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The first mitotic division: a perilous bridge connecting the zygote and the early embryo.
Coticchio G, Cimadomo D, Cermisoni GC, Rienzi L, Papaleo E, Ubaldi FM, Borini A, De Santis L
Hum Reprod. 2023 Apr 7:dead067. doi: 10.1093/humrep/dead067. Online ahead of print.. 2023 doi:
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Humidified atmosphere in a time-lapse embryo culture system does not improve ongoing pregnancy rate: a retrospective propensity score model study derived from 496 first ICSI cycles.
Bartolacci A, Borini A, Cimadomo D, Fabozzi G, Maggiulli R, Lagalla C, Pignataro D, dell'Aquila M, Parodi F, Patria G, Zacà C, Ubaldi FM, Rienzi L, Coticchio G
J Assist Reprod Genet. 2023 May 3. doi: 10.1007/s10815-023-02818-8. Online ahead of print. . 2023 doi:
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From a cycle-by-cycle to a multi-cycle treatment planning: the next relevant shift in perspective needed in ART?
Faustini F, Cimadomo D, Ubaldi FM, Rienzi L
Fertil Steril. 2023 May 8:S0015-0282(23)00372-2. doi: 10.1016/j.fertnstert.2023.05.001. Online ahead of print. . 2023 doi:
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Opening the black box: why do euploid blastocysts fail to implant? A systematic review and meta-analysis.
Cimadomo D, Rienzi L, Conforti A, Forman E, Canosa S, Innocenti F, Poli M, Hynes J, Gemmell L, Vaiarelli A, Alviggi C, Ubaldi FM, Capalbo A
Hum Reprod Update. 2023 May 16:dmad010. doi: 10.1093/humupd/dmad010. Online ahead of print.. 2023 doi:
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Low-quality evidence from a randomized controlled trial due to an inappropriate IVF setting to challenge Dual Stimulation strategy.
Ubaldi FM, Vaiarelli A, Cimadomo D, Cerrillo M, Rienzi L, Garcia-Velasco JA
Hum Reprod. 2023 Jun 5:dead108. doi: 10.1093/humrep/dead108. Online ahead of print.. 2023 doi:
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How should the best human embryo in vitro be? Current and future challenges for embryo selection.
Cimadomo D, Innocenti F, Taggi M, Saturno G, Campitiello MR, Guido M, Vaiarelli A, Ubaldi FM, Rienzi L
Minerva Obstet Gynecol. 2023 Jun 16. doi: 10.23736/S2724-606X.23.05296-X. Online ahead of print.. 2023 doi:
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Cryostorage management of reproductive cells and tissues in ART: status, needs, opportunities, and potential new challenges
Canosa S, Maggiulli R, Cimadomo D, Innocenti F, Fabozzi G, Gennarelli G, Revelli A, Bongioanni F, Vaiarelli A, Ubaldi FM, Rienzi L, Palmer GA, Nijs M
Reproductive BioMedicine Online Available online 22 June 202 In press. 2022 doi:
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Endocrine-Disrupting Chemicals, Gut Microbiota, and Human (In)Fertility-It Is Time to Consider the Triad.
Fabozzi G, Rebuzzini P, Cimadomo D, Allori M, Franzago M, Stuppia L, Garagna S, Ubaldi FM, Zuccotti M, Rienzi L
Cells. 2022 Oct 22;11(21):3335. doi: 10.3390/cells11213335. . 2022 doi:
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Multi- and Transgenerational Effects of Environmental Toxicants on Mammalian Reproduction.
Rebuzzini P, Fabozzi G, Cimadomo D, Ubaldi FM, Rienzi L, Zuccotti M, Garagna S
Cells. 2022 Oct 9;11(19):3163. doi: 10.3390/cells11193163.. 2022 doi:
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The role of thyroid function in female and male infertility: a narrative review.
Mazzilli R, Medenica S, Di Tommaso AM, Fabozzi G, Zamponi V, Cimadomo D, Rienzi L, Ubaldi FM, Watanabe M, Faggiano A, La Vignera S, Defeudis G
J Endocrinol Invest. 2023 Jan;46(1):15-26. doi: 10.1007/s40618-022-01883-7. Epub 2022 Aug 9. . 2022 doi:
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Human blastocyst spontaneous collapse is associated with worse morphological quality and higher degeneration and aneuploidy rates: a comprehensive analysis standardized through artificial intelligence.
Cimadomo D, Marconetto A, Trio S, Chiappetta V, Innocenti F, Albricci L, Erlich I, Ben-Meir A, Har-Vardi I, Kantor B, Sakov A, Coticchio G, Borini A, Ubaldi FM, Rienzi L
Hum Reprod. 2022 Sep 30;37(10):2291-2306. doi: 10.1093/humrep/deac175.. 2022 doi:
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Avoid mixing apples and oranges: blastocysts diagnosed with uniform whole chromosome aneuploidies are reproductively incompetent and their transfer is harmful.
Capalbo A, Cimadomo D, Rienzi L, Garcìa-Velasco JA, Simòn C, Ubaldi FM
Hum Reprod. 2022 Aug 25;37(9):2213-2214. doi: 10.1093/humrep/deac149.. 2022 doi:
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Personalized Nutrition in the Management of Female Infertility: New Insights on Chronic Low-Grade Inflammation.
Fabozzi G, Verdone G, Allori M, Cimadomo D, Tatone C, Stuppia L, Franzago M, Ubaldi N, Vaiarelli A, Ubaldi FM, Rienzi L, Gennarelli G
Nutrients. 2022 May 3;14(9):1918. doi: 10.3390/nu14091918.. 2022 doi:
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How slow is too slow? A comprehensive portrait of Day 7 blastocysts and their clinical value standardized through artificial intelligence.
Cimadomo D, Soscia D, Casciani V, Innocenti F, Trio S, Chiappetta V, Albricci L, Maggiulli R, Erlich I, Ben-Meir A, Har-Vardi I, Vaiarelli A, Ubaldi FM, Rienzi L
Hum Reprod. 2022 May 30;37(6):1134-1147. doi: 10.1093/humrep/deac080. . 2022 doi:
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Neither rationale nor scientific evidence exist to support that double stimulation is potentially unsafe.
Casarini L, Vaiarelli A, Cimadomo D, Santi D, Simoni M, Garcìa-Velasco JA, Alviggi C, La Marca A, Rienzi L, Ubaldi FM
Hum Reprod. 2022 Jul 30;37(8):1949-1950. doi: 10.1093/humrep/deac064.. 2022 doi:
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Maternal effect factors that contribute to oocytes developmental competence: an update.
Innocenti F, Fiorentino G, Cimadomo D, Soscia D, Garagna S, Rienzi L, Ubaldi FM, Zuccotti M, SIERR
J Assist Reprod Genet. 2022 Apr;39(4):861-871. doi: 10.1007/s10815-022-02434-y. Epub 2022 Feb 15.. 2022 doi:
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Second stimulation in the same ovarian cycle: an option to fully-personalize the treatment in poor prognosis patients undergoing PGT-A.
Vaiarelli A, Cimadomo D, Gennarelli G, Guido M, Alviggi C, Conforti A, Livi C, Revelli A, Colamaria S, Argento C, Giuliani M, De Angelis C, Matteo M, Canosa S, D'Alfonso A, Cimadomo V, Rienzi L, Ubaldi FM
J Assist Reprod Genet. 2022 Mar;39(3):663-673. doi: 10.1007/s10815-022-02409-z. Epub 2022 Feb 7.. 2022 doi:
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The effect of extended cryo-storage following vitrification on embryo competence: a systematic review and meta-analysis.
Canosa S, Cimadomo D, Conforti A, Maggiulli R, Giancani A, Tallarita A, Golia F, Fabozzi G, Vaiarelli A, Gennarelli G, Revelli A, Bongioanni F, Alviggi C, Ubaldi FM, Rienzi L, SIERR
J Assist Reprod Genet. 2022 Apr;39(4):873-882. doi: 10.1007/s10815-022-02405-3. Epub 2022 Feb 4.. 2022 doi:
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Fertility counseling in women with hereditary cancer syndromes.
Somigliana E, Costantini MP, Filippi F, Terenziani M, Riccaboni A, Nicotra V, Rago R, Paffoni A, Mencaglia L, Magnolfi S, Zuccarello D, Rienzi L, Spinella F, Capalbo A, Scaravelli G, Testa S, MUTAGENS Special Interest Group on parenting and fertility
Crit Rev Oncol Hematol. 2022 Mar;171:103604. doi: 10.1016/j.critrevonc.2022.103604. Epub 2022 Jan 25.. 2022 doi:
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Lights and shadows of preimplantation genetic testing for aneuploidy: better focusing on the accurate report of nonmosaic aneuploidies.
