Marcos Meseguer, Ph.D.

Biography

Dr. Marcos Meseguer received his B.Sc. degree in Biological Sciences from the University of Valencia in Spain. He then performed a pre-doctoral fellowship in St Mary´s Hospital, Manchester University, United Kingdom, and received his Ph.D. Degree in Obstetrics and Gynecoloy and the European Doctor Degree in 2002 from the University of Valencia, Spain. He has also a master degree in Research Methods; Design and Statistics from Universidad Autónoma de Barcelona, Spain.
Dr.Meseguer is currently the Scientific Supervisor and Senior Embryologist at the IVI Valencia IVF unit. Previously, he was co-Director of the Andrology Laboratory at the Instituto Valenciano de Infertilidad (IVI).

Dr. Meseguer has received the Prize Paper Award of the American Society of Reproductive Medicine, three times the Lalor Foundation International Award from the American Society of Andrology, three times the research award from the Spanish Society of Fertility and four times the research award from the Spanish Society of Embrology. He received the Robert Edwards prize paper award from RBM online and is ASRM star award winner. The primary areas of his research are embryology and male infertility.
As Principal Investigator, his work has been funded through 16 projects sponsored by the Spanish Government, including five EUREKA projects (granted to high quality technological projects) supported by the European Community. He has one international patent.
He has published over 145 scientific articles, with 5400 citations and h-index of 43, including the most cited paper in Human Reproduction during 2013. Additionally published 50 reviews or book chapters, edited the first time-lapse book and made more than 500 presentations at national and international congresses. He has been the Director of 13 Doctoral Thesis all qualified with “Cum Laude”, and currently is directing 6 PhD candidates. In addition, he is also Statistics Advisor of Equipo IVI and Associate Professor of the Master’s in Biotechnology at University of Valencia.

Education and Training

BS	University of Valencia (1998)
PhD in Obstetrics and Gynecology	University of Valencia (2002)
European Doctor Degree in Biological Sciences	University of Valencia (2002)
Master Statistics and Research Methods	University of Barcelona (2009)

Honors and recognition

Honorable Member Spanish Society of Embryology	2017
ASRM star award winner	2017
Research award from the Spanish Society of Embryology	2015
Robert Edwards prize paper award from RBM online	2014
Spanish Society of Fertility Research Award	2014
Research award from the Spanish Society of Embryology	2013
Spanish Society of Fertility Research Award	2012
Research award from the Spanish Society of Embryology	2011
Research award from the Spanish Society of Embryology	2009
Lalor Foundation International Award from the American Society of Andrology	2008
Lalor Foundation International Award from the American Society of Andrology	2005
Lalor Foundation International Award from the American Society of Andrology	2003
Prize paper Journal of Spanish Society of Fertility	2002

Publications

"Quality is not an act, it is a habit." Reflection on the role of the fertilization rate in the quality control strategies of assisted reproduction treatments.
Valera MÁ, Meseguer M

Fertil Steril. 2021 doi:

Blastocyst formation is similar in obese and normal weight women: a morphokinetic study.
Bellver J, Brandão P, Alegre L, Meseguer M

Hum Reprod. 2021 doi:

In vitro fertilization and andrology laboratories in 2030.
Simon C, Campbell A, Gardner DK, Meseguer M, Miller KA, Montag M, Palermo GD, Cheung S, Keating D, Xie P, Rosenwaks Z, Rienzi L, Innocenti F, Cimadomo D, Ubaldi FM, Sakkas D, Tucker MJ, Nel-Themaat L

Fertil Steril. Jul. 2021 doi: 10.1016/j.fertnstert.2021.05.089

In vitro fertilization and andrology laboratory in 2030: expert visions
Campbell A, Gardner DK, Meseguer M, MillerKA, Montag M, PalermoGD, Cheung S, Keating D, Xie P, Rosenwaks Z, Rienzi L, Innocenti F, Cimadomo D, Ubaldi FM, Sakkas D, Tucker MJ, Nel-Themaat L, Simon C

Fertil Steril. Jul. 2021 doi: 10.1016/j.fertnstert.2021.05.088

Differential sperm proteomic profiles according to pregnancy achievement in intracytoplasmic sperm injection cycles: a pilot study.
Rivera-Egea R, Sota N, Gonzalez-Martín R, Meseguer M, Remohi J, Garrido N, Dominguez F

J Assist Reprod Genet. Apr. 2021 doi: 10.1007/s10815-021-02098-0

Are we approaching automated assisted reproductive technology? Sperm analysis, Oocyte manipulation and insemination.
Casciani V, Galliano D, Franasiak JM, Mariani G, Meseguer M

F&S Reviews. Mar. 2021 doi: 10.1016/j.xfnr.2021.03.002

The morphokinetic signature of mosaic embryos: evidence in support of their own genetic identity
Martin A, Rodrigo L, Beltran D, Meseguer M, Rubio C, Mercader A, de Los Santos M J

Fertil Steril. Mar. 2021 doi: 10.1016/j.fertnstert.2020.12.031

The journey toward personalized embryo selection algorithms
Meseguer M, Valera MA

Fertil Steril. Mar. 2021 doi: 10.1016/j.fertnstert.2021.01.039

Prediction of embryo survival and live birth rates after cryo-transfers of vitrified blastocysts according to morphology and day of blastulation: a retrospective study including 11936 blastocysts
Coello A, Nohales M, Meseguer M, de Los Santos M J, Remohi J, Cobo A,

Reprod BioMed Online. Feb. 2021 doi: 10.1016/j.rbmo.2021.02.013

Fertility technologies and how to optimize laboratory performance to support the shortening of time to birth of a healthy singleton: a Delphi consensus.
Coticchio G, Behr B, Campbell A, Meseguer M, Morbeck DE, Pisaturo V, Plancha CE, Sakkas D, Xu Y, D'Hooghe T, Cottell E, Lundin K

J Assist Reprod Genet. Feb. 2021 doi: 10.1007/s00192-021-04706-0

Differential sperm proteomic profiles according to pregnancy achievement in intracytoplasmic sperm injection cycles: a pilot study
Rivera-Egea R, Sota N, Gonzalez-Martin R, Meseguer M, Remohi J, Garrido N, Dominguez F,

J Assist Reprod Genet. 2021 Apr. doi: 10.1007/s10815-021-02098-0

Prediction of embryo survival and live birth rates after cryotransfers of vitrified blastocysts
Coello A, Nohales M, Meseguer M, de Los Santos M J, Remohi J, Cobo A,

Reprod Biomed Online. 2021 May. doi: 10.1016/j.rbmo.2021.02.013

The morphokinetic signature of mosaic embryos: evidence in support of their own genetic identity
Martin A, Rodrigo L, Beltran D, Meseguer M, Rubio C, Mercader A, Jose de Los Santos M,

Fertil Steril. 2021 Mar. doi: 10.1016/j.fertnstert.2020.12.031

The journey toward personalized embryo selection algorithms
Meseguer M, Valera M A,

Fertil Steril. 2021 Apr. doi: 10.1016/j.fertnstert.2021.01.039

Fertility technologies and how to optimize laboratory performance to support the shortening of time to birth of a healthy singleton: a Delphi consensus
Coticchio G, Behr B, Campbell A, Meseguer M, Morbeck D E, Pisaturo V, Plancha C E, Sakkas D, Xu Y, D'Hooghe T, Cottell E, Lundin K,

J Assist Reprod Genet. 2021 18-Feb. doi: 10.1007/s10815-021-02077-5

An artificial intelligence model based on the proteomic profile of euploid embryos and blastocyst morphology: a preliminary study
Bori L, Dominguez F, Fernandez E I, Del Gallego R, Alegre L, Hickman C, Quinonero A, Nogueira M F G, Rocha J C, Meseguer M,

Reprod Biomed Online. 2021 Feb. doi: 10.1016/j.rbmo.2020.09.031

Assessment of embryo implantation potential with a cloud-based automatic software
Alegre L, Del Gallego R, Bori L, Loewke K, Maddah M, Aparicio-Ruiz B, Palma-Govea A P, Marcos J, Meseguer M,

Reprod Biomed Online. 2021 Jan. doi: 10.1016/j.rbmo.2020.09.032

Euploidy prediction: possible or impossible? Closer or further away?
Meseguer M,

Fertil Steril. 2021 Feb. doi: 10.1016/j.fertnstert.2020.09.138

Are we approaching automated assisted reproductive technology? Sperm analysis, oocyte manipulation and insemination
Casciani V, Galliano D, Franasiak J M, Mariani G, Meseguer M,

