimplantation genetic screening.
Juneau, C, Franasiak, J M, Treff, N,
Curr Opin Obstet Gynecol. 2016
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Current controversies in prenatal diagnosis 4: preimplantation genetic screening should be routinely offered to all preimplantation genetic diagnosis cases.
Harper, J, Wells, D, Simpson, JL,
Prenat Diagn. 2016
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Development and validation of concurrent preimplantation genetic diagnosis for single gene disorders and comprehensive chromosomal aneuploidy screening without whole-genome amplification.
Zimmerman, RS, Jalas, C, Tao, X, Fedick, AM, Kim, J, Pepe, RJ, Northrop, LE, Scott, R T, Treff, NR, , Scott, R T,
Fertil Steril. 2016
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Embryonic aneuploidy does not differ among genetic ancestry according to continental origin as determined by ancestry informative markers.
Franasiak, J M, Olcha, M, Shastri, S, Molinaro, T A, Congdon, H, Treff, NR, Scott, R T,
Hum Reprod. 2016
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Embryonic aneuploidy does not differ amongst major ethnicities as determined by genotyping.
Franasiak, J M, Olcha, M, Treff, N, Scott, R T,
Hum Reprod. 2016
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Mosaicism: “survival of the fittest” versus “no embryo left behind”.
Munne, S, Grifo, J, Wells, D,
Fertil Steril. 2016
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Next Generation Sequencing Based Comprehensive Chromosome Screening in Mouse Polar Bodies, Oocytes, and Embryos.
Treff, NR, Krisher, R, Tao, X, Garnsey, H, Bohrer, C, Silva, E, Landis, J, Taylor, D, Scott, R T, Woodruff, TK, Duncan, FE, Taylor, D,
Biol Reprod. 2016
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Preimplantation genetic diagnosis for infertility.
Wells, D, Lewin, J,
Textbook of Assisted Reproductive technologies. 2016
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Preimplantation genetic diagnosis: an overview and recent advances.
Ben-Nagi, J, Serhal, P, SenGupta, S, Doye, K, Wells, D,
Obstet Gynaecol. 2016
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SNP array-based analyses of unbalanced embryos as a reference to distinguish between balanced translocation carrier and normal blastocysts.
Treff, NR, Thompson, K, Rafizadeh, M, Chow, M, Morrison, L, Tao, X, Garnsey, H, Reda, CV, Metzgar, TL, Neal, S, Jalas, C, Scott, R T, Forman, E, Reda, CV,
J Assist Reprod Genet. 2016
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Técnicas invasivas y no invasivas en el diagnóstico de embriones humanos.
Calomarde, C, Carmona, L, Guerra, I, Gutierrez, D, Santana, A, Domingo, J,
Rev Iberoam Fert Rep Hum. 2016
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Why do euploid embryos miscarry? A case-control study comparing the rate of aneuploidy within presumed euploid embryos that resulted in miscarriage or live birth using next-generation sequencing.
Maxwell, SM, Colls, P, Hodes-Wertz, B, McCulloh, DH, McCaffrey, C, Wells, D, Munne, S, Grifo, J,
Fertil Steril. 2016
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The time to prevent mendelian genetic diseases from donated or own gametes has come
Garrido, N, Bosch, E, Alama, P, Ruiz, A,
Fertil Steril. Oct. 2015
doi: 10.1016/j.fertnstert.2015.06.047
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Preimplantation genetic screening using comprehensive chromosome screening: evidence and remaining challenges
Dahdouh, E M, Balayla, J, Garcia-Velasco, J A,
Hum Reprod. Jun. 2015
doi: 10.1093/humrep/dev079
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The use of morphokinetics as a predictor of implantation: a multicentric study to define and validate an algorithm for embryo selection
Basile, N, Vime, P, Florensa, M, Aparicio Ruiz, B, Garcia-Velasco, J A, Remohi, J, Meseguer, M,
Hum Reprod. Feb. 2015
doi: 10.1093/humrep/deu331
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Systematic review on clinical outcomes following selection of human preimplantation embryos with time-lapse monitoring
Freour, T, Basile, N, Barriere, P, Meseguer, M,
Hum Reprod Update. Jan-Feb. 2015
doi: 10.1093/humupd/dmu054
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24-chromosome PCR for aneuploidy screening.
Werner, M D, Scott, R T,
Curr Opin Obstet Gynecol. 2015
doi:
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Comprehensive chromosome screening improves embryo selection: a meta-analysis.
Dahdouh, EM, Balayla, J, Garcia-Velasco, J A,
Fertil Steril. 2015
doi:
|
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Deep impact: sequencing embryo biopsy specimens at increasing depth.
Spath, K, Wells, D,
RBM Online. 2015
doi:
|
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Discordant embryonic aneuploidy testing and prenatal ultrasonography prompting androgen insensitivity syndrome diagnosis.
Franasiak, J M, Yao, X, Ashkindaze, E, Rosen, T, Scott, R T,
Obstet Gynecol. 2015
doi:
|
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Karyomapping - a comprehensive means of simultaneous monogenic and cytogenetic PGD: comparison with standard approaches in real time for Marfan syndrome.
Thornhill, AR, Handyside, AH, Ottolini, C, Natesan, SA, Taylor, J, Sage, K, Harton, G, Cliffe, K, Affara, N, Konstantinidis, M, Wells, D, Griffin, DK,
J Assist Reprod Genet. 2015
doi:
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Karyomapping allows preimplantation genetic diagnosis of a de-novo deletion undetectable using conventional PGD technology.