Cimadomo D, Rienzi L, Ubaldi FM, Capalbo A
Fertil Steril. 2022 Feb;117(2):324-325. doi: 10.1016/j.fertnstert.2021.12.002. Epub 2021 Dec 26.. 2022 doi:
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Clinical, obstetric and perinatal outcomes after vitrified-warmed euploid blastocyst transfer are independent of cryo-storage duration.
Cimadomo D, Fabozzi G, Dovere L, Maggiulli R, Albricci L, Innocenti F, Soscia D, Giancani A, Vaiarelli A, Guido M, Ubaldi FM, Rienzi L
Reprod Biomed Online. 2022 Feb;44(2):221-227. doi: 10.1016/j.rbmo.2021.09.027. Epub 2021 Oct 8.. 2022 doi:
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Inter-centre reliability in embryo grading across several IVF clinics is limited: implications for embryo selection.
Cimadomo D, Sosa Fernandez L, Soscia D, Fabozzi G, Benini F, Cesana A, Dal Canto MB, Maggiulli R, Muzzì S, Scarica C, Rienzi L, De Santis L
Reprod Biomed Online. 2022 Jan;44(1):39-48. doi: 10.1016/j.rbmo.2021.09.022. Epub 2021 Oct 6. . 2022 doi:
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Mosaic human preimplantation embryos and their developmental potential in a prospective, non-selection clinical trial.
Capalbo A, Poli M, Rienzi L, Girardi L, Patassini C, Fabiani M, Cimadomo D, Benini F, Farcomeni A, Cuzzi J, Rubio C, Albani E, Sacchi L, Vaiarelli A, Figliuzzi M, Findikli N, Coban O, Boynukalin FK, Vogel I, Hoffmann E, Livi C, Levi-Setti PE, Ubaldi FM, Simón C
Am J Hum Genet. 2021 Dec 2;108(12):2238-2247. doi: 10.1016/j.ajhg.2021.11.002. Epub 2021 Nov 18.. 2021 doi:
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Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives.
Maggiulli R, Vaiarelli A, Cimadomo D, Giancani A, Tacconi L, Fabozzi G, Ubaldi FM, Rienzi L
J Vis Exp. 2021 Sep 16;(175). doi: 10.3791/61963.. 2021 doi:
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Measuring success in IVF is a complex multidisciplinary task: time for a consensus?
Rienzi L, Cimadomo D, Vaiarelli A, Gennarelli G, Holte J, Livi C, Aura Masip M, Uher P, Fabozzi G, Ubaldi FM
Reprod Biomed Online. 2021 Nov;43(5):775-778. doi: 10.1016/j.rbmo.2021.08.012. Epub 2021 Aug 20. . 2021 doi:
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Maternal body mass index associates with blastocyst euploidy and live birth rates: the tip of an iceberg?
Fabozzi G, Cimadomo D, Allori M, Vaiarelli A, Colamaria S, Argento C, Amendola MG, Innocenti F, Soscia D, Maggiulli R, Mazzilli R, Ubaldi N, Iussig B, Marchetti M, Rienzi L, Ubaldi FM
Reprod Biomed Online. 2021 Oct;43(4):645-654. doi: 10.1016/j.rbmo.2021.07.006. Epub 2021 Jul 22.. 2021 doi:
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Severe male factor in in vitro fertilization: definition, prevalence, and treatment. An update.
Mazzilli R, Vaiarelli A, Dovere L, Cimadomo D, Ubaldi N, Ferrero S, Rienzi L, Lombardo F, Lenzi A, Tournaye H, Ubaldi FM
Asian J Androl. 2022 Mar-Apr;24(2):125-134. doi: 10.4103/aja.aja_53_21.. 2021 doi:
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In vitro fertilization and andrology laboratory in 2030: expert visions.
Campbell A, Gardner DK, Meseguer M, Miller KA, Montag M, Palermo GD, Cheung S, Keating D, Xie P, Rosenwaks Z, Rienzi L, Innocenti F, Cimadomo D, Ubaldi FM, Sakkas D, Tucker MJ, Nel-Themaat L, Simon C
Fertil Steril. 2021 Jul;116(1):4-12. doi: 10.1016/j.fertnstert.2021.05.088.. 2021 doi:
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In vitro fertilization and andrology laboratories in 2030.
Simon C, Campbell A, Gardner DK, Meseguer M, Miller KA, Montag M, Palermo GD, Cheung S, Keating D, Xie P, Rosenwaks Z, Rienzi L, Innocenti F, Cimadomo D, Ubaldi FM, Sakkas D, Tucker MJ, Nel-Themaat L
Fertil Steril. 2021 Jul;116(1):2-3. doi: 10.1016/j.fertnstert.2021.05.089.. 2021 doi:
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Clinical validity and utility of preconception expanded carrier screening for the management of reproductive genetic risk in IVF and general population.
Capalbo A, Fabiani M, Caroselli S, Poli M, Girardi L, Patassini C, Favero F, Cimadomo D, Vaiarelli A, Simon C, Rienzi LF, Ubaldi FM
Hum Reprod. 2021 Jun 18;36(7):2050-2061. doi: 10.1093/humrep/deab087. 2021 doi:
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Is a randomized controlled design sufficient for a trial to be valuable?
Ubaldi FM, Cimadomo D, Vaiarelli A, Rienzi L
Hum Reprod. 2021 Jul 19;36(8):2416-2417. doi: 10.1093/humrep/deab114.. 2021 doi:
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Oocyte competence is independent of the ovulation trigger adopted: a large observational study in a setting that entails vitrified-warmed single euploid blastocyst transfer.
Cimadomo D, Vaiarelli A, Petriglia C, Fabozzi G, Ferrero S, Schimberni M, Argento C, Colamaria S, Giuliani M, Ubaldi N, Rienzi L, Ubaldi FM
J Assist Reprod Genet. 2021 Jun;38(6):1419-1427. doi: 10.1007/s10815-021-02124-1. Epub 2021 Mar 4.. 2021 doi:
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Is it in our patients' blood? On a quest for predictors of blastocysts' aneuploidy rate.
Cimadomo D, Rienzi L, Ubaldi FM
Fertil Steril. 2021 Apr;115(4):888-889. doi: 10.1016/j.fertnstert.2021.02.013. Epub 2021 Feb 26.. 2021 doi:
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Reply: 'Second stimulation in the same ovarian cycle', probably a terminology more appropriate than 'luteal phase stimulation' in the DuoStim protocol.
Vaiarelli A, Cimadomo D, Rienzi L, Ubaldi FM
Hum Reprod. 2021 May 17;36(6):1723-1724. doi: 10.1093/humrep/deab018.. 2021 doi:
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Leave the past behind: women's reproductive history shows no association with blastocysts' euploidy and limited association with live birth rates after euploid embryo transfers.
Cimadomo D, Capalbo A, Dovere L, Tacconi L, Soscia D, Giancani A, Scepi E, Maggiulli R, Vaiarelli A, Rienzi L, Ubaldi FM
Hum Reprod. 2021 Mar 18;36(4):929-940. doi: 10.1093/humrep/deab014.. 2021 doi:
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The Impact of Unbalanced Maternal Nutritional Intakes on Oocyte Mitochondrial Activity: Implications for Reproductive Function.
Fabozzi G, Iussig B, Cimadomo D, Vaiarelli A, Maggiulli R, Ubaldi N, Ubaldi FM, Rienzi L
Antioxidants (Basel). 2021 Jan 11;10(1):91. doi: 10.3390/antiox10010091.. 2021 doi:
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When embryology meets genetics: the definition of developmentally incompetent preimplantation embryos (DIPE)-the consensus of two Italian scientific societies.
Cimadomo D, Capalbo A, Scarica C, Sosa Fernandez L, Rienzi L, Ciriminna R, Minasi MG, Novelli A, De Santis L, Zuccarello D
J Assist Reprod Genet. 2021 Feb;38(2):319-331. doi: 10.1007/s10815-020-02015-x. Epub 2020 Nov 24.. 2021 doi:
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Metaphase-II oocyte competence is unlinked to the gonadotrophins used for ovarian stimulation: a matched case-control study in women of advanced maternal age.
Vaiarelli A, Cimadomo D, Scarafia C, Innocenti F, Amendola MG, Fabozzi G, Casarini L, Conforti A, Alviggi C, Gennarelli G, Benedetto C, Guido M, Borini A, Rienzi L, Ubaldi FM
J Assist Reprod Genet. 2023 Jan;40(1):169-177. doi: 10.1007/s10815-022-02684-w. Epub 2022 Dec 31.. 2023 doi:
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Improved clinical utility of preimplantation genetic testing through the integration of ploidy and common pathogenic microdeletions analyses.
