Roberta Maggiulli

Biography

Dr. Roberta Maggiulli is a senior clinical embryologist and Lab operation Director of GENERA IVF laboratories in Italy. She obtained her BSc and MSc degrees from the University of Parma.

She obtained her BSc and MSc degrees from the University of Parma in “Biotechnology” and “Medical Biotechnology” and her PhD magna cum laude in “Clinical Biochemistry”. After a four-year internship as clinical embryologist at the University of Parma, she was employed as a Research Staff Associate at the Center for Reproductive Medicine and Infertility (CRMI) of the Weill Cornell Medical College in New York. Afterwards, she joined the Genera centers where she worked as Lab supervisor for 12 years, contributing to the validation and standardization of laboratory practices. She is author or coauthor of several articles in peer-reviewed journals, book chapters and several abstracts in national and international meetings.

Education and Training

B.Sc. in “Biotechnology”	University of Parma, Italy (2002)
M.Sc. in “Medical Biotechnologies”	University of Parma, Italy (2004)
School of Specialization in Clinical Biochemistry	University of Parma, Italy (2009)
II Level Master in “Reproductive biology and biotechnology: from research to the clinic application”	University of Pavia (2022)

Honors and recognition

Certification as “Senior Clinical Embryologist” by the European Society of Human Reproduction and Embryology (ESHRE)	2010
Member of the scientific committee of SIERR (Italian Society of Embryology, Reproduction and Research)
Member of Editorial Board of RBMO

Publications

Cryostorage management of reproductive cells and tissues in ART: status, needs, opportunities, and potential new challenges
Canosa S, Maggiulli R, Cimadomo D, Innocenti F, Fabozzi G, Gennarelli G, Revelli A, Bongioanni F, Vaiarelli A, Ubaldi FM, Rienzi L, Palmer GA, Nijs M

Reproductive BioMedicine Online Available online 22 June 202 In press. 2023 doi:

Humidified atmosphere in a time-lapse embryo culture system does not improve ongoing pregnancy rate: a retrospective propensity score model study derived from 496 first ICSI cycles.
Bartolacci A, Borini A, Cimadomo D, Fabozzi G, Maggiulli R, Lagalla C, Pignataro D, dell'Aquila M, Parodi F, Patria G, Zacà C, Ubaldi FM, Rienzi L, Coticchio G

J Assist Reprod Genet. 2023 May 3. doi: 10.1007/s10815-023-02818-8. Online ahead of print. . 2023 doi:

Towards Automation in IVF: Pre-Clinical Validation of a Deep Learning-Based Embryo Grading System during PGT-A Cycles.
Cimadomo D, Chiappetta V, Innocenti F, Saturno G, Taggi M, Marconetto A, Casciani V, Albricci L, Maggiulli R, Coticchio G, Ahlström A, Berntsen J, Larman M, Borini A, Vaiarelli A, Ubaldi FM, Rienzi L

J Clin Med. 2023 Feb 23;12(5):1806. doi: 10.3390/jcm12051806.. 2023 doi:

Discard or not discard, that is the question: an international survey across 117 embryologists on the clinical management of borderline quality blastocysts.
Chiappetta V, Innocenti F, Coticchio G, Ahlström A, Albricci L, Badajoz V, Hebles M, Gallardo M, Benini F, Canosa S, Kumpošt J, Milton K, Montanino Oliva D, Maggiulli R, Rienzi L, Cimadomo D

Hum Reprod. 2023 Aug 30:dead174. doi: 10.1093/humrep/dead174. Online ahead of print.. 2023 doi:

Clinical, obstetric and perinatal outcomes after vitrified-warmed euploid blastocyst transfer are independent of cryo-storage duration.
Cimadomo D, Fabozzi G, Dovere L, Maggiulli R, Albricci L, Innocenti F, Soscia D, Giancani A, Vaiarelli A, Guido M, Ubaldi FM, Rienzi L

Reprod Biomed Online. 2022 Feb;44(2):221-227. doi: 10.1016/j.rbmo.2021.09.027. Epub 2021 Oct 8.. 2022 doi:

How slow is too slow? A comprehensive portrait of Day 7 blastocysts and their clinical value standardized through artificial intelligence.
Cimadomo D, Soscia D, Casciani V, Innocenti F, Trio S, Chiappetta V, Albricci L, Maggiulli R, Erlich I, Ben-Meir A, Har-Vardi I, Vaiarelli A, Ubaldi FM, Rienzi L