Gimenez, C, Sarasa, J, Arjona, C, Vilamajo, E, Martinez-Pasarell, O, Wheeler, K, Valls, G, Garcia-Guixe, E, Wells, D, Garcia-Guixe, E,
RBM Online. 2015
doi:
|
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Live births following Karyomapping of human blastocysts: experience from clinical application of the method.
Konstantinidis, M, Prates, R, Goodall, N, Fischer, J, Tecson, V, Lemma, T, Chua, B, Jordan, A, Armenti, E, Wells, D, Munne, S, Jordan, A,
RBM Online. 2015
doi:
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Routine use of next-generation sequencing for preimplantation genetic diagnosis of blastomeres obtained from embryos on day 3 in fresh in~vitro fertilization cycles.
Ukaszuk K, Pukszta, S, Wells, D, Cybulska, C, Liss, J, P?ociennik, ?, Kuczy?ski, W, Zabielska, J,
Fertil Steril. 2015
doi:
|
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The time to prevent mendelian genetic diseases from donated or own gametes has come.
Garrido, N, Bosch, E, Alama, P, Ruiz, A,
Fertil Steril. 2015
doi:
|
|
Live birth after embryo transfer in an unresponsive thin endometrium
Cruz, F, Bellver, J,
Gynecol Endocrinol. Jul. 2014
doi: 10.3109/09513590.2014.900747
|
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Increasing the probability of selecting chromosomally normal embryos by time-lapse morphokinetics analysis
Basile, N, Nogales Mdel, C, Bronet, F, Florensa, M, Riqueiros, M, Rodrigo, L, Garcia-Velasco, J A, Meseguer, M,
Fertil Steril. Mar. 2014
doi: 10.1016/j.fertnstert.2013.12.005
|
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Clinical genetic testing for male factor infertility: current applications and future directions.
Hotaling, J M, Carrell, DT,
Andrology. 2014
doi:
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Clinical utilization of a rapid low-pass whole genome sequencing technique for the diagnosis of aneuploidy in human embryos prior to implantation.
Wells, D, Kaur, K, Grifo, J, Glassner, M, Taylor, JC, Fragouli, E, Munne, S,
J Med Genet. 2014
doi:
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Comparison of array comparative genomic hybridization and quantitative real-time PCR-based aneuploidy screening of blastocyst biopsies.
Capalbo, A, Treff, , N, Cimadomo, D, Tao, X, Upham, K, Ubaldi, , F, Rienzi, L, Scott, R T,
Eur J Hum Genet. 2014
doi:
|
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Embryo aneuploidy screening with CGH arrays in the absence of implantation.
Garcia-Herrero, S, Garcia-Herrero, S, Rodrigo, L, Mateu, E, Peinado, V, Milan, M, Campos-Galindo, I, Vera, M, Mercader, A, Bronet, F, Requena, A, Simon, C, Rubio, C, Vera, M,
Médecine de la Reproduction. 2014
doi:
|
|
Embryo biopsy for aneuploidy detection in the general infertility population.
Kaser, D J, Ginsburg, ES,
Semin Reprod Med. 2014
doi:
|
|
Embryonic aneuploidy: overcoming molecular genetics challenges improves outcomes and changes practice patterns.
Franasiak, J M, Scott, R T,
Trends Mol Med. 2014
doi:
|
|
Human embryonic aneuploidy.
Fragouli, E, Wells, D,
Encyclopedia of Life Sciences. 2014
doi:
|
|
Improved sensitivity to detect recombination using qPCR for Dyskeratosis Congenita PGD.
Gueye, N, Jalas, C, Tao, X, Taylor, D, Scott, R T, Treff, NR,
J Assist Reprod Genet. 2014
doi:
|
|
Increasing the probability of selecting chromosomally normal embryos by time-lapse morphokinetic analysis.
Basile, N, Bronet, F, Nogales, MC, Martinez, E, Ariza, M, Agudo, D, Florensa, M, Riqueros, M, Meseguer, M, Riqueros, M,
Fertil Steril. 2014
doi:
|
|
Live birth after PGD with confirmation by a comprehensive approach (karyomapping) for simultaneous detection of monogenic and chromosomal disorders.
Natesan, SA, Handyside, AH, Thornhill, AR, Ottolini, CS, Sage, K, Summers, MC, Konstantinidis, M, Wells, D, Griffin, DK,
RBM Online. 2014
doi:
|
|
Next-generation sequencing: the dawn of a new era for preimplantation genetic diagnostics.
Wells, D,
Fertil Steril. 2014
doi:
|
|
Obstetrical and neonatal outcomes from the BEST Trial: Single embryo transfer with aneuploidy screening improves outcomes after in vitro fertilization without compromising delivery rates.
Forman, EJ, Hong, KH, Franasiak, J M, Scott, R T,
Am J Obstet Gynecol. 2014
doi:
|
|
Polar body based aneuploidy screening is poorly predictive of embryo ploidy and reproductive potential.
Salvaggio, C, Forman, E, Garnsey, H, Treff, N, Scott, R T, Gueye, I,
J Assist Reprod Genet. 2014
doi:
|
|
Role of statins in PCOS management
Ortega, I, Duleba, AJ,
2014
doi:
|
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Simultaneous assessment of aneuploidy, polymorphisms, and mitochondrial DNA content in human polar bodies and embryos with the use of a novel microarray platform.
Konstantinidis, M, Alfarawati, S, Hurd, D, Paolucci, M, Shovelton, J, Fragouli, E, Wells, D,
Fertil Steril. 2014
doi:
|
|
Telomere length and aneuploidy: clinical and biological insights into human preimplantation embryos.