Caroselli S, Figliuzzi M, Picchetta L, Cogo F, Zambon P, Pergher I, Girardi L, Patassini C, Poli M, Bakalova D, Cimadomo D, Findikli N, Coban O, Serdarogullari M, Favero F, Bortolato S, Anastasi A, Capodanno F, Gallinelli A, Brancati F, Rienzi L, Ubaldi FM, Jimenez-Almazán J, Blesa-Jarque D, Miravet-Valenciano J, Rubio C, Simòn C, Capalbo A
Hum Reprod. 2023 Feb 22:dead033. doi: 10.1093/humrep/dead033. Online ahead of print.. 2023 doi:
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Recombinant human luteinizing hormone co-treatment in ovarian stimulation for assisted reproductive technology in women of advanced reproductive age: a systematic review and meta-analysis of randomized controlled trials.
Conforti A, Esteves SC, Humaidan P, Longobardi S, D'Hooghe T, Orvieto R, Vaiarelli A, Cimadomo D, Rienzi L, Ubaldi FM, Zullo F, Alviggi C
Reprod Biol Endocrinol. 2021 Jun 21;19(1):91. doi: 10.1186/s12958-021-00759-4.. 2021 doi:
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Improving Reporting of Clinical Studies Using the POSEIDON Criteria: POSORT Guidelines.
Esteves SC, Conforti A, Sunkara SK, Carbone L, Picarelli S, Vaiarelli A, Cimadomo D, Rienzi L, Ubaldi FM, Zullo F, Andersen CY, Orvieto R, Humaidan P, Alviggi C
Front Endocrinol (Lausanne). 2021 Mar 19;12:587051. doi: 10.3389/fendo.2021.587051. eCollection 2021.. 2021 doi:
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Natural Cycle Results in Lower Implantation Failure than Ovarian Stimulation in Advanced-Age Poor Responders Undergoing IVF: Fertility Outcomes from 585 Patients.
De Marco MP, Montanari G, Ruscito I, Giallonardo A, Ubaldi FM, Rienzi L, Costanzi F, Caserta D, Schimberni M, Schimberni M
Reprod Sci. 2021 Jul;28(7):1967-1973. doi: 10.1007/s43032-020-00455-5. Epub 2021 Jan 22.. 2021 doi:
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Blastulation rates of sibling oocytes in two IVF culture media: an evidence-based workflow to implement newly commercialized products.
Fabozzi G, Albricci L, Cimadomo D, Amendola MG, Sanges F, Maggiulli R, Ubaldi FM, Rienzi L
Reprod Biomed Online. 2021 Feb;42(2):311-322. doi: 10.1016/j.rbmo.2020.10.017. Epub 2020 Nov 4.. 2021 doi:
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Endometriosis shows no impact on the euploid blastocyst rate per cohort of inseminated metaphase-II oocytes: A case-control study.
Vaiarelli A, Venturella R, Cimadomo D, Conforti A, Pedri S, Bitonti G, Iussig B, Gentile C, Alviggi E, Santopaolo S, Zullo F, Rienzi L, Ubaldi FM
Eur J Obstet Gynecol Reprod Biol. 2021 Jan;256:205-210. doi: 10.1016/j.ejogrb.2020.11.024. Epub 2020 Nov 11.. 2021 doi:
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Perinatal and obstetric outcomes in singleton pregnancies following fresh versus cryopreserved blastocyst transfer: a meta-analysis.
Conforti A, Picarelli S, Carbone L, La Marca A, Venturella R, Vaiarelli A, Cimadomo D, Zullo F, Rienzi L, Ubaldi FM, Alviggi C
Reprod Biomed Online. 2021 Feb;42(2):401-412. doi: 10.1016/j.rbmo.2020.09.029. Epub 2020 Oct 5.. 2021 doi:
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Septate uterus and reproductive outcomes: let's get serious about this.
Alonso Pacheco L, Ata B, Bettocchi S, Campo R, Carugno J, Checa MA, de Angelis C, Di Spiezio Sardo A, Donnez J, Farrugia M, Ferro J, Franchini M, Garzon S, Gianaroli L, Gergolet M, Gubbini G, Gordts S, Grimbizis G, Haimovich S, Laganà AS, Li TC, Mencaglia L, Rienzi L, Saravelos S, Soares SR, Tanos V, Ubeda A, Ubaldi FM, Van Herendael B, Vereczkey A, Vitagliano A, Vitale SG, Zullo F
Hum Reprod. 2020 Nov 1;35(11):2627-2629. doi: 10.1093/humrep/deaa230.. 2020 doi:
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The euploid blastocysts obtained after luteal phase stimulation show the same clinical, obstetric and perinatal outcomes as follicular phase stimulation-derived ones: a multicenter study.
Vaiarelli A, Cimadomo D, Alviggi E, Sansone A, Trabucco E, Dusi L, Buffo L, Barnocchi N, Fiorini F, Colamaria S, Giuliani M, Argento C, Rienzi L, Ubaldi FM
Hum Reprod. 2020 Nov 1;35(11):2598-2608. doi: 10.1093/humrep/deaa203.. 2020 doi:
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Which key performance indicators are most effective in evaluating and managing an in vitro fertilization laboratory?
Fabozzi G, Cimadomo D, Maggiulli R, Vaiarelli A, Ubaldi FM, Rienzi L
Fertil Steril. 2020 Jul;114(1):9-15. doi: 10.1016/j.fertnstert.2020.04.054. Epub 2020 Jun 9. . 2020 doi:
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The dawn of the future: 30 years from the first biopsy of a human embryo. The detailed history of an ongoing revolution.
Cimadomo D, Rienzi L, Capalbo A, Rubio C, Innocenti F, García-Pascual CM, Ubaldi FM, Handyside A
Hum Reprod Update. 2020 Jun 18;26(4):453-473. doi: 10.1093/humupd/dmaa019.. 2020 doi:
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COVID-19 and ART: the view of the Italian Society of Fertility and Sterility and Reproductive Medicine.
Vaiarelli A, Bulletti C, Cimadomo D, Borini A, Alviggi C, Ajossa S, Anserini P, Gennarelli G, Guido M, Levi-Setti PE, Palagiano A, Palermo R, Savasi V, Pellicer A, Rienzi L, Ubaldi FM
Reprod Biomed Online. 2020 Jun;40(6):755-759. doi: 10.1016/j.rbmo.2020.04.003. Epub 2020 Apr 8.. 2020 doi:
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DuoStim - a reproducible strategy to obtain more oocytes and competent embryos in a short time-frame aimed at fertility preservation and IVF purposes. A systematic review.
Vaiarelli A, Cimadomo D, Petriglia C, Conforti A, Alviggi C, Ubaldi N, Ledda S, Ferrero S, Rienzi L, Ubaldi FM
Ups J Med Sci. 2020 May;125(2):121-130. doi: 10.1080/03009734.2020.1734694. Epub 2020 Apr 25.. 2020 doi:
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Definition of a clinical strategy to enhance the efficacy, efficiency and safety of egg donation cycles with imported vitrified oocytes.
Rienzi L, Cimadomo D, Maggiulli R, Vaiarelli A, Dusi L, Buffo L, Amendola MG, Colamaria S, Giuliani M, Bruno G, Stoppa M, Ubaldi FM
Hum Reprod. 2020 Apr 28;35(4):785-795. doi: 10.1093/humrep/deaa009.. 2020 doi:
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Incidence, Origin, and Predictive Model for the Detection and Clinical Management of Segmental Aneuploidies in Human Embryos.
Girardi L, Serdarogullari M, Patassini C, Poli M, Fabiani M, Caroselli S, Coban O, Findikli N, Boynukalin FK, Bahceci M, Chopra R, Canipari R, Cimadomo D, Rienzi L, Ubaldi F, Hoffmann E, Rubio C, Simon C, Capalbo A
Am J Hum Genet. 2020 Apr 2;106(4):525-534. doi: 10.1016/j.ajhg.2020.03.005. Epub 2020 Mar 26.. 2020 doi:
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Validation of ART Calculator for Predicting the Number of Metaphase II Oocytes Required for Obtaining at Least One Euploid Blastocyst for Transfer in Couples Undergoing in vitro Fertilization/Intracytoplasmic Sperm Injection.
Esteves SC, Yarali H, Ubaldi FM, Carvalho JF, Bento FC, Vaiarelli A, Cimadomo D, Özbek İY, Polat M, Bozdag G, Rienzi L, Alviggi C
Front Endocrinol (Lausanne). 2020 Jan 24;10:917. doi: 10.3389/fendo.2019.00917. eCollection 2019.. 2020 doi:
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The effect of ICSI-related procedural timings and operators on the outcome.
Maggiulli R, Cimadomo D, Fabozzi G, Papini L, Dovere L, Ubaldi FM, Rienzi L
Hum Reprod. 2020 Jan 1;35(1):32-43. doi: 10.1093/humrep/dez234.. 2020 doi:
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Time of morulation and trophectoderm quality are predictors of a live birth after euploid blastocyst transfer: a multicenter study.