F&S Reviews. 2021 doi: 10.1016/j.xfnr.2021.03.002

Female obesity increases the risk of miscarriage of euploid embryos
Cozzolino M, Garcia-Velasco J A, Meseguer M, Pellicer A, Bellver J,

Fertil Steril. 2020 Nov. doi: 10.1016/j.fertnstert.2020.09.139

Ai in the treatment of fertility: Key considerations
Swain J, VerMilyea M T, Meseguer M, Ezcurra D, Fertility A I F G,

J Assist Reprod Genet. 2020 Nov. doi: 10.1007/s10815-020-01950-z

Novel and conventional embryo parameters as input data for artificial neural networks: an artificial intelligence model applied for prediction of the implantation potential
Bori L, Paya E, Alegre L, Viloria T A, Remohi J, Naranjo V, Meseguer M,

Fertil Steril. 2020 Dec. doi: 10.1016/j.fertnstert.2020.08.023

Preimplantation genetic testing for aneuploidy in patients with partial X monosomy using their own oocytes: is this a suitable indication?
Giles J, Meseguer M, Mercader A, Rubio C, Alegre L, Vidal C, Trabalon M, Bosch E,

Fertil Steril. 2020 Aug. doi: 10.1016/j.fertnstert.2020.04.003

Managing the IVF laboratory during a pandemic: international perspectives from laboratory managers
Hickman C, Rogers S, Huang G, MacArthur S, Meseguer M, Nogueira D, Portela R, Rienzi L, Sharp T, Ye H,

Reprod Biomed Online. 2020 Aug. doi: 10.1016/j.rbmo.2020.05.006

COVID-19 should be a novel indication for fertility preservation
Geber S, Prates N, Sampaio M, Valle M, Meseguer M,

JBRA Assist Reprod. 2020 Jul. doi: 10.5935/1518-0557.20200048

Deep inside the pandemic, from inactivity to action: let's be ready
Meseguer M, Niederberger C, Pellicer A,

Fertil Steril. 2020 Jun. doi: 10.1016/j.fertnstert.2020.04.023

Good practice recommendations for the use of time-lapse technology(dagger)
technology Eshre Working group on Time-lapse, Apter S, Ebner T, Freour T, Guns Y, Kovacic B, Le Clef N, Marques M, Meseguer M, Montjean D, Sfontouris I, Sturmey R, Coticchio G,

Hum Reprod Open. 2020 Mar. doi: 10.1093/hropen/hoaa008

Blastocyst collapse as an embryo marker of low implantation potential: a time-lapse multicentre study
Sciorio R, Herrer Saura R, Thong K J, Esbert M, Pickering S J, Meseguer M,

Zygote. 2020 Jan 13. doi: 10.1017/S0967199419000819

Embryo morphokinetics analysis and reproductive outcomes with assisted oocyte activation by a calcium ionophore after prior fertilization failure. A multicentric retrospective study
Aguilar J, Munoz E, Alegre L, Larreategui Z, Remohi J, Meseguer M,

Medicina Reproductiva y Embriología Clínica. 2020 doi: 10.1016/j.medre.2020.10.001

Time of morulation and trophectoderm quality are predictors of a live birth after euploid blastocyst transfer: a multicenter study
Rienzi L, Cimadomo D, Delgado A, Minasi M G, Fabozzi G, Gallego R D, Stoppa M, Bellver J, Giancani A, Esbert M, Capalbo A, Remohi J, Greco E, Ubaldi F M, Meseguer M,

Fertil Steril. 2019 Dec. doi: 10.1016/j.fertnstert.2019.07.1322

Noninvasive embryo assessment: how close are we?
Diaz-Gimeno P, Meseguer M,

Fertil Steril. 2019 Nov. doi: 10.1016/j.fertnstert.2019.09.005

Sperm chromosomal abnormalities and their contribution to human embryo aneuploidy
Rodrigo L, Meseguer M, Mateu E, Mercader A, Peinado V, Bori L, Campos-Galindo I, Milan M, Garcia-Herrero S, Simon C, Rubio C,

Biol Reprod. 2019 Dec 24. doi: 10.1093/biolre/ioz125

Deep learning enables robust assessment and selection of human blastocysts after in vitro fertilization
Khosravi P, Kazemi E, Zhan Q, Malmsten J E, Toschi M, Zisimopoulos P, Sigaras A, Lavery S, Cooper L A D, Hickman C, Meseguer M, Rosenwaks Z, Elemento O, Zaninovic N, Hajirasouliha I,

NPJ Digit Med. 2019 doi: 10.1038/s41746-019-0096-y

A Strength, Weaknesses, Opportunities and Threats analysis on time lapse
Basile N, Elkhatib I, Meseguer M,

Curr Opin Obstet Gynecol. 2019 Jun. doi: 10.1097/GCO.0000000000000534

Novel noninvasive embryo selection algorithm combining time-lapse morphokinetics and oxidative status of the spent embryo culture medium
Alegre L, Del Gallego R, Arrones S, Hernandez P, Muñoz M, Meseguer M,

Fertil Steril. 2019 May. doi: 10.1016/j.fertnstert.2019.01.022

A new system of sperm cryopreservation: evaluation of survival, motility, DNA oxidation, and mitochondrial activity
Pabon D, Meseguer M, Sevillano G, Cobo A, Romero J L, Remohi J, de Los Santos M J,

Andrology. 2019 May. doi: 10.1111/andr.12607

Time-lapse imaging: the state of the artdagger
Gallego R D, Remohi J, Meseguer M,

Biol Reprod. 2019 Dec 24. doi: 10.1093/biolre/ioz035

A comparison of morphokinetic markers predicting blastocyst formation and implantation potential from two large clinical data sets
Zaninovic N, Nohales M, Zhan Q, de Los Santos Z M J, Sierra J, Rosenwaks Z, Meseguer M,

J Assist Reprod Genet. 2019 Apr. doi: 10.1007/s10815-018-1396-x

Effect of oocyte morphology on post-warming survival and embryo development in vitrified autologous oocytes
Coello A, Sanchez E, Vallejo B, Meseguer M, Remohi J, Cobo A,

Reprod Biomed Online. 2019 Mar. doi: 10.1016/j.rbmo.2018.11.028

High sperm DNA fragmentation delays human embryo kinetics when oocytes from young and healthy donors are microinjected
Esbert M, Pacheco A, Soares S R, Amoros D, Florensa M, Ballesteros A, Meseguer M,

Andrology. 2018 Sep. doi: 10.1111/andr.12551

Let's rescue oocytes: in vitro maturation 2.0 is coming
Escrich L, Pellicer A, Meseguer M,

Fertil Steril. 2018 Sep. doi: 10.1016/j.fertnstert.2018.05.019

Sperm lipidic profiles differ significantly between ejaculates resulting in pregnancy or not following intracytoplasmic sperm injection
Rivera-Egea R, Garrido N, Sota N, Meseguer M, Remohi J, Dominguez F,

J Assist Reprod Genet. 2018 Nov. doi: 10.1007/s10815-018-1284-4

Better together than alone: the cumulus benefits
Meseguer M, Hickman C, Pellicer A,

Fertil Steril. 2018 May. doi: 10.1016/j.fertnstert.2018.02.117

Selection of preimplantation embryos using time-lapse microscopy in in vitro fertilization: State of the technology and future directions
Aparicio-Ruiz B, Romany L, Meseguer M,

Birth Defects Res. 2018 1-May. doi: 10.1002/bdr2.1226

To invade, or to observe, that is the question
Meseguer M, Pellicer A,

Fertil Steril. 2018 Apr. doi: 10.1016/j.fertnstert.2018.01.025

Origin and composition of cell-free DNA in spent medium from human embryo culture during preimplantation development
Vera-Rodriguez M, Diez-Juan A, Jimenez-Almazan J, Martinez S, Navarro R, Peinado V, Mercader A, Meseguer M, Blesa D, Moreno I, Valbuena D, Rubio C, Simon C,

Hum Reprod. 2018 Apr 1. doi: 10.1093/humrep/dey028

Variables associated with mitochondrial copy number in human blastocysts: what can we learn from trophectoderm biopsies?
de Los Santos M J, Diez Juan A, Mifsud A, Mercader A, Meseguer M, Rubio C, Pellicer A,