Simpson, JL, Wells, D,
RBM Online. 2014
doi:
|
|
The ethical implications of preimplantation genetic diagnosis.
Gronowski, AM, Scott, R T, Caplan, AL, Nelson, LJ,
Clin Chem. 2014
doi:
|
|
The nature of aneuploidy with increasing age of the female partner: a review of 15,169 consecutive trophectoderm biopsies evaluated with comprehensive chromosomal screening.
Franasiak, J M, Forman, EJ, Hong, KH, Werner, M D, Upham, KM, Treff, NR,
Fertil Steril. 2014
doi:
|
|
Uniparental disomy in the human blastocyst is exceedingly rare.
Gueye, N, Devkota, B, Taylor, D, Pfundt, R, Scott, R T, Tref, N,
Fertil Steril. 2014
doi:
|
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Preimplantation genetic screening using fluorescence in situ hybridization in patients with repetitive implantation failure and advanced maternal age: two randomized trials
Rubio, C, Bellver, J, Rodrigo, L, Bosch, E, Mercader, A, Vidal, C, De los Santos, M J, Giles, J, Labarta, E, Domingo, J, Crespo, J, Remohi, J, Pellicer, A, Simon, C,
Fertil Steril. Apr. 2013
doi: 10.1016/j.fertnstert.2012.11.041
|
|
False positive rate of an arrayCGH platform for single-cell preimplantation genetic screening and subsequent clinical application on day-3
Mir, P, Rodrigo, L, Mercader, A, Buendia, P, Mateu, E, Milan-Sanchez, M, Peinado, V, Pellicer, A, Remohi, J, Simon, C, Rubio, C,
J Assist Reprod Genet. Jan. 2013
doi: 10.1007/s10815-012-9918-4
|
|
Additive effect of factors related to assisted conception on the reduction of maternal serum pregnancy-associated plasma protein A concentrations and the increased false-positive rates in first-trimester Down syndrome screening.
Bellver, J, Casanova, C, Garrido, N, Lara, C, Remohi, J, Pellicer, A, Serra, V,
Fertil Steril. 2013
doi:
|
|
Alterations in the gene expression of aneuploid oocytes and associated cumulus cells.
Wells, D,
Biology and Pathology of the Oocyte. 2013
doi:
|
|
Effects of simvastatin on retinoic acid system in primary human endometrial stromal cells and in a chimeric model of human endometriosis.
Sokalska, A, Anderson, M, Villanueva, JA, Ortega, I, Bruner-Tran, KL, Osteen, KV, Duleba, AJ,
J Clin Endocrinol Metab. 2013
doi:
|
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Embryos whose polar bodies contain isolated reciprocal chromosome aneuploidy are almost always euploid.
Forman, EJ, Treff, NR, Stevens, JM, Garnsey, HM, Katz-Jaffe, MG, Scott, R T, Schoolcraft, WB,
Hum Reprod. 2013
doi:
|
|
Evaluation of targeted next-generation sequencing based preimplantation genetic diagnosis of monogenic disease.
Treff, NR, Fedick, A, Tao, X, Devkota, B, Taylor, D, Scott, R T,
Fertil Steril. 2013
doi:
|
|
Four-hour quantitative real-time polymerase chain reaction– based comprehensive chromosome screening and accumulating evidence of accuracy, safety predictive values and clinical efficacy.
Treff, NR, Scott, R T,
Fertil Steril. 2013
doi:
|
|
High-density SNP arrays and next generation sequencing for pre-implantation genetic diagnosis.
Handyside, A, Wells, D,
Gamete and embryo assessment in assisted reproduction: emerging technologies. 2013
doi:
|
|
Incidental identification of balanced translocation carrier patients through comprehensive chromosome screening of IVF-derived blastocysts.
Treff, NR, Forman, EJ, Katz-Jaffe, MG, Schoolcraft, WB, Levy, B, Scott, R T,
J Assist Reprod Genet. 2013
doi:
|
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Metabolomic profiling of oocytes and embryos using spectroscopy: potential clinical use and pitfalls.
Sakkas, D, Seli, E,
2013
doi:
|
|
Next-generation sequencing for preimplantation genetic diagnosis. Letter to the Editor.
Treff, NR, Forman, EJ, Scott, R T,
Fertil Steril. 2013
doi:
|
|
Obstetric and neonatal outcomes from the BEST Trial: Single embryo transfer with aneuploidy screening improves outcomes after IVF without compromising delivery rates.
Forman, EJ, Hong, KH, Franasiak, J M, Scott, R T,
Am J Obstet Gynecol. 2013
doi:
|
|
Preimplantation genetic diagnosis.
Wells, D, Fragouli, E,
The Textbook of Clinical Embryology. 2013
doi:
|
|
Preimplantation genetic screening.
Wells, D,
The Textbook of Clinical Embryology. 2013
doi:
|
|
Questions about the accuracy of polar body analysis for preimplantation genetic screening.
Fragouli, E, Wells, D,
Hum Reprod. 2013
doi:
|
|
Selecting the optimal time to perform biopsy for preimplantation genetics
Scott, KL, Hong, KH, Scott, R T,
Fertil Steril. 2013
doi:
|
|
The origin and impact of embryonic aneuploidy.
Fragouli, E, Alfarawati, S, Spath, K, Jaroudi, S, Sarasa, J, Enciso, M, Wells, D,
Hum Genet. 2013
doi:
|
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Treatment of Luteal Phase Defects in Assisted Reproduction.