Rienzi L, Cimadomo D, Delgado A, Minasi MG, Fabozzi G, Gallego RD, Stoppa M, Bellver J, Giancani A, Esbert M, Capalbo A, Remohì J, Greco E, Ubaldi FM, Meseguer M
Fertil Steril. 2019 Dec;112(6):1080-1093.e1. doi: 10.1016/j.fertnstert.2019.07.1322.. 2019 doi:
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Luteal phase after conventional stimulation in the same ovarian cycle might improve the management of poor responder patients fulfilling the Bologna criteria: a case series.
Vaiarelli A, Cimadomo D, Conforti A, Schimberni M, Giuliani M, D'Alessandro P, Colamaria S, Alviggi C, Rienzi L, Ubaldi FM
Fertil Steril. 2020 Jan;113(1):121-130. doi: 10.1016/j.fertnstert.2019.09.012. Epub 2019 Dec 16.. 2020 doi:
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The POSEIDON Criteria and Its Measure of Success Through the Eyes of Clinicians and Embryologists.
Esteves SC, Alviggi C, Humaidan P, Fischer R, Andersen CY, Conforti A, Bühler K, Sunkara SK, Polyzos NP, Galliano D, Grynberg M, Yarali H, Özbek IY, Roque M, Vuong LN, Banker M, Rienzi L, Vaiarelli A, Cimadomo D, Ubaldi FM
Front Endocrinol (Lausanne). 2019 Nov 20;10:814. doi: 10.3389/fendo.2019.00814. eCollection 2019.. 2019 doi:
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Similar miRNomic signatures characterize the follicular fluids collected after follicular and luteal phase stimulations in the same ovarian cycle.
Cimadomo D, Carmelo R, Parrotta EI, Scalise S, Santamaria G, Alviggi E, De Angelis MT, Sarro G, Vaiarelli A, Venturella R, Rienzi L, Zullo F, Ubaldi FM, Cuda G
.J Assist Reprod Genet. 2020 Jan;37(1):149-158. doi: 10.1007/s10815-019-01607-6. Epub 2019 Nov 7. . 2020 doi:
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Correction to: Contribution of cryopreservation to the cumulative live birth rate: a large multicentric cycle-based data analysis from the Italian National Registry.
Scaravelli G, Levi-Setti PE, Livi C, La Sala G, Ubaldi FM, Greco E, Coccia ME, Borini A, Revelli A, Ricci G, Vigiliano V, De Luca R, Bolli S, Rienzi L
J Assist Reprod Genet. 2019 Nov;36(11):2297. doi: 10.1007/s10815-019-01581-z.. 2019 doi:
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Chromosome errors in human eggs shape natural fertility over reproductive life span.
Gruhn JR, Zielinska AP, Shukla V, Blanshard R, Capalbo A, Cimadomo D, Nikiforov D, Chan AC, Newnham LJ, Vogel I, Scarica C, Krapchev M, Taylor D, Kristensen SG, Cheng J, Ernst E, Bjørn AB, Colmorn LB, Blayney M, Elder K, Liss J, Hartshorne G, Grøndahl ML, Rienzi L, Ubaldi F, McCoy R, Lukaszuk K, Andersen CY, Schuh M, Hoffmann ER
Science. 2019 Sep 27;365(6460):1466-1469. doi: 10.1126/science.aav7321.. 2019 doi:
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Contribution of cryopreservation to the cumulative live birth rate: a large multicentric cycle-based data analysis from the Italian National Registry.
Scaravelli G, Levi-Setti PE, Livi C, La Sala G, Ubaldi FM, Greco E, Coccia ME, Borini A, Revelli A, Ricci G, Vigiliano V, De Luca R, Bolli S, Rienzi L, Collaborators
J Assist Reprod Genet. 2019 Nov;36(11):2287-2295. doi: 10.1007/s10815-019-01566-y. Epub 2019 Aug 28.. 2019 doi:
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Definition and validation of a custom protocol to detect miRNAs in the spent media after blastocyst culture: searching for biomarkers of implantation.
Cimadomo D, Rienzi L, Giancani A, Alviggi E, Dusi L, Canipari R, Noli L, Ilic D, Khalaf Y, Ubaldi FM, Capalbo A
Hum Reprod. 2019 Sep 29;34(9):1746-1761. doi: 10.1093/humrep/dez119.. 2019 doi:
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Human Blastocyst Biopsy and Vitrification.
Maggiulli R, Giancani A, Cimadomo D, Ubaldi FM, Rienzi L
J Vis Exp. 2019 Jul 26;(149). doi: 10.3791/59625.. 2019 doi:
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Sperm DNA fragmentation to predict embryo development, implantation, and miscarriage: still an open question.
Rienzi L, Mazzilli R, Ubaldi FM
Fertil Steril. 2019 Sep;112(3):466. doi: 10.1016/j.fertnstert.2019.05.016. Epub 2019 Jul 1.. 2019 doi:
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Looking past the appearance: a comprehensive description of the clinical contribution of poor-quality blastocysts to increase live birth rates during cycles with aneuploidy testing.
Cimadomo D, Soscia D, Vaiarelli A, Maggiulli R, Capalbo A, Ubaldi FM, Rienzi L
Hum Reprod. 2019 Jul 8;34(7):1206-1214. doi: 10.1093/humrep/dez078.. 2019 doi:
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Embryonic cell-free DNA versus trophectoderm biopsy for aneuploidy testing: concordance rate and clinical implications.
Rubio C, Rienzi L, Navarro-Sánchez L, Cimadomo D, García-Pascual CM, Albricci L, Soscia D, Valbuena D, Capalbo A, Ubaldi F, Simón C
Fertil Steril. 2019 Sep;112(3):510-519. doi: 10.1016/j.fertnstert.2019.04.038. Epub 2019 Jun 11.. 2019 doi:
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Non-invasive mitochondrial DNA quantification on Day 3 predicts blastocyst development: a prospective, blinded, multi-centric study.
Stigliani S, Orlando G, Massarotti C, Casciano I, Bovis F, Anserini P, Ubaldi FM, Remorgida V, Rienzi L, Scaruffi P
Mol Hum Reprod. 2019 Sep 1;25(9):527-537. doi: 10.1093/molehr/gaz032.. 2019 doi:
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The main will of the patients of a private Italian IVF clinic for their aneuploid/affected blastocysts would be donation to research: a currently forbidden choice.
Faustini F, Forte M, Capalbo A, Cimadomo D, Ubaldi FM, Rienzi L
J Assist Reprod Genet. 2019 Aug;36(8):1555-1560. doi: 10.1007/s10815-019-01465-2. Epub 2019 May 27.. 2019 doi:
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State of the art and emerging drug therapies for female infertility.
Venturella R, Vaiarelli A, Cimadomo D, Pedri S, Lico D, Mazzilli R, Mocciaro R, Rienzi L, Di Carlo C, Ubaldi FM, Zullo F
Gynecol Endocrinol. 2019 Oct;35(10):835-841. doi: 10.1080/09513590.2019.1603289. Epub 2019 Apr 29.. 2019 doi:
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Perspectives in Gamete and Embryo Cryopreservation.
Rienzi LF, Iussig B, Dovere L, Fabozzi G, Cimadomo D, Ubaldi FM
Semin Reprod Med. 2018 Sep;36(5):253-264. doi: 10.1055/s-0038-1677463. Epub 2019 Apr 4. . 2019 doi:
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Double stimulation in the same ovarian cycle (DuoStim) is an intriguing strategy to improve oocyte yield and the number of competent embryos in a short timeframe.
Vaiarelli A, Cimadomo D, Argento C, Ubaldi N, Trabucco E, Drakopoulos P, Venturella R, Conforti A, Alviggi C, Rienzi L, Ubaldi FM
Minerva Ginecol. 2019 Oct;71(5):372-376. doi: 10.23736/S0026-4784.19.04390-9. Epub 2019 Mar 4.. 2019 doi:
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Advanced Maternal Age in IVF: Still a Challenge? The Present and the Future of Its Treatment.
Ubaldi FM, Cimadomo D, Vaiarelli A, Fabozzi G, Venturella R, Maggiulli R, Mazzilli R, Ferrero S, Palagiano A, Rienzi L
Front Endocrinol (Lausanne). 2019 Feb 20;10:94. doi: 10.3389/fendo.2019.00094. eCollection 2019.. 2019 doi:
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A brief history of oocyte cryopreservation: Arguments and facts.
Iussig B, Maggiulli R, Fabozzi G, Bertelle S, Vaiarelli A, Cimadomo D, Ubaldi FM, Rienzi L
Acta Obstet Gynecol Scand. 2019 May;98(5):550-558. doi: 10.1111/aogs.13569. Epub 2019 Mar 25.. 2019 doi:
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An integrated investigation of oocyte developmental competence: expression of key genes in human cumulus cells, morphokinetics of early divisions, blastulation, and euploidy.