Fertil Steril. 2018 Jan. doi: 10.1016/j.fertnstert.2017.09.022

Comparison of the SwimCount Home Diagnostic Test with Conventional Sperm Analysis
Castello D, Garcia-Laez V, Buyru F, Bakiricioglu E, Ebbesen T, Gabrielsen A, Meseguer M,

Advances in Andrology & Gynaecology. 2018 doi:

Assessment of embryo morphology and developmental dynamics by time-lapse microscopy: is there a relation to implantation and ploidy?
Zaninovic N, Irani M, Meseguer M,

Fertil Steril. 2017 Nov. doi: 10.1016/j.fertnstert.2017.10.002

Obstetric and perinatal outcomes of pregnancies conceived with embryos cultured in a time-lapse monitoring system
Insua M F, Cobo A, Larreategui Z, Ferrando M, Serra V, Meseguer M,

Fertil Steril. 2017 Sep. doi: 10.1016/j.fertnstert.2017.06.031

What else can we do? The latest attempt to improve the sperm's path
Meseguer M, Pellicer A,

Fertil Steril. 2017 Sep. doi: 10.1016/j.fertnstert.2017.07.003

Analysis of the morphological dynamics of blastocysts after vitrification/warming: defining new predictive variables of implantation
Coello A, Meseguer M, Galan A, Alegre L, Remohi J, Cobo A,

Fertil Steril. 2017 Oct. doi: 10.1016/j.fertnstert.2017.07.1157

Paving the way for a gold standard of care for infertility treatment: improving outcomes through standardization of laboratory procedures
Schoolcraft W, Meseguer M, Global Fertility Alliance Electronic address alan thornhill igenomix com,

Reprod Biomed Online. 2017 Oct. doi: 10.1016/j.rbmo.2017.06.023

The use of morphokinetic as a predictor of implantation
Tejera A, Aparicio-Ruiz B, Meseguer M,

Minerva Ginecol. 2017 Dec. doi: 10.23736/S0026-4784.17.04098-9

The most well kept secret, embryo culture media: a smart reveal from an expert
Meseguer M, Pellicer A,

Fertil Steril. 2017 Apr. doi: 10.1016/j.fertnstert.2017.02.116

One for all or all for one? The evolution of embryo morphokinetics
Meseguer M, Pellicer A,

Fertil Steril. 2017 Mar. doi: 10.1016/j.fertnstert.2016.11.032

Obstetric and perinatal outcome of babies born from sperm selected by MACS from a randomized controlled trial
Romany L, Garrido N, Cobo A, Aparicio-Ruiz B, Serra V, Meseguer M,

J Assist Reprod Genet. 2017 Feb. doi: 10.1007/s10815-016-0838-6

Type of chromosome abnormality affects embryo morphology dynamics
Del Carmen Nogales M, Bronet F, Basile N, Martinez E M, Linan A, Rodrigo L, Meseguer M,

Fertil Steril. 2017 Jan. doi: 10.1016/j.fertnstert.2016.09.019

How much have we learned from time-lapse in clinical IVF?
Castello D, Motato Y, Basile N, Remohi J, Espejo-Catena M, Meseguer M,

Mol Hum Reprod. 2016 Oct. doi: 10.1093/molehr/gaw056

Automatic time-lapse instrument is superior to single-point morphology observation for selecting viable embryos: retrospective study in oocyte donation
Aparicio-Ruiz B, Basile N, Perez Albala S, Bronet F, Remohi J, Meseguer M,

Fertil Steril. 2016 Nov. doi: 10.1016/j.fertnstert.2016.07.1117

The why, the how and the when of PGS 2.0: current practices and expert opinions of fertility specialists, molecular biologists, and embryologists
Sermon K, Capalbo A, Cohen J, Coonen E, De Rycke M, De Vos A, Delhanty J, Fiorentino F, Gleicher N, Griesinger G, Grifo J, Handyside A, Harper J, Kokkali G, Mastenbroek S, Meldrum D, Meseguer M, Montag M, Munne S, Rienzi L, Rubio C, Scott K, Scott R T, Simon C, Swain J, Treff N, Ubaldi F, Vassena R, Vermeesch J R, Verpoest W, Wells D, Geraedts J,

Mol Hum Reprod. 2016 Aug. doi: 10.1093/molehr/gaw034

Study of nucleation status in the second cell cycle of human embryo and its impact on implantation rate
Aguilar J, Rubio I, Munoz E, Pellicer A, Meseguer M,

Fertil Steril. 2016 Aug. doi: 10.1016/j.fertnstert.2016.03.036

Combination of metabolism measurement and a time-lapse system provides an embryo selection method based on oxygen uptake and chronology of cytokinesis timing
Tejera A, Castello D, de Los Santos J M, Pellicer A, Remohi J, Meseguer M,

Fertil Steril. 2016 Jul. doi: 10.1016/j.fertnstert.2016.03.019

Optimizing the culture environment and embryo manipulation to help maintain embryo developmental potential
Swain J E, Carrell D, Cobo A, Meseguer M, Rubio C, Smith G D,

Fertil Steril. 2016 Mar. doi: 10.1016/j.fertnstert.2016.01.035

A combination of hydroxypropyl cellulose and trehalose as supplementation for vitrification of human oocytes: a retrospective cohort study
Coello A, Campos P, Remohi J, Meseguer M, Cobo A,

J Assist Reprod Genet. 2016 Mar. doi: 10.1007/s10815-015-0633-9

Time-lapse: the remaining questions to be answered
Meseguer M,

Fertil Steril. 2016 Feb. doi: 10.1016/j.fertnstert.2015.12.126

Blastocyst development in single medium with or without renewal on day 3: a prospective cohort study on sibling donor oocytes in a time-lapse incubator
Costa-Borges N, Belles M, Meseguer M, Galliano D, Ballesteros A, Calderon G,

Fertil Steril. 2016 Mar. doi: 10.1016/j.fertnstert.2015.11.038

Morphokinetic analysis and embryonic prediction for blastocyst formation through an integrated time-lapse system
Motato Y, de los Santos M J, Escriba M J, Ruiz B A, Remohi J, Meseguer M,

Fertil Steril. 2016 Feb. doi: 10.1016/j.fertnstert.2015.11.001

Examining potential reasons why euploid blastocysts do not always implant. Part 1. Optimizing the culture environment and embryo manipulation to maintain viability.
Swain J, Carrell D, Cobo A, Meseguer M, Rubio C, Smith G,

Fertil Steril. 2016 doi:

Collapse of blastocysts is strongly related to lower implantation success: a time-lapse study
Marcos J, Perez-Albala S, Mifsud A, Molla M, Landeras J, Meseguer M,

Hum Reprod. 2015 Nov. doi: 10.1093/humrep/dev216

New strategy for diagnosing embryo implantation potential by combining proteomics and time-lapse technologies
Dominguez F, Meseguer M, Aparicio-Ruiz B, Piqueras P, Quinonero A, Simon C,

Fertil Steril. 2015 Oct. doi: 10.1016/j.fertnstert.2015.06.032

Morphokinetics as a predictor of self-correction to diploidy in tripronucleated intracytoplasmic sperm injection-derived human embryos
Grau N, Escrich L, Galiana Y, Meseguer M, Garcia-Herrero S, Remohi J, Escriba M J,

Fertil Steril. 2015 Sep. doi: 10.1016/j.fertnstert.2015.05.024

Time-lapse in the IVF lab: how should we assess potential benefit?
Basile N, Barriere P, Meseguer M, Freour T,

Hum Reprod. 2015 May. doi: 10.1093/humrep/dev045

What does morphokinetics add to embryo selection and in-vitro fertilization outcomes?
Basile N, Caiazzo M, Meseguer M,

Curr Opin Obstet Gynecol. 2015 Jun. doi: 10.1097/GCO.0000000000000166

Diagnosis of human preimplantation embryo viability
Gardner D K, Meseguer M, Rubio C, Treff N R,

Hum Reprod Update. 2015 Nov-Dec. doi: 10.1093/humupd/dmu064

The use of morphokinetics as a predictor of implantation: a multicentric study to define and validate an algorithm for embryo selection
Basile N, Vime P, Florensa M, Aparicio Ruiz B, Garcia-Velasco J A, Remohi J, Meseguer M,