Muñoz, E, Taboas, E, Portela, S, Aguilar, J, Fernandez, I, Muñoz, L, Bosch, E,
Curr Drug Targets. 2013
doi:
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Sperm DNA fragmentation index does not correlate with the sperm or embryo aneuploidy rate in recurrent miscarriage or implantation failure patients
Bronet, F, Martinez, E, Gaytan, M, Linan, A, Cernuda, D, Ariza, M, Nogales, M, Pacheco, A, San Celestino, M, Garcia-Velasco, J A,
Hum Reprod. Jul. 2012
doi: 10.1093/humrep/des148
|
|
Chromosomal abnormalities in embryos from couples with a previous aneuploid miscarriage
Al-Asmar, N, Peinado, V, Vera, M, Remohi, J, Pellicer, A, Simon, C, Hassold, T, Rubio, C,
Fertil Steril. Jul. 2012
doi: 10.1016/j.fertnstert.2012.03.035
|
|
Empty follicle syndrome after GnRHa triggering versus hCG triggering in COS
Castillo, J C, Garcia-Velasco, J A, Humaidan, P,
J Assist Reprod Genet. Mar. 2012
doi: 10.1007/s10815-011-9704-8
|
|
Alteration of gene expression in human cumulus cells as a potential indicator of oocyte aneuploidy.
Fragouli, E, Wells, D, Iager, AE, Kayisli, UA, Patrizio, P,
Hum Reprod. 2012
doi:
|
|
Aneuploidy Screening for Embryo Selection.
Fragouli, E, Wells, D,
Semin Reprod Med. 2012
doi:
|
|
Blastocyst preimplantation genetic diagnosis of a mitochondrial DNA disorder.
Treff, NR, Tao, X, Campos, J, Su, J, Ferry, KM, Levy, B, Scott, R T,
Fertil Steril. 2012
doi:
|
|
Characteristics of chromosomal abnormalities diagnosed after spontaneous abortions in an infertile population.
Werner, M D, Reh, A, Grifo, J, Perle, MA,
J Assist Reprod Genet. 2012
doi:
|
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Characterization of two heterozygous mutations of the oocyte activation factor phospholipase C zeta (PLC?) from an infertile man by use of minisequencing of individual sperm and expression in somatic cells.
Kashir, J, Konstantinidis, M, Jones, C, Heindryckx, B, Sutter, P, De, Parrington, J, Wells, D, Coward, K,
Fertil Steril. 2012
doi:
|
|
Comprehensive chromosome screening and embryo selection: moving toward single euploid blastocyst transfer.
Forman, EJ, Hong, KH, Treff, NR, Scott, R T,
Semin Reprod Med. 2012
doi:
|
|
Comprehensive chromosome screening is highly predictive of the reproductive potential of human embryos: a prospective, blinded, nonselection study.
Scott, R T, Ferry, KM, Su, J, Tao, X, Scott, KL, Treff, NR,
Fertil Steril. 2012
doi:
|
|
Delivery of a chromosomally normal child from an oocyte with reciprocal aneuploid polar bodies.
Scott, R T, Treff, NR, Stevens, J, Forman, EJ, Hong, KH, Katz-Jaffe, MG, Schoolcraft, WB,
J Assist Reprod Genet. 2012
doi:
|
|
Development and validation of an accurate quantitative real-time polymerase chain reaction – based assay for human blastocyst comprehensive chromosomal aneuploidy screening. Seminal Contribution.
Treff, NR, Tao, X, Ferry, KM, Su, J, Taylor, D, Scott, R T,
Fertil Steril. 2012
doi:
|
|
Empty follicle syndrome after GnRHa triggering versus hCG triggering in COS.
Castillo, JC, Garcia-Velasco, J A, Humaidan, P,
J Assist Reprod Genet. 2012
doi:
|
|
Intra-age, intercenter, and intercycle differences in chromosome abnormalities in oocytes.
Munne, S, Held, KR, Magli, CM, Ata, B, Wells, D, Fragouli, E, Baukloh, V, Fischer, R, Gianaroli, L, Fischer, R,
Fertil Steril. 2012
doi:
|
|
Methods for comprehensive chromosome screening of oocytes and embryos: capabilities, limitations, and evidence of validity.
Scott, R T,
J Assist Reprod Genet. 2012
doi:
|
|
Preimplantation genetic diagnosis (PGD), preimplantation genetic screening (PGS) and the transfer of in vitro fertilized embryos.
Wells, D,
Brenner’s Online Encyclopedia of Genetics. 2012
doi:
|
|
Single embryo transfer with comprehensive chromosome screening results in improved ongoing pregnancy rates and decreased miscarriage rates.
Forman, EJ, Tao, X, Ferry, KM, Taylor, D, Treff, NR, Scott, R T,
Hum Reprod. 2012
doi:
|
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Successful Live Birth following Preimplantation Genetic Diagnosis for Phenylketonuria in Day 3 Embryos by Specific Mutation Analysis and Elective Single Embryo Transfer.
Lavery, S, Abdo, D, JIMD, Reports, Kotrotsou, M, Trew, G, Konstantinidis, M, Wells, D,
JIMD Reports. 2012
doi:
|
|
Transcriptomic analysis of follicular cells provides information on the chromosomal status and competence of unfertilized oocytes.
Fragouli, E, Wells, D,
Expert Rev Mol Diagn. 2012
doi:
|
|
Cumulative live-birth rates per total number of embryos needed to reach newborn in consecutive in vitro fertilization (IVF) cycles: a new approach to measuring the likelihood of IVF success
Garrido, N, Bellver, J, Remohi, J, Simon, C, Pellicer, A,
Fertil Steril. Jul. 2011
doi: 10.1016/j.fertnstert.2011.05.008
|
|
A maternally inherited autosomal point mutation in human phospholipase C zeta (PLC?) leads to male infertility.