Scarica C, Cimadomo D, Dovere L, Giancani A, Stoppa M, Capalbo A, Ubaldi FM, Rienzi L, Canipari R
J Assist Reprod Genet. 2019 May;36(5):875-887. doi: 10.1007/s10815-019-01410-3. Epub 2019 Feb 1.. 2019 doi:
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Diagnostic efficacy of blastocoel fluid and spent media as sources of DNA for preimplantation genetic testing in standard clinical conditions.
Capalbo A, Romanelli V, Patassini C, Poli M, Girardi L, Giancani A, Stoppa M, Cimadomo D, Ubaldi FM, Rienzi L
Fertil Steril. 2018 Oct;110(5):870-879.e5. doi: 10.1016/j.fertnstert.2018.05.031.. 2018 doi:
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Associations of blastocyst features, trophectoderm biopsy and other laboratory practice with post-warming behavior and implantation.
Cimadomo D, Capalbo A, Levi-Setti PE, Soscia D, Orlando G, Albani E, Parini V, Stoppa M, Dovere L, Tacconi L, Ievoli E, Maggiulli R, Ubaldi FM, Rienzi L
Hum Reprod. 2018 Nov 1;33(11):1992-2001. doi: 10.1093/humrep/dey291.. 2018 doi:
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Inconclusive chromosomal assessment after blastocyst biopsy: prevalence, causative factors and outcomes after re-biopsy and re-vitrification. A multicenter experience.
Cimadomo D, Rienzi L, Romanelli V, Alviggi E, Levi-Setti PE, Albani E, Dusi L, Papini L, Livi C, Benini F, Smeraldi A, Patassini C, Ubaldi FM, Capalbo A
Hum Reprod. 2018 Oct 1;33(10):1839-1846. doi: 10.1093/humrep/dey282.. 2018 doi:
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Impact of Maternal Age on Oocyte and Embryo Competence.
Cimadomo D, Fabozzi G, Vaiarelli A, Ubaldi N, Ubaldi FM, Rienzi L
Front Endocrinol (Lausanne). 2018 Jun 29;9:327. doi: 10.3389/fendo.2018.00327. eCollection 2018.. 2018 doi:
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Double Stimulation in the Same Ovarian Cycle (DuoStim) to Maximize the Number of Oocytes Retrieved From Poor Prognosis Patients: A Multicenter Experience and SWOT Analysis.
Vaiarelli A, Cimadomo D, Trabucco E, Vallefuoco R, Buffo L, Dusi L, Fiorini F, Barnocchi N, Bulletti FM, Rienzi L, Ubaldi FM
Front Endocrinol (Lausanne). 2018 Jun 14;9:317. doi: 10.3389/fendo.2018.00317. eCollection 2018.. 2018 doi:
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Luteal phase anovulatory follicles result in the production of competent oocytes: intra-patient paired case-control study comparing follicular versus luteal phase stimulations in the same ovarian cycle.
Cimadomo D, Vaiarelli A, Colamaria S, Trabucco E, Alviggi C, Venturella R, Alviggi E, Carmelo R, Rienzi L, Ubaldi FM
Hum Reprod. 2018 Aug 1;33(8):1442-1448. doi: 10.1093/humrep/dey217.. 2018 doi:
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Prevalence of XXY karyotypes in human blastocysts: multicentre data from 7549 trophectoderm biopsies obtained during preimplantation genetic testing cycles in IVF.
Mazzilli R, Cimadomo D, Rienzi L, Capalbo A, Levi Setti PE, Livi C, Vizziello D, Foresta C, Ferlin A, Ubaldi FM
Hum Reprod. 2018 Jul 1;33(7):1355-1363. doi: 10.1093/humrep/dey110.. 2018 doi:
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Continuous embryo culture elicits higher blastulation but similar cumulative delivery rates than sequential: a large prospective study.
Cimadomo D, Scarica C, Maggiulli R, Orlando G, Soscia D, Albricci L, Romano S, Sanges F, Ubaldi FM, Rienzi L
J Assist Reprod Genet. 2018 Jul;35(7):1329-1338. doi: 10.1007/s10815-018-1195-4. Epub 2018 May 3.. 2018 doi:
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What is new in the management of poor ovarian response in IVF?
Vaiarelli A, Cimadomo D, Ubaldi N, Rienzi L, Ubaldi FM
Curr Opin Obstet Gynecol. 2018 Jun;30(3):155-162. doi: 10.1097/GCO.0000000000000452.. 2018 doi:
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Progesterone for preparation of the endometrium for frozen-thawed blastocyst transfer in vitro fertilization cycles: a prospective study on patients' opinions on a new subcutaneous formulation.
Venturella R, Vaiarelli A, Buffo L, D'alessandro P, Colamaria S, Pedri S, Di Carlo C, Alviggi E, Forte M, Faustini F, Zullo F, Rienzi L, Ubaldi FM
Gynecol Endocrinol. 2018 Sep;34(9):766-771. doi: 10.1080/09513590.2018.1451508. Epub 2018 Mar 16.. 2018 doi:
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Effect of the male factor on the clinical outcome of intracytoplasmic sperm injection combined with preimplantation aneuploidy testing: observational longitudinal cohort study of 1,219 consecutive cycles.
Mazzilli R, Cimadomo D, Vaiarelli A, Capalbo A, Dovere L, Alviggi E, Dusi L, Foresta C, Lombardo F, Lenzi A, Tournaye H, Alviggi C, Rienzi L, Ubaldi FM
Fertil Steril. 2017 Dec;108(6):961-972.e3. doi: 10.1016/j.fertnstert.2017.08.033. Epub 2017 Oct 3.. 2017 doi:
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Human female meiosis revised: new insights into the mechanisms of chromosome segregation and aneuploidies from advanced genomics and time-lapse imaging.
Capalbo A, Hoffmann ER, Cimadomo D, Ubaldi FM, Rienzi L
Hum Reprod Update. 2017 Nov 1;23(6):706-722. doi: 10.1093/humupd/dmx026.. 2017 doi:
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Abnormally fertilized oocytes can result in healthy live births: improved genetic technologies for preimplantation genetic testing can be used to rescue viable embryos in in vitro fertilization cycles.
Capalbo A, Treff N, Cimadomo D, Tao X, Ferrero S, Vaiarelli A, Colamaria S, Maggiulli R, Orlando G, Scarica C, Scott R, Ubaldi FM, Rienzi L
Fertil Steril. 2017 Dec;108(6):1007-1015.e3. doi: 10.1016/j.fertnstert.2017.08.004. Epub 2017 Sep 15.. 2017 doi:
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Preimplantation genetic diagnosis for aneuploidy testing in women older than 44 years: a multicenter experience.
Ubaldi FM, Cimadomo D, Capalbo A, Vaiarelli A, Buffo L, Trabucco E, Ferrero S, Albani E, Rienzi L, Levi Setti PE
Fertil Steril. 2017 May;107(5):1173-1180. doi: 10.1016/j.fertnstert.2017.03.007. Epub 2017 Apr 19.. 2017 doi:
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Reply: Detecting mosaicism in trophectoderm biopsies.
Capalbo A, Ubaldi F, Rienzi L, Scott R, Treff N
Hum Reprod. 2017 Mar 1;32(3):714-715. doi: 10.1093/humrep/dew347.. 2017 doi:
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Diagnosis and clinical management of duplications and deletions.
Capalbo A, Rienzi L, Ubaldi FM
Fertil Steril. 2017 Jan;107(1):12-18. doi: 10.1016/j.fertnstert.2016.11.002.. 2017 doi:
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PGS for recurrent pregnancy loss: still an open question.
Rienzi L, Capalbo A, Vajta G, Ubaldi FM
Hum Reprod. 2017 Feb;32(2):476-477. doi: 10.1093/humrep/dew311. Epub 2016 Dec 13.. 2017 doi:
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Oocyte, embryo and blastocyst cryopreservation in ART: systematic review and meta-analysis comparing slow-freezing versus vitrification to produce evidence for the development of global guidance.
Rienzi L, Gracia C, Maggiulli R, LaBarbera AR, Kaser DJ, Ubaldi FM, Vanderpoel S, Racowsky C
Hum Reprod Update. 2017 Mar 1;23(2):139-155. doi: 10.1093/humupd/dmw038. . 2017 doi:
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Human Embryos Created by Embryo Splitting Secrete Significantly Lower Levels of miRNA-30c.
Noli L, Capalbo A, Dajani Y, Cimadomo D, Bvumbe J, Rienzi L, Ubaldi FM, Ogilvie C, Khalaf Y, Ilic D
Stem Cells Dev. 2016 Dec 15;25(24):1853-1862. doi: 10.1089/scd.2016.0212. Epub 2016 Oct 17.. 2016 doi:
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Detecting mosaicism in trophectoderm biopsies: current challenges and future possibilities.