Hum Reprod. 2015 Feb. doi: 10.1093/humrep/deu331

Is there a relationship between time-lapse parameters and embryo sex?
Bronet F, Nogales M C, Martinez E, Ariza M, Rubio C, Garcia-Velasco J A, Meseguer M,

Fertil Steril. 2015 Feb. doi: 10.1016/j.fertnstert.2014.10.050

Systematic review on clinical outcomes following selection of human preimplantation embryos with time-lapse monitoring
Freour T, Basile N, Barriere P, Meseguer M,

Hum Reprod Update. 2015 Jan-Feb. doi: 10.1093/humupd/dmu054

La tecnología del Time-lapse y su aplicación en las clínicas de reproducción asistida.
Meseguer M, Motato M,

ASEBIR. 2015 doi:

The use of morphokinetics as a predictor of implantation: a multicentric study to define and validate an algorithm for embryo selection.
Basile N, Vime P, Florensa M, Aparicio Ruiz B, Garcia-Velasco J A, Remohi J, Meseguer M,

Hum Reprod. 2015 doi:

Time-Lapse in the IVL lab: how should we assess potential benefit
Basile N, Barrière P, Meseguer M, Freour T,

Hum Reprod. 2015 doi:

Removal of annexin V-positive sperm cells for intracytoplasmic sperm injection in ovum donation cycles does not improve reproductive outcome: a controlled and randomized trial in unselected males
Romany L, Garrido N, Motato Y, Aparicio B, Remohi J, Meseguer M,

Fertil Steril. 2014 Dec. doi: 10.1016/j.fertnstert.2014.09.001

Clinical validation of embryo culture and selection by morphokinetic analysis: a randomized, controlled trial of the EmbryoScope
Rubio I, Galan A, Larreategui Z, Ayerdi F, Bellver J, Herrero J, Meseguer M,

Fertil Steril. 2014 Nov. doi: 10.1016/j.fertnstert.2014.07.738

High progesterone levels in women with high ovarian response do not affect clinical outcomes: a retrospective cohort study
Requena A, Cruz M, Bosch E, Meseguer M, Garcia-Velasco J A,

Reprod Biol Endocrinol. 2014 26-Jul. doi: 10.1186/1477-7827-12-69

Ethnicity as a determinant of ovarian reserve: differences in ovarian aging between Spanish and Indian women
Iglesias C, Banker M, Mahajan N, Herrero L, Meseguer M, Garcia-Velasco J A,

Fertil Steril. 2014 Jul. doi: 10.1016/j.fertnstert.2014.03.050

The human first cell cycle: impact on implantation
Aguilar J, Motato Y, Escriba M J, Ojeda M, Munoz E, Meseguer M,

Reprod Biomed Online. 2014 Apr. doi: 10.1016/j.rbmo.2013.11.014

Increasing the probability of selecting chromosomally normal embryos by time-lapse morphokinetics analysis
Basile N, Nogales Mdel C, Bronet F, Florensa M, Riqueiros M, Rodrigo L, Garcia-Velasco J A, Meseguer M,

Fertil Steril. 2014 Mar. doi: 10.1016/j.fertnstert.2013.12.005

High progesterone levels in women with high ovarian response do not affect clinical outcomes: a retrospective cohort study.
Requena A, Cruz M, Bosch E, Meseguer M, Garcia-Velasco J A,

Reprod Biol Endocrinol 2014; 26:69. 2014 doi:

Increasing the probability of selecting chromosomally normal embryos by time-lapse morphokinetic analysis.
Basile N, Bronet F, Nogales MC, Martinez E, Ariza M, Agudo D, Florensa M, Riqueros M, Meseguer M, Riqueros M,

Fertil Steril. 2014 doi:

Removal of annexin V–positive sperm cells for intracytoplasmic sperm injection in ovum donation cycles does not improve reproductive outcome: a controlled and randomized trial in unselected males.
Romany L, Garrido N, Motato Y, Aparicio B, Remohi J, Meseguer M,

Fertil Steril. 2014 doi:

A time to look back: analysis of morphokinetic characteristics of human embryo development.
Herrero J, Tejera A, Albert C, Vidal C, De Los Santos MJ, Meseguer M,

Fertil Steril. 2013 doi:

Assessment of sperm using mRNA microarray technology.
Garrido N, Garcia-Herrero S, Meseguer M,

Fertil Steril. 2013 doi:

Is morphokinetic analysis the answer?
Aparicio B, Cruz M, Meseguer M,

RBM Online. 2013 doi:

Obesity reduces uterine receptivity: clinical experience from 9,587 first cycles of ovum donation with normal weight donors.
Bellver J, Pellicer A, Garcia-Velasco J A, Ballesteros A, Remohi J, Meseguer M,

Fertil Steril. 2013 doi:

Oocyte insemination techniques are related to alterations of embryo developmental timing in an oocyte donation model.
Cruz M, Garrido N, Gadea B, Muñoz M, Perez-Cano I, Meseguer M,

RBM Online. 2013 doi:

PGE2and PGF2? Concentrations in Human Endometrial Fluid as Biomarkers for Embryonic Implantation.
Vilella F, Ramirez L, Berlanga O, Martinez S, Alama P, Meseguer M, Pellicer A, Simon C,

J Clin Endocrinol Metab. 2013 doi:

Selection of high potential embryos using time-lapse imaging: the era of morphokinetics.
Herrero J, Meseguer M,

Fertil Steril. 2013 doi:

Similar morphokinetic patterns in embryos derived from obese and normoweight infertile women: a time-lapse study.
Bellver J, Pellicer A, Garcia-Velasco J A, Ballesteros A, Remohi J, Meseguer M,

Hum Reprod. 2013 doi:

The type of GnRH analogue used during controlled ovarian stimulation influences early embryo developmental kinetics: a time-lapse study.
Muñoz M, Cruz M, Humaidan P, Garrido N, Perez-Cano I, Meseguer M,

Eur J Obstet Gynecol Reprod Biol. 2013 doi:

Type of culture media does not affect embryo kinetics: a time-lapse analysis of sibling oocytes.
Basile N, Morbeck D, Garcia-Velasco J A, Bronet F, Meseguer M,

Hum Reprod. 2013 doi:

Embryo incubation and selection in a time-lapse monitoring system improves pregnancy outcome compared with a standard incubator: a retrospective cohort study
Meseguer M, Rubio I, Cruz M, Basile N, Marcos J, Requena A,

Fertil Steril. 2012 Dec. doi: 10.1016/j.fertnstert.2012.08.016

Limited implantation success of direct-cleaved human zygotes: a time-lapse study
Rubio I, Kuhlmann R, Agerholm I, Kirk J, Herrero J, Escriba M J, Bellver J, Meseguer M,

Fertil Steril. 2012 Dec. doi: 10.1016/j.fertnstert.2012.07.1135

Dose of recombinant FSH and oestradiol concentration on day of HCG affect embryo development kinetics
Muñoz M, Cruz M, Humaidan P, Garrido N, Perez-Cano I, Meseguer M,

Reprod Biomed Online. 2012 Oct. doi: 10.1016/j.rbmo.2012.06.016

Timing of cell division in human cleavage-stage embryos is linked with blastocyst formation and quality
Cruz M, Garrido N, Herrero J, Perez-Cano I, Muñoz M, Meseguer M,

Reprod Biomed Online. 2012 Oct. doi: 10.1016/j.rbmo.2012.06.017

Time-dependent O2 consumption patterns determined optimal time ranges for selecting viable human embryos
Tejera A, Herrero J, Viloria T, Romero J L, Gamiz P, Meseguer M,

Fertil Steril. 2012 Oct. doi: 10.1016/j.fertnstert.2012.06.040

Full in vitro fertilization laboratory mechanization: toward robotic assisted reproduction?
Meseguer M, Kruhne U, Laursen S,

Fertil Steril. 2012 Jun. doi: 10.1016/j.fertnstert.2012.03.013

A review of recent trials selecting viable embryos for transfer: comprehensive time-lapse imaging analysis.
Rubio I, Herrero J, Meseguer M,

Eur J Obstet Gynaecol. 2012 doi:

Dose of recombinant FSH and estradiol concentration on day of HCG affect embryo development kinetics.
Muñoz M, Cruz M, Humaidan P, Garrido N, Perez-Cano I, Meseguer M,