Hum Reprod. 2022 May 30;37(6):1134-1147. doi: 10.1093/humrep/deac080. . 2022 doi:

Inter-centre reliability in embryo grading across several IVF clinics is limited: implications for embryo selection.
Cimadomo D, Sosa Fernandez L, Soscia D, Fabozzi G, Benini F, Cesana A, Dal Canto MB, Maggiulli R, Muzzì S, Scarica C, Rienzi L, De Santis L

Reprod Biomed Online. 2022 Jan;44(1):39-48. doi: 10.1016/j.rbmo.2021.09.022. Epub 2021 Oct 6. . 2022 doi:

The effect of extended cryo-storage following vitrification on embryo competence: a systematic review and meta-analysis.
Canosa S, Cimadomo D, Conforti A, Maggiulli R, Giancani A, Tallarita A, Golia F, Fabozzi G, Vaiarelli A, Gennarelli G, Revelli A, Bongioanni F, Alviggi C, Ubaldi FM, Rienzi L, SIERR

J Assist Reprod Genet. 2022 Apr;39(4):873-882. doi: 10.1007/s10815-022-02405-3. Epub 2022 Feb 4.. 2022 doi:

Blastulation rates of sibling oocytes in two IVF culture media: an evidence-based workflow to implement newly commercialized products.
Fabozzi G, Albricci L, Cimadomo D, Amendola MG, Sanges F, Maggiulli R, Ubaldi FM, Rienzi L

Reprod Biomed Online. 2021 Feb;42(2):311-322. doi: 10.1016/j.rbmo.2020.10.017. Epub 2020 Nov 4.. 2021 doi:

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives.
Maggiulli R, Vaiarelli A, Cimadomo D, Giancani A, Tacconi L, Fabozzi G, Ubaldi FM, Rienzi L

J Vis Exp. 2021 Sep 16;(175). doi: 10.3791/61963.. 2021 doi:

Leave the past behind: women's reproductive history shows no association with blastocysts' euploidy and limited association with live birth rates after euploid embryo transfers.
Cimadomo D, Capalbo A, Dovere L, Tacconi L, Soscia D, Giancani A, Scepi E, Maggiulli R, Vaiarelli A, Rienzi L, Ubaldi FM

Hum Reprod. 2021 Mar 18;36(4):929-940. doi: 10.1093/humrep/deab014.. 2021 doi:

Maternal body mass index associates with blastocyst euploidy and live birth rates: the tip of an iceberg?
Fabozzi G, Cimadomo D, Allori M, Vaiarelli A, Colamaria S, Argento C, Amendola MG, Innocenti F, Soscia D, Maggiulli R, Mazzilli R, Ubaldi N, Iussig B, Marchetti M, Rienzi L, Ubaldi FM

Reprod Biomed Online. 2021 Oct;43(4):645-654. doi: 10.1016/j.rbmo.2021.07.006. Epub 2021 Jul 22.. 2021 doi:

The Impact of Unbalanced Maternal Nutritional Intakes on Oocyte Mitochondrial Activity: Implications for Reproductive Function.
Fabozzi G, Iussig B, Cimadomo D, Vaiarelli A, Maggiulli R, Ubaldi N, Ubaldi FM, Rienzi L

Antioxidants (Basel). 2021 Jan 11;10(1):91. doi: 10.3390/antiox10010091.. 2021 doi:

Assessment and management of the risk of SARS-CoV-2 infection in an IVF laboratory.
Maggiulli R, Giancani A, Fabozzi G, Dovere L, Tacconi L, Amendola MG, Cimadomo D, Ubaldi FM, Rienzi L

Reprod Biomed Online. 2020 Sep;41(3):385-394. doi: 10.1016/j.rbmo.2020.06.017. Epub 2020 Jun 27.. 2020 doi:

Corrigendum. Definition of a clinical strategy to enhance the efficacy, efficiency and safety of egg donation cycles with imported vitrified oocytes.
Rienzi L, Cimadomo D, Maggiulli R, Vaiarelli A, Dusi L, Buffo L, Amendola MG, Colamaria S, Giuliani M, Bruno G, Stoppa M, Ubaldi FM

Hum Reprod. 2020 Aug 1;35(8):1944. doi: 10.1093/humrep/deaa145.. 2020 doi:

Definition of a clinical strategy to enhance the efficacy, efficiency and safety of egg donation cycles with imported vitrified oocytes.
Rienzi L, Cimadomo D, Maggiulli R, Vaiarelli A, Dusi L, Buffo L, Amendola MG, Colamaria S, Giuliani M, Bruno G, Stoppa M, Ubaldi FM

Hum Reprod. 2020 Apr 28;35(4):785-795. doi: 10.1093/humrep/deaa009.. 2020 doi:

The effect of ICSI-related procedural timings and operators on the outcome.
Maggiulli R, Cimadomo D, Fabozzi G, Papini L, Dovere L, Ubaldi FM, Rienzi L

Hum Reprod. 2020 Jan 1;35(1):32-43. doi: 10.1093/humrep/dez234.. 2020 doi:

Which key performance indicators are most effective in evaluating and managing an in vitro fertilization laboratory?
Fabozzi G, Cimadomo D, Maggiulli R, Vaiarelli A, Ubaldi FM, Rienzi L

Fertil Steril. 2020 Jul;114(1):9-15. doi: 10.1016/j.fertnstert.2020.04.054. Epub 2020 Jun 9. . 2020 doi:

A brief history of oocyte cryopreservation: Arguments and facts.
Iussig B, Maggiulli R, Fabozzi G, Bertelle S, Vaiarelli A, Cimadomo D, Ubaldi FM, Rienzi L

Acta Obstet Gynecol Scand. 2019 May;98(5):550-558. doi: 10.1111/aogs.13569. Epub 2019 Mar 25.. 2019 doi:

Advanced Maternal Age in IVF: Still a Challenge? The Present and the Future of Its Treatment.
Ubaldi FM, Cimadomo D, Vaiarelli A, Fabozzi G, Venturella R, Maggiulli R, Mazzilli R, Ferrero S, Palagiano A, Rienzi L

Front Endocrinol (Lausanne). 2019 Feb 20;10:94. doi: 10.3389/fendo.2019.00094. eCollection 2019.. 2019 doi:

Human Blastocyst Biopsy and Vitrification.
Maggiulli R, Giancani A, Cimadomo D, Ubaldi FM, Rienzi L

J Vis Exp. 2019 Jul 26;(149). doi: 10.3791/59625.. 2019 doi:

Looking past the appearance: a comprehensive description of the clinical contribution of poor-quality blastocysts to increase live birth rates during cycles with aneuploidy testing.
Cimadomo D, Soscia D, Vaiarelli A, Maggiulli R, Capalbo A, Ubaldi FM, Rienzi L

Hum Reprod. 2019 Jul 8;34(7):1206-1214. doi: 10.1093/humrep/dez078.. 2019 doi:

Associations of blastocyst features, trophectoderm biopsy and other laboratory practice with post-warming behavior and implantation.
Cimadomo D, Capalbo A, Levi-Setti PE, Soscia D, Orlando G, Albani E, Parini V, Stoppa M, Dovere L, Tacconi L, Ievoli E, Maggiulli R, Ubaldi FM, Rienzi L

Hum Reprod. 2018 Nov 1;33(11):1992-2001. doi: 10.1093/humrep/dey291.. 2018 doi:

Continuous embryo culture elicits higher blastulation but similar cumulative delivery rates than sequential: a large prospective study.
Cimadomo D, Scarica C, Maggiulli R, Orlando G, Soscia D, Albricci L, Romano S, Sanges F, Ubaldi FM, Rienzi L

J Assist Reprod Genet. 2018 Jul;35(7):1329-1338. doi: 10.1007/s10815-018-1195-4. Epub 2018 May 3.. 2018 doi:

Abnormally fertilized oocytes can result in healthy live births: improved genetic technologies for preimplantation genetic testing can be used to rescue viable embryos in in vitro fertilization cycles.
Capalbo A, Treff N, Cimadomo D, Tao X, Ferrero S, Vaiarelli A, Colamaria S, Maggiulli R, Orlando G, Scarica C, Scott R, Ubaldi FM, Rienzi L

Fertil Steril. 2017 Dec;108(6):1007-1015.e3. doi: 10.1016/j.fertnstert.2017.08.004. Epub 2017 Sep 15.. 2017 doi:

Oocyte, embryo and blastocyst cryopreservation in ART: systematic review and meta-analysis comparing slow-freezing versus vitrification to produce evidence for the development of global guidance.
Rienzi L, Gracia C, Maggiulli R, LaBarbera AR, Kaser DJ, Ubaldi FM, Vanderpoel S, Racowsky C