Capalbo A, Ubaldi FM, Rienzi L, Scott R, Treff N
Hum Reprod. 2017 Mar 1;32(3):492-498. doi: 10.1093/humrep/dew250.. 2017 doi:
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5,X product of conception after preimplantation genetic diagnosis and euploid embryo transfer: evidence of a spontaneous conception confirmed by DNA fingerprinting.
Bettio D, Capalbo A, Albani E, Rienzi L, Achille V, Venci A, Ubaldi FM, Levi Setti PE
Reprod Biol Endocrinol. 2016 Sep 6;14(1):55. doi: 10.1186/s12958-016-0190-9.. 2016 doi:
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Pre-implantation genetic testing in ART: who will benefit and what is the evidence?
Vaiarelli A, Cimadomo D, Capalbo A, Orlando G, Sapienza F, Colamaria S, Palagiano A, Bulletti C, Rienzi L, Ubaldi FM
.J Assist Reprod Genet. 2016 Oct;33(10):1273-1278. doi: 10.1007/s10815-016-0785-2. Epub 2016 Aug 5.. 2016 doi:
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Implementing PGD/PGD-A in IVF clinics: considerations for the best laboratory approach and management.
Capalbo A, Romanelli V, Cimadomo D, Girardi L, Stoppa M, Dovere L, Dell'Edera D, Ubaldi FM, Rienzi L
J Assist Reprod Genet. 2016 Oct;33(10):1279-1286. doi: 10.1007/s10815-016-0768-3. Epub 2016 Jul 16. . 2016 doi:
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Electronic witness system in IVF-patients perspective.
Forte M, Faustini F, Maggiulli R, Scarica C, Romano S, Ottolini C, Farcomeni A, Palagiano A, Capalbo A, Ubaldi FM, Rienzi L
J Assist Reprod Genet. 2016 Sep;33(9):1215-22. doi: 10.1007/s10815-016-0759-4. Epub 2016 Jul 7.. 2016 doi:
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Failure mode and effects analysis of witnessing protocols for ensuring traceability during PGD/PGS cycles.
Cimadomo D, Ubaldi FM, Capalbo A, Maggiulli R, Scarica C, Romano S, Poggiana C, Zuccarello D, Giancani A, Vaiarelli A, Rienzi L
Reprod Biomed Online. 2016 Sep;33(3):360-9. doi: 10.1016/j.rbmo.2016.06.002. Epub 2016 Jun 23.. 2016 doi:
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Generation of meiomaps of genome-wide recombination and chromosome segregation in human oocytes.
Ottolini CS, Capalbo A, Newnham L, Cimadomo D, Natesan SA, Hoffmann ER, Ubaldi FM, Rienzi L, Handyside AH
Nat Protoc. 2016 Jul;11(7):1229-43. doi: 10.1038/nprot.2016.075. Epub 2016 Jun 16.. 2016 doi:
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The why, the how and the when of PGS 2.0: current practices and expert opinions of fertility specialists, molecular biologists, and embryologists.
Sermon K, Capalbo A, Cohen J, Coonen E, De Rycke M, De Vos A, Delhanty J, Fiorentino F, Gleicher N, Griesinger G, Grifo J, Handyside A, Harper J, Kokkali G, Mastenbroek S, Meldrum D, Meseguer M, Montag M, Munné S, Rienzi L, Rubio C, Scott K, Scott R, Simon C, Swain J, Treff N, Ubaldi F, Vassena R, Vermeesch JR, Verpoest W, Wells D, Geraedts J
Mol Hum Reprod. 2016 Aug;22(8):845-57. doi: 10.1093/molehr/gaw034. Epub 2016 Jun 2. . 2016 doi:
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Follicular versus luteal phase ovarian stimulation during the same menstrual cycle (DuoStim) in a reduced ovarian reserve population results in a similar euploid blastocyst formation rate: new insight in ovarian reserve exploitation.
Ubaldi FM, Capalbo A, Vaiarelli A, Cimadomo D, Colamaria S, Alviggi C, Trabucco E, Venturella R, Vajta G, Rienzi L
Fertil Steril. 2016 Jun;105(6):1488-1495.e1. doi: 10.1016/j.fertnstert.2016.03.002. Epub 2016 Mar 25.. 2016 doi:
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The Impact of Biopsy on Human Embryo Developmental Potential during Preimplantation Genetic Diagnosis.
Cimadomo D, Capalbo A, Ubaldi FM, Scarica C, Palagiano A, Canipari R, Rienzi L
Biomed Res Int. 2016;2016:7193075. doi: 10.1155/2016/7193075. Epub 2016 Jan 28.. 2016 doi:
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Early protein profile of human embryonic secretome.
Foresta C, Ubaldi FM, Rienzi L, Franchin C, Pivato M, Romano S, Guidolin D, De Caro R, Ferlin A, De Toni L
Front Biosci (Landmark Ed). 2016 Jan 1;21(3):620-34. doi: 10.2741/4410.. 2016 doi:
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Artificial oocyte activation with calcium ionophore does not cause a widespread increase in chromosome segregation errors in the second meiotic division of the oocyte.
Capalbo A, Ottolini CS, Griffin DK, Ubaldi FM, Handyside AH, Rienzi L
Fertil Steril. 2016 Mar;105(3):807-814.e2. doi: 10.1016/j.fertnstert.2015.11.017. Epub 2015 Dec 1.. 2016 doi:
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Consistent and reproducible outcomes of blastocyst biopsy and aneuploidy screening across different biopsy practitioners: a multicentre study involving 2586 embryo biopsies.
Capalbo A, Ubaldi FM, Cimadomo D, Maggiulli R, Patassini C, Dusi L, Sanges F, Buffo L, Venturella R, Rienzi L
Hum Reprod. 2016 Jan;31(1):199-208. doi: 10.1093/humrep/dev294. Epub 2015 Dec 4.. 2016 doi:
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New approaches for multifactor preimplantation genetic diagnosis of monogenic diseases and aneuploidies from a single biopsy.
Capalbo A, Rienzi L, Ubaldi FM
Fertil Steril. 2016 Feb;105(2):297-8. doi: 10.1016/j.fertnstert.2015.10.039. Epub 2015 Nov 21.. 2016 doi:
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Developmental clock compromises human twin model created by embryo splitting.
Noli L, Dajani Y, Capalbo A, Bvumbe J, Rienzi L, Ubaldi FM, Ogilvie C, Khalaf Y, Ilic D
Hum Reprod. 2015 Dec;30(12):2774-84. doi: 10.1093/humrep/dev252. Epub 2015 Oct 21. . 2015 doi:
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MicroRNAs in spent blastocyst culture medium are derived from trophectoderm cells and can be explored for human embryo reproductive competence assessment.
Capalbo A, Ubaldi FM, Cimadomo D, Noli L, Khalaf Y, Farcomeni A, Ilic D, Rienzi L
Fertil Steril. 2016 Jan;105(1):225-35.e1-3. doi: 10.1016/j.fertnstert.2015.09.014. Epub 2015 Oct 9.. 2016 doi:
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Failure mode and effects analysis of witnessing protocols for ensuring traceability during IVF.
Rienzi L, Bariani F, Dalla Zorza M, Romano S, Scarica C, Maggiulli R, Nanni Costa A, Ubaldi FM
Reprod Biomed Online. 2015 Oct;31(4):516-22. doi: 10.1016/j.rbmo.2015.06.018. Epub 2015 Jul 7.. 2015 doi:
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Reduction of multiple pregnancies in the advanced maternal age population after implementation of an elective single embryo transfer policy coupled with enhanced embryo selection: pre- and post-intervention study.
Ubaldi FM, Capalbo A, Colamaria S, Ferrero S, Maggiulli R, Vajta G, Sapienza F, Cimadomo D, Giuliani M, Gravotta E, Vaiarelli A, Rienzi L
Hum Reprod. 2015 Sep;30(9):2097-106. doi: 10.1093/humrep/dev159. Epub 2015 Jul 5.. 2015 doi:
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Oocyte versus embryo cryopreservation for fertility preservation in cancer patients: guaranteeing a women's autonomy.
Rienzi L, Ubaldi FM
J Assist Reprod Genet. 2015 Aug;32(8):1195-6. doi: 10.1007/s10815-015-0507-1. Epub 2015 Jun 17.. 2015 doi:
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Genome-wide maps of recombination and chromosome segregation in human oocytes and embryos show selection for maternal recombination rates.
Ottolini CS, Newnham L, Capalbo A, Natesan SA, Joshi HA, Cimadomo D, Griffin DK, Sage K, Summers MC, Thornhill AR, Housworth E, Herbert AD, Rienzi L, Ubaldi FM, Handyside AH, Hoffmann ER
Nat Genet. 2015 Jul;47(7):727-735. doi: 10.1038/ng.3306. Epub 2015 May 18.. 2015 doi:
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Loop electrosurgical excision procedure: a risk for spontaneous abortion?