RBM Online. 2012 doi:

El futuro de la reproducción son los incubadores con un sistema de time-lapse?
Tejera A, Meseguer M,

ASEBIR. 2012 doi:

Evaluation of embryo quality: Time-lapse imaging to assess embryo morphokinesis.
Basile N, Garcia-Velasco J A, Meseguer M,

Textbook of Assisted Reproductive Techniques. 2012 doi:

Increasing the success of assisted reproduction by defining sperm fertility markers and selecting sperm with the best molecular profile.
Rivera R, Meseguer M, Garrido N,

Expert Rev Obstet Gynecol. 2012 doi:

Time-lapse technology: evaluation of embryo quality and new markers for embryo selection.
Basile N, Meseguer M,

Expert Rev Obstet Gynecol. 2012 doi:

Timing of cell divisions in human cleavage stage embryos correlate with blastocyst formation and quality.
Cruz M, Garrido N, Herrero J, Perez-Cano I, Muñoz M, Meseguer M,

RBM Online. 2012 doi:

Report of results obtained in 2,934 women using donor sperm: donor insemination versus in vitro fertilization according to indication
Viloria T, Garrido N, Minaya F, Remohi J, Muñoz M, Meseguer M,

Fertil Steril. 2011 Nov. doi: 10.1016/j.fertnstert.2011.08.016

The use of morphokinetics as a predictor of embryo implantation
Meseguer M, Herrero J, Tejera A, Hilligsoe K M, Ramsing N B, Remohi J,

Hum Reprod. 2011 Oct. doi: 10.1093/humrep/der256

Adenomyosis does not affect implantation, but is associated with miscarriage in patients undergoing oocyte donation
Martinez-Conejero J A, Morgan M, Montesinos M, Fortuno S, Meseguer M, Simon C, Horcajadas J A, Pellicer A,

Fertil Steril. 2011 Oct. doi: 10.1016/j.fertnstert.2011.07.1088

Oxygen consumption is a quality marker for human oocyte competence conditioned by ovarian stimulation regimens
Tejera A, Herrero J, de Los Santos M J, Garrido N, Ramsing N, Meseguer M,

Fertil Steril. 2011 Sep. doi: 10.1016/j.fertnstert.2011.06.059

Embryo quality, blastocyst and ongoing pregnancy rates in oocyte donation patients whose embryos were monitored by time-lapse imaging
Cruz M, Gadea B, Garrido N, Pedersen K S, Martinez M, Perez-Cano I, Muñoz M, Meseguer M,

J Assist Reprod Genet. 2011 Jul. doi: 10.1007/s10815-011-9549-1

Aplicación de la tecnología del embryoscope para la cuentificación de la calidad ovocitaria mediante el análisis de los patrones de respiración.
Herrero J, Tejera A, Cruz M, Meseguer M,

ASEBIR. 2011 doi:

Cinematografía para el estudio de la calidad embrionaria. Embryoscope
Herrero J, Tejera A, Cruz M, Meseguer M,

ASEBIR. 2011 doi:

Differential transcriptomic profile in spermatozoa achieving pregnancy or not via ICSI.
Garcia-Herrero S, Garrido N, Martinez-Conejero JA, Remohi J, Pellicer A, Meseguer M,

RBM Online. 2011 doi:

Effect of sperm DNA fragmentation on pregnancy outcome depends on oocyte quality
Meseguer M, Santiso R, Garrido N, Garcia-Herrero S, Remohi J, Fernandez JL,

Fertil Steril. 2011 doi:

A prospective, randomized, controlled trial comparing three different gonadotropin regimens in oocyte donors: ovarian response, in vitro fertilization outcome, and analysis of cost minimization.
Melo M, Bellver J, Garrido N, Meseguer M, Pellicer A, Remohi J,

Fertil Steril. 2010 doi:

Antral follicle count (AFC) can be used in the prediction of ovarian response but cannot predict the oocyte/embryo quality or the in vitro fertilization outcome in an egg donation program.
Barreto Melo MA, Garrido N, Alvarez C, Bellver J, Meseguer M, Pellicer A, Remohi J,

Fertil Steril. 2010 doi:

Cigarette smoking affects specific sperm oxidative defenses but does not cause oxidative DNA damage in infertile men.
Viloria T, Meseguer M, Martinez-Conejero JA, O'Connor JE, Remohi J, Pellicer A, Garrido N,

Fertil Steril. 2010 doi:

Female Obesity impairs in vitro fertilization outcome without affecting embryo quality.
Bellver J, Ayllon Y, Ferrando M, Melo M, Goyri E, Pellicer A, Remohi J, Meseguer M,

Female Fertil Steril. 2010 doi:

La obesidad en las mujeres afecta los resultados de fertilización in vitro pero no la calidad embrionaria.
Bellver J, Y Aillon, M Ferrando, M Melo, E Goyri, Pellicer A, Remohi J, Meseguer M,

Revista Iberoamericana de Fertilidad y Reproducción Humana. 2010 doi:

Las muestras de semen de pacientes infértiles que se someten a una ICSI o IAH difieren considerablemente en sus perfiles de expresión génica
Garcia-Herrero S, Garrido N, Pellicer A, Remohi J, Martinez-Conejero JA, Meseguer M,

Revista del Laboratorio Clínico. 2010 doi:

Morphologic indicators predict the stage of chromatin condensation of human germinal vesicle oocytes recovered from stimulated cycles.
Escrich L, Grau N, Meseguer M, Pellicer A, Escriba M J,

Fertil Steril. 2010 doi:

Ontological evaluation of transcriptional differences between sperm of infertile males and fertile donors using microarray analysis.
Garcia-Herrero S, Garrido N, Martinez-Conejero JA, Remohi J, Pellicer A, Meseguer M,

J Assist Reprod Genet. 2010 doi:

Perfiles de expresión génica en hombres infértiles que se someten a reproducción asistida.
Garcia-Herrero S, Meseguer M, Martinez-Conejero JA, Remohi J, Pellicer A, Garrido N,

Fertil Steril. 2010 doi:

Pregnancy rates alter incubation in new time-lapse incubator (embryoscope) providing detailed information about embryo development compared to incubation in a standard incubator
Meseguer M, Hilligsøe KM, Pedersen KS, Herrero J, Tejera A, Garrido N,

Fertil Steril. 2010 doi:

Profound Transcriptomic Differences Found between Sperm Samples from Sperm Donors vs. Patients Undergoing Assisted Reproduction Techniques Tends to Disappear after Swim-up Sperm Preparation Technique.
Garcia-Herrero S, Garrido N, Pellicer A, Remohi J, Martinez-Conejero JA, Meseguer M,

J Assist Reprod Genet. 2010 doi:

Relevance of testicular sperm DNA oxidation for the outcome of ovum donation cycles.
Aguilar C, Meseguer M, Garcia-Herrero S, Gil-Salom M, O'Connor JE, Garrido N,

Fertil Steril. 2010 doi:

Simultaneous determination in situ of DNA fragmentation and 8-oxoguanine in human sperm.
Santiso R, Tamayo M, Gosalvez J, Meseguer M, Garrido N, Fernandez JL,

Fertil Steril. 2010 doi:

Swim-up procedure selects spermatozoa with longer telomere length.
Santiso R, Tamayo M, Gosalvez J, Meseguer M, Garrido N, Fernandez JL,

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 2010 doi:

The transcriptome of spermatozoa used in homologous intrauterine insemination varies considerably between samples that achieve pregnancy and those that do not.
Garcia-Herrero S, Meseguer M, Martinez-Conejero JA, Remohi J, Pellicer A, Garrido N,

Fertil Steril. 2010 doi:

Use of cryo-banked oocytes in an ovum donation programme: a prospective, randomized, controlled, clinical trial.
Cobo A, Meseguer M, Remohi J, Pellicer A,

Hum Reprod. 2010 doi:

Y chromosome microdelections, sperm DNA fragmentation andsperm oxidative as causes of recurrent of unknown etiology.
Bellver J, Meseguer M, Muriel L, Garcia-Herrero S, Barreto MA, Grada AL, Remohi J, Pellicer A, Garrido N, Pellicer A,

Hum Reprod. 2010 doi:

Y chromosome microdeletions, sperm DNA fragmentation and sperm oxidative stress as causes of recurrent spontaneous abortion of unknown etiology.
Bellver J, Meseguer M, Muriel L, Garcia-Herrero S, Barreto MAM, Garda AL, Remohi J, Pellicer A, Garrido N, Pellicer A,

Hum Reprod. 2010 doi:

Biochemical markers of male infertility: the key role of DNA damage.
Aguilar C, Garrido N, Viloria T, Fernandez JL, Meseguer M,

Expert Rev Obstet Gynecol. 2009 doi:

Bleeding during transfer is the only parameter of patient anatomy and embryo quality that affects reproductive outcome: a prospective study.
Muñoz M, Meseguer M, Lizan C, Ayllon Y, Perez-Cano I, Garrido N,

Fertil Steril. 2009 doi:

First report of the absence of viral load in testicular sperm samples obtained from men with hepatitis C and HIV after washing and their subsequent use.
Garrido N, Gil-Salom M, Martinez-Jabaloyas JM, Meseguer M,

Fertil Steril. 2009 doi:

GnRH agonist versus recombinant HCG in an oocyte donation programme: a randomized, prospective, controlled, assessor-blind study.
Melo M, Busso CE, Bellver J, Alama P, Garrido N, Meseguer M, Pellicer A, Remohi J,

RBM Online. 2009 doi:

Integridad del ADN y patrón de expresión génica indicadores de calidad espermática y éxito reproductivo
Meseguer M, Garcia-Herrero S, Aguilar C, Viloria T, Garrido N,

ASEBIR. 2009 doi:

Métodos de selección objetiva de espermatozoides competentes.
Romany L, Meseguer M, Remohi J, Pellicer A, Garrido N,

Revista Iberoamericana de Fertilidad y Reproducción Humana. 2009 doi:

Métodos para la selección objetiva de espermatozoides competentes
Romany L, Meseguer M, Remohi J, Pellicer A, Garrido N,

Revista Iberoamericana de Fertilidad y Reproducción Humana. 2009 doi:

Microarray analysis in sperm from fertile and infertile men without basic sperm analysis abnormalities reveals a significantly different transcriptome.
Garrido N, Martinez-Conejero JA, Jauregui J, Horcajadas J A, Simon C, Remohi J, Meseguer M,

Fertil Steril. 2009 doi:

Nuevos métodos de selección embrionaria: una nueva tendencia para transferencias únicas.
Herrero J, Tejera A, De Los Santos MJ, Garrido N, Ramsing N, Meseguer M,

Revista Iberoamericana de Fertilidad y Reproducción Humana. 2009 doi:

Sperm DNA fragmentation levels in testicular sperm samples from azoospermic males as assessed by the sperm chromatin dispersion (SCD) test.
Meseguer M, Santiso R, Garrido N, Gil-Salom M, Remohi J, Fernandez J,

Fertil Steril. 2009 doi:

Contribution of sperm molecular features to embryo quality and assisted reproduction success
Garrido N, Remohi J, Martinez-Conejero J A, Garcia-Herrero S, Pellicer A, Meseguer M,

Reprod Biomed Online. 2008 Dec. doi: 10.1016/s1472-6483(10)60415-4

Influence of paternal age on assisted reproduction outcome
Bellver J, Garrido N, Remohi J, Pellicer A, Meseguer M,

Reprod Biomed Online. 2008 Nov. doi: 10.1016/s1472-6483(10)60305-7

Endometrial receptivity and implantation are not affected by the presence of uterine intramural leiomyomas: a clinical and functional genomics analysis
Horcajadas J A, Goyri E, Higon M A, Martinez-Conejero J A, Gambadauro P, Garcia G, Meseguer M, Simon C, Pellicer A,

J Clin Endocrinol Metab. 2008 Sep. doi: 10.1210/jc.2008-0565

The effect of cancer on sperm DNA fragmentation as measured by the sperm chromatin dispersion test
Meseguer M, Santiso R, Garrido N, Fernandez J L,

Fertil Steril. 2008 Jul. doi: 10.1016/j.fertnstert.2007.06.026

MUC1 in human testis and ejaculated spermatozoa and its relationship to male fertility status
Martinez-Conejero J A, Garrido N, Remohi J, Pellicer A, Simon C, Meseguer M,

Fertil Steril. 2008 Aug. doi: 10.1016/j.fertnstert.2007.06.104

The significance of sperm DNA oxidation in embryo development and reproductive outcome in an oocyte donation program: a new model to study a male infertility prognostic factor
Meseguer M, Martinez-Conejero J A, O'Connor J E, Pellicer A, Remohi J, Garrido N,

Fertil Steril. 2008 May. doi: 10.1016/j.fertnstert.2007.05.005

Human immunodeficiency type-1 virus (HIV-1) infection in serodiscordant couples (SDCs) does not have an impact on embryo quality or intracytoplasmic sperm injection (ICSI) outcome
Melo M A, Meseguer M, Bellver J, Remohi J, Pellicer A, Garrido N,

Fertil Steril. 2008 Jan. doi: 10.1016/j.fertnstert.2007.02.004

Sperm selection by swim-up in terms of deoxyribonucleic acid fragmentation as measured by the sperm chromatin dispersion test is altered in heavy smokers
Viloria T, Garrido N, Fernandez J L, Remohi J, Pellicer A, Meseguer M,

Fertil Steril. 2007 Aug. doi: 10.1016/j.fertnstert.2006.11.135

The human sperm glutathione system: a key role in male fertility and successful cryopreservation
Meseguer M, Martinez-Conejero J A, Muriel L, Pellicer A, Remohi J, Garrido N,

Drug Metab Lett. 2007 Apr. doi: 10.2174/187231207780363633

Improvements achieved in an oocyte donation program over a 10-year period: sequential increase in implantation and pregnancy rates and decrease in high-order multiple pregnancies
Budak E, Garrido N, Soares S R, Melo M A, Meseguer M, Pellicer A, Remohi J,

Fertil Steril. 2007 Aug. doi: 10.1016/j.fertnstert.2006.11.118

Ovarian stimulation length, number of follicles higher than 17 mm and estradiol on the day of human chorionic gonadotropin administration are risk factors for multiple pregnancy in intrauterine insemination
Garrido N, Melo MAB, Simon C, Remohi J, Pellicer A, Meseguer M,

Reproductive Medicine and Biology. 2007 doi:

The effectiveness of modified sperm washes in severely oligoasthenozoospermic men infected with human immunodeficiency and hepatitis C viruses
Garrido N, Remohi J, Pellicer A, Meseguer M,

Fertil Steril. 2006 Nov. doi: 10.1016/j.fertnstert.2006.03.061

Effect of sperm glutathione peroxidases 1 and 4 on embryo asymmetry and blastocyst quality in oocyte donation cycles
Meseguer M, de los Santos M J, Simon C, Pellicer A, Remohi J, Garrido N,

Fertil Steril. 2006 Nov. doi: 10.1016/j.fertnstert.2006.03.053

The significance of premature luteinization in an oocyte-donation programme
Melo M A, Meseguer M, Garrido N, Bosch E, Pellicer A, Remohi J,

Hum Reprod. 2006 Jun. doi: 10.1093/humrep/dei474

Value of the sperm deoxyribonucleic acid fragmentation level, as measured by the sperm chromatin dispersion test, in the outcome of in vitro fertilization and intracytoplasmic sperm injection
Muriel L, Garrido N, Fernandez J L, Remohi J, Pellicer A, de los Santos M J, Meseguer M,

Fertil Steril. 2006 Feb. doi: 10.1016/j.fertnstert.2005.07.1327

Sperm cryopreservation in oncological patients: a 14-year follow-up study
Meseguer M, Molina N, Garcia-Velasco J A, Remohi J, Pellicer A, Garrido N,

Fertil Steril. 2006 Mar. doi: 10.1016/j.fertnstert.2005.08.022

Use of washed sperm for assisted reproduction in HIV-positive males without checking viral absence. A risky business?
Garrido N, Meseguer M,

Hum Reprod. 2006 Feb. doi: 10.1093/humrep/dei337

Value of the sperm chromatin dispersion test in predicting pregnancy outcome in intrauterine insemination: a blind prospective study
Muriel L, Meseguer M, Fernandez J L, Alvarez J, Remohi J, Pellicer A, Garrido N,