Hum Reprod Update. 2017 Mar 1;23(2):139-155. doi: 10.1093/humupd/dmw038. . 2017 doi:

Consistent and reproducible outcomes of blastocyst biopsy and aneuploidy screening across different biopsy practitioners: a multicentre study involving 2586 embryo biopsies.
Capalbo A, Ubaldi FM, Cimadomo D, Maggiulli R, Patassini C, Dusi L, Sanges F, Buffo L, Venturella R, Rienzi L

Hum Reprod. 2016 Jan;31(1):199-208. doi: 10.1093/humrep/dev294. Epub 2015 Dec 4.. 2016 doi:

Electronic witness system in IVF-patients perspective.
Forte M, Faustini F, Maggiulli R, Scarica C, Romano S, Ottolini C, Farcomeni A, Palagiano A, Capalbo A, Ubaldi FM, Rienzi L

J Assist Reprod Genet. 2016 Sep;33(9):1215-22. doi: 10.1007/s10815-016-0759-4. Epub 2016 Jul 7.. 2016 doi:

Failure mode and effects analysis of witnessing protocols for ensuring traceability during PGD/PGS cycles.
Cimadomo D, Ubaldi FM, Capalbo A, Maggiulli R, Scarica C, Romano S, Poggiana C, Zuccarello D, Giancani A, Vaiarelli A, Rienzi L

Reprod Biomed Online. 2016 Sep;33(3):360-9. doi: 10.1016/j.rbmo.2016.06.002. Epub 2016 Jun 23.. 2016 doi:

Failure mode and effects analysis of witnessing protocols for ensuring traceability during IVF.
Rienzi L, Bariani F, Dalla Zorza M, Romano S, Scarica C, Maggiulli R, Nanni Costa A, Ubaldi FM

Reprod Biomed Online. 2015 Oct;31(4):516-22. doi: 10.1016/j.rbmo.2015.06.018. Epub 2015 Jul 7.. 2015 doi:

No evidence of association between blastocyst aneuploidy and morphokinetic assessment in a selected population of poor-prognosis patients: a longitudinal cohort study.
Rienzi L, Capalbo A, Stoppa M, Romano S, Maggiulli R, Albricci L, Scarica C, Farcomeni A, Vajta G, Ubaldi FM

Reprod Biomed Online. 2015 Jan;30(1):57-66. doi: 10.1016/j.rbmo.2014.09.012. Epub 2014 Oct 5.. 2015 doi:

Reduction of multiple pregnancies in the advanced maternal age population after implementation of an elective single embryo transfer policy coupled with enhanced embryo selection: pre- and post-intervention study.
Ubaldi FM, Capalbo A, Colamaria S, Ferrero S, Maggiulli R, Vajta G, Sapienza F, Cimadomo D, Giuliani M, Gravotta E, Vaiarelli A, Rienzi L

Hum Reprod. 2015 Sep;30(9):2097-106. doi: 10.1093/humrep/dev159. Epub 2015 Jul 5.. 2015 doi:

Correlation between standard blastocyst morphology, euploidy and implantation: an observational study in two centers involving 956 screened blastocysts.
Capalbo A, Rienzi L, Cimadomo D, Maggiulli R, Elliott T, Wright G, Nagy ZP, Ubaldi FM

Hum Reprod. 2014 Jun;29(6):1173-81. doi: 10.1093/humrep/deu033. Epub 2014 Feb 26.. 2014 doi:

The worldwide frozen embryo reservoir: methodologies to achieve optimal results.
Capalbo A, Rienzi L, Buccheri M, Maggiulli R, Sapienza F, Romano S, Colamaria S, Iussig B, Giuliani M, Palagiano A, Ubaldi F

Ann N Y Acad Sci. 2011 Mar;1221:32-9. doi: 10.1111/j.1749-6632.2010.05931.x.. 2011 doi:

Embryo development of fresh 'versus' vitrified metaphase II oocytes after ICSI: a prospective randomized sibling-oocyte study.
Rienzi L, Romano S, Albricci L, Maggiulli R, Capalbo A, Baroni E, Colamaria S, Sapienza F, Ubaldi F

Hum Reprod. 2010 Jan;25(1):66-73. doi: 10.1093/humrep/dep346. Epub 2009 Oct 27.. 2010 doi:

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Biography

Education and Training

Honors and recognition

Publications