Ubaldi FM, Vaiarelli A, Rienzi L
.Fertil Steril. 2015 Apr;103(4):904-5. doi: 10.1016/j.fertnstert.2015.01.016. Epub 2015 Feb 3.. 2015 doi:
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Open versus closed systems for vitrification of human oocytes and embryos.
Vajta G, Rienzi L, Ubaldi FM
Reprod Biomed Online. 2015 Apr;30(4):325-33. doi: 10.1016/j.rbmo.2014.12.012. Epub 2015 Jan 12.. 2015 doi:
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No evidence of association between blastocyst aneuploidy and morphokinetic assessment in a selected population of poor-prognosis patients: a longitudinal cohort study.
Rienzi L, Capalbo A, Stoppa M, Romano S, Maggiulli R, Albricci L, Scarica C, Farcomeni A, Vajta G, Ubaldi FM
Reprod Biomed Online. 2015 Jan;30(1):57-66. doi: 10.1016/j.rbmo.2014.09.012. Epub 2014 Oct 5.. 2015 doi:
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Comparison of array comparative genomic hybridization and quantitative real-time PCR-based aneuploidy screening of blastocyst biopsies.
Capalbo A, Treff NR, Cimadomo D, Tao X, Upham K, Ubaldi FM, Rienzi L, Scott RT Jr
Eur J Hum Genet. 2015 Jul;23(7):901-6. doi: 10.1038/ejhg.2014.222. Epub 2014 Oct 29.. 2015 doi:
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Management of poor responders in IVF: is there anything new?
Ubaldi F, Vaiarelli A, D'Anna R, Rienzi L
Biomed Res Int. 2014;2014:352098. doi: 10.1155/2014/352098. Epub 2014 Jul 20. . 2014 doi:
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Correlation between standard blastocyst morphology, euploidy and implantation: an observational study in two centers involving 956 screened blastocysts.
Capalbo A, Rienzi L, Cimadomo D, Maggiulli R, Elliott T, Wright G, Nagy ZP, Ubaldi FM
Hum Reprod. 2014 Jun;29(6):1173-81. doi: 10.1093/humrep/deu033. Epub 2014 Feb 26.. 2014 doi:
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FISH reanalysis of inner cell mass and trophectoderm samples of previously array-CGH screened blastocysts shows high accuracy of diagnosis and no major diagnostic impact of mosaicism at the blastocyst stage.
Capalbo A, Wright G, Elliott T, Ubaldi FM, Rienzi L, Nagy ZP
Hum Reprod. 2013 Aug;28(8):2298-307. doi: 10.1093/humrep/det245. Epub 2013 Jun 5.. 2013 doi:
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Reply: Questions about the accuracy of polar body analysis for preimplantation genetic screening.
Capalbo A, Bono S, Spizzichino L, Biricik A, Baldi M, Colamaria S, Ubaldi FM, Rienzi L, Fiorentino F
Hum Reprod. 2013 Jun;28(6):1733-6. doi: 10.1093/humrep/det070. Epub 2013 Mar 26.. 2013 doi:
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Sequential comprehensive chromosome analysis on polar bodies, blastomeres and trophoblast: insights into female meiotic errors and chromosomal segregation in the preimplantation window of embryo development.
Capalbo A, Bono S, Spizzichino L, Biricik A, Baldi M, Colamaria S, Ubaldi FM, Rienzi L, Fiorentino F
Hum Reprod. 2013 Feb;28(2):509-18. doi: 10.1093/humrep/des394. Epub 2012 Nov 11.. 2013 doi:
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Consistent and predictable delivery rates after oocyte vitrification: an observational longitudinal cohort multicentric study.
Rienzi L, Cobo A, Paffoni A, Scarduelli C, Capalbo A, Vajta G, Remohí J, Ragni G, Ubaldi FM
Hum Reprod. 2012 Jun;27(6):1606-12. doi: 10.1093/humrep/des088. Epub 2012 Mar 22.. 2012 doi:
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New culture devices in ART.
Rienzi L, Vajta G, Ubaldi F
Placenta. 2011 Sep;32 Suppl 3:S248-51. doi: 10.1016/j.placenta.2011.06.018. Epub 2011 Jul 18.. 2011 doi:
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The worldwide frozen embryo reservoir: methodologies to achieve optimal results.
Capalbo A, Rienzi L, Buccheri M, Maggiulli R, Sapienza F, Romano S, Colamaria S, Iussig B, Giuliani M, Palagiano A, Ubaldi F
Ann N Y Acad Sci. 2011 Mar;1221:32-9. doi: 10.1111/j.1749-6632.2010.05931.x.. 2011 doi:
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Predictive value of oocyte morphology in human IVF: a systematic review of the literature.
Rienzi L, Vajta G, Ubaldi F
Hum Reprod Update. 2011 Jan-Feb;17(1):34-45. doi: 10.1093/humupd/dmq029. Epub 2010 Jul 16.. 2011 doi:
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Cumulative ongoing pregnancy rate achieved with oocyte vitrification and cleavage stage transfer without embryo selection in a standard infertility program.
Ubaldi F, Anniballo R, Romano S, Baroni E, Albricci L, Colamaria S, Capalbo A, Sapienza F, Vajta G, Rienzi L
Hum Reprod. 2010 May;25(5):1199-205. doi: 10.1093/humrep/deq046. Epub 2010 Feb 25. . 2010 doi:
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Embryo development of fresh 'versus' vitrified metaphase II oocytes after ICSI: a prospective randomized sibling-oocyte study.
Rienzi L, Romano S, Albricci L, Maggiulli R, Capalbo A, Baroni E, Colamaria S, Sapienza F, Ubaldi F
Hum Reprod. 2010 Jan;25(1):66-73. doi: 10.1093/humrep/dep346. Epub 2009 Oct 27.. 2010 doi:
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Possible impact of LH-containing gonadotrophins on diploidy rates in preimplantation embryos.
Ubaldi F, Rienzi L
Hum Reprod. 2009 May;24(5):1238-9; author reply 1239-40. doi: 10.1093/humrep/den477. Epub 2009 Feb 27.. 2009 doi:
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Morphological selection of gametes.
Ubaldi F, Rienzi L
Placenta. 2008 Oct;29 Suppl B:115-20. doi: 10.1016/j.placenta.2008.08.009. Epub 2008 Aug 31.. 2008 doi:
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Future challenges for clinical embryologists.
Rienzi L, Fauser B
Reprod Biomed Online. 2021 Dec;43(6):973-975. doi: 10.1016/j.rbmo.2021.10.001. Epub 2021 Oct 12.. 2021 doi:
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Educational needs of fertility healthcare professionals using ART: a multi-country mixed-methods study.
Péloquin S, Garcia-Velasco JA, Blockeel C, Rienzi L, de Mesmaeker G, Lazure P, Beligotti F, Murray S
Reprod Biomed Online. 2021 Sep;43(3):434-445. doi: 10.1016/j.rbmo.2021.06.020. Epub 2021 Jul 2. . 2021 doi:
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SARS-CoV-2 persistence at subzero temperatures.
Scarica C, Parmegiani L, Rienzi L, Anastasi A, Cimadomo D, Klinger FG, Licata E, Sosa Fernandez L, De Santis L
J Assist Reprod Genet. 2021 Apr;38(4):779-781. doi: 10.1007/s10815-021-02094-4. Epub 2021 Feb 5.. 2021 doi:
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Practical Clinical and Diagnostic Pathway for the Investigation of the Infertile Couple.
Garolla A, Pizzol D, Carosso AR, Borini A, Ubaldi FM, Calogero AE, Ferlin A, Lanzone A, Tomei F, Engl B, Rienzi L, De Santis L, Coticchio G, Smith L, Cannarella R, Anastasi A, Menegazzo M, Stuppia L, Corsini C, Foresta C
Front Endocrinol (Lausanne). 2021 Jan 19;11:591837. doi: 10.3389/fendo.2020.591837. eCollection 2020.. 2021 doi:
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Phthalates and Bisphenol A: Presence in Blood Serum and Follicular Fluid of Italian Women Undergoing Assisted Reproduction Techniques.
Paoli D, Pallotti F, Dima AP, Albani E, Alviggi C, Causio F, Dioguardi CC, Conforti A, Ciriminna R, Fabozzi G, Giuffrida G, Gualtieri R, Minasi MG, Ochetti S, Pisaturo V, Racca C, Rienzi L, Sarcina E, Scarica C, Tomasi G, Verlengia C, Villeggia R, Zullo F, Lenzi A, Botrè F, De Santis L
Toxics. 2020 Oct 21;8(4):91. doi: 10.3390/toxics8040091.. 2020 doi:
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Cryopreserved Gamete and Embryo Transport: Proposed Protocol and Form Templates-SIERR (Italian Society of Embryology, Reproduction, and Research).