Hum Reprod. 2006 Mar. doi: 10.1093/humrep/dei403

Aumento de la fragmentación del ADN espermático en los fumadores tras la capacitación mediante swim-up.
Viloria T, Garrido N, Fernandez JL, Remohi J, Pellicer A, Muriel L, Meseguer M,

ASEBIR. 2006 doi:

De la fragmentación del DNA espermático en los fumadores tras la capacitación mediante swim-up.
Viloria T, Garrido N, Fernandez J, Remohi J, Pellicer A, Muriel L, Meseguer M,

ASEBIR. 2006 doi:

Estudio comparativo de dos medios de cultivo HTF e ISM-1: implicaciones en el fenotipo embrionario y resultados clínicos.
Gimeno L, Lopez MA, Meseguer M, Santos JM, Pellicer A, Remohi J, Santos MJ,

Revista Iberoamericana de Fertilidad y Reproducción Humana. 2006 doi:

Interpretation of sperm morphology analysis in gynecological practice for infertility.
Garrido N, Meseguer M, Pellicer A,

Expert Rev Obstet Gynecol. 2006 doi:

Value of the sperm deoxyribonucleic acid fragmentation level, as measured by the sperm chromatin dispersion test, in the outcome of in vitro fertilization and intracytoplasmic sperm injection.
Muriel L, Garrido N, Fernandez JL, Remohi J, Pellicer A, De Los Santos MJ, Meseguer M,

Fertil Steril. 2006 doi:

Smoking habits of parents and male: female ratio in spermatozoa and preimplantation embryos
Viloria T, Rubio M C, Rodrigo L, Calderon G, Mercader A, Mateu E, Meseguer M, Remohi J, Pellicer A,

Hum Reprod. 2005 Sep. doi: 10.1093/humrep/dei087

Semen characteristics in human immunodeficiency virus (HIV)- and hepatitis C (HCV)-seropositive males: predictors of the success of viral removal after sperm washing
Garrido N, Meseguer M, Remohi J, Simon C, Pellicer A,

Hum Reprod. 2005 Apr. doi: 10.1093/humrep/deh699

Value of the sperm chromatin dispersion test in predicting pregnancy outcome in intrauterine insemination: a blind prospective study.
Muriel L, Meseguer M, Fernandez JL, Alvarez J, Remohi J, Remohi J, Pellicer A, Garrido N,

Hum Reprod. 2005 doi:

Relationship between standard semen parameters, calcium, cholesterol contents, and mitochondrial activity in ejaculated spermatozoa from fertile and infertile males
Meseguer M, Garrido N, Martinez-Conejero J A, Simon C, Pellicer A, Remohi J,

J Assist Reprod Genet. 2004 Dec. doi: 10.1007/s10815-004-8761-7

Relationship among standard semen parameters, glutathione peroxidase/glutathione reductase activity, and mRNA expression and reduced glutathione content in ejaculated spermatozoa from fertile and infertile men
Garrido N, Meseguer M, Alvarez J, Simon C, Pellicer A, Remohi J,

Fertil Steril. 2004 Oct. doi: 10.1016/j.fertnstert.2004.04.033

Report of the results of a 2 year programme of sperm wash and ICSI treatment for human immunodeficiency virus and hepatitis C virus serodiscordant couples
Garrido N, Meseguer M, Bellver J, Remohi J, Simon C, Pellicer A,

Hum Reprod. 2004 Nov. doi: 10.1093/humrep/deh460

Concentration of glutathione and expression of glutathione peroxidases 1 and 4 in fresh sperm provide a forecast of the outcome of cryopreservation of human spermatozoa
Meseguer M, Garrido N, Simon C, Pellicer A, Remohi J,

J Androl. 2004 Sep-Oct. doi: 10.1002/j.1939-4640.2004.tb02855.x

Parameters affecting the results in a program of artificial insemination with donor sperm. A 12-year retrospective review of more than 1800 cycles
Zuzuarregui J L, Meseguer M, Garrido N, Simon C, Pellicer A, Remohi J,

J Assist Reprod Genet. 2004 Apr. doi: 10.1023/b:jarg.0000029494.55273.a2

Testicular sperm extraction (TESE) and intracytoplasmic sperm injection (ICSI) in hypogonadotropic hypogonadism with persistent azoospermia after hormonal therapy
Meseguer M, Garrido N, Remohi J, Pellicer A, Gil-Salom M,

J Assist Reprod Genet. 2004 Mar. doi: 10.1023/b:jarg.0000027021.66435.02

Reproductive issues for persons with HIV
Garrido N, Meseguer M, Bellver J,

Am J Obstet Gynecol. 2004 May. doi: 10.1016/j.ajog.2003.12.055

Pro-oxidative and anti-oxidative imbalance in human semen and its relation with male fertility
Garrido N, Meseguer M, Simon C, Pellicer A, Remohi J,

Asian J Androl. 2004 Mar. doi:

Role of cholesterol, calcium, and mitochondrial activity in the susceptibility for cryodamage after a cycle of freezing and thawing
Meseguer M, Garrido N, Martinez-Conejero J A, Simon C, Pellicer A, Remohi J,

Fertil Steril. 2004 Mar. doi: 10.1016/j.fertnstert.2003.09.035

Assisted reproduction in HIV and HCV infected men of serodiscordant couples
Garrido N, Meseguer M, Simon C, Pellicer A, Remohi J,

Arch Androl. 2004 Mar-Apr. doi:

Affecting the Results in a Program of Artificial Insemination With Donor Sperm. A 12-year Retrospective Review of More Than 1800 Cycles.
Zuzuarregui JL, Meseguer M, Garrido N, Simon C, Pellicer A, Remohi J, Parameters,

Parameters J Assist Reprod Genet. 2004 doi:

Ca+2 and cholesterol and mitochondrial activity in sperm from fertile and infertile men.
Meseguer M, Garrido N, Martinez-Conejero JA, Simon C, Pellicer A, Remohi J,

Fertil Steril. 2004 doi:

MUC1 e IL-6: posibles marcadores de fertilidad en reproducción humana.
Martinez-Conejero J, Garrido N, Simon C, Pellicer A, Remohi J, Meseguer M,

ASEBIR. 2004 doi:

Testicular sperm extraction (TESE) and ICSI in patients with permanent azoospermia after chemotherapy
Meseguer M, Garrido N, Remohi J, Pellicer A, Simon C, Martinez-Jabaloyas J M, Gil-Salom M,

Hum Reprod. 2003 Jun. doi: 10.1093/humrep/deg260

Transmembrane and truncated (SEC) isoforms of MUC1 in the human endometrium and Fallopian tube
Hey N A, Meseguer M, Simon C, Smorodinsky N I, Wreschner D H, Ortiz M E, Aplin J D,

Reprod Biol Endocrinol. 2003 Jan 30. doi: 10.1186/1477-7827-1-2

Human immunodeficiency virus (HIV) and Hepatitis C virus (HCV) presence in washed semen: are they absent or present although non-infective.
Meseguer M, Garrido N,

ART and Science Clave. 2003 doi:

Parámetros que afectan a los resultados de la inseminación artificial con semen de donante.
Zuzuarregui JL, Garrido N, Meseguer M, Simon C, Pellicer A, Remohi J,

Revista Iberoamericana de Fertilidad y Reproducción Humana. 2003 doi:

Premio al mejor artículo original publicado en la Revista Iberoamericana de Fertilidad. TGF-?1 regula in vitro a la mucina endometrial humana MUC1 durante la implantación embrionaria.
Meseguer M, Martinez-Conejero J, Remohi J, Aplin J, Pellicer A, Remohi J,

Revista Iberoamericana de Fertilidad y Reproducción Humana. 2003 doi:

To the editor, regarding Williams et al.,
Garrido N, Meseguer M, Bellver J,

Am J Obstet Gynecol. 2003 doi:

Flow cytometry in human reproductive biology
Garrido N, Meseguer M, Remohi J, Pellicer A, Simon C,

Gynecol Endocrinol. 2002 Dec. doi:

Comparison of polymerase chain reaction-dependent methods for determining the presence of human immunodeficiency virus and hepatitis C virus in washed sperm
Meseguer M, Garrido N, Gimeno C, Remohi J, Simon C, Pellicer A,

Fertil Steril. 2002 Dec. doi: 10.1016/s0015-0282(02)04275-9

Sperm and oocyte donor selection and management: experience of a 10 year follow-up of more than 2100 candidates
Garrido N, Zuzuarregui J L, Meseguer M, Simon C, Remohi J, Pellicer A,