Kashir, J, Konstantinidis, M, Jones, C, Lemmon, B, Lee, HC, Hamer, R, Heindryckx, B, Deane, CM, De, Sutter, P, Fissore, RA, Parrington, J, Wells, D, Coward, K, Deane, CM,
Hum Reprod. 2011
doi:
|
|
Aneuploidy in the Human Blastocyst
Fragouli, E, Wells, D,
Cytogenet Genome Res. 2011
doi:
|
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Chromosome Abnormalities in the Human Oocyte.
Fragouli, E, Wells, D, Delhanty, J,
Cytogenet Genome Res. 2011
doi:
|
|
Effect of sperm DNA fragmentation on pregnancy outcome depends on oocyte quality
Meseguer, M, Santiso, R, Garrido, N, Garcia-Herrero, S, Remohi, J, Fernandez, JL,
Fertil Steril. 2011
doi:
|
|
Fertility after age 45: From natural conception to assisted reproductive technology and beyond.
Forman, EJ, Treff, NR, Scott, R T,
Maturitas. 2011
doi:
|
|
First births after preimplantation genetic diagnosis of structural chromosome abnormalities using comparative genomic hybridization and microarray analysis.
Alfarawati, S, Fragouli, E, Colls, P, Wells, D,
Hum Reprod. 2011
doi:
|
|
SNP Microarray Based Concurrent Screening of 24 Chromosome Aneuploidy and Unbalanced Translocations in Preimplantation Human Embryos.
Treff, NR, Northrop, L, Kasabwala, K, Su, J, Levy, B, Scott, R T,
Fertil Steril. 2011
doi:
|
|
Telomere DNA deficiency is associated with development of human embryonic aneuploidy.
Treff, NR, Su, J, Taylor, D, Scott, R T,
PLoS Genet. 2011
doi:
|
|
The cytogenetics of polar bodies: insights into female meiosis and the diagnosis of aneuploidy.
Fragouli, E, Alfarawati, S, Goodall, N, Sanchez-Garcia, JF, Colls, P, Wells, D,
Mol Hum Reprod. 2011
doi:
|
|
Therapeutic treatments of mtDNA diseases at the earliest stages of human development.
Chiaratti, MR, Meirelles, FV, Wells, D, Poulton, J,
Mitochondrion. 2011
doi:
|
|
Validation of microarray comparative genomic hybridization for comprehensive chromosome analysis of embryos.
Gutierrez-Mateo, C, Colls, P, Sanchez-Garcia, J, Escudero, T, Prates, R, Ketterson, K, Wells, D, Munne, S,
Fertil Steril. 2011
doi:
|
|
Accurate single cell 24 chromosome aneuploidy screening using whole genome amplification and single nucleotide polymorphism microarrays.
Treff, NR, Su, J, Tao, X, Levy, B, Scott, R T,
Fertil Steril. 2010
doi:
|
|
Aneploidies in embryos and spermatozoa from patients with Y chromosome microdelections.
Mateu, E, Rodrigo, L, Martinez, MC, Peinedo, V, Delagado, A, MIr, P, Simon, C, Remohi, J,
RBM Online. 2010
doi:
|
|
Assessing the reproductive competence of individual embryos: a proposal for the validation of new "-omics" technologies.
Scott, R T, Treff, NR,
Fertil Steril. 2010
doi:
|
|
Cytogenetic analysis of human blastocysts with the use of FISH, CGH and aCGH: scientific data and technical evaluation.
Fragouli, E, Alfarawati, S, Daphnis, D, Goodall, N, Mania, A, Griffiths, T, Gordon, T, Wells, D,
Hum Reprod. 2010
doi:
|
|
Embryo aneuploidy and the role of morphological and genetic screening.
Wells, D,
RBM Online. 2010
doi:
|
|
GnRH agonist administration at the time of implantation does not improve pregnancy outcome in intrauterine insemination cycles: a randomized controlled tria
Bellver, J, E, Labarta, Bosch, E, Melo, MAB, Vidal, C, Remohi, J, Pellicer, A,
Fertil Steril. 2010
doi:
|
|
Impacto de un complejo de antioxidantes sobre la fragmentación del ADN espermático en varones infértiles
Balmori, C, Areces, C, Pacheco, A, San, Celestino, M, Garcia-Velasco, J A,
Rev Int Androl. 2010
doi:
|
|
Improved detection of aneuploid blastocysts using a new 12-chromosome FISH test.
Munne, S, Fragouli, E, Colls, P, Katz-Jaffe, MG, Schoolcraft, WB, Wells, D,
RBM Online. 2010
doi:
|
|
Improving FISH diagnosis for preimplantation genetic aneploidy screening
Mir, P, Rodrigo, L, Mateu, E, Milan, M, Mercader, A, Buendia, P, Delgado, A, Pellicer, A, Remohi, J, Rubio, C,
Hum Reprod. 2010
doi:
|
|
Microarrays and CGH for PGD of chromosome abnormalities and gene defects.
Munne, S, Harton, G, Held, K, Wells, D,
Journal of Reproductive Medicine and Endocrinology. 2010
doi:
|
|
Robust embryo identification using polar body single nucleotide polymorphism microarray based DNA fingerprinting.
Treff, NR, Su, J, Kasabwala, N, Tao, X, Miller, KA, Scott, R T,
Fertil Steril. 2010
doi:
|
|
Severe Refractory Hidradenitis Suppurativa in HIV-Positive Patient Successfully Treated with Infliximab.