Paoli D, Dal Canto M, Baldi E, Cervi M, Ciotti PM, Ciriminna R, Dabizzi S, Farace D, Garello C, Garolla A, Giacchetta D, Gualtieri R, Menegazzo M, Minasi MG, Oneta M, Pisaturo V, Rienzi L, Scarica C, Taliani G, De Santis L
Biopreserv Biobank. 2021 Feb;19(1):27-32. doi: 10.1089/bio.2020.0080. Epub 2020 Oct 7.. 2021 doi:
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Assessment and management of the risk of SARS-CoV-2 infection in an IVF laboratory.
Maggiulli R, Giancani A, Fabozzi G, Dovere L, Tacconi L, Amendola MG, Cimadomo D, Ubaldi FM, Rienzi L
Reprod Biomed Online. 2020 Sep;41(3):385-394. doi: 10.1016/j.rbmo.2020.06.017. Epub 2020 Jun 27.. 2020 doi:
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Corrigendum. Definition of a clinical strategy to enhance the efficacy, efficiency and safety of egg donation cycles with imported vitrified oocytes.
Rienzi L, Cimadomo D, Maggiulli R, Vaiarelli A, Dusi L, Buffo L, Amendola MG, Colamaria S, Giuliani M, Bruno G, Stoppa M, Ubaldi FM
Hum Reprod. 2020 Aug 1;35(8):1944. doi: 10.1093/humrep/deaa145.. 2020 doi:
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Multicenter prospective study of concordance between embryonic cell-free DNA and trophectoderm biopsies from 1301 human blastocysts.
Rubio C, Navarro-Sánchez L, García-Pascual CM, Ocali O, Cimadomo D, Venier W, Barroso G, Kopcow L, Bahçeci M, Kulmann MIR, López L, De la Fuente E, Navarro R, Valbuena D, Sakkas D, Rienzi L, Simón C
Am J Obstet Gynecol. 2020 Nov;223(5):751.e1-751.e13. doi: 10.1016/j.ajog.2020.04.035. Epub 2020 May 26.. 2020 doi:
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Breakthroughs and challenges of modern developmental biology and reproductive medicine.
Fishel S, Hadjantonakis AK, Plusa B, Rienzi L, Yamanaka Y, Suwińska A, Ajduk A
Int J Dev Biol. 2019;63(3-4-5):77-82. doi: 10.1387/ijdb.180398aa.. 2019 doi:
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Biochemical pregnancy loss after frozen embryo transfer seems independent of embryo developmental stage and chromosomal status.
Vaiarelli A, Cimadomo D, Patrizio P, Venturella R, Orlando G, Soscia D, Giancani A, Capalbo A, Rienzi L, Ubaldi FM
Reprod Biomed Online. 2018 Sep;37(3):349-357. doi: 10.1016/j.rbmo.2018.05.019. Epub 2018 Jun 30.. 2018 doi:
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The International Glossary on Infertility and Fertility Care, 2017.
Zegers-Hochschild F, Adamson GD, Dyer S, Racowsky C, de Mouzon J, Sokol R, Rienzi L, Sunde A, Schmidt L, Cooke ID, Simpson JL, van der Poel S
Hum Reprod. 2017 Sep 1;32(9):1786-1801. doi: 10.1093/humrep/dex234.. 2017 doi:
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Mosaicism between trophectoderm and inner cell mass.
Capalbo A, Rienzi L
Fertil Steril. 2017 May;107(5):1098-1106. doi: 10.1016/j.fertnstert.2017.03.023. Epub 2017 Apr 19. . 2017 doi:
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Birthweight and the effects of culture media.
Thompson J, Davies M, Pool T, Rienzi L, Nagy PZ, Hardarson T, Sakkas D, Gardner D
Hum Reprod. 2017 Mar 1;32(3):717-718. doi: 10.1093/humrep/dew337.. 2017 doi:
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45,X product of conception after preimplantation genetic diagnosis and euploid embryo transfer: evidence of a spontaneous conception confirmed by DNA fingerprinting.
Bettio D, Capalbo A, Albani E, Rienzi L, Achille V, Venci A, Ubaldi FM, Levi Setti PE
Reprod Biol Endocrinol. 2016 Sep 6;14(1):55. doi: 10.1186/s12958-016-0190-9.. 2016 doi:
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Blastocyst culture using single versus sequential media in clinical IVF: a systematic review and meta-analysis of randomized controlled trials.
Sfontouris IA, Martins WP, Nastri CO, Viana IG, Navarro PA, Raine-Fenning N, van der Poel S, Rienzi L, Racowsky C
J Assist Reprod Genet. 2016 Oct;33(10):1261-1272. doi: 10.1007/s10815-016-0774-5. Epub 2016 Aug 5.. 2016 doi:
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Revised guidelines for good practice in IVF laboratories (2015).
ESHRE Guideline Group on Good Practice in IVF Labs, De los Santos MJ, Apter S, Coticchio G, Debrock S, Lundin K, Plancha CE, Prados F, Rienzi L, Verheyen G, Woodward B, Vermeulen N
Hum Reprod. 2016 Apr;31(4):685-6. doi: 10.1093/humrep/dew016. Epub 2016 Feb 17.. 2016 doi:
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A cautionary note against embryo aneuploidy risk assessment using time-lapse imaging.
Ottolini C, Rienzi L, Capalbo A
Reprod Biomed Online. 2014 Mar;28(3):273-5. doi: 10.1016/j.rbmo.2013.10.015. Epub 2013 Oct 26.. 2014 doi:
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The oocyte.
Rienzi L, Balaban B, Ebner T, Mandelbaum J
Hum Reprod. 2012 Aug;27 Suppl 1:i2-21. doi: 10.1093/humrep/des200. Epub 2012 Jul 18.. 2012 doi:
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Hermetical goblets for cryostorage of human vitrified specimens.
Parmegiani L, Rienzi L
Hum Reprod. 2011 Nov;26(11):3204-5. doi: 10.1093/humrep/der308. Epub 2011 Sep 9.. 2011 doi:
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Improved clinical utility of preimplantation genetic testing through the integration of ploidy and common pathogenic microdeletions analyses.
Caroselli S, Figliuzzi M, Picchetta L, Cogo F, Zambon P, Pergher I, Girardi L, Patassini C, Poli M, Bakalova D, Cimadomo D, Findikli N, Coban O, Serdarogullari M, Favero F, Bortolato S, Anastasi A, Capodanno F, Gallinelli A, Brancati F, Rienzi L, Ubaldi FM, Jimenez-Almazán J, Blesa-Jarque D, Miravet-Valenciano J, Rubio C, Simòn C, Capalbo A
Hum Reprod. 2023 Feb 22:dead033. doi: 10.1093/humrep/dead033. Online ahead of print.. 2023 doi:
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Biomechanical forces and signals operating in the ovary during folliculogenesis and their dysregulation: implications for fertility.
Fiorentino G, Cimadomo D, Innocenti F, Soscia D, Vaiarelli A, Ubaldi FM, Gennarelli G, Garagna S, Rienzi L, Zuccotti M
Hum Reprod Update. 2023 Jan 5;29(1):1-23. doi: 10.1093/humupd/dmac031.. 2023 doi:
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Maternal age affects pronuclear and chromatin dynamics, morula compaction and cell polarity, and blastulation of human embryos.
Ezoe K, Miki T, Akaike H, Shimazaki K, Takahashi T, Tanimura Y, Amagai A, Sawado A, Mogi M, Kaneko S, Ueno S, Coticchio G, Cimadomo D, Borini A, Rienzi L, Kato K
Hum Reprod. 2023 Jan 16:dead001. doi: 10.1093/humrep/dead001. Online ahead of print.. 2023 doi:
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Towards Automation in IVF: Pre-Clinical Validation of a Deep Learning-Based Embryo Grading System during PGT-A Cycles.
Cimadomo D, Chiappetta V, Innocenti F, Saturno G, Taggi M, Marconetto A, Casciani V, Albricci L, Maggiulli R, Coticchio G, Ahlström A, Berntsen J, Larman M, Borini A, Vaiarelli A, Ubaldi FM, Rienzi L
J Clin Med. 2023 Feb 23;12(5):1806. doi: 10.3390/jcm12051806.. 2023 doi:
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Avoid mixing apples and oranges: blastocysts diagnosed with uniform whole chromosome aneuploidies are reproductively incompetent and their transfer is harmful.
Capalbo A, Cimadomo D, Rienzi L, Garcìa-Velasco JA, Simòn C, Ubaldi FM
Hum Reprod. . 2022 doi: 10.1093/humrep/deac149
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Neither rationale nor scientific evidence exist to support that double stimulation is potentially unsafe.
Casarini L, Vaiarelli A, Cimadomo D, Santi D, Simoni M, Garcìa-Velasco JA, Alviggi C, La Marca A, Rienzi L, Ubaldi FM
Hum Reprod. 2022 Apr 8:deac064. Online ahead of print. 2022 doi: 10.1093/humrep/deac064