Hum Reprod. 2002 Dec. doi: 10.1093/humrep/17.12.3142

Gender selection: ethical, scientific, legal, and practical issues
Meseguer M, Garrido N, Remohi J, Simon C, Pellicer A,

J Assist Reprod Genet. 2002 Sep. doi: 10.1023/a:1016876026359

In vitro fertilization with intracytoplasmic sperm injection for human immunodeficiency virus-1 serodiscordant couples
Garrido N, Meseguer M, Bellver J,

Am J Obstet Gynecol. 2002 Oct. doi: 10.1067/mob.2002.128516

Hormonal and embryonic regulation of chemokines IL-8, MCP-1 and RANTES in the human endometrium during the window of implantation
Caballero-Campo P, Dominguez F, Coloma J, Meseguer M, Remohi J, Pellicer A, Simon C,

Mol Hum Reprod. 2002 Apr. doi: 10.1093/molehr/8.4.375

A. Gender selection: ethical, scientific, legal, and practical issues
Meseguer M, Garrido N, Remohi J, Simon C, Pellicer A,

J Assist Reprod Genet. 2002 doi:

Análise do DNA do espermatozóide humano por citometria de fluxo (CF)
Garrido N, Meseguer M, Soares S R, Simon C, Pellicer A, Remohi J,

Reproduçao e Climaterio. 2002 doi:

Comparison of polymerase chain reaction–dependent methods for determining the presence of human immunodeficiency virus and hepatitis C virus in washed sperm.
Meseguer M, Garrido N, Gimeno C, Remohi J, Simon C, Pellicer A,

Fertil Steril. 2002 doi:

Factor Masculino y. Técnicas de Reproducción Asistida.
Garrido N, Meseguer M, Gamiz P, Simon C, Pellicer A, Remohi J,

ASEBIR. 2002 doi:

Factores influyentes en los resultados de la congelación y descongelación del semen humano.
Garrido N, Meseguer M, Simon C, Pellicer A, Remohi J,

ASEBIR. 2002 doi:

Testicular sperm extraction (TESE) and intracytoplasmic sperm injection (ICSI) results in secondary azoospermic patients after chemotherapy.
Garrido N, Meseguer M, Gil-Salom M, Simon C, Remohi J, Pellicer A,

Fertil Steril. 2002 doi:

MUC1, glycans and the cell-surface barrier to embryo implantation
Aplin J D, Meseguer M, Simon C, Ortiz M E, Croxatto H, Jones C J,

Biochem Soc Trans. 2001 May. doi: 10.1042/0300-5127:0290153

Human endometrial mucin MUC1 is up-regulated by progesterone and down-regulated in vitro by the human blastocyst
Meseguer M, Aplin J D, Caballero-Campo P, O'Connor J E, Martin J C, Remohi J, Pellicer A, Simon C,

Biol Reprod. 2001 Feb. doi: 10.1095/biolreprod64.2.590

Detección del virus de la Hepatitis C en semen lavado de varones seropositivos para su posterior uso en reproducción asistida: resultados preliminares.
Garrido N, Meseguer M, Simon C, Pellicer A, Remohi J,

Actualidad Andrológic. 2001 doi:

Es segura la utilización del semen de donante? Seguimiento de enfermedades infecciosas y desórdenes hereditarios en la población de donantes de semen y el programa de IAD; experiencia de 10 años
Meseguer M, Garrido N, Simon C, Pellicer A, Remohi J,

Actualidad Andrológica. 2001 doi:

Increased adhesiveness in cultured endometrial-derived cells is related to the absence of moesin expression
Martin J C, Jasper M J, Valbuena D, Meseguer M, Remohi J, Pellicer A, Simon C,

Biol Reprod. 2000 Nov. doi: 10.1095/biolreprod63.5.1370

Embryonic regulation of endometrial molecules in human implantation
Simon C, Martin J C, Meseguer M, Caballero-Campo P, Valbuena D, Pellicer A,

J Reprod Fertil Suppl. 2000 doi:

O-126. Embryonic regulation of MCP-1 in human endometrial epithelial cells.
Caballero-Campo P, Meseguer M, Martin JC, Coloma J, O'Connor JE, Remohi J, Pellicer A, Simon C,

Hum Reprod. 1999 doi:

MUC1 and endometrial receptivity.
Meseguer M,

Mol Hum Reprod. 1998 doi:

Presentations

Tejera A Alegre L Mifsud A De los Santos JM Esbert M Meseguer M P-21 ASSISTED HATCHING (AH) IN COLLAPSED BLASTOCYSTS IS ABLE TO RESTORE THE IMPLANTATION RATES: A RETROSPECTIVE STUDY. Presented at 76th American Society of Reproductive Medicine Scientific Congress, Virtual congress, October 17-21,2020

Bori L Paya E Valera MA Remohi JA Valery Naranjo Meseguer M P-79 ARTIFICIAL NEURAL NETWORKS APPLIED FOR PREDICTION OF THE IMPLANTATION POTENTIAL BY USING EMBRYO MORPHOLOGY DYNAMICS. Presented at 76th American Society of Reproductive Medicine Scientific Congress, Virtual congress, October 17-21,2020

Alegre L Bori L Valera MA Gouveia Nogueira MF André Satoshi Ferreira Celso Rocha J Meseguer M P-83 FIRST APPLICATION OF ARTIFICIAL NEURONAL NETWORKS FOR HUMAN LIVE BIRTH PREDICTION ON GERI TIME-LAPSE MONITORING SYSTEM BLASTOCYST IMAGES.. Presented at 76th American Society of Reproductive Medicine Scientific Congress, Virtual congress, October 17-21,2020

Cozzolino M Garcia-Velasco JA Meseguer M Pellicer A Bellver J O-153 OBESE WOMEN PRESENT AN INCREASED RISK OF MISCARRIAGE AFTER EUPLOID EMBRYO TRANSFER. Presented at 76th American Society of Reproductive Medicine Scientific Congress, Virtual congress, October 17-21,2020

Romany L Viloria T Aparicio-Ruiz B Diana Beltrán Remohi JA Meseguer M P-81 MACS TECHNOLOGY APPLIED FOR SPERM SELECTION IMPROVES BLASTOCYST QUALITY; A CONTINIOUS EMBRYO MONITORING STUDY.. Presented at 76th American Society of Reproductive Medicine Scientific Congress, Virtual congress, October 17-21,2020

Perez-Albala S Aparicio-Ruiz B Bori L Remohi JA Viloria T Meseguer M P-99 EMBRYO AUTOMATIC DIAGNOSTIC TEST; BLASTULATION, ANEUPLOIDY AND IMPLANTATION RATE PREDICTION. Presented at 76th American Society of Reproductive Medicine Scientific Congress, Virtual congress, October 17-21,2020

Valera MA Albert C Bori L Alegre L Viloria T Meseguer M P-12 HUMID VS DRY CULTURE: DOES RELATIVE HUMIDITY AFFECT THE MORPHOKINETICS OF IN VITRO CULTURED EMBRYOS?. Presented at 76th American Society of Reproductive Medicine Scientific Congress, Virtual congress, October 17-21,2020

Labarta E Rodriguez-Varela C Meseguer M Bori L Delgado A Mercader A Aparicio-Ruiz B Bosch E P-1015 COMPARISON OF THE EMBRYO QUALITY OBTAINED AFTER AN UNSTIMULATED AND STIMULATED CYCLE IN THE SAME INFERTILE PATIENT UNDERGOING IN VITRO FERTILIZATION.. Presented at 76th American Society of Reproductive Medicine Scientific Congress, Virtual congress, October 17-21,2020

Meseguer M 0-164 The application of artificial oocyte activation (AOA) in patients with previous unsuccessful attempt increases the ongoing pregnancy per treatment but not per transfer, a multivariable study.. Presented at the 36th annual meeting of the European Society of Human Reproduction and Embryology, Copenhagen,Denmark, July 5-8, 2020

Valera MA García C Bori L Meseguer M Ferrando M Pellicer A Mol BW Valbuena D Comparison of clinical results of embryo culturing using last generation incubators: is there a better option?. Presented at the 36th annual meeting of the European Society of Human Reproduction and Embryology, Copenhagen,Denmark, July 5-8, 2020