Alecsandru, D, Padilla, B, Aviles, Izquierdo, JA, Fernandez-, Cruz, E, Sanchez-Ramon, S,
Archives of Dermatology. 2010
doi:
|
|
Single Cell Whole Genome Amplification Technique Impacts the Accuracy of SNP Microarray Based Genotyping and Copy Number Analyses.
Treff, NR, Su, J, Tao, X, Northrop, L, Scott, R T,
Mol Hum Reprod. 2010
doi:
|
|
SNP microarray based 24 chromosome aneuploidy screening demonstrates that cleavage stage FISH poorly predicts aneuploidy in embryos that develop to morphologically normal blastocysts.
Northrop, L, Treff, NR, Levy, B, Scott, R T,
Mol Hum Reprod. 2010
doi:
|
|
SNP microarray based 24 chromosome aneuploidy screening is significantly more consistent than FISH.
Treff, NR, Levy, B, Su, J, Northrop, L, Tao, X, Scott, R T,
Mol Hum Reprod. 2010
doi:
|
|
Surgical management of tubal disease and infertility
Coughlan, C, TC, Li,
Obstetrics. 2010
doi:
|
|
Technology requirements for preimplantation genetic diagnosis to improve assisted reproduction outcomes.
Munne, S, Wells, D, Cohen, J,
Fertil Steril. 2010
doi:
|
|
Transcriptomic profiling of human oocytes: association of meiotic aneuploidy and altered oocyte gene expression.
Fragouli, E, Bianchi, V, Patrizio, P, Obradors, A, Huang, Z, Borini, A, Delhanty, J, Wells, D,
Mol Hum Reprod. 2010
doi:
|
|
Transmission of Mitochondrial DNA Diseases and Ways to Prevent Them.
Poulton, J, Chiaratti, MR, Meirelles, FV, Kennedy, S, Wells, D, Holt, IJ,
PLoS Genet. 2010
doi:
|
|
Y chromosome microdeletions, sperm DNA fragmentation and sperm oxidative stress as causes of recurrent spontaneous abortion of unknown etiology.
Bellver, J, Meseguer, M, Muriel, L, Garcia-Herrero, S, Barreto, MAM, Garda, AL, Remohi, J, Pellicer, A, Garrido, N, Pellicer, A,
Hum Reprod. 2010
doi:
|
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Comparative genomic hybridization of oocytes and first polar bodies from young donors.
Fragouli, E, Escalona, A, Gutierrez-Mateo, C, Tormasi, S, Alfarawati, S, Sepulveda, S, Wells, D, Munne, S,
RBM Online. 2009
doi:
|
|
Soluble vascular endothelial-cadherin levels correlate with clinical and biological aspects of severe ovarian hyperstimulation syndrome
Villasante, A, Pacheco, A, Pau, E, Ruiz, A, Pellicer, A, Garcia-Velasco, J A,
Hum Reprod. Mar. 2008
doi: 10.1093/humrep/dem429
|
|
Birth of a healthy boy after a double factor PGD in a couple carrying a genetic disease and at risk for aneuploidy.
Obradors, A, Fernandez, E, Oliver-Bonet, M, Rius, M, de, la, Fuente, A, Wells, D, Benet, J, Navarro, J,
Hum Reprod. 2008
doi:
|
|
Evaluation of embryo quality by Metabolomics: A new strategy to aid single embryo transfer.
Sakkas, D, Morita, H, Yamashita, N, Kato, LO, Botros, L, Roos, P, Seli, E,
J Mammal Ova Res. 2008
doi:
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Técnica de B-Lynch en el control de la hemorragia posparto Progresos de Obstetricia
Blanco, M, Gomez, E, Manosalvas, P, Izquierdo, A, Puente, J M, Hernandez, Garcia, JM,
Ginecología. 2008
doi:
|
|
Sperm selection by swim-up in terms of deoxyribonucleic acid fragmentation as measured by the sperm chromatin dispersion test is altered in heavy smokers
Viloria, T, Garrido, N, Fernandez, J L, Remohi, J, Pellicer, A, Meseguer, M,
Fertil Steril. Aug. 2007
doi: 10.1016/j.fertnstert.2006.11.135
|
|
Artículo de revisión "Diagnóstico por imagen”
Puente, J M, Grañeras, A, Requena, A,
Cuadernos de Medicina Reproductiva. 2007
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Single cell diagnosis using comparative genomic hybridization after preliminary DNA amplification still needs more tweaking: too many miscalls.
Fragouli, E, Delhanty, JD, Wells, D,
Fertil Steril. 2007
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Heteroparental blastocyst production from microsurgically corrected tripronucleated human embryos
Escriba, M J, Martin, J, Rubio, C, Valbuena, D, Remohi, J, Pellicer, A, Simon, C,
Fertil Steril. Dec. 2006
doi: 10.1016/j.fertnstert.2006.04.047
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A successful strategy for Preimplantation Genetic Diagnosis of betathalassemia and simultaneous detection of Down's syndrome using multiplex fluorescent PCR.
Piyamongkol, W, Vutyavanich, T, Piyamongkol, S, Wells, D, Kunaviktikul, C, Tongsong, T, Chaovisitsaree, S, Saetung, R, Sanguansermsri, T, Saetung, R,
J Med Assoc Thai. 2006
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Estudio comparativo de dos medios de cultivo HTF e ISM-1: implicaciones en el fenotipo embrionario y resultados clínicos.
Gimeno, L, Lopez, MA, Meseguer, M, Santos, JM, Pellicer, A, Remohi, J, Santos, MJ,
Revista Iberoamericana de Fertilidad y Reproducción Humana. 2006
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Heteroparental blastocyst production from microsurgically corrected tripronucleated human embryos.
Escriba, M J, Martin, J, Rubio, C, Valbuena, D, Remohi, J, Pellicer, A, Simon, C,
Fertil Steril. 2006
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J.Ultrastructure of preimplantation genetic diagnosis-derived human blastocysts grown in a coculture system after vitrification.
Escriba, M J, Escobedo-Lucea, C, Mercader, A, De, Los, Santos, MJ, Pellicer, A, Remohi, J,
Fertil Steril. 2006
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Prenatal management of placental chorioangioma: value of the middle cerebral artery peak systolic velocity.
Escribano, D, Galindo, A, Arbues, J, Puente, J M, De, la, Fuente, P,
Fetal Diagn Ther. 2006
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Use of Real-Time Polymerase Chain Reaction to Measure Gene Expression in Single Cells.
Wells, D,
Single Cell Diagnostics: Methods and Protocols. 2006
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The singleton, term gestation, and live birth rate per cycle initiated: a 1-year experience in in vitro fertilization cycles with native and donated oocytes
Bellver, J, Albert, C, Soares, S R, Alvarez, C, Pellicer, A,
Fertil Steril. May. 2005
doi: 10.1016/j.fertnstert.2004.11.047
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Association of abnormal morphology and altered gene expression in human preimplantation embryos.
Wells, D, Bermúdez, MG, Steuerwald, N, Malter, HE, Thornhill, AR, Cohen, J,
Fertil Steril. 2005
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Etiologia, diagnostico y manejo del hidrops fetal: revision de 140 casos
Arbues, J, Galindo, A, Puente, J M, Grañeras, A, De, la, Fuente, P,
Prog Obstet Ginecol. 2005
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Expression of genes regulating chromosome segregation, the cell cycle and apoptosis during human preimplantation development.
Wells, D, Bermudez, MG, Steuerwald, N, Thornhill, AR, Walker, DL, Malter, H, Delhanty, JDA, Cohen, J,
Hum Reprod. 2005
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Isolated unilateral pulmonary agenesis. Early prenatal diagnosis and long-term follow up.
Arbues, J, Galindo, A, Rasero, M, Orbea, C, Puente, J M, De, la, Fuente, P,
J Ultrasound Med. 2005
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Near Speed-of-Light On-Chip Interconnects Using Pulsed Current-Mode Signaling.
Jose, AP, Patounakis, G, Shepard, KL,
2005 Symposium on VLSI Circuits. 2005
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Advances in preimplantation genetic diagnosis.
Wells, D,
Eur J Obstet Gynecol Reprod Biol. 2004
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Reliability of comparative genomic hybridization to detect chromosome abnormalities in first polar bodies and metaphase II oocytes.
Gutierrez-Mateo, C, Wells, D, Benet, J, Sanchez-Garcia, JF, Bermúdez, MG, Belil, I, Egozcue, J, Munne, S, Navarro, J, Munne, S,
Hum Reprod. 2004
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Detailed investigation of factors influencing amplification efficiency and allele drop-out in single cell PCR: implications for preimplantation genetic diagnosis.
Piyamongkol, W, Bermudez, MG, Harper, JC, Wells, D,
Mol Hum Reprod. 2003
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Rabbit and pig ear skin sample cryobanking: effects of storage time and temperature of the whole ear extirpated immediately after death.
Silvestre, MA, Saeed, AM, Cervera, RP, Escriba, M J, Garcia-Ximenez, F,
Theriogenology. 2003
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Single-cell sequencing and mini-sequencing for preimplantation genetic diagnosis.
Bermudez, MG, Piyamongkol, W, Tomaz, S, Dudman, E, Sherlock, JK, Wells, D,
Prenat Diagn. 2003
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The "vanishing embryo" phenomenon in an oocyte donation programme
Rodriguez-Gonzalez, M, Serra, V, Garcia-Velasco, J A, Pellicer, A, Remohi, J,
Hum Reprod. Mar. 2002
doi: 10.1093/humrep/17.3.798
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First clinical application of comparative genomic hybridization and polar body testing for preimplantation genetic diagnosis of aneuploidy.
Wells, D, Escudero, T, Levy, B, Hirschhorn, K, Delhanty, JDA, Munne, S,
Fertil Steril. 2002
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New techniques on embryo manipulation.
Escriba, M J, Valbuena, D, Remohi, J, Pellicer, A, Simon, C,
J Reprod Immunol. 2002
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Preimplantation genetic diagnosis for single gene disorders: experience with five single gene disorders.
Harper, JC, Wells, D, Piyamongkol, W, Abou-Sleiman, P, Apessos, A, Ioulianos, A, Davis, M, Doshi, A, Serhal, P, Ranieri, M, Rodeck, C, Delhanty, JDA,
Prenat Diagn. 2002
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Preimplantation genetic diagnosis: an alternative to prenatal diagnosis.
Delhanty, JDA, Wells, D,
Expert Rev Mol Diagn. 2002
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The "vanishing embryo" phenomenon in an oocyte donation programme.
Rodriguez-Gonzalez, M, Serra, V, Garcia-Velasco, J A, Pellicer, A, Remohi, J,
Fertil Steril. 2002
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Towards a comprehensive analysis of chromosomes and DNA sequences in human embryos.
Wells, D,
Advances in Infertility Treatment (Monduzzi Editore. 2002
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Viable offspring derived from cryopreserved haploid rabbit parthenotes
Garcia-Ximenez, F, Escriba, M J,
Theriogenology. 2002
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Vitrification and rapid freezing of rabbit fetal tissues and skin samples from rabbits and pigs.
Silvestre, MA, Saeed, AM, Escriba, M J, Garcia-Ximenez, F,
Theriogenology. 2002
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A successful strategy for preimplantation genetic diagnosis of myotonic dystrophy using multiplex fluorescent PCR.
Piyamongkol, W, Harper, JC, Sherlock, JK, Doshi, A, Serhal, PF, Delhanty, JDA, Wells, D,
Prenat Diagn. 2001
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Acrocentric chromosome disomy is increased in spermatozoa from fathers of Turner syndrome patients
Soares, S R, Vidal, F, Bosch, M, Martinez-Pasarell, O, Nogues, C, Egozcue, J, Templado, C,
Hum Genet. 2001
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Comparison of the effect of two different handling media on rabbit zygote developmental ability
Escriba, M J, Silvestre, MA, Saeed, AM, Garcia-Ximenez, F,
Reprod Nutr Dev. 2001
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Future developments in preimplantation genetic diagnosis.
Harper, J, Wells, D,
Preimplantation Genetic Diagnosis. 2001
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Genetic alterations in gastric cancers from British patients.
Sud, R, Wells, D, Talbot, IC, Delhanty, JDA,
Cancer Genet Cytogenet. 2001
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Numerical chromosome abnormalities in the spermatozoa of the fathers of children with trisomy 21 of paternal origin: generalised tendency to meiotic non-disjunction.
Soares, S R, Templado, C, Blanco, J, Egozcue, J, Vidal, F,
Hum Genet. 2001
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PGD protocols using multiplex fluorescent PCR.
Piyamongkol, W, Harper, CJ, Delhanty, JDA, Wells, D,
RBM Online. 2001
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Preimplantation genetic diagnosis: applications for molecular medicine.
Wells, D, Delhanty, JDA,
Trends Mol Med. 2001
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Preimplantation genetic diagnostic protocols for alpha- and beta-thalassaemias using multiplex fluorescent PCR.
Piyamongkol, W, Harper, JC, Delhanty, JDA, Wells, D,
Prenat Diagn. 2001
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A successful strategy for preimplantation diagnosis of medium-chain acyl-CoA dehydrogenase (MCAD) deficiency.
Ioulianos, A, Wells, D, Harper, JC, Delhanty, JDA,
Prenat Diagn. 2000
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Comparative Genomic Hybridization Reveals Extensive Variation Among Different MCF-7 Cell Stocks.
Jones, C, Payne, J, Wells, D, Delhanty, JDA, Lakhani, SR, Kortenkamp, A,
Cancer Genet Cytogenet. 2000
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Comprehensive chromosomal analysis of human preimplantation embryos using whole genome amplification and single cell comparative genomic hybridization.
Wells, D, Delhanty, JDA,
Mol Hum Reprod. 2000
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Deletion and duplication of the adenomatous polyposis coli gene resulting from an interchromosomal insertion involving 5 (q22q23.3) in the father.
Hastings, RJ, Svennevik, EC, Setterfield, B, Wells, D, Delhanty, JDA, Mackinnon, H,
J Med Genet. 2000
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Vitrification and rapid-freezing of cumulus cells from rabbits and pigs.
Saeed, AM, Escriba, M J, Silvestre, MA, Garcia-Ximenez, F,
Theriogenology. 2000
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Positive outcome after preimplantation diagnosis of aneuploidy in human embryos.
Munne, S, Magli, C, Cohen, J, Morton, P, Sadowy, S, Gianaroli, L, Tucker, M, Marquez, C, Sable, D, Ferraretti, AP, Massey, JB, Scott, R T,
Hum Reprod. 1999
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Preimplantation genetic diagnosis of cancer: familial adenomatous polyposis coli (FAPC).
Ao, A, Wells, D, Handyside, AH, Winston, RML, Delhanty, JDA,
J Assist Reprod Genet. 1998
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Strategies for preimplantation genetic diagnosis of single gene disorders by DNA amplification.
Wells, D, Sherlock, JK,
Prenat Diagn. 1998
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Detection of haemoglobinopathies and chromosome aneuploidy from minute DNA samples using multiplex PCR.
Sherlock, J, Cirigliano, V, Petrou, M, Wells, D, Adinolfi, M,
Infertility and Assisted Reproductive Technology - From Research to Therapy. 1997
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Genetic diagnosis before implantation.
Delhanty, JDA, Wells, D, Harper, JC,
BMJ. 1997
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APC gene mutation and DNA microsatellite instability in pancreatic cancers of UK origin.
See, CG, Sud, R, Wells, D, Bowles, L, Ding, S, Habib, N, Delhanty, JDA,
GI Cancer 2. 1996
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Preimplantation genetic diagnosis of beta-thalassaemia.
El-Hashemite, N, Wells, D, Delhanty, JDA,
Lancet. 1996
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Correlation of loss of heterozygosity with cytogenetic analysis using g-banding and fluorescence in situ hybridization in aneuploid cultures from two human testicular germ-cell tumors.
Al-Jehani, RMA, Wells, D, Fox, M, Parrington, JM,
Cancer Genet Cytogenet. 1995
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Rapid detection of rare variants and common polymorphisms in the APC gene by PCR-SSCP for presymptomatic diagnosis and showing allele loss.
Gayther, SA, Sud, R, Wells, D, Tsioupra, K, Delhanty, JD,
J Med Genet. 1995
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